-
2
-
-
1542619848
-
Cancer as a robust system: implications for anticancer therapy
-
Kitano H. Cancer as a robust system: implications for anticancer therapy. Nat Rev Cancer 2004, 4:227-235.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 227-235
-
-
Kitano, H.1
-
3
-
-
61849135453
-
Tumor suppressors and cell metabolism: a recipe for cancer growth
-
Jones R.G., Thompson C.B. Tumor suppressors and cell metabolism: a recipe for cancer growth. Genes Dev 2009, 23:537-548.
-
(2009)
Genes Dev
, vol.23
, pp. 537-548
-
-
Jones, R.G.1
Thompson, C.B.2
-
4
-
-
69949124867
-
Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells
-
Feron O. Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells. Rad Oncol 2009, 92:329-333.
-
(2009)
Rad Oncol
, vol.92
, pp. 329-333
-
-
Feron, O.1
-
5
-
-
67449155921
-
A new target for tumor therapy
-
Jain K.J. A new target for tumor therapy. New Eng J Med 2009, 360:2669-2671.
-
(2009)
New Eng J Med
, vol.360
, pp. 2669-2671
-
-
Jain, K.J.1
-
6
-
-
69949095183
-
Blood flow metabolism mismatch: good for the tumor, bad for the patient
-
Mankoff D.A., et al. Blood flow metabolism mismatch: good for the tumor, bad for the patient. Clin Cancer Res 2009, 15:5294-5296.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5294-5296
-
-
Mankoff, D.A.1
-
7
-
-
3142587028
-
Tumor microenvironmental physiology and its implications for radiation oncology
-
Vaupel P. Tumor microenvironmental physiology and its implications for radiation oncology. Sem Rad Oncol 2004, 14:198-206.
-
(2004)
Sem Rad Oncol
, vol.14
, pp. 198-206
-
-
Vaupel, P.1
-
8
-
-
84960987950
-
The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy
-
Gray L.H., et al. The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy. Br J Radiolog 1953, 26:638-648.
-
(1953)
Br J Radiolog
, vol.26
, pp. 638-648
-
-
Gray, L.H.1
-
10
-
-
0030614893
-
Interstitial pH and PO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation
-
Helmlinger G. Interstitial pH and PO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation. Nat Med 1997, 3:177-182.
-
(1997)
Nat Med
, vol.3
, pp. 177-182
-
-
Helmlinger, G.1
-
11
-
-
44449147036
-
Tumor cell metabolism: cancer's Achilles' heel
-
Kroemer G., Pouyssegur J. Tumor cell metabolism: cancer's Achilles' heel. Cancer Cell 2008, 13:472-482.
-
(2008)
Cancer Cell
, vol.13
, pp. 472-482
-
-
Kroemer, G.1
Pouyssegur, J.2
-
12
-
-
33847367741
-
Energy metabolism in tumor cells
-
Moreno-Sánchez R., Rodríguez-Enríquez S., Marin-Hernández A., Saavedra E. Energy metabolism in tumor cells. FEBS J 2007, 274:1393-1418.
-
(2007)
FEBS J
, vol.274
, pp. 1393-1418
-
-
Moreno-Sánchez, R.1
Rodríguez-Enríquez, S.2
Marin-Hernández, A.3
Saavedra, E.4
-
13
-
-
27744502691
-
Targeting energy metabolism in brain cancer: review and hypothesis
-
Seyfried T.N., Mukherjee P. Targeting energy metabolism in brain cancer: review and hypothesis. Nutr Metab 2005, 2:30.
-
(2005)
Nutr Metab
, vol.2
, pp. 30
-
-
Seyfried, T.N.1
Mukherjee, P.2
-
15
-
-
69949109921
-
Decreased blood flow with increased metabolic activity: a novel sign of pancreatic tumor aggressiveness
-
Komar G., et al. Decreased blood flow with increased metabolic activity: a novel sign of pancreatic tumor aggressiveness. Clin Cancer Res 2009, 15:5511-5517.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5511-5517
-
-
Komar, G.1
-
16
-
-
47249089233
-
A rational approach to the systemic treatment of cancer involving medium-term depletion of arginine
-
Wheatley D.N., Campbell E., Lai P.B.S., Cheng P.N.M. A rational approach to the systemic treatment of cancer involving medium-term depletion of arginine. Gene Ther Mol Biol 2005, 9:33-40.
-
(2005)
Gene Ther Mol Biol
, vol.9
, pp. 33-40
-
-
Wheatley, D.N.1
Campbell, E.2
Lai, P.B.S.3
Cheng, P.N.M.4
-
17
-
-
0025335785
-
Intraoperative spillage of tumor cells in surgery for rectal cancer
-
Zirngibl H., Husemann B., Hermanek P. Intraoperative spillage of tumor cells in surgery for rectal cancer. Dis Colon Rectum 2005, 33:610-614.
-
(2005)
Dis Colon Rectum
, vol.33
, pp. 610-614
-
-
Zirngibl, H.1
Husemann, B.2
Hermanek, P.3
-
18
-
-
0038481970
-
The pathogenesis of cancer metastasis: the 'seed' and 'soil' hypothesis revisited
-
Fidler I.J. The pathogenesis of cancer metastasis: the 'seed' and 'soil' hypothesis revisited. Nat Rev Cancer 2003, 3:1-6.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 1-6
-
-
Fidler, I.J.1
-
20
-
-
0032570704
-
Glucose deprivation-induced cytoxicity and alterations in mitogen-activated protein kinase activation are mediated by oxidative stress in multidrug-resistant human breast carcinoma cells
-
Lee J.L., et al. Glucose deprivation-induced cytoxicity and alterations in mitogen-activated protein kinase activation are mediated by oxidative stress in multidrug-resistant human breast carcinoma cells. J Biol Chem 1997, 273:5294-5299.
