메뉴 건너뛰기




Volumn 12, Issue , 2011, Pages

Shb deficient mice display an augmented TH2 response in peripheral CD4+ T cells

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; PROTEIN SHB; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; LYMPHOCYTE ANTIGEN RECEPTOR; ONCOPROTEIN; SHB PROTEIN, MOUSE;

EID: 78651074922     PISSN: None     EISSN: 14712172     Source Type: Journal    
DOI: 10.1186/1471-2172-12-3     Document Type: Article
Times cited : (17)

References (56)
  • 1
    • 0037459321 scopus 로고    scopus 로고
    • Signaling life and death in the thymus: timing is everything
    • 10.1126/science.1067833, 12649474
    • Werlen G, Hausmann B, Naeher D, Palmer E. Signaling life and death in the thymus: timing is everything. Science 2003, 299:1859-63. 10.1126/science.1067833, 12649474.
    • (2003) Science , vol.299 , pp. 1859-1863
    • Werlen, G.1    Hausmann, B.2    Naeher, D.3    Palmer, E.4
  • 3
    • 0023663430 scopus 로고
    • T cell tolerance by clonal elimination in the thymus
    • 10.1016/0092-8674(87)90568-X, 3494522
    • Kappler JW, Roehm N, Marrack P. T cell tolerance by clonal elimination in the thymus. Cell 1987, 49:273-80. 10.1016/0092-8674(87)90568-X, 3494522.
    • (1987) Cell , vol.49 , pp. 273-280
    • Kappler, J.W.1    Roehm, N.2    Marrack, P.3
  • 4
    • 0023683669 scopus 로고
    • Positive selection of antigen-specific T cells in thymus by restricting MHC molecules
    • 10.1038/335730a0, 3262831
    • Kisielow P, Teh HS, Bluthmann H, von Boehmer H. Positive selection of antigen-specific T cells in thymus by restricting MHC molecules. Nature 1988, 335:730-3. 10.1038/335730a0, 3262831.
    • (1988) Nature , vol.335 , pp. 730-733
    • Kisielow, P.1    Teh, H.S.2    Bluthmann, H.3    von Boehmer, H.4
  • 5
    • 0027153201 scopus 로고
    • A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression
    • Godfrey DI, Kennedy J, Suda T, Zlotnik A. A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. J Immunol 1993, 150:4244-52.
    • (1993) J Immunol , vol.150 , pp. 4244-4252
    • Godfrey, D.I.1    Kennedy, J.2    Suda, T.3    Zlotnik, A.4
  • 6
    • 4143146469 scopus 로고    scopus 로고
    • T cell receptor antagonism interferes with MHC clustering and integrin patterning during immunological synapse formation
    • 10.1083/jcb.200404059, 2172210, 15314068
    • Sumen C, Dustin ML, Davis MM. T cell receptor antagonism interferes with MHC clustering and integrin patterning during immunological synapse formation. J Cell Biol 2004, 166:579-90. 10.1083/jcb.200404059, 2172210, 15314068.
    • (2004) J Cell Biol , vol.166 , pp. 579-590
    • Sumen, C.1    Dustin, M.L.2    Davis, M.M.3
  • 7
    • 0031979542 scopus 로고    scopus 로고
    • Structural requirements for ligand interactions at the benzodiazepine recognition site of the GABA(A) receptor
    • 10.1046/j.1471-4159.1998.70052188.x, 9572307
    • Davies M, Bateson AN, Dunn SM. Structural requirements for ligand interactions at the benzodiazepine recognition site of the GABA(A) receptor. J Neurochem 1998, 70:2188-94. 10.1046/j.1471-4159.1998.70052188.x, 9572307.
    • (1998) J Neurochem , vol.70 , pp. 2188-2194
    • Davies, M.1    Bateson, A.N.2    Dunn, S.M.3
  • 8
    • 0037331525 scopus 로고    scopus 로고
    • Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation
    • 10.1016/S1074-7613(03)00019-0, 12594952
    • Holler PD, Kranz DM. Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation. Immunity 2003, 18:255-64. 10.1016/S1074-7613(03)00019-0, 12594952.
