-
1
-
-
37849001772
-
Electrostatic contributions of aromatic residues in the local anesthetic receptor of voltage-gated sodium channels
-
Ahern C., Eastwood A.L., Dougherty D.A., Horn R. Electrostatic contributions of aromatic residues in the local anesthetic receptor of voltage-gated sodium channels. Circ. Res. 2008, 102:86-94.
-
(2008)
Circ. Res.
, vol.102
, pp. 86-94
-
-
Ahern, C.1
Eastwood, A.L.2
Dougherty, D.A.3
Horn, R.4
-
2
-
-
0025263891
-
Molecular mechanisms of local anesthesia: a review
-
Butterworth J.F., Strichartz G.R. Molecular mechanisms of local anesthesia: a review. Anesthesiology 1990, 72:711-734.
-
(1990)
Anesthesiology
, vol.72
, pp. 711-734
-
-
Butterworth, J.F.1
Strichartz, G.R.2
-
3
-
-
0023574096
-
Common modes of drug action of Na+ channels: local anesthetics, antiarrhythmics, and anticonvulsants
-
Catterall W.A. Common modes of drug action of Na+ channels: local anesthetics, antiarrhythmics, and anticonvulsants. Trends Pharmacol. Sci. 1987, 8:57-65.
-
(1987)
Trends Pharmacol. Sci.
, vol.8
, pp. 57-65
-
-
Catterall, W.A.1
-
4
-
-
0033694833
-
From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels
-
Catterall W.A. From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels. Neuron 2000, 26:13-25.
-
(2000)
Neuron
, vol.26
, pp. 13-25
-
-
Catterall, W.A.1
-
5
-
-
0029091192
-
Cloning and functional analysis of TipE, a novel membrane protein that enhances Drosophila para sodium channel function
-
Feng G., Deak P., Chopra M., Hall L.M. Cloning and functional analysis of TipE, a novel membrane protein that enhances Drosophila para sodium channel function. Cell 1995, 82:1001-1011.
-
(1995)
Cell
, vol.82
, pp. 1001-1011
-
-
Feng, G.1
Deak, P.2
Chopra, M.3
Hall, L.M.4
-
6
-
-
28844499151
-
A mutation in the local anaesthetic binding site abolishes toluene effects in sodium channels
-
Gauthereau M.Y., Salinas-Stefanon E.M., Cruz S.L. A mutation in the local anaesthetic binding site abolishes toluene effects in sodium channels. Eur. J. Pharmacol. 2005, 528:17-26.
-
(2005)
Eur. J. Pharmacol.
, vol.528
, pp. 17-26
-
-
Gauthereau, M.Y.1
Salinas-Stefanon, E.M.2
Cruz, S.L.3
-
7
-
-
0035050571
-
Resurgence of sodium channel research
-
Goldin A.L. Resurgence of sodium channel research. Annu. Rev. Physiol. 2001, 63:871-894.
-
(2001)
Annu. Rev. Physiol.
, vol.63
, pp. 871-894
-
-
Goldin, A.L.1
-
8
-
-
0017332486
-
Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction
-
Hille B. Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction. J. Gen. Physiol. 1977, 69:497-515.
-
(1977)
J. Gen. Physiol.
, vol.69
, pp. 497-515
-
-
Hille, B.1
-
9
-
-
0021287507
-
Antiarrhythmic agents: the modulated receptor mechanism of action of sodium and calcium channel-blocking drugs
-
Hondeghem L.M., Katzung B.G. Antiarrhythmic agents: the modulated receptor mechanism of action of sodium and calcium channel-blocking drugs. Annu. Rev. Pharmacol. Toxicol. 1984, 24:387-423.
-
(1984)
Annu. Rev. Pharmacol. Toxicol.
, vol.24
, pp. 387-423
-
-
Hondeghem, L.M.1
Katzung, B.G.2
-
10
-
-
0035129476
-
Indoxacarb, an oxadiazine insecticide, blocks insect neuronal sodium channels
-
Lapied B., Grolleau F., Sattelle D.B. Indoxacarb, an oxadiazine insecticide, blocks insect neuronal sodium channels. Br. J. Pharmacol. 2001, 132:587-595.
-
(2001)
Br. J. Pharmacol.