-
(1997)
J Biol Chem
, vol.273
, pp. 5294-5299
-
-
Lee, J.L.1
-
21
-
-
0037093411
-
Contribution by different fuels and metabolic pathways to the total ATP turnover of proliferating MCF-7 breast cancer cells
-
Guppy M., Leedman P., Zu X., Russell V. Contribution by different fuels and metabolic pathways to the total ATP turnover of proliferating MCF-7 breast cancer cells. Biochem J 2002, 364:309-315.
-
(2002)
Biochem J
, vol.364
, pp. 309-315
-
-
Guppy, M.1
Leedman, P.2
Zu, X.3
Russell, V.4
-
22
-
-
78651078719
-
Effect of extracellular AMP on cell proliferation and metabolism of breast cancer cell lines with high and low glycolytic rates
-
Mazurek S., Michel A., Eigenbrodt E. Effect of extracellular AMP on cell proliferation and metabolism of breast cancer cell lines with high and low glycolytic rates. J Biol Chem 1997, 57:159-164.
-
(1997)
J Biol Chem
, vol.57
, pp. 159-164
-
-
Mazurek, S.1
Michel, A.2
Eigenbrodt, E.3
-
23
-
-
0347694776
-
Cancer metabolism: facts, fantasy, and fiction
-
Zu X.L., Guppy M. Cancer metabolism: facts, fantasy, and fiction. Biochem Biophys Res Commun 2004, 313:459-465.
-
(2004)
Biochem Biophys Res Commun
, vol.313
, pp. 459-465
-
-
Zu, X.L.1
Guppy, M.2
-
24
-
-
0034652620
-
High lactate levels predict likelihood of metastasis, tumor recurrence, and restricted patient survival in human cervical cancers
-
Walenta S., et al. High lactate levels predict likelihood of metastasis, tumor recurrence, and restricted patient survival in human cervical cancers. Cancer Res 2000, 60:916-921.
-
(2000)
Cancer Res
, vol.60
, pp. 916-921
-
-
Walenta, S.1
-
25
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell 2000, 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
26
-
-
37449024702
-
The biology of cancer: metabolic reprogramming that fuels growth and proliferation
-
DeBerardinis R.J., Lum J.J., Hatzivassiliou G., Thompson C.B. The biology of cancer: metabolic reprogramming that fuels growth and proliferation. Cell Metab 2000, 7:11-20.
-
(2000)
Cell Metab
, vol.7
, pp. 11-20
-
-
DeBerardinis, R.J.1
Lum, J.J.2
Hatzivassiliou, G.3
Thompson, C.B.4
-
27
-
-
33749478922
-
Cancer's molecular sweet tooth and the Warburg effect
-
Kim J.W., Dang C.V. Cancer's molecular sweet tooth and the Warburg effect. Cancer Res 2006, 66:8927-8930.
-
(2006)
Cancer Res
, vol.66
, pp. 8927-8930
-
-
Kim, J.W.1
Dang, C.V.2
-
28
-
-
12444279265
-
On the origin of cancer cells
-
Warburg O. On the origin of cancer cells. Science 1956, 23:309-314.
-
(1956)
Science
, vol.23
, pp. 309-314
-
-
Warburg, O.1
-
29
-
-
66249108601
-
Understanding the Warburg effect: the metabolic requirements of cell proliferation
-
Vander Heiden M.G., Cantley L.C., Thompson C.B. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009, 324:1029-1033.
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
30
-
-
34748912615
-
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
-
Menendez J.A., Lupu R. Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis. Nat Rev Cancer 2007, 7:763-777.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 763-777
-
-
Menendez, J.A.1
Lupu, R.2
-
31
-
-
0033079597
-
Oncogenic alterations of metabolism
-
Chi V.D., Semenza G.L. Oncogenic alterations of metabolism. TIBS 1999, 24:68-72.
-
(1999)
TIBS
, vol.24
, pp. 68-72
-
-
Chi, V.D.1
Semenza, G.L.2
-
32
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
Gatenby R.A., Gillies R.J. Why do cancers have high aerobic glycolysis?. Nat Rev Cancer 2004, 4:891-899.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
33
-
-
0033079597
-
Oncogenic alterations of metabolism
-
Dang C.V., Semenza G.L. Oncogenic alterations of metabolism. TIBS 1999, 24:68-72.
-
(1999)
TIBS
, vol.24
, pp. 68-72
-
-
Dang, C.V.1
Semenza, G.L.2
-
34
-
-
33750619348
-
Glucose metabolism and cancer
-
Shaw R.J. Glucose metabolism and cancer. Curr Opin Cell Biol 2006, 18:598-608.
-
(2006)
Curr Opin Cell Biol
, vol.18
, pp. 598-608
-
-
Shaw, R.J.1
-
35
-
-
33744969828
-
Energy deregulation: licensing tumors to grow
-
Garber K. Energy deregulation: licensing tumors to grow. Science 2006, 312:1158-1159.
-
(2006)
Science
, vol.312
, pp. 1158-1159
-
-
Garber, K.1
-
36
-
-
78651102325
-
-
editors. Harper's illustrated biochemistry. 27th ed. New York: McGraw-Hill;
-
Murray RK, Granner DK, Rodwell VW, editors. Harper's illustrated biochemistry. 27th ed. New York: McGraw-Hill; 2006.
-
(2006)
-
-
Murray, R.K.1
Granner, D.K.2
Rodwell, V.W.3
-
37
-
-
0027511220
-
The role of the Crabtree effect and an endogenous fuel in the energy metabolism of resting and proliferating thymocytes
-
Guppy M., Geriner E., Brand K. The role of the Crabtree effect and an endogenous fuel in the energy metabolism of resting and proliferating thymocytes. Eur J Biochem 1993, 212:95-99.