    • (2003) Immunity , vol.18 , pp. 255-264
    • Holler, P.D.1    Kranz, D.M.2
  • 9
    • 0028928422 scopus 로고
    • Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells
    • 10.1074/jbc.270.13.7029, 7706237
    • Jackman JK, Motto DG, Sun Q, Tanemoto M, Turck CW, Peltz GA, Koretzky GA, Findell PR. Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells. J Biol Chem 1995, 270:7029-32. 10.1074/jbc.270.13.7029, 7706237.
    • (1995) J Biol Chem , vol.270 , pp. 7029-7032
    • Jackman, J.K.1    Motto, D.G.2    Sun, Q.3    Tanemoto, M.4    Turck, C.W.5    Peltz, G.A.6    Koretzky, G.A.7    Findell, P.R.8
  • 12
    • 0032498231 scopus 로고    scopus 로고
    • LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
    • 10.1016/S0092-8674(00)80901-0, 9489702
    • Zhang W, Sloan-Lancaster J, Kitchen J, Trible RP, Samelson LE. LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 1998, 92:83-92. 10.1016/S0092-8674(00)80901-0, 9489702.
    • (1998) Cell , vol.92 , pp. 83-92
    • Zhang, W.1    Sloan-Lancaster, J.2    Kitchen, J.3    Trible, R.P.4    Samelson, L.E.5
  • 13
    • 0034725625 scopus 로고    scopus 로고
    • Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling
    • 10.1074/jbc.M000404200, 10811803
    • Zhang W, Trible RP, Zhu M, Liu SK, McGlade CJ, Samelson LE. Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling. J Biol Chem 2000, 275:23355-61. 10.1074/jbc.M000404200, 10811803.
    • (2000) J Biol Chem , vol.275 , pp. 23355-23361
    • Zhang, W.1    Trible, R.P.2    Zhu, M.3    Liu, S.K.4    McGlade, C.J.5    Samelson, L.E.6
  • 14
    • 0025193117 scopus 로고
    • Stimulation of p21ras upon T-cell activation
    • 10.1038/346719a0, 2201921
    • Downward J, Graves JD, Warne PH, Rayter S, Cantrell DA. Stimulation of p21ras upon T-cell activation. Nature 1990, 346:719-23. 10.1038/346719a0, 2201921.
    • (1990) Nature , vol.346 , pp. 719-723
    • Downward, J.1    Graves, J.D.2    Warne, P.H.3    Rayter, S.4    Cantrell, D.A.5
  • 15
    • 0031909355 scopus 로고    scopus 로고
    • Cooperation between Syk and Rac1 leads to synergistic JNK activation in T lymphocytes
    • 10.1016/S1074-7613(00)80456-2, 9462509
    • Jacinto E, Werlen G, Karin M. Cooperation between Syk and Rac1 leads to synergistic JNK activation in T lymphocytes. Immunity 1998, 8:31-41. 10.1016/S1074-7613(00)80456-2, 9462509.
    • (1998) Immunity , vol.8 , pp. 31-41
    • Jacinto, E.1    Werlen, G.2    Karin, M.3
  • 16
    • 0028291525 scopus 로고
    • JNK is involved in signal integration during costimulation of T lymphocytes
    • 10.1016/0092-8674(94)90056-6, 8205621
    • Su B, Jacinto E, Hibi M, Kallunki T, Karin M, Ben-Neriah Y. JNK is involved in signal integration during costimulation of T lymphocytes. Cell 1994, 77:727-36. 10.1016/0092-8674(94)90056-6, 8205621.
    • (1994) Cell , vol.77 , pp. 727-736
    • Su, B.1    Jacinto, E.2    Hibi, M.3    Kallunki, T.4    Karin, M.5    Ben-Neriah, Y.6
  • 17
    • 0027337561 scopus 로고
    • P21ras couples the T cell antigen receptor to extracellular signal-regulated kinase 2 in T lymphocytes
    • 10.1084/jem.178.4.1199, 2191203, 8376929
    • Izquierdo M, Leevers SJ, Marshall CJ, Cantrell D. p21ras couples the T cell antigen receptor to extracellular signal-regulated kinase 2 in T lymphocytes. J Exp Med 1993, 178:1199-208. 10.1084/jem.178.4.1199, 2191203, 8376929.
