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Volumn 52, Issue 1, 2011, Pages 15-23

Molecular insight into the biology and clinical course of hairy cell leukemia utilizing immunoglobulin gene analysis

Author keywords

cladribine; Hairy cell leukemia; IGH; immunogenetics; prognosis

Indexed keywords

B LYMPHOCYTE RECEPTOR; CLADRIBINE; IMMUNOGLOBULIN; RITUXIMAB;

EID: 78651336430     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2010.530362     Document Type: Review
Times cited : (7)

References (104)
  • 3
    • 2942622200 scopus 로고    scopus 로고
    • Simple diagnostic assay for hairy cell leukaemia by immunocytochemical detection of annexin A1 (ANXA1)
    • Falini B, Tiacci E, Liso A, et al. Simple diagnostic assay for hairy cell leukaemia by immunocytochemical detection of annexin A1 (ANXA1). Lancet 2004;363:1869-1870.
    • (2004) Lancet , vol.363 , pp. 1869-1870
    • Falini, B.1    Tiacci, E.2    Liso, A.3
  • 4
    • 14344260649 scopus 로고    scopus 로고
    • Absence of surface CD27 distinguishes hairy cell leukemia from other leu-kemic B-cell malignancies
    • Forconi F, Raspadori D, Lenoci M, Lauria F. Absence of surface CD27 distinguishes hairy cell leukemia from other leu-kemic B-cell malignancies. Haematologica 2005;90:266-268.
    • (2005) Haematologica , vol.90 , pp. 266-268
    • Forconi, F.1    Raspadori, D.2    Lenoci, M.3    Lauria, F.4
  • 5
    • 0021690628 scopus 로고
    • Autopsy findings in hairy cell leukemia
    • Vardiman JW, Golomb HM. Autopsy findings in hairy cell leukemia. Semin Oncol 1984;11:370-380.
    • (1984) Semin Oncol , vol.11 , pp. 370-380
    • Vardiman, J.W.1    Golomb, H.M.2
  • 6
    • 0017233033 scopus 로고
    • The heterogeneity of leukemic reticuloendothe-liosis, 'hairy cell leukemia'. Evidence for its monocytic origin
    • Scheinberg M, Brenner AI, Sullivan AL, Cathcart ES, Katayama I. The heterogeneity of leukemic reticuloendothe-liosis, 'hairy cell leukemia'. Evidence for its monocytic origin. Cancer 1976;37:1302-1307.
    • (1976) Cancer , vol.37 , pp. 1302-1307
    • Scheinberg, M.1    Brenner, A.I.2    Sullivan, A.L.3    Cathcart, E.S.4    Katayama, I.5
  • 10
    • 0020598338 scopus 로고
    • Expression of an accessory cell phenotype by hairy cells during lymphocyte colony formation in agar culture
    • Farcet JP, Gourdin MF, Testa U, Andre C, Jouault H, Reyes F. Expression of an accessory cell phenotype by hairy cells during lymphocyte colony formation in agar culture. Leuk Res 1983;7:87-95.
    • (1983) Leuk Res , vol.7 , pp. 87-95
    • Farcet, J.P.1    Gourdin, M.F.2    Testa, U.3    Andre, C.4    Jouault, H.5    Reyes, F.6
  • 13
    • 0016347456 scopus 로고
    • Hairy cell leukemia: Proliferation of a cell with phagocytic and B-lymphocyte properties
    • Fu SM, Winchester RJ, Rai KR, Kunkel HG. Hairy cell leukemia: proliferation of a cell with phagocytic and B-lymphocyte properties. Scand J Immunol 1974;3:847-851.
    • (1974) Scand J Immunol , vol.3 , pp. 847-851
    • Fu, S.M.1    Winchester, R.J.2    Rai, K.R.3    Kunkel, H.G.4
  • 14
    • 0018128630 scopus 로고
    • Fc receptor bearing 'hairy cells' of leukaemic reticuloendotheliosis bind soluble antigen-antibody complexes and adhere to immobilized complexes, but fail to mediate antibody dependent cellular cytotoxicity
    • Alexander E, Sanders S. Fc receptor bearing 'hairy cells' of leukaemic reticuloendotheliosis bind soluble antigen-antibody complexes and adhere to immobilized complexes, but fail to mediate antibody dependent cellular cytotoxicity. Scand J Immunol 1978;8:477-488.
    • (1978) Scand J Immunol , vol.8 , pp. 477-488
    • Alexander, E.1    Sanders, S.2
  • 15
    • 0018141120 scopus 로고
    • Multiple heavy chain isotypes on the surface of the cells of hairy cell leukemia
    • Burns GF, Cawley JC, Worman CP, et al. Multiple heavy chain isotypes on the surface of the cells of hairy cell leukemia. Blood 1978;52:1132-1147.
    • (1978) Blood , vol.52 , pp. 1132-1147
    • Burns, G.F.1    Cawley, J.C.2    Worman, C.P.3
  • 16
    • 0018901551 scopus 로고
    • Surface immunoglobulin, lectin-induced cap formation, and phagocytic function in five patients with the leukemic phase of hairy cell leukemia
    • Golomb HM, Mintz U, Vardiman J, Wilson C, Rosner MC. Surface immunoglobulin, lectin-induced cap formation, and phagocytic function in five patients with the leukemic phase of hairy cell leukemia. Cancer 1980;46:50-55.
    • (1980) Cancer , vol.46 , pp. 50-55
    • Golomb, H.M.1    Mintz, U.2    Vardiman, J.3    Wilson, C.4    Rosner, M.C.5
  • 18
    • 0019969376 scopus 로고
    • Surface immunoglobulins on hairy cells of 55 patients with hairy cell leukemia
    • Golomb HM, Davis S, Wilson C, Vardiman J. Surface immunoglobulins on hairy cells of 55 patients with hairy cell leukemia. Am J Hematol 1982;12:397-401.