-
(1993)
Eur J Biochem
, vol.212
, pp. 95-99
-
-
Guppy, M.1
Geriner, E.2
Brand, K.3
-
38
-
-
0027234775
-
Oxidation of pyruvate, malate, citrate, and cytosolic reducing equivalents by AS-30D hepatoma mitochondria
-
Dietzen D.J., Davis E.J. Oxidation of pyruvate, malate, citrate, and cytosolic reducing equivalents by AS-30D hepatoma mitochondria. Arch Biochem Biophys 1993, 305:91-102.
-
(1993)
Arch Biochem Biophys
, vol.305
, pp. 91-102
-
-
Dietzen, D.J.1
Davis, E.J.2
-
40
-
-
0023229193
-
Oxidative metabolism and glycolysis in benign brain tumors
-
Lichtor T., Dohrmann G.J. Oxidative metabolism and glycolysis in benign brain tumors. J Neurosurg 1987, 67:336-340.
-
(1987)
J Neurosurg
, vol.67
, pp. 336-340
-
-
Lichtor, T.1
Dohrmann, G.J.2
-
41
-
-
0029786667
-
Oxidative phosphorylation and F0F1 ATP synthase activity of human hepatocellular carcinoma
-
Capuano F., et al. Oxidative phosphorylation and F0F1 ATP synthase activity of human hepatocellular carcinoma. Biochem Mol Biol Int 1996, 38:1013-1022.
-
(1996)
Biochem Mol Biol Int
, vol.38
, pp. 1013-1022
-
-
Capuano, F.1
-
42
-
-
33646266734
-
Determining and understanding the control of glycolysis in fast-growth tumor cells. Flux control by an over-expressed but strongly product-inhibited hexokinase
-
Marin-Hernandez A., et al. Determining and understanding the control of glycolysis in fast-growth tumor cells. Flux control by an over-expressed but strongly product-inhibited hexokinase. FEBS J 2006, 273:1975-1988.
-
(2006)
FEBS J
, vol.273
, pp. 1975-1988
-
-
Marin-Hernandez, A.1
-
43
-
-
0023881240
-
Purification and characterization of bindable form of mitochondrial bound hexokinase from the highly glycolytic AS-30D rat hepatoma cell line
-
Nakashima R.A., Paggi M.G., Scott L.J., Pedersen P.L. Purification and characterization of bindable form of mitochondrial bound hexokinase from the highly glycolytic AS-30D rat hepatoma cell line. Cancer Res 1988, 48:913-919.
-
(1988)
Cancer Res
, vol.48
, pp. 913-919
-
-
Nakashima, R.A.1
Paggi, M.G.2
Scott, L.J.3
Pedersen, P.L.4
-
44
-
-
0021327015
-
Enzyme activities in normal, dysplastic, and cancerous human breast tissues
-
Balinsky D., Platz C.E., Lewis J.W. Enzyme activities in normal, dysplastic, and cancerous human breast tissues. J Natl Cancer Inst 1984, 72:217-224.
-
(1984)
J Natl Cancer Inst
, vol.72
, pp. 217-224
-
-
Balinsky, D.1
Platz, C.E.2
Lewis, J.W.3
-
45
-
-
0028148733
-
Acetoacetate metabolism in AS-30D hepatoma cells
-
Briscoe D.A., Fiskum G., Holleran A.L., Kelleher J.K. Acetoacetate metabolism in AS-30D hepatoma cells. Mol Cell Biochem 1994, 136:131-137.
-
(1994)
Mol Cell Biochem
, vol.136
, pp. 131-137
-
-
Briscoe, D.A.1
Fiskum, G.2
Holleran, A.L.3
Kelleher, J.K.4
-
46
-
-
0029036507
-
Glutamine transport by vesicles isolated from tumour-cell mitochondrial membrane
-
Molina M., et al. Glutamine transport by vesicles isolated from tumour-cell mitochondrial membrane. Biochem J 1995, 308:629-633.
-
(1995)
Biochem J
, vol.308
, pp. 629-633
-
-
Molina, M.1
-
47
-
-
77949967131
-
Targeting metabolic transformation for cancer therapy
-
Tennant D.A., Durán R.V., Gottlieb E. Targeting metabolic transformation for cancer therapy. Nat Rev Cancer 2010, 10:267-277.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 267-277
-
-
Tennant, D.A.1
Durán, R.V.2
Gottlieb, E.3
-
48
-
-
70349290632
-
Glutamine-dependent anapleurosis dictates glucose uptake and cell growth by regulating MondoA transcriptional activity
-
Kaadige M.R., Looper R.E., Kamalanaadhan S., Ayer D.E. Glutamine-dependent anapleurosis dictates glucose uptake and cell growth by regulating MondoA transcriptional activity. PNAS 2009, 106:14878-14883.
-
(2009)
PNAS
, vol.106
, pp. 14878-14883
-
-
Kaadige, M.R.1
Looper, R.E.2
Kamalanaadhan, S.3
Ayer, D.E.4
-
49
-
-
75149148563
-
Q's next" the diverse functions of glutamine in metabolism, cell biology and cancer
-
DeBerardinis R.J., Cheng T. Q's next" the diverse functions of glutamine in metabolism, cell biology and cancer. Oncogene 2010, 29:313-324.
-
(2010)
Oncogene
, vol.29
, pp. 313-324
-
-
DeBerardinis, R.J.1
Cheng, T.2
-
50
-
-
44849137874
-
Sugar and fat-that's where it's at: metabolic changes in tumors
-
Young C.D., Anderson S.M. Sugar and fat-that's where it's at: metabolic changes in tumors. Breast Cancer Res 2008, 10:9.
-
(2008)
Breast Cancer Res
, vol.10
, pp. 9
-
-
Young, C.D.1
Anderson, S.M.2
-
51
-
-
33744783432
-
Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology and tumour maintenance
-
Fantin V.R., St-Pierre J., Leder P. Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology and tumour maintenance. Cancer Cell 2006, 9:425-434.
