Paracrine stimulation of vascular smooth muscle proliferation by diadenosine polyphosphates released from proximal tubule epithelial cells

Kidney International

Volumn 71, Issue 10, 2007, Pages 994-1000

  Jankowski, V ^a   Karadogan, S ^a   Vanholder, R ^b   Nofer, J R ^c   Herget Rosenthal, S ^d   Van Der Giet, M ^a   Tolle M ^a   Tran, T N A ^a   Zidek, W ^a   Jankowski, J ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b GHENT UNIVERSITY HOSPITAL   (Belgium)

^c UNIVERSITY OF MÜNSTER   (Germany)

^d UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Diadenosine; Polyphosphates; Proliferation; Tubular cell

Indexed keywords

DIADENOSINE HEXAPHOSPHATE; DIADENOSINE PENTAPHOSPHATE; DIADENOSINE POLYPHOSPHATE; PLATELET DERIVED GROWTH FACTOR; PURINE P2X RECEPTOR; PURINE P2Y RECEPTOR; SURAMIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CLONE; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; KIDNEY TUBULE EPITHELIUM; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; THORACIC AORTA; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA, THORACIC; CELL PROLIFERATION; CELLS, CULTURED; DINUCLEOSIDE PHOSPHATES; DRUG SYNERGISM; EPITHELIAL CELLS; KIDNEY TUBULES, PROXIMAL; MALE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PARACRINE COMMUNICATION; PLATELET-DERIVED GROWTH FACTOR; RATS; RATS, INBRED WKY; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SWINE;

EID: 34248403648     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/sj.ki.5002186     Document Type: Article

References (41)

