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It should be, however, noted that solvent-free exothermic reactions can be problematic because a thermal buffer is missing. For a related study, see
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It should be, however, noted that solvent-free exothermic reactions can be problematic because a thermal buffer is missing. For a related study, see: L. Balland N. Mouhab J.-M. Cosmao L. Estel Chem. Eng. Proc. 2002 41 395.
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For other copper-catalysed N-heteroarylations of nitrogen nucleophiles with heteroaryl halides, see
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The MW experiments, the temperature was measured by an internal thermocouple. The setting power of the MW instrument was 50 W during the entire reaction time. When the temperature reached 100 °C, the instrument automatically adjusted the power to maintain this temperature
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In the MW experiments, the temperature was measured by an internal thermocouple. The setting power of the MW instrument was 50 W during the entire reaction time. When the temperature reached 100 °C, the instrument automatically adjusted the power to maintain this temperature.
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60
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62649152953
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For recent mechanistic studies on copper-catalysed cross-couplings, see
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Sulfoximines have been found to be effective chiral ligands in several catalytic asymmetric reactions by our group. For recent examples, see
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Sulfoximines have been found to be effective chiral ligands in several catalytic asymmetric reactions by our group. For recent examples, see: M. Frings I. Atodiresei J. Runsink G. Raabe C. Bolm Chem. Eur. J. 2009 15 1566.
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3, 100 °C, MW (50 W), 1 h] can also be applied in the coupling between phenyl iodide and S-methyl-S-phenylsulfoximine to give the corresponding N-arylated product in 72% yield
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3, 100 °C, MW (50 W), 1 h] can also be applied in the coupling between phenyl iodide and S-methyl-S-phenylsulfoximine to give the corresponding N-arylated product in 72% yield.
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