P2X7 receptors mediate deleterious renal epithelial-fibroblast cross talk

American Journal of Physiology - Renal Physiology

Volumn 300, Issue 1, 2011, Pages

  Ponnusamy, Murugavel ^a   Ma, Li ^a   Gong, Rujun ^a   Pang, Maoyin ^a   Chin, Y Eugene ^a   Zhuang, Shougang ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

Acute kidney injury; Renal proximal tubular cells

Indexed keywords

APYRASE; PURINERGIC P2X7 RECEPTOR; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; A 438079; A-438079; ADENOSINE TRIPHOSPHATE; DIAGNOSTIC AGENT; PURINERGIC P2X RECEPTOR ANTAGONIST; PYRIDINE DERIVATIVE; TETRAZOLE DERIVATIVE; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL DEATH; CELL LYSATE; CONTROLLED STUDY; FIBROBLAST; KIDNEY EPITHELIUM; NONHUMAN; PRIORITY JOURNAL; RAT; ACUTE KIDNEY FAILURE; ANIMAL; APOPTOSIS; CELL CULTURE; COCULTURE; CYTOLOGY; DRUG EFFECT; KIDNEY; KIDNEY PROXIMAL TUBULE; NECROSIS; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ACUTE KIDNEY INJURY; ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; CELLS, CULTURED; COCULTURE TECHNIQUES; FIBROBLASTS; KIDNEY; KIDNEY TUBULES, PROXIMAL; NECROSIS; PURINERGIC P2X RECEPTOR ANTAGONISTS; PYRIDINES; RATS; RECEPTORS, PURINERGIC P2X7; SIGNAL TRANSDUCTION; TETRAZOLES; TETRAZOLIUM SALTS; THIAZOLES;

EID: 78651271783     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00473.2010     Document Type: Article

References (44)