    • (1982) Am J Hematol , vol.12 , pp. 397-401
    • Golomb, H.M.1    Davis, S.2    Wilson, C.3    Vardiman, J.4
  • 19
    • 0020035434 scopus 로고
    • Alterations in the phenotype of hairy cells during culture in the presence of PHA: Requirement for T cells
    • Worman CP, Beverley PC, Cawley JC. Alterations in the phenotype of hairy cells during culture in the presence of PHA: requirement for T cells. Blood 1982;59:895-899.
    • (1982) Blood , vol.59 , pp. 895-899
    • Worman, C.P.1    Beverley, P.C.2    Cawley, J.C.3
  • 20
    • 0035883076 scopus 로고    scopus 로고
    • Tumor cells of hairy cell leukemia express multiple clonally related immunoglobulin isotypes via RNA splicing
    • Forconi F, Sahota SS, Raspadori D, Mockridge CI, Lauria F, Stevenson FK. Tumor cells of hairy cell leukemia express multiple clonally related immunoglobulin isotypes via RNA splicing. Blood 2001;98:1174-1181.
    • (2001) Blood , vol.98 , pp. 1174-1181
    • Forconi, F.1    Sahota, S.S.2    Raspadori, D.3    Mockridge, C.I.4    Lauria, F.5    Stevenson, F.K.6
  • 21
    • 0342281793 scopus 로고
    • Rearrangement and expression of immunoglobulin genes and expression of Tac antigen in hairy cell leukemia
    • Korsmeyer SJ, Greene WC, Cossman J, et al. Rearrangement and expression of immunoglobulin genes and expression of Tac antigen in hairy cell leukemia. Proc Natl Acad Sci USA 1983;80:4522-4526.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 4522-4526
    • Korsmeyer, S.J.1    Greene, W.C.2    Cossman, J.3
  • 23
    • 0346655210 scopus 로고    scopus 로고
    • Gene expression profiling of hairy cell leukemia reveals a phenotype related to memory B cells with altered expression of chemokine and adhesion receptors
    • Basso K, Liso A, Tiacci E, et al. Gene expression profiling of hairy cell leukemia reveals a phenotype related to memory B cells with altered expression of chemokine and adhesion receptors. J Exp Med 2004;199:59-68.
    • (2004) J Exp Med , vol.199 , pp. 59-68
    • Basso, K.1    Liso, A.2    Tiacci, E.3
  • 24
    • 6344291814 scopus 로고    scopus 로고
    • V(H) gene analysis of hairy cell leukemia reveals a homogeneous mutation status and suggests its marginal zone B-cell origin
    • Vanhentenrijk V, Tierens A, Wlodarska I, Verhoef G, Wolf-Peeters CD. V(H) gene analysis of hairy cell leukemia reveals a homogeneous mutation status and suggests its marginal zone B-cell origin. Leukemia 2004;18:1729-1732.
    • (2004) Leukemia , vol.18 , pp. 1729-1732
    • Vanhentenrijk, V.1    Tierens, A.2    Wlodarska, I.3    Verhoef, G.4    Wolf-Peeters, C.D.5
  • 25
    • 0035803464 scopus 로고    scopus 로고
    • Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells
    • Klein U, Tu Y, Stolovitzky GA, et al. Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells. J Exp Med 2001;194:1625-1638.
    • (2001) J Exp Med , vol.194 , pp. 1625-1638
    • Klein, U.1    Tu, Y.2    Stolovitzky, G.A.3
  • 26
    • 0032476611 scopus 로고    scopus 로고
    • Human immunoglobulin (Ig)MIgD peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells
    • Klein U, Rajewsky K, Kuppers R. Human immunoglobulin (Ig)MIgD peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells. J Exp Med 1998;188:1679-1689.
    • (1998) J Exp Med , vol.188 , pp. 1679-1689
    • Klein, U.1    Rajewsky, K.2    Kuppers, R.3
  • 27
    • 0141958337 scopus 로고    scopus 로고
    • Phenotype and genotype of interfollicular large B cells, a subpopulation of lymphocytes often with dendritic morphology
    • Marafioti T, Jones M, Facchetti F, et al. Phenotype and genotype of interfollicular large B cells, a subpopulation of lymphocytes often with dendritic morphology. Blood 2003;102:2868-2876.
    • (2003) Blood , vol.102 , pp. 2868-2876
    • Marafioti, T.1    Jones, M.2    Facchetti, F.3
  • 28
    • 70450260470 scopus 로고    scopus 로고
    • Defining origins of malignant B cells: A new circulating normal human IgM() D() B-cell subset lacking CD27 expression and displaying somatically mutated IGHV genes as a relevant memory population
    • Weston-Bell N, Townsend M, Di Genova G, Forconi F, Sahota SS. Defining origins of malignant B cells: a new circulating normal human IgM()D() B-cell subset lacking CD27 expression and displaying somatically mutated IGHV genes as a relevant memory population. Leukemia 2009;23:2075-2080.
    • (2009) Leukemia , vol.23 , pp. 2075-2080
    • Weston-Bell, N.1    Townsend, M.2    Di Genova, G.3    Forconi, F.4    Sahota, S.S.5
  • 29
    • 33748875713 scopus 로고    scopus 로고
    • B lymphocytes from early vertebrates have potent phagocytic and microbicidal abilities
    • Li J, Barreda DR, Zhang YA, et al. B lymphocytes from early vertebrates have potent phagocytic and microbicidal abilities. Nat Immunol 2006;7:1116-1124.
