Structural and functional characterization of a highly specific serpin in the insect innate immunity

Journal of Biological Chemistry

Volumn 286, Issue 2, 2011, Pages 1567-1575

  Park, Sun Hee ^a   Jiang, Rui ^a   Piao, Shunfu ^a   Zhang, Bing ^a   Kim, Eun Hye ^a   Kwon, Hyun Mi ^a   Jin, Xiao Ling ^a   Lee, Bok Luel ^a   Ha, Nam Chul ^a  

^a Pusan National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBIN; BIOCHEMICAL STUDIES; FUNCTIONAL CHARACTERIZATION; HEPARIN-BINDING SITE; INNATE IMMUNE RESPONSE; INNATE IMMUNITY; MOLECULAR MECHANISM; NATIVE CONFORMATION; PROXIMITY EFFECTS; REACTIVE CENTER LOOPS; SERINE PROTEASE; SERINE PROTEASE INHIBITOR; SERPINS; SIGNALING CASCADES; SIGNALING PATHWAYS; TENEBRIO MOLITOR;

AMINO ACIDS; BINDING SITES; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYMES; IMMUNOLOGY; MAMMALS; POLYSACCHARIDES; SIGNALING;

CRYSTAL STRUCTURE;

AMIDASE; ANTITHROMBIN; CALCIUM ION; FONDAPARINUX; HEPARIN BINDING PROTEIN; PROTEINASE; SERINE PROTEINASE INHIBITOR; SERPIN SPN48; UNCLASSIFIED DRUG;

ANTICOAGULATION; ARTICLE; BEETLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVITY; GENE OVEREXPRESSION; IN VITRO STUDY; INNATE IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PURIFICATION; SITE DIRECTED MUTAGENESIS; WESTERN BLOTTING; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; ANTITHROMBINS; BINDING SITES; CALCIUM; CRYSTALLOGRAPHY; ENZYME ACTIVATION; HEPARIN; HUMANS; IMMUNITY, INNATE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, TERTIARY; SERPINS; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; TENEBRIO; TOLL-LIKE RECEPTORS;

COLEOPTERA; HEXAPODA; INVERTEBRATA; MAMMALIA; TENEBRIO MOLITOR;

EID: 78651400673     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.144006     Document Type: Article

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