    • (1993) J Exp Med , vol.178 , pp. 1199-1208
    • Izquierdo, M.1    Leevers, S.J.2    Marshall, C.J.3    Cantrell, D.4
  • 18
    • 0030903693 scopus 로고    scopus 로고
    • T cell proliferation in response to interleukins 2 and 7 requires p38MAP kinase activation
    • 10.1074/jbc.272.23.15023, 9169478
    • Crawley JB, Rawlinson L, Lali FV, Page TH, Saklatvala J, Foxwell BM. T cell proliferation in response to interleukins 2 and 7 requires p38MAP kinase activation. J Biol Chem 1997, 272:15023-7. 10.1074/jbc.272.23.15023, 9169478.
    • (1997) J Biol Chem , vol.272 , pp. 15023-15027
    • Crawley, J.B.1    Rawlinson, L.2    Lali, F.V.3    Page, T.H.4    Saklatvala, J.5    Foxwell, B.M.6
  • 19
    • 0032540906 scopus 로고    scopus 로고
    • Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development
    • 10.1126/science.281.5375.416, 9665885
    • Clements JL, Yang B, Ross-Barta SE, Eliason SL, Hrstka RF, Williamson RA, Koretzky GA. Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development. Science 1998, 281:416-9. 10.1126/science.281.5375.416, 9665885.
    • (1998) Science , vol.281 , pp. 416-419
    • Clements, J.L.1    Yang, B.2    Ross-Barta, S.E.3    Eliason, S.L.4    Hrstka, R.F.5    Williamson, R.A.6    Koretzky, G.A.7
  • 20
    • 0037154235 scopus 로고    scopus 로고
    • Differential role of SLP-76 domains in T cell development and function
    • 10.1073/pnas.022619199, 117400, 11792851
    • Kumar L, Pivniouk V, de la Fuente MA, Laouini D, Geha RS. Differential role of SLP-76 domains in T cell development and function. Proc Natl Acad Sci USA 2002, 99:884-9. 10.1073/pnas.022619199, 117400, 11792851.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 884-889
    • Kumar, L.1    Pivniouk, V.2    de la Fuente, M.A.3    Laouini, D.4    Geha, R.S.5
  • 22
    • 2542455474 scopus 로고    scopus 로고
    • The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration
    • 10.1074/jbc.M312729200, 15026417
    • Holmqvist K, Cross MJ, Rolny C, Hagerkvist R, Rahimi N, Matsumoto T, Claesson-Welsh L, Welsh M. The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration. J Biol Chem 2004, 279:22267-75. 10.1074/jbc.M312729200, 15026417.
    • (2004) J Biol Chem , vol.279 , pp. 22267-22275
    • Holmqvist, K.1    Cross, M.J.2    Rolny, C.3    Hagerkvist, R.4    Rahimi, N.5    Matsumoto, T.6    Claesson-Welsh, L.7    Welsh, M.8
  • 23
    • 0034660282 scopus 로고    scopus 로고
    • Platelet-derived growth factor-mediated signaling through the Shb adaptor protein: effects on cytoskeletal organization
    • 10.1006/excr.2000.4896, 10837138
    • Hooshmand-Rad R, Lu L, Heldin CH, Claesson-Welsh L, Welsh M. Platelet-derived growth factor-mediated signaling through the Shb adaptor protein: effects on cytoskeletal organization. Exp Cell Res 2000, 257:245-54. 10.1006/excr.2000.4896, 10837138.
    • (2000) Exp Cell Res , vol.257 , pp. 245-254
    • Hooshmand-Rad, R.1    Lu, L.2    Heldin, C.H.3    Claesson-Welsh, L.4    Welsh, M.5
  • 25
    • 0036308588 scopus 로고    scopus 로고
    • Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells
    • 10.1046/j.1432-1033.2002.03008.x, 12084069
    • Lindholm CK, Henriksson ML, Hallberg B, Welsh M. Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells. Eur J Biochem 2002, 269:3279-88. 10.1046/j.1432-1033.2002.03008.x, 12084069.