    • (2006) Nat Immunol , vol.7 , pp. 1116-1124
    • Li, J.1    Barreda, D.R.2    Zhang, Y.A.3
  • 30
    • 0019311564 scopus 로고
    • Phenotypic changes of phytohaemagglutinin-stimulated hairy cells
    • Guglielmi P, Preud'homme JL, Flandrin G. Phenotypic changes of phytohaemagglutinin-stimulated hairy cells. Nature 1980;286:166-168.
    • (1980) Nature , vol.286 , pp. 166-168
    • Guglielmi, P.1    Preud'Homme, J.L.2    Flandrin, G.3
  • 32
    • 0025243360 scopus 로고
    • Regulation of human B-cell ontogeny
    • Uckun FM. Regulation of human B-cell ontogeny. Blood 1990;76:1908-1923.
    • (1990) Blood , vol.76 , pp. 1908-1923
    • Uckun, F.M.1
  • 33
    • 0026844401 scopus 로고
    • The development of B cells and the B-cell repertoire in the microenvironment of the germinal center
    • Berek C. The development of B cells and the B-cell repertoire in the microenvironment of the germinal center. Immunol Rev 1992;126:5-19.
    • (1992) Immunol Rev , vol.126 , pp. 5-19
    • Berek, C.1
  • 35
    • 0036212917 scopus 로고    scopus 로고
    • Molecular mechanism of class switch recombination: Linkage with somatic hypermutation
    • Honjo T, Kinoshita K, Muramatsu M. Molecular mechanism of class switch recombination: linkage with somatic hypermutation. Annu Rev Immunol 2002;20:165-196.
    • (2002) Annu Rev Immunol , vol.20 , pp. 165-196
    • Honjo, T.1    Kinoshita, K.2    Muramatsu, M.3
  • 36
    • 0030460833 scopus 로고    scopus 로고
    • Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells
    • Han S, Zheng B, Schatz DG, Spanopoulou E, Kelsoe G. Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells. Science 1996;274:2094-2097.
    • (1996) Science , vol.274 , pp. 2094-2097
    • Han, S.1    Zheng, B.2    Schatz, D.G.3    Spanopoulou, E.4    Kelsoe, G.5
  • 37
    • 0031768520 scopus 로고    scopus 로고
    • Re-expression of RAG-1 and RAG-2 genes and evidence for secondary rearrangements in human germinal center B lymphocytes
    • Giachino C, Padovan E, Lanzavecchia A. Re-expression of RAG-1 and RAG-2 genes and evidence for secondary rearrangements in human germinal center B lymphocytes. Eur J Immunol 1998;28:3506-3513.
    • (1998) Eur J Immunol , vol.28 , pp. 3506-3513
    • Giachino, C.1    Padovan, E.2    Lanzavecchia, A.3
  • 38
    • 0035663555 scopus 로고    scopus 로고
    • Receptor revision plays no major role in shaping the receptor repertoire of human memory B cells after the onset of somatic hypermutation
    • Goossens T, Brauninger A, Klein U, Kuppers R, Rajewsky K. Receptor revision plays no major role in shaping the receptor repertoire of human memory B cells after the onset of somatic hypermutation. Eur J Immunol 2001;31:3638-3648.
    • (2001) Eur J Immunol , vol.31 , pp. 3638-3648
    • Goossens, T.1    Brauninger, A.2    Klein, U.3    Kuppers, R.4    Rajewsky, K.5
  • 40
    • 0033567907 scopus 로고    scopus 로고
    • Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
    • Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood 1999;94:1848-1854.
    • (1999) Blood , vol.94 , pp. 1848-1854
    • Hamblin, T.J.1    Davis, Z.2    Gardiner, A.3    Oscier, D.G.4    Stevenson, F.K.5
  • 41
    • 0141889260 scopus 로고    scopus 로고
    • VH mutation status and VDJ rearrangement structure in mantle cell lymphoma: Correlation with genomic aberrations, clinical characteristics, and outcome
    • Kienle D, Krober A, Katzenberger T, et al. VH mutation status and VDJ rearrangement structure in mantle cell lymphoma: correlation with genomic aberrations, clinical characteristics, and outcome. Blood 2003;102:3003-3009.
    • (2003) Blood , vol.102 , pp. 3003-3009
    • Kienle, D.1    Krober, A.2    Katzenberger, T.3
  • 42
    • 0022612915 scopus 로고
    • Biologic and prognostic significance of the presence of more than two mu heavy-chain genes in childhood acute lymphoblastic leukemia of B precursor cell origin
    • Kitchingman GR, Mirro J, Stass S, et al. Biologic and prognostic significance of the presence of more than two mu heavy-chain genes in childhood acute lymphoblastic leukemia of B precursor cell origin. Blood 1986;67:698-703.
    • (1986) Blood , vol.67 , pp. 698-703
    • Kitchingman, G.R.1    Mirro, J.2    Stass, S.3
  • 43
    • 0037103306 scopus 로고    scopus 로고
    • Typical Waldenstrom macroglobulinemia is derived from a B-cell arrested after cessation of somatic mutation but prior to isotype switch events
    • Sahota SS, Forconi F, Ottensmeier CH, et al. Typical Waldenstrom macroglobulinemia is derived from a B-cell arrested after cessation of somatic mutation but prior to isotype switch events. Blood 2002;100:1505-1507.
    • (2002) Blood , vol.100 , pp. 1505-1507
    • Sahota, S.S.1    Forconi, F.2    Ottensmeier, C.H.3
  • 44
    • 0033567968 scopus 로고    scopus 로고
    • Ig v gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia
    • Damle RN, Wasil T, Fais F, et al. Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood 1999;94:1840-1847.
    • (1999) Blood , vol.94 , pp. 1840-1847
    • Damle, R.N.1    Wasil, T.2    Fais, F.3
  • 45
    • 8644241022 scopus 로고    scopus 로고
    • Hairy cell leukemia: At the crossroad of somatic mutation and isotype switch
    • Forconi F, Sahota SS, Raspadori D, et al. Hairy cell leukemia: at the crossroad of somatic mutation and isotype switch. Blood 2004;104:3312-3317.