-
(2006)
Cancer Cell
, vol.9
, pp. 425-434
-
-
Fantin, V.R.1
St-Pierre, J.2
Leder, P.3
-
52
-
-
57749111596
-
Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond
-
Ganapathy V., Thangaraju M., Prasad P.D. Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond. Pharmacol Ther 2009, 121:29-40.
-
(2009)
Pharmacol Ther
, vol.121
, pp. 29-40
-
-
Ganapathy, V.1
Thangaraju, M.2
Prasad, P.D.3
-
53
-
-
57449097020
-
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
-
Sonveaux P., et al. Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice. J Clin Invest 2008, 118:3930-3942.
-
(2008)
J Clin Invest
, vol.118
, pp. 3930-3942
-
-
Sonveaux, P.1
-
54
-
-
78651066535
-
Energy restriction for breast cancer prevention
-
Springer-Verlag, Berlin
-
Howell A., Chapman M., Harvie M. Energy restriction for breast cancer prevention. Cancer prevention 2009, vol. II. Springer-Verlag, Berlin.
-
(2009)
Cancer prevention
, vol.2
-
-
Howell, A.1
Chapman, M.2
Harvie, M.3
-
55
-
-
0035078661
-
A concomitant ATP-depleting strategy markedly enhances anticancer activity
-
Martin D.S., Spriggs D., Kroutcher J.A. A concomitant ATP-depleting strategy markedly enhances anticancer activity. Apoptosis 2001, 6:125-131.
-
(2001)
Apoptosis
, vol.6
, pp. 125-131
-
-
Martin, D.S.1
Spriggs, D.2
Kroutcher, J.A.3
-
57
-
-
33744828248
-
Glucose withdrawal induces oxidative stress followed by apoptosis in glioblastoma but not in normal human astrocytes
-
Jelluma N., et al. Glucose withdrawal induces oxidative stress followed by apoptosis in glioblastoma but not in normal human astrocytes. Mol Cancer Res 2006, 4:319-330.
-
(2006)
Mol Cancer Res
, vol.4
, pp. 319-330
-
-
Jelluma, N.1
-
58
-
-
0038407274
-
2-Deoxy-d-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism
-
Lin X., et al. 2-Deoxy-d-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism. Cancer Res 2003, 63:3413-3417.
-
(2003)
Cancer Res
, vol.63
, pp. 3413-3417
-
-
Lin, X.1
-
59
-
-
0037099685
-
Novel therapy for liver cancer: direct intra-arterial injection of a potent inhibitor of ATP production
-
Geschwind J.F., Georgiades C.S., Ko Y.H., Pedersen P.L. Novel therapy for liver cancer: direct intra-arterial injection of a potent inhibitor of ATP production. Cancer Res 2002, 62:3909-3913.
-
(2002)
Cancer Res
, vol.62
, pp. 3909-3913
-
-
Geschwind, J.F.1
Georgiades, C.S.2
Ko, Y.H.3
Pedersen, P.L.4
-
60
-
-
59849084800
-
Increased levels of superoxide and hydrogen peroxide mediate the differential susceptibility of cancer cells vs. normal cells to glucose deprivation
-
Aykin-Burns N., Ahmad I.M., Zhu Y., Oberley L.W., Spitz D.R. Increased levels of superoxide and hydrogen peroxide mediate the differential susceptibility of cancer cells vs. normal cells to glucose deprivation. Biochem J 2009, 418:29-37.
-
(2009)
Biochem J
, vol.418
, pp. 29-37
-
-
Aykin-Burns, N.1
Ahmad, I.M.2
Zhu, Y.3
Oberley, L.W.4
Spitz, D.R.5
-
61
-
-
4744341871
-
Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP
-
Ko Y.H., et al. Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP. Biochem Biophys Res Commun 2004, 3:269-275.
-
(2004)
Biochem Biophys Res Commun
, vol.3
, pp. 269-275
-
-
Ko, Y.H.1
-
62
-
-
57749088701
-
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
-
Wise D.R., et al. Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction. PNAS 2008, 105:18782-18787.
-
(2008)
PNAS
, vol.105
, pp. 18782-18787
-
-
Wise, D.R.1
-
63
-
-
34347402459
-
Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells
-
Yuneva M., Zamboni N., Oefner P., Sachidanandam R., Lazebnik Y. Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells. J Cell Biol 2007, 178:93-105.
-
(2007)
J Cell Biol
, vol.178
, pp. 93-105
-
-
Yuneva, M.1
Zamboni, N.2
Oefner, P.3
Sachidanandam, R.4
Lazebnik, Y.5
-
64
-
-
2542454779
-
The selfish brain: competition for energy resources
-
Peters A., et al. The selfish brain: competition for energy resources. Neurosci Biobehav Rev 2004, 28:143-180.
-
(2004)
Neurosci Biobehav Rev
, vol.28
, pp. 143-180
-
-
Peters, A.1
-
65
-
-
33746036112
-
Consensus recommendation for the use of 18F-FDG PET as an indicator of therapeutic response in patients in National Cancer Institute trials
-
Shankar L.K., et al. Consensus recommendation for the use of 18F-FDG PET as an indicator of therapeutic response in patients in National Cancer Institute trials. J Nucl Med 2006, 47:1059-1066.
-
(2006)
J Nucl Med
, vol.47
, pp. 1059-1066
-
-
Shankar, L.K.1
-
66
-
-
0033737712
-
Anatomy of SUV
-
Huang S.-C. Anatomy of SUV. Nucl Med Biol 2000, 27:643-646.
-
(2000)
Nucl Med Biol
, vol.27
, pp. 643-646
-
-
Huang, S.-C.1
-
67
-
-
0027367203
-
Standardized uptake values of normal tissues at PET with 2-[fluorine-18]-fluoro-2-deoxy-d-glucose: variations with body weight and a method for correction
-
Zasadny K.R., Wahl R.L. Standardized uptake values of normal tissues at PET with 2-[fluorine-18]-fluoro-2-deoxy-d-glucose: variations with body weight and a method for correction. Radiology 1993, 189:847-850.