1. Bachmann S, Le Hir M, Eckardt KU. Co-localization of erythropoietin mRNA, and ecto-5′-nucleotidase immunoreactivity in peritubular cells of rat renal cortex indicates that fibroblasts produce erythropoietin. J Histochem Cytochem, 41: 335-341, 1993.
2. Baud L, Ardaillou R. Tumor necrosis factor in renal injury. Miner Electrolyte Metab 21: 336-341, 1995.
3. Bonegio R, Lieberthal W. Role of apoptosis in the pathogenesis of acute renal failure. Curr Opin Nephrol Hypertens 11: 301-308, 2002. (Pubitemid 34496778)
4. Cao H, Mattison J, Zhao Y, Joki N, Grasso M, Chang NS. Regulation of tumor necrosis factor-and Fas-mediated apoptotic cell death by a novel cDNA TR2L. Biochem Biophys Res Commun 227: 266-272, 1996.
5. Casiano CA, Ochs RI, Tan EM. Distinct cleavage products of nuclear proteins in apoptosis, and necrosis revealed by autoantibody probes. Cell Death Differ 5: 183-190, 1998.
6. Chakfe Y, Seguin R, Antel JP, Morissette C, Malo D, Henderson D, Seguela P. ADP and AMP induce interleukin-1beta release from microglial cells through activation of ATP-primed P2X7 receptor channels. J Neurosci 22: 3061-3069, 2002.
7. Coutinho-Silva R, Persechini PM, Bisaggio RD, Perfettini JL, Neto AC, Kanellopoulos JM, Motta-Ly I, Dautry-Varsat A, Ojcius DM. P2Z/P2X7 receptor-dependent apoptosis of dendritic cells. Am J Physiol Cell Physiol 276: C1139-C1147, 1999.
8. Cummings BS, Schnellmann RG. Cisplatin-induced renal cell apoptosis: caspase 3-dependent and -independent pathways. J Pharmacol Exp Ther 302: 8-17, 2002.
9. Di Virgilio F. ATP as a death factor. Biofactors 8: 301-303, 1998.
10. Du C, Jiang J, Guan Q, Yin Z, Masterson M, Parbtani A, Zhong R, Jevnikar AM. Renal tubular epithelial cell self-injury through Fas/Fas ligand interaction promotes renal allograft injury. Am J Transplant 4: 1583-1594, 2004.
11. Duan S, Neary JT. P2X7 receptors: properties and relevance to CNS function. Glia 54: 738-46, 2006.
12. Eckardt KU. Erythropoietin production in liver and kidneys. Curr Opin Nephrol Hypertens 5: 28-34, 1996.
13. Estrov Z, Thall PF, Talpaz M, Estey EH, Kantarjian HM, Andreeff M, Harris D, Van Q, Walterscheid M, Kornblau SM. Caspase 2 and caspase 3 protein levels as predictors of survival in acute myelogenous leukemia. Blood 92: 3090-3097, 1998.
14. Evans RJ, Lewis C, Buell G, Valera S, North RA, Surprenant A. Pharmacological characterization of heterologously expressed ATP-gated cation channels (P2x purinoceptors). Mol Pharmacol 48: 178-183, 1995.
15. Gobeil S, Boucher CC, Nadeau D, Poirier GG. Characterization of the necrotic cleavage of poly(ADP-ribose) polymerase (P.A.R.P.-1): implication of lysosomal proteases. Cell Death Differ 8: 588-594, 2001.
16. Harada H, Chan CM, Loesch A, Unwin R, Burnstock G. Induction of proliferation, and apoptotic cell death via P.2Y and P2X receptors, respectively, in rat glomerular mesangial cells. Kidney Int 57: 949-958, 2000.
17. Hillman KA, Burnstock G, Unwin RJ. The P2X7 ATP receptor in the kidney: a matter of life or death? Nephron Exp Nephrol 101: e24-e30, 2005. (Pubitemid 41159948)
18. Hillman KA, Woolf AS, Johnson TM, Wade A, Unwin RJ, Winyard PJ. The P2X7 ATP receptor modulates renal cyst development in vitro. Biochem Biophys Res Commun 322: 434-439, 2004.
19. Jacobson KA, Costanzi S, Joshi BV, Besada P, Shin DH, Ko H, Ivanov AA, Mamedova L. Agonists and antagonists for P2 receptors. Novartis Found Symp 276: 58-68, 2006.
20. Jankowski V, Karadogan S, Vanholder R, Nofer JR, Herget- Rosenthal S, van der Giet M, Tolle M, Tran TN, Zidek W, Jankowski J. Paracrine stimulation of vascular smooth muscle proliferation by diadenosine polyphosphates released from proximal tubule epithelial cells. Kidney Int 71: 994-1000, 2007.
21. Jenkins DA, Wojtacha DR, Swan P, Fleming S, Cumming AD. Intrarenal localization of interleukin-1 beta mRNA in crescentic glomerulonephritis. Nephrol Dial Transplant 9: 1228-1233, 1994.
22. Johnson DW, Pat B, Vesey DA, Guan Z, Endre Z, Gobe GC. Delayed administration of darbepoetin or erythropoietin protects against ischemic acute renal injury, and failure. Kidney Int 69: 1806-1813, 2006.
23. Kaissling B, Le Hir M. The renal cortical interstitium: morphological, and functional aspects. Histochem Cell Biol 130: 247-262, 2008.