    • (2002) Eur J Biochem , vol.269 , pp. 3279-3288
    • Lindholm, C.K.1    Henriksson, M.L.2    Hallberg, B.3    Welsh, M.4
  • 26
    • 0033600754 scopus 로고    scopus 로고
    • Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells
    • 10.1074/jbc.274.39.28050, 10488157
    • Lindholm CK, Gylfe E, Zhang W, Samelson LE, Welsh M. Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells. J Biol Chem 1999, 274:28050-7. 10.1074/jbc.274.39.28050, 10488157.
    • (1999) J Biol Chem , vol.274 , pp. 28050-28057
    • Lindholm, C.K.1    Gylfe, E.2    Zhang, W.3    Samelson, L.E.4    Welsh, M.5
  • 27
    • 34548860663 scopus 로고    scopus 로고
    • Shb null allele is inherited with a transmission ratio distortion and causes reduced viability in utero
    • 10.1002/dvdy.21257, 17676633
    • Kriz V, Mares J, Wentzel P, Funa NS, Calounova G, Zhang XQ, Forsberg-Nilsson K, Forsberg M, Welsh M. Shb null allele is inherited with a transmission ratio distortion and causes reduced viability in utero. Dev Dyn 2007, 236:2485-92. 10.1002/dvdy.21257, 17676633.
    • (2007) Dev Dyn , vol.236 , pp. 2485-2492
    • Kriz, V.1    Mares, J.2    Wentzel, P.3    Funa, N.S.4    Calounova, G.5    Zhang, X.Q.6    Forsberg-Nilsson, K.7    Forsberg, M.8    Welsh, M.9
  • 28
    • 62449083531 scopus 로고    scopus 로고
    • Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth
    • 10.1158/0008-5472.CAN-08-3797, 19223532
    • Funa NS, Kriz V, Zang G, Calounova G, Akerblom B, Mares J, Larsson E, Sun Y, Betsholtz C, Welsh M. Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth. Cancer Res 2009, 69:2141-8. 10.1158/0008-5472.CAN-08-3797, 19223532.
    • (2009) Cancer Res , vol.69 , pp. 2141-2148
    • Funa, N.S.1    Kriz, V.2    Zang, G.3    Calounova, G.4    Akerblom, B.5    Mares, J.6    Larsson, E.7    Sun, Y.8    Betsholtz, C.9    Welsh, M.10
  • 30
    • 77955298871 scopus 로고    scopus 로고
    • The Src Homology 2 Domain-Containing Adapter Protein B (SHB) Regulates Mouse Oocyte Maturation
    • 10.1371/journal.pone.0011155, 2886836, 20585392
    • Calnouva GL, Gabriel, Zhang, Xiao-Qun, Liu, Kui, Godsen, Roger, Welsh, Michael. The Src Homology 2 Domain-Containing Adapter Protein B (SHB) Regulates Mouse Oocyte Maturation. PLoS one 2010, 5:e11155. 10.1371/journal.pone.0011155, 2886836, 20585392.
    • (2010) PLoS one , vol.5
    • Calnouva, G.L.1    Gabriel2    Zhang3    Xiao-Qun4    Liu5    Kui6    Godsen7    Roger8    Welsh9    Michael10
  • 31
    • 0029760277 scopus 로고    scopus 로고
    • Apoptosis of NIH3T3 cells overexpressing the Src homology 2 domain protein Shb
    • Karlsson T, Welsh M. Apoptosis of NIH3T3 cells overexpressing the Src homology 2 domain protein Shb. Oncogene 1996, 13:955-61.
    • (1996) Oncogene , vol.13 , pp. 955-961
    • Karlsson, T.1    Welsh, M.2
  • 32
    • 27644546643 scopus 로고    scopus 로고
    • The Rb1 fraction of ginseng elicits a balanced Th1 and Th2 immune response
    • 10.1016/j.vaccine.2005.04.007, 16286158
    • Rivera E, Pettersson Ekholm F, Inganas M, Paulie S, Gronvik KO. The Rb1 fraction of ginseng elicits a balanced Th1 and Th2 immune response. Vaccine 2005, 23:5411-9. 10.1016/j.vaccine.2005.04.007, 16286158.