, vol.132
, pp. 587-595
-
-
Lapied, B.1
Grolleau, F.2
Sattelle, D.B.3
-
11
-
-
0032919699
-
A molecular basis for the different local anesthetic affinities of resting versus open and inactivated states of the sodium channel
-
Li H.-L., Galue A., Meadows L., Ragsdale D.S. A molecular basis for the different local anesthetic affinities of resting versus open and inactivated states of the sodium channel. Mol. Pharmacol. 1999, 55:134-141.
-
(1999)
Mol. Pharmacol.
, vol.55
, pp. 134-141
-
-
Li, H.-L.1
Galue, A.2
Meadows, L.3
Ragsdale, D.S.4
-
12
-
-
0037373028
-
Differential interactions of lamotrigine and related drugs with transmembrane segment IVS6 of voltage-gated sodium channels
-
Liu G., Yarov-Yarovoy V., Nobbs M., Clare J.J., Scheuer T., Catterall W.A. Differential interactions of lamotrigine and related drugs with transmembrane segment IVS6 of voltage-gated sodium channels. Neuropharmacology 2003, 44:413-422.
-
(2003)
Neuropharmacology
, vol.44
, pp. 413-422
-
-
Liu, G.1
Yarov-Yarovoy, V.2
Nobbs, M.3
Clare, J.J.4
Scheuer, T.5
Catterall, W.A.6
-
13
-
-
0032794137
-
Point mutations at N434 in D1-S6 of μ1 Na+ channels modulate binding affinity and stereoselectivity of local anesthetic enantiomers
-
Nau C., Wang S.-Y., Strichartz G.R., Wang G.K. Point mutations at N434 in D1-S6 of μ1 Na+ channels modulate binding affinity and stereoselectivity of local anesthetic enantiomers. Mol. Pharmacol. 1999, 56:404-413.
-
(1999)
Mol. Pharmacol.
, vol.56
, pp. 404-413
-
-
Nau, C.1
Wang, S.-Y.2
Strichartz, G.R.3
Wang, G.K.4
-
14
-
-
0038102242
-
Point mutations at L1280 in Nav 1.4 channel D3-S6 modulate binding affinity and stereoselectivity of bupivacaine enantiomers
-
Nau C., Wang S.-Y., Wang G.K. Point mutations at L1280 in Nav 1.4 channel D3-S6 modulate binding affinity and stereoselectivity of bupivacaine enantiomers. Mol. Pharmacol. 2003, 63:1398-1406.
-
(2003)
Mol. Pharmacol.
, vol.63
, pp. 1398-1406
-
-
Nau, C.1
Wang, S.-Y.2
Wang, G.K.3
-
15
-
-
0032545731
-
Effects of bisaramil, a novel class I antiarrhythmic agent, on heart, skeletal muscle and brain Na channels
-
Pugsley M.K., Goldin A.L. Effects of bisaramil, a novel class I antiarrhythmic agent, on heart, skeletal muscle and brain Na channels. Eur. J. Pharmacol 1998, 342:93-104.
-
(1998)
Eur. J. Pharmacol
, vol.342
, pp. 93-104
-
-
Pugsley, M.K.1
Goldin, A.L.2
-
16
-
-
0027944683
-
Molecular determinants of state-dependent block of Na+ channels by local anesthetics
-
Ragsdale D.S., McPhee J.C., Scheuer T., Catterall W.A. Molecular determinants of state-dependent block of Na+ channels by local anesthetics. Science 1994, 265:1724-1728.
-
(1994)
Science
, vol.265
, pp. 1724-1728
-
-
Ragsdale, D.S.1
McPhee, J.C.2
Scheuer, T.3
Catterall, W.A.4
-
17
-
-
0029787945
-
Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels
-
Ragsdale D.S., McPhee J.C., Scheuer T., Catterall W.A. Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels. Proc. Natl. Acad. Sci. 1996, 93:9270-9275.
-
(1996)
Proc. Natl. Acad. Sci.