-
(1993)
Radiology
, vol.189
, pp. 847-850
-
-
Zasadny, K.R.1
Wahl, R.L.2
-
68
-
-
44849103305
-
18F-FDG PET of common enhancing malignant brain tumours
-
Kosaka N., et al. 18F-FDG PET of common enhancing malignant brain tumours. AJR 2008, 190:W365-W369.
-
(2008)
AJR
, vol.190
-
-
Kosaka, N.1
-
69
-
-
33846817099
-
Severe paraneoplastic hypoglycemia in a patient with a gastrointestinal stromal tumor with an exon 9 mutation: a case report
-
Escobar G.A., et al. Severe paraneoplastic hypoglycemia in a patient with a gastrointestinal stromal tumor with an exon 9 mutation: a case report. BMC Cancer 2007, 7:6.
-
(2007)
BMC Cancer
, vol.7
, pp. 6
-
-
Escobar, G.A.1
-
70
-
-
27244442412
-
Severe hypoglycemia caused by paraneoplastic production of IGF-II in patients with advanced gastrointestinal stromal tumors: a report for two cases
-
Pink D., et al. Severe hypoglycemia caused by paraneoplastic production of IGF-II in patients with advanced gastrointestinal stromal tumors: a report for two cases. J Clin Oncol 2005, 2:6809-6811.
-
(2005)
J Clin Oncol
, vol.2
, pp. 6809-6811
-
-
Pink, D.1
-
71
-
-
0038262015
-
Common paraneoplastic syndromes
-
Finora D.V.M.K. Common paraneoplastic syndromes. Med Oncol 2003, 18:123-126.
-
(2003)
Med Oncol
, vol.18
, pp. 123-126
-
-
Finora, D.V.M.K.1
-
72
-
-
34249851195
-
Hypoglycemia due to paraneoplastic secretion of insulin-like growth factor-I in a patient with metastizing large-cell carcinoma of the lung
-
Nauck M.A., et al. Hypoglycemia due to paraneoplastic secretion of insulin-like growth factor-I in a patient with metastizing large-cell carcinoma of the lung. J Clin Endocrin Metab 2007, 92:1600-1605.
-
(2007)
J Clin Endocrin Metab
, vol.92
, pp. 1600-1605
-
-
Nauck, M.A.1
-
73
-
-
0031955474
-
Evaluation of benign and malignant hepatic lesions with positron emission tomography
-
Delbeke D., et al. Evaluation of benign and malignant hepatic lesions with positron emission tomography. Arch Surg 2009, 133:510-516.
-
(2009)
Arch Surg
, vol.133
, pp. 510-516
-
-
Delbeke, D.1
-
74
-
-
0024408986
-
Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review
-
Vaupel P., Kallinowski F., Okunieff P. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res 1989, 49:6449-6465.
-
(1989)
Cancer Res
, vol.49
, pp. 6449-6465
-
-
Vaupel, P.1
Kallinowski, F.2
Okunieff, P.3
-
75
-
-
60049083972
-
Increasing uptake time in FDG-PET: standardized uptake values in normal tissues at 1 versus 3h
-
Chin B.B., Green E.D., Turkington T.G., Hawk T.C., Coleman R.E. Increasing uptake time in FDG-PET: standardized uptake values in normal tissues at 1 versus 3h. Mol Imaging Biol 2008, 11:118-122.
-
(2008)
Mol Imaging Biol
, vol.11
, pp. 118-122
-
-
Chin, B.B.1
Green, E.D.2
Turkington, T.G.3
Hawk, T.C.4
Coleman, R.E.5
-
76
-
-
0020517073
-
Diversity of metabolic patterns in human brain tumors: enzymes of energy metabolism and related metabolites and cofactors
-
Lowrie O.H. Diversity of metabolic patterns in human brain tumors: enzymes of energy metabolism and related metabolites and cofactors. J Neurochem 1983, 41:994-1010.
-
(1983)
J Neurochem
, vol.41
, pp. 994-1010
-
-
Lowrie, O.H.1
-
77
-
-
84940799748
-
Activities of glycolytic enzymes in rapidly proliferating and differentiated C6 glioma cells
-
Dastidar S.G., Sharma S.K. Activities of glycolytic enzymes in rapidly proliferating and differentiated C6 glioma cells. Exp Cell Biol 1989, 57:159-164.
-
(1989)
Exp Cell Biol
, vol.57
, pp. 159-164
-
-
Dastidar, S.G.1
Sharma, S.K.2
-
78
-
-
34250858980
-
Correlating metabolic and anatomic responses of primary lung cancers to radiotherapy by combined F-18 FDG PET-CT imaging
-
Wong C.O., et al. Correlating metabolic and anatomic responses of primary lung cancers to radiotherapy by combined F-18 FDG PET-CT imaging. Rad Oncol 2007, 2.
-
(2007)
Rad Oncol
, pp. 2
-
-
Wong, C.O.1
-
79
-
-
0042631398
-
Positron emission tomography in non-small cell lung cancer: prediction of response to chemotherapy by quantitative assessment of glucose use
-
Weber W.A., et al. Positron emission tomography in non-small cell lung cancer: prediction of response to chemotherapy by quantitative assessment of glucose use. J Clin Oncol 2003, 21:2651-2657.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2651-2657
-
-
Weber, W.A.1
-
80
-
-
42449118429
-
Bone metastasis is patients with metastatic breast cancer: morphologic and metabolic monitoring of response to systemic therapy with integrated PET/CT
-
Tateishi U., et al. Bone metastasis is patients with metastatic breast cancer: morphologic and metabolic monitoring of response to systemic therapy with integrated PET/CT. Radiology 2008, 247:189-196.