    • (2004) Blood , vol.104 , pp. 3312-3317
    • Forconi, F.1    Sahota, S.S.2    Raspadori, D.3
  • 46
    • 0000634555 scopus 로고
    • Developmentally restricted immunoglobulin heavy chain variable region gene expressed at high frequency in chronic lymphocytic leukemia
    • Kipps TJ, Tomhave E, Pratt LF, Duffy S, Chen PP, Carson DA. Developmentally restricted immunoglobulin heavy chain variable region gene expressed at high frequency in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 1989;86:5913-5917.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 5913-5917
    • Kipps, T.J.1    Tomhave, E.2    Pratt, L.F.3    Duffy, S.4    Chen, P.P.5    Carson, D.A.6
  • 47
    • 0030639650 scopus 로고    scopus 로고
    • Ig VH1 genes expressed in B cell chronic lymphocytic leukemia exhibit distinctive molecular features
    • Johnson TA, Rassenti LZ, Kipps TJ. Ig VH1 genes expressed in B cell chronic lymphocytic leukemia exhibit distinctive molecular features. J Immunol 1997;158:235-246.
    • (1997) J Immunol , vol.158 , pp. 235-246
    • Johnson, T.A.1    Rassenti, L.Z.2    Kipps, T.J.3
  • 48
    • 38949203770 scopus 로고    scopus 로고
    • Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: Implications for the role of antigen selection in leukemogenesis
    • Murray F, Darzentas N, Hadzidimitriou A, et al. Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: implications for the role of antigen selection in leukemogenesis. Blood 2008;111:1524-1533.
    • (2008) Blood , vol.111 , pp. 1524-1533
    • Murray, F.1    Darzentas, N.2    Hadzidimitriou, A.3
  • 49
    • 4944244255 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia B cells of more than 1% of patients express virtually identical immunoglobulins
    • Widhopf GF 2nd, Rassenti LZ, Toy TL, Gribben JG, Wierda WG, Kipps TJ. Chronic lymphocytic leukemia B cells of more than 1% of patients express virtually identical immunoglobulins. Blood 2004;104:2499-2504.
    • (2004) Blood , vol.104 , pp. 2499-2504
    • Widhopf, I.I.G.F.1    Rassenti, L.Z.2    Toy, T.L.3    Gribben, J.G.4    Wierda, W.G.5    Kipps, T.J.6
  • 50
    • 42449120194 scopus 로고    scopus 로고
    • Nonstochas-tic pairing of immunoglobulin heavy and light chains expressed by chronic lymphocytic leukemia B cells is predicated on the heavy chain CDR3
    • Widhopf GF 2nd, Goldberg CJ, Toy TL, et al. Nonstochas-tic pairing of immunoglobulin heavy and light chains expressed by chronic lymphocytic leukemia B cells is predicated on the heavy chain CDR3. Blood 2008;111: 3137-3144.
    • (2008) Blood , vol.111 , pp. 3137-3144
    • Widhopf, I.I.G.F.1    Goldberg, C.J.2    Toy, T.L.3
  • 51
    • 4344704897 scopus 로고    scopus 로고
    • Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia
    • Messmer BT, Albesiano E, Efremov DG, et al. Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia. J Exp Med 2004;200:519-525.
    • (2004) J Exp Med , vol.200 , pp. 519-525
    • Messmer, B.T.1    Albesiano, E.2    Efremov, D.G.3
  • 52
    • 33846108722 scopus 로고    scopus 로고
    • Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations
    • Stamatopoulos K, Belessi C, Moreno C, et al. Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: pathogenetic implications and clinical correlations. Blood 2007;109:259-270.
    • (2007) Blood , vol.109 , pp. 259-270
    • Stamatopoulos, K.1    Belessi, C.2    Moreno, C.3
  • 53
    • 74949107027 scopus 로고    scopus 로고
    • The normal IGHV1-69-derived B-cell repertoire contains stereotypic patterns characteristic of unmutated CLL
    • Forconi F, Potter KN, Wheatley I, et al. The normal IGHV1-69-derived B-cell repertoire contains stereotypic patterns characteristic of unmutated CLL. Blood 2010;115: 71-77.
    • (2010) Blood , vol.115 , pp. 71-77
    • Forconi, F.1    Potter, K.N.2    Wheatley, I.3
  • 54
    • 0031968134 scopus 로고    scopus 로고
    • VH gene expression in hairy cell leukaemia
    • Maloum K, Magnac C, Azgui Z, et al. VH gene expression in hairy cell leukaemia. Br J Haematol 1998;101:171-178.
    • (1998) Br J Haematol , vol.101 , pp. 171-178
    • Maloum, K.1    Magnac, C.2    Azgui, Z.3
  • 55
    • 33646229557 scopus 로고    scopus 로고
    • Somatic hypermutation and VH gene usage in hairy cell leukaemia
    • Arons E, Sunshine J, Suntum T, Kreitman RJ. Somatic hypermutation and VH gene usage in hairy cell leukaemia. Br J Haematol 2006;133:504-512.
    • (2006) Br J Haematol , vol.133 , pp. 504-512
    • Arons, E.1    Sunshine, J.2    Suntum, T.3    Kreitman, R.J.4
  • 56
    • 43449135924 scopus 로고    scopus 로고
    • Selective influences in the expressed immunoglobulin heavy and light chain gene repertoire in hairy cell leukemia
    • Forconi F, Sozzi E, Rossi D, et al. Selective influences in the expressed immunoglobulin heavy and light chain gene repertoire in hairy cell leukemia. Haematologica 2008;93: 697-705.
