Typical waldenstrom macroglobulinemia is derived from a B-cell arrested after cessation of somatic mutation but prior to isotype switch events

Blood

Volumn 100, Issue 4, 2002, Pages 1505-1507

  Sahota, Surinder S ^a,b,c   Forconi, Francesco ^a,b,c   Ottensmeier, Christian H ^a,b,c   Provan, Drew ^a,b,c   Oscier, David G ^a,b,c   Hamblin, Terry J ^a,b,c   Stevenson, Freda K ^a,b,c  

^a UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c ROYAL BOURNEMOUTH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN M;

ARTICLE; B LYMPHOCYTE; CLINICAL ARTICLE; CLONAL VARIATION; GENE MUTATION; GENETIC TRANSFORMATION; GERMINAL CENTER; HUMAN; HUMAN CELL; MACROGLOBULINEMIA; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SOMATIC MUTATION; WALDENSTROEM MACROGLOBULINEMIA;

EID: 0037103306     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v100.4.1505.h81602001505_1505_1507     Document Type: Article

References (24)

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20. Ongoing Ig gene hypermutation in salivary gland mucosa-associated lymphoid tissue-type lymphomas
21. Analysis of immunoglobulin genes in splenic marginal zone lymphoma suggests ongoing mutation
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23. Memory B lymphocytes migrate to bone marrow in humans