-
(2008)
Radiology
, vol.247
, pp. 189-196
-
-
Tateishi, U.1
-
81
-
-
0024431460
-
Tumor blood flow: the principal modulator of oxidative and glycolytic metabolism, and of the metabolic micromilieu of human tumor xenografts in vivo
-
Kallinowski F., Schlenger K.H., Kloes M., Stohrer M., Vaupel P. Tumor blood flow: the principal modulator of oxidative and glycolytic metabolism, and of the metabolic micromilieu of human tumor xenografts in vivo. Int J Cancer 1989, 44:266-272.
-
(1989)
Int J Cancer
, vol.44
, pp. 266-272
-
-
Kallinowski, F.1
Schlenger, K.H.2
Kloes, M.3
Stohrer, M.4
Vaupel, P.5
-
82
-
-
27544449023
-
Quantification of cellular proliferation in tumor and normal tissues of patients with breast cancer by 18F Fluorothymidine-positron emission tomography imaging: evaluation of analytical methods
-
Kenny L.M., et al. Quantification of cellular proliferation in tumor and normal tissues of patients with breast cancer by 18F Fluorothymidine-positron emission tomography imaging: evaluation of analytical methods. Cancer Res 2005, 65:10104-10112.
-
(2005)
Cancer Res
, vol.65
, pp. 10104-10112
-
-
Kenny, L.M.1
-
83
-
-
0035176068
-
Positron emission tomography imaging of cancer: glucose metabolism and beyond
-
Mankoff D.A., Bellon J.R. Positron emission tomography imaging of cancer: glucose metabolism and beyond. Semin Radiat Oncol 2001, 11:16-27.
-
(2001)
Semin Radiat Oncol
, vol.11
, pp. 16-27
-
-
Mankoff, D.A.1
Bellon, J.R.2
-
84
-
-
66149111586
-
Early prediction of response to first-line chemotherapy by sequential [18F]-2-fluoro-deoxy-d-glucose positron emission tomography in patients with advanced colorectal cancer
-
Byström P., et al. Early prediction of response to first-line chemotherapy by sequential [18F]-2-fluoro-deoxy-d-glucose positron emission tomography in patients with advanced colorectal cancer. Ann Oncol 2009, 20:1057-1061.
-
(2009)
Ann Oncol
, vol.20
, pp. 1057-1061
-
-
Byström, P.1
-
85
-
-
33749066984
-
18F-FDG PET is an early predictor of pathologic tumor response to preoperative radiochemotherapy in locally advanced rectal cancer
-
Cascini G.L., et al. 18F-FDG PET is an early predictor of pathologic tumor response to preoperative radiochemotherapy in locally advanced rectal cancer. J Nucl Med 2007, 47:1241-1248.
-
(2007)
J Nucl Med
, vol.47
, pp. 1241-1248
-
-
Cascini, G.L.1
-
86
-
-
0032247393
-
Positron emission tomography as a diagnostic tool in oncology
-
Schiepers C., Hoh C.K. Positron emission tomography as a diagnostic tool in oncology. Eur Radiol 1998, 8:1481-1494.
-
(1998)
Eur Radiol
, vol.8
, pp. 1481-1494
-
-
Schiepers, C.1
Hoh, C.K.2
-
87
-
-
0027892859
-
Glucose metabolism in adriamycin-sensitive and -resistant LoVo human colon carcinoma cells
-
Fanciulli M., et al. Glucose metabolism in adriamycin-sensitive and -resistant LoVo human colon carcinoma cells. Oncol Res 1993, 5:357-362.
-
(1993)
Oncol Res
, vol.5
, pp. 357-362
-
-
Fanciulli, M.1
-
88
-
-
57049150308
-
[F-18]-fluorodeoxyglucose PET-CT of the normal prostate gland
-
Jadvar H., Ye W., Groshen S., Conti P.S. [F-18]-fluorodeoxyglucose PET-CT of the normal prostate gland. Ann Nucl Med 2008, 22:787-793.
-
(2008)
Ann Nucl Med
, vol.22
, pp. 787-793
-
-
Jadvar, H.1
Ye, W.2
Groshen, S.3
Conti, P.S.4
-
89
-
-
33847347586
-
Standardized uptake value atlas: characterization of physiological 2-deoxy-2-[18F] fluoro-d-glucose uptake in normal tissue
-
Wang Y., Chiu E., Rosenberg J., Gambhir S.S. Standardized uptake value atlas: characterization of physiological 2-deoxy-2-[18F] fluoro-d-glucose uptake in normal tissue. Mol Imaging Biol 2007, 9:83-90.
-
(2007)
Mol Imaging Biol
, vol.9
, pp. 83-90
-
-
Wang, Y.1
Chiu, E.2
Rosenberg, J.3
Gambhir, S.S.4
-
90
-
-
0035476881
-
The effects of increasing exercise intensity on muscle fuel utilisation in humans
-
Van Loon L.J.C., Greenhaff P.L., Constantin-Teodosiu D., Saris W.H.M., Wagenmakers A.J.M. The effects of increasing exercise intensity on muscle fuel utilisation in humans. J Physiol 2001, 536:295-304.
-
(2001)
J Physiol
, vol.536
, pp. 295-304
-
-
Van Loon, L.J.C.1
Greenhaff, P.L.2
Constantin-Teodosiu, D.3
Saris, W.H.M.4
Wagenmakers, A.J.M.5
-
92
-
-
78651068023
-
-
editors. Basic neurochemistry: molecular, cellular and medical aspects. 6th ed. Philadelphia: Lippincott-Raven Publishers
-
Siegel GJ, Agranoff BW, Fisher SK, Albers RW, Uhler MD, editors. Basic neurochemistry: molecular, cellular and medical aspects. 6th ed. Philadelphia: Lippincott-Raven Publishers; 1998.