, vol.93
, pp. 9270-9275
-
-
Ragsdale, D.S.1
McPhee, J.C.2
Scheuer, T.3
Catterall, W.A.4
-
18
-
-
0026551929
-
Slow voltage-dependent block of sodium channels in crayfish nerve by dihydropyrazole insecticides
-
Salgado V.L. Slow voltage-dependent block of sodium channels in crayfish nerve by dihydropyrazole insecticides. Mol. Pharmacol. 1992, 41:120-126.
-
(1992)
Mol. Pharmacol.
, vol.41
, pp. 120-126
-
-
Salgado, V.L.1
-
19
-
-
36049001733
-
Metaflumizone is a novel sodium channel blocker insecticide
-
Salgado V.L., Hayashi J.H. Metaflumizone is a novel sodium channel blocker insecticide. Vet. Parasitol. 2007, 150:182-189.
-
(2007)
Vet. Parasitol.
, vol.150
, pp. 182-189
-
-
Salgado, V.L.1
Hayashi, J.H.2
-
20
-
-
67650995976
-
Role of the sixth segment of domain IV of the cockroach sodium channel in the action of sodium channel-blocker insecticides
-
Silver K., Nomura Y., Salgado V.L., Dong K. Role of the sixth segment of domain IV of the cockroach sodium channel in the action of sodium channel-blocker insecticides. Neurotoxicology 2009, 30:613-621.
-
(2009)
Neurotoxicology
, vol.30
, pp. 613-621
-
-
Silver, K.1
Nomura, Y.2
Salgado, V.L.3
Dong, K.4
-
21
-
-
20344367986
-
State-dependent block of rat Nav1.4 sodium channels expressed in Xenopus oocytes by pyrazoline-type insecticides
-
Silver K., Soderlund D.M. State-dependent block of rat Nav1.4 sodium channels expressed in Xenopus oocytes by pyrazoline-type insecticides. Neurotoxicology 2005, 26:397-406.
-
(2005)
Neurotoxicology
, vol.26
, pp. 397-406
-
-
Silver, K.1
Soderlund, D.M.2
-
22
-
-
34249727760
-
Point mutations at the local anesthetic receptor site modulate the state-dependent block of rat Nav1.4 sodium channels by pyrazoline-type insecticides
-
Silver K., Soderlund D.M. Point mutations at the local anesthetic receptor site modulate the state-dependent block of rat Nav1.4 sodium channels by pyrazoline-type insecticides. Neurotoxicology 2007, 28:655-663.
-
(2007)
Neurotoxicology
, vol.28
, pp. 655-663
-
-
Silver, K.1
Soderlund, D.M.2
-
23
-
-
67650995976
-
The role of the sixth transmembrane segment of domain IV of the cockroach sodium channel in the action of sodium channel blocker insecticides
-
Silver K., Song W., Nomura Y., Salgado V.L., Dong K. The role of the sixth transmembrane segment of domain IV of the cockroach sodium channel in the action of sodium channel blocker insecticides. Neurotoxicology 2009, 30:613-621.
-
(2009)
Neurotoxicology
, vol.30
, pp. 613-621
-
-
Silver, K.1
Song, W.2
Nomura, Y.3
Salgado, V.L.4
Dong, K.5
-
24
-
-
32244440290
-
Molecular basis of differential sensitivity of insect sodium channels to DCJW, a bioactive metabolite of the oxadiazine insecticide indoxacarb
-
Song W.Z., Liu Z.Q., Dong K. Molecular basis of differential sensitivity of insect sodium channels to DCJW, a bioactive metabolite of the oxadiazine insecticide indoxacarb. Neurotoxicology 2006, 27:237-244.
-
(2006)
Neurotoxicology
, vol.27
, pp. 237-244
-
-
Song, W.Z.1
Liu, Z.Q.2
Dong, K.3
-
25
-
-
0036663011
-
Alternative splicing of an insect sodium channel gene generates pharmacologically distinct sodium channels
-
Tan J., Liu Z., Nomura Y., Goldin A.L., Dong K. Alternative splicing of an insect sodium channel gene generates pharmacologically distinct sodium channels. J. Neurosci. 2002, 22:5300-5309.
