Mapping dynamic histone acetylation patterns to gene expression in nanog-depleted murine embryonic stem cells

PLoS Computational Biology

Volumn 6, Issue 12, 2010, Pages

  Markowetz, Florian ^a,b   Mulder, Klaas W ^a   Airoldi, Edoardo M ^c   Lemischka, Ihor R ^d   Troyanskaya, Olga G ^e  

^a CANCER RESEARCH UK CAMBRIDGE RESEARCH INSTITUTE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c HARVARD UNIVERSITY   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e Princeton University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL GROWTH; GENE EXPRESSION REGULATION; STEM CELLS; TRANSCRIPTION;

EMBRYONIC STEM CELLS; GENES EXPRESSION; HISTONE ACETYLATION; LINEAGE SPECIFICATION; MAPPING DYNAMICS; MOLECULAR MECHANISM; MURINE EMBRYONIC STEM CELLS; PLURIPOTENCY; SELF RENEWAL; STEM-CELL;

ACETYLATION;

HISTONE H3; MESSENGER RNA; TRANSCRIPTION FACTOR NANOG; HISTONE; HOMEODOMAIN PROTEIN; NANOG PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL FATE; CELL RENEWAL; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE LOCATION; GENE MAPPING; GENE REGULATORY NETWORK; GENE SILENCING; GENETIC ASSOCIATION; GENETIC GAIN; GENETIC SELECTION; HISTONE ACETYLATION; LOSS OF FUNCTION MUTATION; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; ONLINE ANALYSIS; PREDICTION; PROTEIN DEPLETION; RNA INTERFERENCE; STATISTICAL ANALYSIS; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION; VALIDATION PROCESS; ACETYLATION; ANIMAL; BIOLOGY; CHEMISTRY; CLUSTER ANALYSIS; GENETICS; METABOLISM; METHODOLOGY; PHENOTYPE;

MURINAE;

ACETYLATION; ANIMALS; CLUSTER ANALYSIS; COMPUTATIONAL BIOLOGY; EMBRYONIC STEM CELLS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE SILENCING; GENOME-WIDE ASSOCIATION STUDY; HISTONES; HOMEODOMAIN PROTEINS; MICE; PHENOTYPE;

EID: 78651251562     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1001034     Document Type: Article

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