24. Koide N, Narita K, Kato Y, Sugiyama T, Chakravortty D, Morikawa A, Yoshida T, Yokochi T. Expression of Fas, and Fas ligand on mouse renal tubular epithelial cells in the generalized Shwartzman reaction and its relationship to apoptosis. Infect Immun 67: 4112-4118, 1999.
25. Le Feuvre RA, Brough D, Iwakura Y, Takeda K, Rothwell NJ. Priming of macrophages with lipopolysaccharide potentiates P2X7-mediated cell death via a caspase-1-dependent mechanism, independently of cytokine production. J Biol Chem 277: 3210-3218, 2002.
26. Maxwell PH, Ferguson DJ, Nicholls LG, Johnson MH, Ratcliffe PJ. The interstitial response to renal injury: fibroblast-like cells show phenotypic changes, and have reduced potential for erythropoietin gene expression. Kidney Int 52: 715-724, 1997.
27. Mene P, Polci R, Festuccia F. Mechanisms of repair after kidney injury. J Nephrol 16: 186-195, 2003.
28. Narcisse L, Scemes E, Zhao Y, Lee SC, Brosnan CF. The cytokine IL1beta transiently enhances P2X7 receptor expression, and function in human astrocytes. Glia 49: 245-258, 2005.
29. Nelson DW, Gregg RJ, Kort ME, Perez-Medrano A, Voight EA, Wang Y, Grayson G, Namovic MT, Donnelly-Roberts DL, Niforatos W, Honore P, Jarvis MF, Faltynek CR, Carroll WA. Structure-activity relationship studies on a series of novel substituted 1-benzyl-5-phenyltetrazole P2X7 antagonists. J Med Chem 49: 3659-3666, 2006. (Pubitemid 43902471)
30. North RA. Molecular physiology of P2X receptors. Physiol Rev 82: 1013-1067, 2002.
31. Padanilam BJ. Cell death induced by acute renal injury: a perspective on the contributions of apoptosis and necrosis. Am J Physiol Renal Physiol 284: F608-F627, 2003.
32. Peng W, Cotrina ML, Han X, Yu H, Bekar L, Blum L, Takano T, Tian GF, Goldman SA, Nedergaard M. Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury. Proc Natl Acad Sci USA 106: 12489-12493, 2009.
33. Ramesh G, Brian Reeves W. Cisplatin increases TNFalpha mRNA stability in kidney proximal tubule cells. Ren Fail 28: 583-592, 2006.
34. Schulze-Lohoff E, Hugo C, Rost S, Arnold S, Gruber A, Brune B, Sterzel RB. Extracellular ATP causes apoptosis, and necrosis of cultured mesangial cells via P2Z/P2X7 receptors. Am J Physiol Renal Physiol 275: F962-F971, 1998.
35. Shah GM, Shah RG, Poirier GG. Different cleavage pattern for poly-(ADP-ribose) polymerase during necrosis, and apoptosis in HL-60 cells. Biochem Biophys Res Commun 229: 838-844, 1996.
36. Sharples EJ, Patel N, Brown P, Stewart K, Mota-Philipe H, Sheaff M, Kieswich J, Allen D, Harwood S, Raftery M, Thiemermann C, Yaqoob MM. Erythropoietin protects the kidney against the injury, and dysfunction caused by ischemia-reperfusion. J Am Soc Nephrol 15: 2115-2124, 2004. (Pubitemid 39031350)
37. Skaper SD, Debetto P, Giusti P. The P2X7 purinergic receptor: from physiology to neurological disorders. FASEB J 24: 337-345, 2009.
38. Spandou E, Tsouchnikas I, Karkavelas G, Dounousi E, Simeonidou C, Guiba-Tziampiri O, Tsakiris D. Erythropoietin attenuates renal injury in experimental acute renal failure ischaemic/reperfusion model. Nephrol Dial Transplant 21: 330-336, 2006.
39. --secreting epithelia and 3T3 fibroblasts. J Biol Chem 269: 17853-17857, 1994.
40. Taylor SR, Turner CM, Elliott JI, McDaid J, Hewitt R, Smith J, Pickering MC, Whitehouse DL, Cook HT, Burnstock G, Pusey CD, Unwin RJ, Tam FW. P2X7 deficiency attenuates renal injury in experimental glomerulonephritis. J Am Soc Nephrol 20: 1275-1281, 2009.
41. Turner CM, Elliott JI, Tam FW. P2 receptors in renal pathophysiology. Purinergic Signal 5: 513-520, 2009.
42. Tuttolomondo A, Di Sciacca R, Di Raimondo D, Renda C, Pinto A, Licata G. Inflammation as a therapeutic target in acute ischemic stroke treatment. Curr Top Med Chem 9: 1240-1260, 2009.
43. Vonend O, Turner CM, Chan CM, Loesch A, Dell'Anna GC, Srai KS, Burnstock G, Unwin RJ. Glomerular expression of the ATP-sensitive P2X receptor in diabetic and hypertensive rat models. Kidney Int 66: 157-166, 2004.
44. Zhuang S, Lu B, Daubert RA, Chavin KD, Wang L, Schnellmann RG. Suramin promotes recovery from renal ischemia/reperfusion injury in mice. Kidney Int 75: 304-311, 2009.