-
(2002)
J. Neurosci.
, vol.22
, pp. 5300-5309
-
-
Tan, J.1
Liu, Z.2
Nomura, Y.3
Goldin, A.L.4
Dong, K.5
-
26
-
-
0027930074
-
Differential mechanism of action of the pyrethroid tetramethrin on tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels
-
Tatebayashi H., Narahashi T. Differential mechanism of action of the pyrethroid tetramethrin on tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels. J. Pharmacol. Exp. Ther. 1994, 270:595-603.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.270
, pp. 595-603
-
-
Tatebayashi, H.1
Narahashi, T.2
-
27
-
-
3242668020
-
State-dependent block of voltage-gated Na+ channels by amitriptyline via the local anesthetic receptor and its implication for neuropathic pain
-
Wang G.K., Russell C., Wang S.-Y. State-dependent block of voltage-gated Na+ channels by amitriptyline via the local anesthetic receptor and its implication for neuropathic pain. Pain 2004, 110:166-174.
-
(2004)
Pain
, vol.110
, pp. 166-174
-
-
Wang, G.K.1
Russell, C.2
Wang, S.-Y.3
-
28
-
-
0033849987
-
Residues in Na+ channel D3-S6 segment modulate batrachotoxin and local anesthetic affinities
-
Wang S.-Y., Nau C., Wang G.K. Residues in Na+ channel D3-S6 segment modulate batrachotoxin and local anesthetic affinities. Biophys. J. 2000, 79:1379-1387.
-
(2000)
Biophys. J.
, vol.79
, pp. 1379-1387
-
-
Wang, S.-Y.1
Nau, C.2
Wang, G.K.3
-
29
-
-
13144262837
-
Point mutations in segment I-S6 render voltage-gated Na+ channels resistant to batrachotoxin
-
Wang S.-Y., Wang G.K. Point mutations in segment I-S6 render voltage-gated Na+ channels resistant to batrachotoxin. Proc. Natl. Acad. Sci. 1998, 95:2653-2658.
-
(1998)
Proc. Natl. Acad. Sci.
, vol.95
, pp. 2653-2658
-
-
Wang, S.-Y.1
Wang, G.K.2
-
30
-
-
0037290637
-
Voltage-gated sodium channels as primary targets of diverse lipid-soluble neurotoxins
-
Wang S.-Y., Wang G.K. Voltage-gated sodium channels as primary targets of diverse lipid-soluble neurotoxins. Cell. Signal. 2003, 15:151-159.
-
(2003)
Cell. Signal.
, vol.15
, pp. 151-159
-
-
Wang, S.-Y.1
Wang, G.K.2
-
31
-
-
15444351062
-
Functional expression of Drosophila para sodium channels: modulation by the membrane protein tipE and toxin pharmacology
-
Warmke J.W., Reenan R.A.G., Wang P., Qian S., Arena J.P., Wang J., Wunderler D., Liu K., Kaczorowski G.J., Van Der Ploeg L.H.T., Ganetzky B., Cohen C.J. Functional expression of Drosophila para sodium channels: modulation by the membrane protein tipE and toxin pharmacology. J. Gen. Physiol. 1997, 110:119-133.
-
(1997)
J. Gen. Physiol.
, vol.110
, pp. 119-133
-
-
Warmke, J.W.1
Reenan, R.A.G.2
Wang, P.3
Qian, S.4
Arena, J.P.5
Wang, J.6
Wunderler, D.7
Liu, K.8
Kaczorowski, G.J.9
Van Der Ploeg, L.H.T.10
Ganetzky, B.11
Cohen, C.J.12
-
32
-
-
0032746327
-
Differential interaction of R-mexiletine with the local anesthetic receptor site on brain and heart sodium channel α-subunits
-
Weiser T., Qu Y., Catterall W.A., Scheuer T. Differential interaction of R-mexiletine with the local anesthetic receptor site on brain and heart sodium channel α-subunits. Mol. Pharmacol. 1999, 56:1238-1244.
-
(1999)
Mol. Pharmacol.
, vol.56
, pp. 1238-1244
-
-
Weiser, T.1
Qu, Y.2
Catterall, W.A.3
Scheuer, T.4
-
33
-
-
85069939105
-
Indoxacarb and the sodium channel blocker insecticides: chemistry, physiology, and biology in insects
-
Elsevier, New York, L.I. Gilbert, K. Iatrou, S.S. Gill (Eds.)