    • (2008) Haematologica , vol.93 , pp. 697-705
    • Forconi, F.1    Sozzi, E.2    Rossi, D.3
  • 57
    • 10644263109 scopus 로고    scopus 로고
    • Heterogeneous somatic hyper-mutation status confounds the cell of origin in hairy cell leukemia
    • Thorselius M, Walsh SH, Thunberg U, Hagberg H, Sundstrom C, Rosenquist R. Heterogeneous somatic hyper-mutation status confounds the cell of origin in hairy cell leukemia. Leuk Res 2005;29:153-158.
    • (2005) Leuk Res , vol.29 , pp. 153-158
    • Thorselius, M.1    Walsh, S.H.2    Thunberg, U.3    Hagberg, H.4    Sundstrom, C.5    Rosenquist, R.6
  • 58
    • 33745698839 scopus 로고    scopus 로고
    • Evolving concepts in the pathogenesis of hairy-cell leukaemia
    • Tiacci E, Liso A, Piris M, Falini B. Evolving concepts in the pathogenesis of hairy-cell leukaemia. Nat Rev Cancer 2006;6:437-448.
    • (2006) Nat Rev Cancer , vol.6 , pp. 437-448
    • Tiacci, E.1    Liso, A.2    Piris, M.3    Falini, B.4
  • 59
    • 73949121207 scopus 로고    scopus 로고
    • Hairy cell leukemias with unmutated IGHV genes define the minor subset refractory to single-agent cladribine and with more aggressive behavior
    • Forconi F, Sozzi E, Cencini E, et al. Hairy cell leukemias with unmutated IGHV genes define the minor subset refractory to single-agent cladribine and with more aggressive behavior. Blood 2009;114:4696-4702.
    • (2009) Blood , vol.114 , pp. 4696-4702
    • Forconi, F.1    Sozzi, E.2    Cencini, E.3
  • 60
    • 0027978252 scopus 로고
    • Aberrant rearrangements within the immunoglobulin heavy chain locus in hairy cell leukemia
    • Kayano H, Dyer MJ, Zani VJ, et al. Aberrant rearrangements within the immunoglobulin heavy chain locus in hairy cell leukemia. Leuk Lymphoma 1994;14(Suppl. 1):41-47.
    • (1994) Leuk Lymphoma , vol.14 , Issue.SUPPL. 1 , pp. 41-47
    • Kayano, H.1    Dyer, M.J.2    Zani, V.J.3
  • 61
    • 0025157694 scopus 로고
    • Hairy cell leukemia preferentially expresses the IgG3-subclass
    • Kluin-Nelemans HC, Krouwels MM, Jansen JH, et al. Hairy cell leukemia preferentially expresses the IgG3-subclass. Blood 1990;75:972-975.
    • (1990) Blood , vol.75 , pp. 972-975
    • Kluin-Nelemans, H.C.1    Krouwels, M.M.2    Jansen, J.H.3
  • 62
    • 0016189542 scopus 로고
    • Further evidence for the lymphocytic nature of leukaemic reticuloen-dotheliosis (hairy-cell leukaemia)
    • Haak HL, de Man JC, Hijmans W, Speck B. Further evidence for the lymphocytic nature of leukaemic reticuloen-dotheliosis (hairy-cell leukaemia). Br J Haematol 1974;27: 31-38.
    • (1974) Br J Haematol , vol.27 , pp. 31-38
    • Haak, H.L.1    De Man, J.C.2    Hijmans, W.3    Speck, B.4
  • 63
    • 0027247855 scopus 로고
    • Diagnostic application of two-color flow cytometry in 161 cases of hairy cell leukemia
    • Robbins BA, Ellison DJ, Spinosa JC, et al. Diagnostic application of two-color flow cytometry in 161 cases of hairy cell leukemia. Blood 1993;82:1277-1287.
    • (1993) Blood , vol.82 , pp. 1277-1287
    • Robbins, B.A.1    Ellison, D.J.2    Spinosa, J.C.3
  • 65
    • 0038293484 scopus 로고    scopus 로고
    • Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand
    • Ramiro AR, Stavropoulos P, Jankovic M, Nussenzweig MC. Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand. Nat Immunol 2003;4:452-456.
    • (2003) Nat Immunol , vol.4 , pp. 452-456
    • Ramiro, A.R.1    Stavropoulos, P.2    Jankovic, M.3    Nussenzweig, M.C.4
  • 66
    • 0034662773 scopus 로고    scopus 로고
    • Isolation, tissue distribution, and chromosomal localization of the human activation-induced cytidine deaminase (AID) gene
    • Muto T, Muramatsu M, Taniwaki M, Kinoshita K, Honjo T. Isolation, tissue distribution, and chromosomal localization of the human activation-induced cytidine deaminase (AID) gene. Genomics 2000;68:85-88.
    • (2000) Genomics , vol.68 , pp. 85-88
    • Muto, T.1    Muramatsu, M.2    Taniwaki, M.3    Kinoshita, K.4    Honjo, T.5
  • 67
    • 0037866404 scopus 로고    scopus 로고
    • Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomas
    • Greeve J, Philipsen A, Krause K, et al. Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomas. Blood 2003;101:3574-3580.
    • (2003) Blood , vol.101 , pp. 3574-3580
    • Greeve, J.1    Philipsen, A.2    Krause, K.3
  • 68
    • 0043175492 scopus 로고    scopus 로고
    • Expression of activation-induced cytidine deami-nase is confined to B-cell non-Hodgkin's lymphomas of germinal-center phenotype
    • Smit LA, Bende RJ, Aten J, Guikema JE, Aarts WM, van Noesel CJ. Expression of activation-induced cytidine deami-nase is confined to B-cell non-Hodgkin's lymphomas of germinal-center phenotype. Cancer Res 2003;63:3894-3898.