-
(1998)
-
-
Siegel, G.J.1
Agranoff, B.W.2
Fisher, S.K.3
Albers, R.W.4
Uhler, M.D.5
-
93
-
-
34147133340
-
Hypoglycemia, functional brain failure, and brain death
-
Cryer P.E. Hypoglycemia, functional brain failure, and brain death. J Clin Invest 2007, 117:868-870.
-
(2007)
J Clin Invest
, vol.117
, pp. 868-870
-
-
Cryer, P.E.1
-
94
-
-
7944237805
-
Hypoglycemic brain damage
-
Auer R.N. Hypoglycemic brain damage. Foren Sci Int 2004, 146:105-110.
-
(2004)
Foren Sci Int
, vol.146
, pp. 105-110
-
-
Auer, R.N.1
-
95
-
-
0034981078
-
In vivo measurements of brain glucose transport using the reversible Michaelis-Menten model and simultaneous measurements of cerebral blood flow changes during hypoglycemia
-
Choi I.-Y., Lee S.-P., Kim S.-G., Gruetter R. In vivo measurements of brain glucose transport using the reversible Michaelis-Menten model and simultaneous measurements of cerebral blood flow changes during hypoglycemia. J Cereb Blood Flow Metab 2001, 21:653-663.
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 653-663
-
-
Choi, I.-Y.1
Lee, S.-P.2
Kim, S.-G.3
Gruetter, R.4
-
96
-
-
0031961946
-
Steady-state cerebral glucose concentrations and transport in the human brain
-
Gruetter R., Ugurbil K., Seaquist E.R. Steady-state cerebral glucose concentrations and transport in the human brain. J Neurochem 1998, 70:397-408.
-
(1998)
J Neurochem
, vol.70
, pp. 397-408
-
-
Gruetter, R.1
Ugurbil, K.2
Seaquist, E.R.3
-
97
-
-
64349116738
-
The rate-limiting step for glucose transport into the hypothalamus is across the blood-hypothalamus interface
-
Poitry-Yamate C., Lei H.X., Gruetter R. The rate-limiting step for glucose transport into the hypothalamus is across the blood-hypothalamus interface. J Neurochem 2009, 109(Suppl.):38-45.
-
(2009)
J Neurochem
, vol.109
, Issue.SUPPL.
, pp. 38-45
-
-
Poitry-Yamate, C.1
Lei, H.X.2
Gruetter, R.3
-
98
-
-
0003763255
-
-
Lippincott Williams and Wilkins, Baltimore, MD, P.C. Champe, R.A. Harvey (Eds.)
-
Lippincott's illustrated reviews: biochemistry 2008, Lippincott Williams and Wilkins, Baltimore, MD. P.C. Champe, R.A. Harvey (Eds.).
-
(2008)
Lippincott's illustrated reviews: biochemistry
-
-
-
99
-
-
70349086613
-
Human brain glycogen metabolism during and after hypoglycemia
-
Öz G., et al. Human brain glycogen metabolism during and after hypoglycemia. Diabetes 2009, 58:1978-1985.
-
(2009)
Diabetes
, vol.58
, pp. 1978-1985
-
-
Öz, G.1
-
100
-
-
33947102530
-
Human brain glycogen content and metabolism: implications on its role in brain energy metabolism
-
Öz G., et al. Human brain glycogen content and metabolism: implications on its role in brain energy metabolism. Am J Physiol Endocrinol Metab 2007, 292:E946-E951.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.292
-
-
Öz, G.1
-
101
-
-
0013964986
-
Hormone-fuel interrelationships during fasting
-
Cahill G.F., et al. Hormone-fuel interrelationships during fasting. J Clin Invest 1966, 45:1751-1769.
-
(1966)
J Clin Invest
, vol.45
, pp. 1751-1769
-
-
Cahill, G.F.1
-
102
-
-
4544335404
-
Glutamatergic neurotransmission and neuronal glucose oxidation are coupled during intense neuronal activation
-
Patel A.B., et al. Glutamatergic neurotransmission and neuronal glucose oxidation are coupled during intense neuronal activation. J Cereb Blood Flow 2004, 24:972-985.
-
(2004)
J Cereb Blood Flow
, vol.24
, pp. 972-985
-
-
Patel, A.B.1
-
103
-
-
15444371484
-
Management of multifactorial idiopathic epilepsy in EL mice with caloric restriction and the ketogenic diet: role of glucose and ketone bodies
-
Mantis J.G., Centeno N.A., Todorova M.T., McGowan R., Seyfried T.N. Management of multifactorial idiopathic epilepsy in EL mice with caloric restriction and the ketogenic diet: role of glucose and ketone bodies. Nutr Metab 2004, 1:11.
-
(2004)
Nutr Metab
, vol.1
, pp. 11
-
-
Mantis, J.G.1
Centeno, N.A.2
Todorova, M.T.3
McGowan, R.4
Seyfried, T.N.5
-
104
-
-
0033774531
-
Human brain β-hydroxybutyrate and lactate increase in fasting-induced ketosis
-
Pan J.W., Rothman D.L., Behar K.L., Stein D.T., Hetherington H.P. Human brain β-hydroxybutyrate and lactate increase in fasting-induced ketosis. Cereb Blood Flow Metab 2000, 20:1502-1507.
-
(2000)
Cereb Blood Flow Metab
, vol.20
, pp. 1502-1507
-
-
Pan, J.W.1
Rothman, D.L.2
Behar, K.L.3
Stein, D.T.4
Hetherington, H.P.5
-
105
-
-
78651108188
-
-
An installation and method for the treatment of cancer. International PCT/IB2008/055112,
-
Mathews EH. An installation and method for the treatment of cancer. International PCT/IB2008/055112, 2007.
-
(2007)
-
-
Mathews, E.H.1
-
106
-
-
66449133323
-
A change of strategy in the war on cancer
-
Gatenby R.A. A change of strategy in the war on cancer. Nature 2009, 459:508-509.
