Ursodeoxycholic acid diminishes Fas-ligand-induced apoptosis in mouse hepatocytes

Hepatology

Volumn 36, Issue 1, 2002, Pages 49-54

  Azzaroli, Francesco ^a   Mehal, Wajahat ^a   Soroka, Carol J ^a   Wang, Lin ^a   Lee, John ^a   Crispe, Nicholas ^a   Boyer, James L ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; BILE ACID; FAS LIGAND; TAUROCHENODEOXYCHOLIC ACID; TAUROCHOLIC ACID; TAUROURSODEOXYCHOLIC ACID; URSODEOXYCHOLIC ACID;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FIBROBLAST; IMMUNOHISTOCHEMISTRY; LIVER CELL; LIVER CELL CULTURE; LIVER PROTECTION; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

EID: 0036291806     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2002.34511     Document Type: Article

References (22)

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19. Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of Fas
20. Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production
21. The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade
22. Apoptosis induced in rat hepatocytes by in vivo exposure to taurochenodeoxycholate