    • (2003) Cancer Res , vol.63 , pp. 3894-3898
    • Smit, L.A.1    Bende, R.J.2    Aten, J.3    Guikema, J.E.4    Aarts, W.M.5    Van Noesel, C.J.6
  • 69
    • 0030587822 scopus 로고    scopus 로고
    • Multiple types of chimeric germ-line Ig heavy chain transcripts in human B cells: Evidence for trans-splicing of human Ig RNA
    • Fujieda S, Lin YQ, Saxon A, Zhang K. Multiple types of chimeric germ-line Ig heavy chain transcripts in human B cells: evidence for trans-splicing of human Ig RNA. J Immunol 1996;157:3450-3459.
    • (1996) J Immunol , vol.157 , pp. 3450-3459
    • Fujieda, S.1    Lin, Y.Q.2    Saxon, A.3    Zhang, K.4
  • 70
    • 77953957633 scopus 로고    scopus 로고
    • A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
    • Poliseno L, Salmena L, Zhang J, Carver B, Haveman WJ, Pandolfi PP. A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature 2010;465:1033-1038.
    • (2010) Nature , vol.465 , pp. 1033-1038
    • Poliseno, L.1    Salmena, L.2    Zhang, J.3    Carver, B.4    Haveman, W.J.5    Pandolfi, P.P.6
  • 71
    • 78651312174 scopus 로고    scopus 로고
    • Lack of allelic exclusion by secondary rearrangements of tumour B-cell receptor light chains in hairy cell leukaemia
    • Jul 23. [ Epub ahead of print]
    • Sozzi E, Amato T, Sahota SS, et al. Lack of allelic exclusion by secondary rearrangements of tumour B-cell receptor light chains in hairy cell leukaemia. Hematol Oncol 2010 Jul 23. [Epub ahead of print]
    • (2010) Hematol Oncol
    • Sozzi, E.1    Amato, T.2    Sahota, S.S.3
  • 72
    • 43449135916 scopus 로고    scopus 로고
    • High density genome-wide DNA profiling reveals a remarkably stable profile in hairy cell leukaemia
    • Forconi F, Poretti G, Kwee I, et al. High density genome-wide DNA profiling reveals a remarkably stable profile in hairy cell leukaemia. Br J Haematol 2008;141:622-630.
    • (2008) Br J Haematol , vol.141 , pp. 622-630
    • Forconi, F.1    Poretti, G.2    Kwee, I.3
  • 73
    • 0025887102 scopus 로고
    • Duplicated variable region genes account for double isotype expression in a human leukemic B-cell line that gives rise to single isotype-expressing cells
    • Mizuta TR, Suzuki N, Shimizu A, Honjo T. Duplicated variable region genes account for double isotype expression in a human leukemic B-cell line that gives rise to single isotype-expressing cells. J Biol Chem 1991;266:12514-12521.
    • (1991) J Biol Chem , vol.266 , pp. 12514-12521
    • Mizuta, T.R.1    Suzuki, N.2    Shimizu, A.3    Honjo, T.4
  • 74
    • 0036933015 scopus 로고    scopus 로고
    • Do CLL B cells correspond to naive or memory B-lymphocytes? Evidence for an active Ig switch unrelated to phenotype expression and Ig mutational pattern in B-CLL cells
    • Oppezzo P, Magnac C, Bianchi S, et al. Do CLL B cells correspond to naive or memory B-lymphocytes? Evidence for an active Ig switch unrelated to phenotype expression and Ig mutational pattern in B-CLL cells. Leukemia 2002;16:2438-2446.
    • (2002) Leukemia , vol.16 , pp. 2438-2446
    • Oppezzo, P.1    Magnac, C.2    Bianchi, S.3
  • 75
    • 3543076504 scopus 로고    scopus 로고
    • Towards the pharmacotherapy of hairy cell leukaemia
    • Lauria F, Forconi F. Towards the pharmacotherapy of hairy cell leukaemia. Expert Opin Pharmacother 2004;5:1523-1533.
    • (2004) Expert Opin Pharmacother , vol.5 , pp. 1523-1533
    • Lauria, F.1    Forconi, F.2
  • 76
    • 0028016042 scopus 로고
    • The Scripps Clinic experience with 2-chlorodeoxyadenosine in the treatment of hairy cell leukemia
    • Piro LD, Ellison DJ, Saven A. The Scripps Clinic experience with 2-chlorodeoxyadenosine in the treatment of hairy cell leukemia. Leuk Lymphoma 1994;14(Suppl. 1):121-125. (Pubitemid 24282606)
    • (1994) Leukemia and Lymphoma , vol.14 , Issue.SUPPL. 1 , pp. 121-125
    • Piro, L.D.1    Ellison, D.J.2    Saven, A.3
  • 77
    • 0037362951 scopus 로고    scopus 로고
    • Extended follow-up of patients with hairy cell leukemia after treatment with cladribine
    • DOI 10.1200/JCO.2003.05.093
    • Goodman GR, Burian C, Koziol JA, Saven A. Extended follow-up of patients with hairy cell leukemia after treatment with cladribine. J Clin Oncol 2003;21:891-896. (Pubitemid 46606450)
    • (2003) Journal of Clinical Oncology , vol.21 , Issue.5 , pp. 891-896
    • Goodman, G.R.1    Burian, C.2    Koziol, J.A.3    Saven, A.4
  • 78
    • 66749169284 scopus 로고    scopus 로고
    • Long-term follow-up of 233 patients with hairy cell leukaemia, treated initially with pentostatin or cladribine, at a median of 16 years from diagnosis
    • Else M, Dearden CE, Matutes E, et al. Long-term follow-up of 233 patients with hairy cell leukaemia, treated initially with pentostatin or cladribine, at a median of 16 years from diagnosis. Br J Haematol 2009;145:733-740.