-
(2009)
Nature
, vol.459
, pp. 508-509
-
-
Gatenby, R.A.1
-
107
-
-
0022442374
-
IPT: a new concept in the management of chronic degenerative disease
-
Ayre S.G., Perez Garcia, Bellon D., Perez Garcia D. IPT: a new concept in the management of chronic degenerative disease. Med Hypoth 1986, 20:199-210.
-
(1986)
Med Hypoth
, vol.20
, pp. 199-210
-
-
Ayre, S.G.1
Perez Garcia2
Bellon, D.3
Perez Garcia, D.4
-
108
-
-
56749184290
-
Insulin and insulin-like growth factor signaling in neoplasia
-
Pollak M. Insulin and insulin-like growth factor signaling in neoplasia. Nat Rev Cancer 2009, 8:915-928.
-
(2009)
Nat Rev Cancer
, vol.8
, pp. 915-928
-
-
Pollak, M.1
-
109
-
-
20444461067
-
Metformin and reduced risk of cancer in diabetes patients
-
Evans J.M., Donnely L.A., Emslie-Smith A.M., Alessi D.R., Morris A.D. Metformin and reduced risk of cancer in diabetes patients. BMJ 2005, 330:1304-1305.
-
(2005)
BMJ
, vol.330
, pp. 1304-1305
-
-
Evans, J.M.1
Donnely, L.A.2
Emslie-Smith, A.M.3
Alessi, D.R.4
Morris, A.D.5
-
110
-
-
0027370355
-
Insulin-like growth factors (IGFs) and their receptors in adrenal tumours: high IGF-II expression in functional adrenocortical carcinomas
-
Ilvesmaki V., et al. Insulin-like growth factors (IGFs) and their receptors in adrenal tumours: high IGF-II expression in functional adrenocortical carcinomas. J Clin Endocrin Metab 1993, 77:852-858.
-
(1993)
J Clin Endocrin Metab
, vol.77
, pp. 852-858
-
-
Ilvesmaki, V.1
-
111
-
-
75849119306
-
Does insulin therapy promote, reduce, or have a neutral effect on cancers?
-
Gerstein H.C. Does insulin therapy promote, reduce, or have a neutral effect on cancers?. JAMA 2010, 303:446-447.
-
(2010)
JAMA
, vol.303
, pp. 446-447
-
-
Gerstein, H.C.1
-
112
-
-
78651067109
-
Using simulation to study the effect of stress on blood glucose levels
-
Hildebrand G.E., Mathews E.H. Using simulation to study the effect of stress on blood glucose levels. Diabetes 2004, 53:A516.
-
(2004)
Diabetes
, vol.53
-
-
Hildebrand, G.E.1
Mathews, E.H.2
-
113
-
-
0037627840
-
Current uses of isolated limb perfusion in the clinic and a model system for new strategies
-
Eggermont A.M.M., De Wilt J.H.W., Ten Hagen T.L.M. Current uses of isolated limb perfusion in the clinic and a model system for new strategies. Lancet Oncol 2003, 4:429-437.
-
(2003)
Lancet Oncol
, vol.4
, pp. 429-437
-
-
Eggermont, A.M.M.1
De Wilt, J.H.W.2
Ten Hagen, T.L.M.3
-
114
-
-
71549154694
-
Hyperthermic isolated limb perfusion in locally advanced soft tissue sarcoma and progressive desmoids-type fibromatosis with TNF 1 mg and melphalan (T1-M HILP) is safe and efficient
-
Bonvalot S., et al. Hyperthermic isolated limb perfusion in locally advanced soft tissue sarcoma and progressive desmoids-type fibromatosis with TNF 1 mg and melphalan (T1-M HILP) is safe and efficient. Ann Surg Oncol 2009, 16:3350-3357.
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 3350-3357
-
-
Bonvalot, S.1
-
115
-
-
21244447948
-
Isolated limb perfusion with tumor necrosis factor and melphalan prevents amputation in patients with multiple sarcomas in arm or leg
-
Grünhagen D., et al. Isolated limb perfusion with tumor necrosis factor and melphalan prevents amputation in patients with multiple sarcomas in arm or leg. Ann Surg Oncol 2005, 12:1-7.
-
(2005)
Ann Surg Oncol
, vol.12
, pp. 1-7
-
-
Grünhagen, D.1
-
116
-
-
9144253461
-
The past decade of experience with isolated hepatic perfusion
-
Grover A., Alexander H.R. The past decade of experience with isolated hepatic perfusion. Oncology 2004, 9:653-664.
-
(2004)
Oncology
, vol.9
, pp. 653-664
-
-
Grover, A.1
Alexander, H.R.2
-
117
-
-
0003802131
-
-
Lippincott, Williams and Wilkins, Philadelphia
-
Daugirdas J.T., Blake P.G., Todd S.I. Handbook of dialysis 2001, Lippincott, Williams and Wilkins, Philadelphia. 3rd ed.
-
(2001)
Handbook of dialysis
-
-
Daugirdas, J.T.1
Blake, P.G.2
Todd, S.I.3
-
120
-
-
33750110683
-
Fuel metabolism in starvation
-
Cahill G.F. Fuel metabolism in starvation. Annu Rev Nutr 2006, 26:1-22.
-
(2006)
Annu Rev Nutr
, vol.26
, pp. 1-22
-
-
Cahill, G.F.1
-
121
-
-
43649086052
-
Transcatheter arterial chemoembolization in patients with hepatocellular carcinoma on the waiting list for orthotopic liver transplantation
-
Alba E., et al. Transcatheter arterial chemoembolization in patients with hepatocellular carcinoma on the waiting list for orthotopic liver transplantation. AJR 2007, 190:1341-1348.
-
(2007)
AJR
, vol.190
, pp. 1341-1348
-
-
Alba, E.1
|