1. Inscho EW, Cook AK, Imig JD et al. Physiological role for P2X1 receptors in renal microvascular autoregulatory behavior. J Clin Invest 2003; 112: 1895-1905.
2. Leipziger J. Control of epithelial transport via luminal P2 receptors. Am J Physiol Renal Physiol 2003; 284: F419-F432.
3. Schwiebert EM, Kishore BK. Extracellular nucleotide signaling along the renal epithelium. Am J Physiol Renal Physiol 2001; 280: F945-F963.
4. Cuffe JE, Bielfeld-Ackermann A, Thomas J et al. ATP stimulates Cl- secretion and reduces amiloride-sensitive Na+ absorption in M-1 mouse cortical collecting duct cells. J Physiol 2000; 524(Part 1): 77-90.
5. 2+ signaling. Am J Physiol 1996; 270: F53-F60.
6. Brindikova TA, Bourcier N, Torres B et al. Purinergic-induced signaling in C11-MDCK cells inhibits the secretory Na-K-Cl cotransporter. Am J Physiol Cell Physiol 2003; 285: C1445-C1453.
7. Kishore BK, Chou CL, Knepper MA. Extracellular nucleotide receptor inhibits AVP-stimulated water permeability in inner medullary collecting duct. Am J Physiol 1995; 269: F863-F869.
8. Lu M, MacGregor GG, Wang W et al. Extracellular ATP inhibits the small-conductance K channel on the apical membrane of the cortical collecting duct from mouse kidney. J Gen Physiol 2000; 116: 299-310.
9. Taylor AL, Kudlow BA, Marrs KL et al. Bioluminescence detection of ATP release mechanisms in epithelia. Am J Physiol 1998; 275: C1391-C1406.
10. Hoyle CHV, Hilderman RH, Pintor JJ et al. Diadenosine polyphosphates as extracellular signal molecules. Drug Dev Res 2001; 52: 260-273.
11. 5A in human plasma. Eur J Clin Invest 1998; 28: 12.
12. 4A) as an endothelium-derived vasoconstrictive factor. Nat Med 2005; 11: 223-227.
13. Jankowski J, Jankowski V, Laufer U et al. Identification and quantification of diadenosine polyphosphate concentrations in human plasma. Arterioscler Thromb Vasc Biol 2003; 23: 1231-1238.
14. 7-diadenosine-5′- heptaphosphate from human platelets. J Biol Chem 1999; 274: 23926-23931.
15. Flodgaard H, Klenow H. Abundant amounts of diadenosine 5′,5‴-P1,P4-tetraphosphate are present and releasable, but metabolically inactive, in human platelets. Biochem J 1982; 208: 737-742.
16. 2G in releasable granlues of platelets. J Biol Chem 2001; 276: 8904-8909.
17. Pintor J, Rotllan P, Torres M et al. Characterization and quantification of diadenosine hexaphosphate in chromaffin cells. granular storage and secretagogue-induced release. Anal Biochem 1992; 200: 296-300.
18. Castillo CJ, Moro MA, Del Valle M et al. Diadenosine tetraphosphate is co-released with ATP and catecholamines from bovine adrenal medulla. J Neurochem 1992; 59: 723-732.
19. Jankowski J, Jankowski V, Seibt B et al. Identification of dinucleoside polyphosphates in adrenal glands. Biochem Biophys Res Commun 2003; 304: 365-370.
20. Luo J, Jankowski V, Gungar N et al. Endogenous diadenosine tetraphosphate, diadenosine pentaphosphate, and diadenosine hexaphosphate in human myocardial tissue. Hypertension 2004; 43: 1055-1059.
21. Zimmermann H, Volknandt W, Wittich B et al. Synaptic vesicle life cycle and synaptic turnover. J Physiol Paris 1993; 87: 159-170.
22. van der Giet M, Jankowski J, Schlüter H et al. Mediation of the vasoactive properties of diadenosine tetraphosphate via various purinoceptors. J Hypertens 1998; 16: 1939-1943.
23. van der Giet M, Schmidt S, Tölle M et al. Effects of dinucleoside polyphosphates on regulation of coronary vascular tone. Eur J Pharmacol 2002; 448: 207-213.
24. Heidenreich S, Tepel M, Schlüter H et al. Regulation of rat mesangial cell growth by diadenosine phosphates. J Clin Invest 1995; 95: 2862-2867.
25. Jankowski J, Hagemann J, Yoon MS et al. Increased vascular growth in hemodialysis patients induced by platelet-derived diadenosine polyphosphates. Kidney Int 2001; 59: 1134-1141.
26. McLennan AG. Dinucleoside polyphosphates-friend or foe? Pharmacol Ther 2000; 87: 73-89.
27. Pintor J, Miras-Portugal MT. P2 purinergic receptors for diadenosine polyphosphates in the nervous system. Gen Pharmacol 1995; 26: 229-235.
28. Westfall TD, McIntyre CA, Obeid S et al. The interaction of diadenosine polyphosphates with P2x-receptors in the guinea-pig isolated vas deferens. Br J Pharmacol 1997; 121: 57-62.
29. Bailey MA, Hillman KA, Unwin RJ. P2 receptors in the kidney. J Auton Nerv Syst 2000; 81: 264-270.
30. 4A) and nicotinamide adenine dinucleotide (NAD) in rat. J Physiol Pharmacol 2003; 54: 163-173.
31. Burnstock G. Purinergic signaling and vascular cell proliferation and death. Arterioscler Thromb Vasc Biol 2002; 22: 364-373.
32. 4A in human plasma. Purification and characterization of a glycoprotein complex with 5′-nucleotide phosphodiesterase activity. Eur J Biochem 1985; 149: 119-127.
33. Jankowski J, Grosse-Huettmann P, Zidek W et al. Identification of dinucleoside polyphosphates by matrix-assisted laser desorption/ionisation post-source decay mass spectrometry. Rapid Commun Mass Spectrom 2003; 17: 1189-1194.
34. Franks DJ, Plamondon J, Hamet P. An increase in adenylate cyclase activity precedes DNA synthesis in cultured vascular smooth muscle cells. J Cell Physiol 1984; 119: 41-45.
35. Ross R. The smooth muscle cell. II. Growth of smooth muscle in culture and formation of elastic fibers. J Cell Biol 1971; 50: 172-186.
36. Bendhack LM, Sharma RV, Bhalla RC. Altered signal transduction in vascular smooth muscle cells of spontaneously hypertensive rats. Hypertension 1992; 19: II142-II148.
37. Bean BP. Pharmacology and electrophysiology of ATP-activated ion channels. Trends Pharmacol Sci 1992; 13: 87-90.
38. Fedan JS, Lamport SJ. P2-purinoceptor antagonists. Ann NY Acad Sci 1990; 603: 182-196.
39. Heidenreich S, Gong JH, Schmidt A et al. Macrophage activation by granulocyte/macrophage colony-stimulating factor. Priming for enhanced release of tumor necrosis factor-alpha and prostaglandin E2. J Immunol 1989; 143: 1198-1205.
40. Jankowski J, Stephan N, Knobloch M et al. Mass-spectrometry-linked screening of protein fractions for enzymatic activities-a tool for functional genomics. Anal Biochem 2001; 290: 324-329.
41. Kribben A, Feldkamp T, Horbelt M et al. ATP protects, by way of receptor-mediated mechanisms, against hypoxia-induced injury in renal proximal tubules. J Lab Clin Med 2003; 141: 67-73.