    • (2009) Br J Haematol , vol.145 , pp. 733-740
    • Else, M.1    Dearden, C.E.2    Matutes, E.3
  • 79
    • 70350148193 scopus 로고    scopus 로고
    • Recombinant immunotoxins for the treatment of chemoresistant hematologic malignancies
    • Kreitman RJ. Recombinant immunotoxins for the treatment of chemoresistant hematologic malignancies. Curr Pharm Des 2009;15:2652-2664.
    • (2009) Curr Pharm des , vol.15 , pp. 2652-2664
    • Kreitman, R.J.1
  • 80
    • 33745075957 scopus 로고    scopus 로고
    • Eradication of minimal residual disease in hairy cell leukemia
    • Ravandi F, Jorgensen JL, O'Brien SM, et al. Eradication of minimal residual disease in hairy cell leukemia. Blood 2006;107:4658-4662.
    • (2006) Blood , vol.107 , pp. 4658-4662
    • Ravandi, F.1    Jorgensen, J.L.2    O'Brien, S.M.3
  • 81
    • 67649933809 scopus 로고    scopus 로고
    • Phase II trial of recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) in patients with hairy cell leukemia
    • Kreitman RJ, Stetler-Stevenson M, Margulies I, et al. Phase II trial of recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) in patients with hairy cell leukemia. J Clin Oncol 2009;27:2983-2990.
    • (2009) J Clin Oncol , vol.27 , pp. 2983-2990
    • Kreitman, R.J.1    Stetler-Stevenson, M.2    Margulies, I.3
  • 82
    • 70449358325 scopus 로고    scopus 로고
    • Combination therapies to improve the long-term outcome in hairy cell leukemia
    • Lauria F, Forconi F. Combination therapies to improve the long-term outcome in hairy cell leukemia. Leuk Lymphoma 2009;50(Suppl. 1):18-22.
    • (2009) Leuk Lymphoma , vol.50 , Issue.SUPPL. 1 , pp. 18-22
    • Lauria, F.1    Forconi, F.2
  • 83
  • 84
    • 0028338450 scopus 로고
    • Flow cytometry of blood and bone marrow cells from patients with hairy cell leukemia: Phenotype of hairy cells and lymphocyte subsets after treatment with 2-chlorodeoxyadenosine
    • Juliusson G, Lenkei R, Liliemark J. Flow cytometry of blood and bone marrow cells from patients with hairy cell leukemia: phenotype of hairy cells and lymphocyte subsets after treatment with 2-chlorodeoxyadenosine. Blood 1994;83: 3672-3681.
    • (1994) Blood , vol.83 , pp. 3672-3681
    • Juliusson, G.1    Lenkei, R.2    Liliemark, J.3
  • 85
    • 0028219970 scopus 로고
    • 2-Chlorodeoxyadenosine: A newer purine analog active in the treatment of indolent lymphoid malignancies
    • Saven A, Piro LD. 2-Chlorodeoxyadenosine: a newer purine analog active in the treatment of indolent lymphoid malignancies. Ann Intern Med 1994;120:784-791.
    • (1994) Ann Intern Med , vol.120 , pp. 784-791
    • Saven, A.1    Piro, L.D.2
  • 86
    • 0042243678 scopus 로고    scopus 로고
    • Phase 2 study of rituximab in the treatment of cladribine-failed patients with hairy cell leukemia
    • DOI 10.1182/blood-2003-01-0014
    • Nieva J, Bethel K, Saven A. Phase 2 study of rituximab in the treatment of cladribine-failed patients with hairy cell leukemia. Blood 2003;102:810-813. (Pubitemid 36917768)
    • (2003) Blood , vol.102 , Issue.3 , pp. 810-813
    • Nieva, J.1    Bethel, K.2    Saven, A.3
  • 87
    • 2942738755 scopus 로고    scopus 로고
    • Long-term follow-up of front-line treatment of hairy cell leukemia with 2-chloro-deoxyadenosine
    • Zinzani PL, Tani M, Marchi E, et al. Long-term follow-up of front-line treatment of hairy cell leukemia with 2-chloro-deoxyadenosine. Haematologica 2004;89:309-313.
    • (2004) Haematologica , vol.89 , pp. 309-313
    • Zinzani, P.L.1    Tani, M.2    Marchi, E.3
  • 88
    • 28044446541 scopus 로고    scopus 로고
    • Long remissions in hairy cell leukemia with purine analogs: A report of 219 patients with a median follow-up of 12.5 years
    • Else M, Ruchlemer R, Osuji N, et al. Long remissions in hairy cell leukemia with purine analogs: a report of 219 patients with a median follow-up of 12.5 years. Cancer 2005;104:2442-2448.
    • (2005) Cancer , vol.104 , pp. 2442-2448
    • Else, M.1    Ruchlemer, R.2    Osuji, N.3
  • 89
    • 45149100665 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: A report from the International Workshop on Chronic Lympho-cytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines
    • Hallek M, Cheson BD, Catovsky D, et al. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lympho-cytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines. Blood 2008;111:5446-5456.
    • (2008) Blood , vol.111 , pp. 5446-5456
    • Hallek, M.1    Cheson, B.D.2    Catovsky, D.3
  • 90
    • 2942584865 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia: Revelations from the B-cell receptor
    • Stevenson FK, Caligaris-Cappio F. Chronic lymphocytic leukemia: revelations from the B-cell receptor. Blood 2004;103:4389-4395.
    • (2004) Blood , vol.103 , pp. 4389-4395
    • Stevenson, F.K.1    Caligaris-Cappio, F.2
  • 92
    • 0032844150 scopus 로고    scopus 로고
    • The effect of p53 dysfunction on purine analogue cytotoxicity in chronic lymphocytic leukaemia
    • Pettitt AR, Sherrington PD, Cawley JC. The effect of p53 dysfunction on purine analogue cytotoxicity in chronic lymphocytic leukaemia. Br J Haematol 1999;106:1049-1051.