    • (2005) Vaccine , vol.23 , pp. 5411-5419
    • Rivera, E.1    Pettersson Ekholm, F.2    Inganas, M.3    Paulie, S.4    Gronvik, K.O.5
  • 33
    • 0028859281 scopus 로고
    • Selective requirement for MAP kinase activation in thymocyte differentiation
    • 10.1038/373620a0, 7854419
    • Alberola-Ila J, Forbush KA, Seger R, Krebs EG, Perlmutter RM. Selective requirement for MAP kinase activation in thymocyte differentiation. Nature 1995, 373:620-3. 10.1038/373620a0, 7854419.
    • (1995) Nature , vol.373 , pp. 620-623
    • Alberola-Ila, J.1    Forbush, K.A.2    Seger, R.3    Krebs, E.G.4    Perlmutter, R.M.5
  • 34
    • 17144458301 scopus 로고    scopus 로고
    • Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice
    • 10.1126/science.286.5443.1374, 10558995
    • Pages G, Guerin S, Grall D, Bonino F, Smith A, Anjuere F, Auberger P, Pouyssegur J. Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice. Science 1999, 286:1374-7. 10.1126/science.286.5443.1374, 10558995.
    • (1999) Science , vol.286 , pp. 1374-1377
    • Pages, G.1    Guerin, S.2    Grall, D.3    Bonino, F.4    Smith, A.5    Anjuere, F.6    Auberger, P.7    Pouyssegur, J.8
  • 35
    • 0023119089 scopus 로고
    • Cell kinetics in the fetal mouse thymus: precursor cell input, proliferation, and emigration
    • Jotereau F, Heuze F, Salomon-Vie V, Gascan H. Cell kinetics in the fetal mouse thymus: precursor cell input, proliferation, and emigration. J Immunol 1987, 138:1026-30.
    • (1987) J Immunol , vol.138 , pp. 1026-1030
    • Jotereau, F.1    Heuze, F.2    Salomon-Vie, V.3    Gascan, H.4
  • 36
    • 0024109960 scopus 로고
    • Thymocytes expressing CD8 differentiate into CD4+ cells following intrathymic injection
    • 10.1073/pnas.85.22.8633, 282513, 3141930
    • Nikolic-Zugic J, Bevan MJ. Thymocytes expressing CD8 differentiate into CD4+ cells following intrathymic injection. Proc Natl Acad Sci USA 1988, 85:8633-7. 10.1073/pnas.85.22.8633, 282513, 3141930.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 8633-8637
    • Nikolic-Zugic, J.1    Bevan, M.J.2
  • 37
    • 0011156716 scopus 로고
    • Intrathymic maturation of murine T lymphocytes from CD8+ precursors
    • 10.1073/pnas.86.19.7542, 298101, 2508090
    • Guidos CJ, Weissman IL, Adkins B. Intrathymic maturation of murine T lymphocytes from CD8+ precursors. Proc Natl Acad Sci USA 1989, 86:7542-6. 10.1073/pnas.86.19.7542, 298101, 2508090.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 7542-7546
    • Guidos, C.J.1    Weissman, I.L.2    Adkins, B.3
  • 38
    • 0021346701 scopus 로고
    • Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway
    • 10.1073/pnas.81.5.1509, 344866, 6231642
    • Meuer SC, Hussey RE, Cantrell DA, Hodgdon JC, Schlossman SF, Smith KA, Reinherz EL. Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway. Proc Natl Acad Sci USA 1984, 81:1509-13. 10.1073/pnas.81.5.1509, 344866, 6231642.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 1509-1513
    • Meuer, S.C.1    Hussey, R.E.2    Cantrell, D.A.3    Hodgdon, J.C.4    Schlossman, S.F.5    Smith, K.A.6    Reinherz, E.L.7
  • 39
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • 10.1038/383787a0, 8893001
    • Abbas AK, Murphy KM, Sher A. Functional diversity of helper T lymphocytes. Nature 1996, 383:787-93. 10.1038/383787a0, 8893001.
