Ursodeoxycholic acid amides as novel glucocorticoid receptor modulators

Journal of Medicinal Chemistry

Volumn 54, Issue 1, 2011, Pages 122-130

  Sharma, Ruchika ^a,b   Prichard, David ^b   Majer, Ferenc ^a   Byrne, Anne Marie ^b   Kelleher, Dermot ^b   Long, Aideen ^b   Gilmer, John F ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b ST JAMES S HOSPITAL   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIGAND; TUMOR NECROSIS FACTOR ALPHA; URSODEOXYCHOLIC ACID;

ARTICLE; CANCER CELL CULTURE; DRUG ACTIVITY; DRUG EFFECT; EMBRYO; ESOPHAGUS CANCER; HEPATITIS; HUMAN; HUMAN CELL; TRANSACTIVATION;

AMIDES; BINDING SITES; BINDING, COMPETITIVE; CELL LINE, TUMOR; DEXAMETHASONE; ESOPHAGEAL NEOPLASMS; FLUORESCENCE RESONANCE ENERGY TRANSFER; GLUCOCORTICOIDS; HEK293 CELLS; HUMANS; LIGANDS; MODELS, MOLECULAR; NF-KAPPA B; PROTEIN TRANSPORT; RADIOLIGAND ASSAY; RECEPTORS, GLUCOCORTICOID; RESPONSE ELEMENTS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTIONAL ACTIVATION; TUMOR NECROSIS FACTOR-ALPHA; URSODEOXYCHOLIC ACID;

EID: 78651098672     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm100860s     Document Type: Article

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