-
Wing K.D., Andaloro J.T., McCann S.F., Salgado V.L. Indoxacarb and the sodium channel blocker insecticides: chemistry, physiology, and biology in insects. Comprehensive Molecular Insect Science 2005, vol. 6:30-53. Elsevier, New York. L.I. Gilbert, K. Iatrou, S.S. Gill (Eds.).
-
(2005)
Comprehensive Molecular Insect Science
, vol.6
, pp. 30-53
-
-
Wing, K.D.1
Andaloro, J.T.2
McCann, S.F.3
Salgado, V.L.4
-
34
-
-
0033738259
-
Bioactivation and mode of action of the oxadiazine indoxacarb in insects
-
Wing K.D., Sacher M., Kagaya Y., Tsurubuchi Y., Mulderig L., Connair M., Schnee M.E. Bioactivation and mode of action of the oxadiazine indoxacarb in insects. Crop Prot. 2000, 19:537-545.
-
(2000)
Crop Prot.
, vol.19
, pp. 537-545
-
-
Wing, K.D.1
Sacher, M.2
Kagaya, Y.3
Tsurubuchi, Y.4
Mulderig, L.5
Connair, M.6
Schnee, M.E.7
-
35
-
-
0002763061
-
A novel oxadiazine insecticide is bioactivated in lepidopteran larvae
-
Wing K.D., Schnee M.E., Sacher M., Connair M. A novel oxadiazine insecticide is bioactivated in lepidopteran larvae. Arch. Insect Biochem. Physiol. 1998, 37:91-103.
-
(1998)
Arch. Insect Biochem. Physiol.
, vol.37
, pp. 91-103
-
-
Wing, K.D.1
Schnee, M.E.2
Sacher, M.3
Connair, M.4
-
36
-
-
0031725974
-
Lysine point mutations in Na+ channel D4-S6 reduce inactivated channel block by local anesthetics
-
Wright S.N., Wang S.-Y., Wang G.K. Lysine point mutations in Na+ channel D4-S6 reduce inactivated channel block by local anesthetics. Mol. Pharmacol. 1998, 54:733-739.
-
(1998)
Mol. Pharmacol.
, vol.54
, pp. 733-739
-
-
Wright, S.N.1
Wang, S.-Y.2
Wang, G.K.3
-
37
-
-
0035808309
-
Molecular determinants of voltage-dependent gating and binding of pore-blocking drugs in transmembrane segment IIIS6 of the Na+ channel α subunit
-
Yarov-Yarovoy V., Brown J., Sharp E., Clare J.J., Scheuer T., Catterall W.A. Molecular determinants of voltage-dependent gating and binding of pore-blocking drugs in transmembrane segment IIIS6 of the Na+ channel α subunit. J. Biol. Chem. 2001, 276:20-27.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20-27
-
-
Yarov-Yarovoy, V.1
Brown, J.2
Sharp, E.3
Clare, J.J.4
Scheuer, T.5
Catterall, W.A.6
-
38
-
-
0037144493
-
Role of amino acid residues in transmembrane segments IS6 and IIS6 of the Na+ channel α subunit in voltage-dependent gating and drug block
-
Yarov-Yarovoy V., McPhee J.C., Idsvoog D., Pate C., Scheuer T., Catterall W.A. Role of amino acid residues in transmembrane segments IS6 and IIS6 of the Na+ channel α subunit in voltage-dependent gating and drug block. J. Biol. Chem. 2002, 277:35393-35401.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 35393-35401
-
-
Yarov-Yarovoy, V.1
McPhee, J.C.2
Idsvoog, D.3
Pate, C.4
Scheuer, T.5
Catterall, W.A.6
-
39
-
-
20344375439
-
Block of two subtypes of sodium channels in cockroach neurons by indoxacarb insecticides
-
Zhao X., Ikeda T., Salgado V.L., Yeh J.Z., Narahashi T. Block of two subtypes of sodium channels in cockroach neurons by indoxacarb insecticides. Neurotoxicology 2005, 26:455-465.
-
(2005)
Neurotoxicology
, vol.26
, pp. 455-465
-
-
Zhao, X.1
Ikeda, T.2
Salgado, V.L.3
Yeh, J.Z.4
Narahashi, T.5
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