    • (1996) Nature , vol.383 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 41
    • 0027262235 scopus 로고
    • Control of lymphocyte recirculation in man. I. Differential regulation of the peripheral lymph node homing receptor L-selectin on T cells during the virgin to memory cell transition
    • Picker LJ, Treer JR, Ferguson-Darnell B, Collins PA, Buck D, Terstappen LW. Control of lymphocyte recirculation in man. I. Differential regulation of the peripheral lymph node homing receptor L-selectin on T cells during the virgin to memory cell transition. J Immunol 1993, 150:1105-21.
    • (1993) J Immunol , vol.150 , pp. 1105-1121
    • Picker, L.J.1    Treer, J.R.2    Ferguson-Darnell, B.3    Collins, P.A.4    Buck, D.5    Terstappen, L.W.6
  • 42
    • 0029076926 scopus 로고
    • Expression in vivo of CD45RA, CD45RB and CD44 on T cell receptor-transgenic CD8+ T cells following immunization
    • 10.1002/eji.1830250640, 7542202
    • Pihlgren M, Lightstone L, Mamalaki C, Rimon G, Kioussis D, Marvel J. Expression in vivo of CD45RA, CD45RB and CD44 on T cell receptor-transgenic CD8+ T cells following immunization. Eur J Immunol 1995, 25:1755-9. 10.1002/eji.1830250640, 7542202.
    • (1995) Eur J Immunol , vol.25 , pp. 1755-1759
    • Pihlgren, M.1    Lightstone, L.2    Mamalaki, C.3    Rimon, G.4    Kioussis, D.5    Marvel, J.6
  • 43
    • 0030810155 scopus 로고    scopus 로고
    • The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
    • 10.1016/S0092-8674(00)80240-8, 9160750
    • Zheng W, Flavell RA. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 1997, 89:587-96. 10.1016/S0092-8674(00)80240-8, 9160750.
    • (1997) Cell , vol.89 , pp. 587-596
    • Zheng, W.1    Flavell, R.A.2
  • 44
    • 0034677646 scopus 로고    scopus 로고
    • A novel transcription factor, T-bet, directs Th1 lineage commitment
    • 10.1016/S0092-8674(00)80702-3, 10761931
    • Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 2000, 100:655-69. 10.1016/S0092-8674(00)80702-3, 10761931.
    • (2000) Cell , vol.100 , pp. 655-669
    • Szabo, S.J.1    Kim, S.T.2    Costa, G.L.3    Zhang, X.4    Fathman, C.G.5    Glimcher, L.H.6
  • 45
    • 2342475200 scopus 로고    scopus 로고
    • T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression
    • 10.1371/journal.pbio.0000053, 261890, 14624253
    • Roose JP, Diehn M, Tomlinson MG, Lin J, Alizadeh AA, Botstein D, Brown PO, Weiss A. T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression. PLoS Biol 2003, 1:E53. 10.1371/journal.pbio.0000053, 261890, 14624253.
    • (2003) PLoS Biol , vol.1
    • Roose, J.P.1    Diehn, M.2    Tomlinson, M.G.3    Lin, J.4    Alizadeh, A.A.5    Botstein, D.6    Brown, P.O.7    Weiss, A.8
  • 47
    • 68649087416 scopus 로고    scopus 로고
    • Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor
    • 10.1016/j.immuni.2009.05.013, 19682930
    • Mingueneau M, Roncagalli R, Gregoire C, Kissenpfennig A, Miazek A, Archambaud C, Wang Y, Perrin P, Bertosio E, Sansoni A, et al. Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor. Immunity 2009, 31:197-208. 10.1016/j.immuni.2009.05.013, 19682930.
    • (2009) Immunity , vol.31 , pp. 197-208
    • Mingueneau, M.1    Roncagalli, R.2    Gregoire, C.3    Kissenpfennig, A.4    Miazek, A.5    Archambaud, C.6    Wang, Y.7    Perrin, P.8    Bertosio, E.9    Sansoni, A.10
  • 48
    • 0032438114 scopus 로고    scopus 로고
    • Altered thymic positive selection and intracellular signals in Cbl-deficient mice
    • 10.1073/pnas.95.26.15547, 28080, 9861006
    • Naramura M, Kole HK, Hu RJ, Gu H. Altered thymic positive selection and intracellular signals in Cbl-deficient mice. Proc Natl Acad Sci USA 1998, 95:15547-52. 10.1073/pnas.95.26.15547, 28080, 9861006.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15547-15552
    • Naramura, M.1    Kole, H.K.2    Hu, R.J.3    Gu, H.4
  • 49
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986, 136:2348-57.