    • (1999) Br J Haematol , vol.106 , pp. 1049-1051
    • Pettitt, A.R.1    Sherrington, P.D.2    Cawley, J.C.3
  • 93
    • 0027451668 scopus 로고
    • P53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe SW, Ruley HE, Jacks T, Housman DE. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 1993;74:957-967.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks Housman, T.D.E.3
  • 94
    • 54049141334 scopus 로고    scopus 로고
    • Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: Results from a detailed genetic characterization with long-term follow-up
    • Zenz T, Krober A, Scherer K, et al. Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: results from a detailed genetic characterization with long-term follow-up. Blood 2008;112: 3322-3329.
    • (2008) Blood , vol.112 , pp. 3322-3329
    • Zenz, T.1    Krober, A.2    Scherer, K.3
  • 95
    • 61549089361 scopus 로고    scopus 로고
    • The prognostic value of TP53 mutations in chronic lymphocytic leukemia is independent of del17p13: Implications for overall survival and chemorefractoriness
    • Rossi D, Cerri M, Deambrogi C, et al. The prognostic value of TP53 mutations in chronic lymphocytic leukemia is independent of del17p13: implications for overall survival and chemorefractoriness. Clin Cancer Res 2009;15:995-1004.
    • (2009) Clin Cancer Res , vol.15 , pp. 995-1004
    • Rossi, D.1    Cerri, M.2    Deambrogi, C.3
  • 96
    • 10744227172 scopus 로고    scopus 로고
    • A subset of t(11;14) lymphoma with mantle cell features displays mutated IgVH genes and includes patients with good prognosis, nonnodal disease
    • Orchard J, Garand R, Davis Z, et al. A subset of t(11;14) lymphoma with mantle cell features displays mutated IgVH genes and includes patients with good prognosis, nonnodal disease. Blood 2003;101:4975-4981.
    • (2003) Blood , vol.101 , pp. 4975-4981
    • Orchard, J.1    Garand, R.2    Davis, Z.3
  • 97
    • 0642281445 scopus 로고    scopus 로고
    • Binet's staging system and VH genes are independent but complementary prognostic indicators in chronic lymphocytic leukemia
    • Vasconcelos Y, Davi F, Levy V, et al. Binet's staging system and VH genes are independent but complementary prognostic indicators in chronic lymphocytic leukemia. J Clin Oncol 2003;21:3928-3932.
    • (2003) J Clin Oncol , vol.21 , pp. 3928-3932
    • Vasconcelos, Y.1    Davi, F.2    Levy, V.3
  • 98
    • 0037103212 scopus 로고    scopus 로고
    • V(H) mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukemia
    • Krober A, Seiler T, Benner A, et al. V(H) mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukemia. Blood 2002;100:1410-1416.
    • (2002) Blood , vol.100 , pp. 1410-1416
    • Krober, A.1    Seiler, T.2    Benner, A.3
  • 99
    • 73949120281 scopus 로고    scopus 로고
    • VH4-34 hairy cell leukemia, a new variant with poor prognosis despite standard therapy
    • Arons E, Suntum T, Stetler-Stevenson M, Kreitman RJ. VH4-34 hairy cell leukemia, a new variant with poor prognosis despite standard therapy. Blood 2009;114:4687-4695.
    • (2009) Blood , vol.114 , pp. 4687-4695
    • Arons, E.1    Suntum, T.2    Stetler-Stevenson, M.3    Kreitman, R.J.4
  • 100
    • 33748748650 scopus 로고    scopus 로고
    • Immunotoxins in the treatment of refractory hairy cell leukemia
    • viii
    • Kreitman RJ, Pastan I. Immunotoxins in the treatment of refractory hairy cell leukemia. Hematol Oncol Clin North Am 2006;20:1137-1151, viii.
    • (2006) Hematol Oncol Clin North Am , vol.20 , pp. 1137-1151
    • Kreitman, R.J.1    Pastan, I.2
  • 102
    • 0345689335 scopus 로고    scopus 로고
    • Rituximab in relapsed or refractory hairy cell leukemia
    • Thomas DA, O'Brien S, Bueso-Ramos C, et al. Rituximab in relapsed or refractory hairy cell leukemia. Blood 2003;102:3906-3911.
    • (2003) Blood , vol.102 , pp. 3906-3911
    • Thomas, D.A.1    O'Brien, S.2    Bueso-Ramos, C.3
  • 103
    • 36048956034 scopus 로고    scopus 로고
    • The role of rituximab in combination with pentostatin or cladribine for the treatment of recurrent/refractory hairy cell leukemia
    • Else M, Osuji N, Forconi F, et al. The role of rituximab in combination with pentostatin or cladribine for the treatment of recurrent/refractory hairy cell leukemia. Cancer 2007;110:2240-2247.
    • (2007) Cancer , vol.110 , pp. 2240-2247
    • Else, M.1    Osuji, N.2    Forconi, F.3
  • 104
    • 37149031235 scopus 로고    scopus 로고
    • Complete molecular remission induced by concomitant cladribine-rituximab treatment in a case of multi-resistant hairy cell leukemia
    • Forconi F, Toraldo F, Sozzi E, Amato T, Raspadori D, Lauria F. Complete molecular remission induced by concomitant cladribine-rituximab treatment in a case of multi-resistant hairy cell leukemia. Leuk Lymphoma 2007; 48:2441-2443.
    • (2007) Leuk Lymphoma , vol.48 , pp. 2441-2443
    • Forconi, F.1    Toraldo, F.2    Sozzi, E.3    Amato, T.4    Raspadori, D.5    Lauria, F.6


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