The many faces of the YopM effector from plague causative bacterium Yersinia pestis and its implications for host immune modulation

Innate Immunity

Volumn 17, Issue 6, 2011, Pages 548-557

  Soundararajan, Venkataramanan ^a   Patel, Neel ^a   Subramanian, Vidya ^a   Sasisekharan, Viswanathan ^a   Sasisekharan, Ram ^a  

^a HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

Author keywords

Bacterial ubiquitin ligase; homology modeling; immune suppression; leucine rich repeat (LRR) domain; lipopolysaccharide (LPS); molecular mimicry; novel E3 ligase (NEL) domain; plague; Toll like receptor 4 (TLR4); Yersinia pestis; YopM effector

Indexed keywords

BACTERIAL PROTEIN; BACTERIUM LIPOPOLYSACCHARIDE; HLA DR ANTIGEN; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN YOPM; THIOREDOXIN; TOLL LIKE RECEPTOR 4; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ANTIGEN PRESENTATION; ARTICLE; AUTOREGULATION; BACTERIAL VIRULENCE; CARBOXY TERMINAL SEQUENCE; IMMUNE RESPONSE; IMMUNOGENICITY; IMMUNOMODULATION; INFLAMMATION; INNATE IMMUNITY; MOLECULAR MIMICRY; NONHUMAN; NUCLEOTIDE SEQUENCE; PLAGUE; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN MOTIF; SIGNAL TRANSDUCTION; YERSINIA PESTIS;

AMINO ACID SEQUENCE; BACTERIAL OUTER MEMBRANE PROTEINS; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, INNATE; IMMUNOMODULATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; PLAGUE; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES; YERSINIA PESTIS;

EID: 78651078179     PISSN: 17534259     EISSN: 17534267     Source Type: Journal    
DOI: 10.1177/1753425910377099     Document Type: Article

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