    • (1986) J Immunol , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 50
    • 23744484121 scopus 로고    scopus 로고
    • Impaired IL-4 and c-Maf expression and enhanced Th1-cell development in Vav1-deficient mice
    • 10.1182/blood-2004-10-4074, 1895205, 15845902
    • Tanaka Y, So T, Lebedeva S, Croft M, Altman A. Impaired IL-4 and c-Maf expression and enhanced Th1-cell development in Vav1-deficient mice. Blood 2005, 106:1286-95. 10.1182/blood-2004-10-4074, 1895205, 15845902.
    • (2005) Blood , vol.106 , pp. 1286-1295
    • Tanaka, Y.1    So, T.2    Lebedeva, S.3    Croft, M.4    Altman, A.5
  • 51
    • 0034176032 scopus 로고    scopus 로고
    • Vav synergizes with protein kinase C theta to mediate IL-4 gene expression in response to CD28 costimulation in T cells
    • Hehner SP, Li-Weber M, Giaisi M, Droge W, Krammer PH, Schmitz ML. Vav synergizes with protein kinase C theta to mediate IL-4 gene expression in response to CD28 costimulation in T cells. J Immunol 2000, 164:3829-36.
    • (2000) J Immunol , vol.164 , pp. 3829-3836
    • Hehner, S.P.1    Li-Weber, M.2    Giaisi, M.3    Droge, W.4    Krammer, P.H.5    Schmitz, M.L.6
  • 52
    • 0029788387 scopus 로고    scopus 로고
    • Cytokine transcriptional events during helper T cell subset differentiation
    • 10.1084/jem.184.2.397, 2192740, 8760793
    • Lederer JA, Perez VL, DesRoches L, Kim SM, Abbas AK, Lichtman AH. Cytokine transcriptional events during helper T cell subset differentiation. J Exp Med 1996, 184:397-406. 10.1084/jem.184.2.397, 2192740, 8760793.
    • (1996) J Exp Med , vol.184 , pp. 397-406
    • Lederer, J.A.1    Perez, V.L.2    DesRoches, L.3    Kim, S.M.4    Abbas, A.K.5    Lichtman, A.H.6
  • 53
    • 0038638583 scopus 로고    scopus 로고
    • An epigenetic view of helper T cell differentiation
    • 10.1038/ni0703-616, 12830136
    • Ansel KM, Lee DU, Rao A. An epigenetic view of helper T cell differentiation. Nat Immunol 2003, 4:616-23. 10.1038/ni0703-616, 12830136.
    • (2003) Nat Immunol , vol.4 , pp. 616-623
    • Ansel, K.M.1    Lee, D.U.2    Rao, A.3
  • 54
    • 10344234192 scopus 로고    scopus 로고
    • Th2-specific chromatin remodeling and enhancer activity in the Th2 cytokine locus control region
    • 10.1016/j.immuni.2004.10.015, 15589174
    • Fields PE, Lee GR, Kim ST, Bartsevich VV, Flavell RA. Th2-specific chromatin remodeling and enhancer activity in the Th2 cytokine locus control region. Immunity 2004, 21:865-76. 10.1016/j.immuni.2004.10.015, 15589174.
    • (2004) Immunity , vol.21 , pp. 865-876
    • Fields, P.E.1    Lee, G.R.2    Kim, S.T.3    Bartsevich, V.V.4    Flavell, R.A.5
  • 55
    • 0036667345 scopus 로고    scopus 로고
    • In TH2 cells the Il4 gene has a series of accessibility states associated with distinctive probabilities of IL-4 production
    • 10.1073/pnas.162360199, 124993, 12149469
    • Guo L, Hu-Li J, Zhu J, Watson CJ, Difilippantonio MJ, Pannetier C, Paul WE. In TH2 cells the Il4 gene has a series of accessibility states associated with distinctive probabilities of IL-4 production. Proc Natl Acad Sci USA 2002, 99:10623-8. 10.1073/pnas.162360199, 124993, 12149469.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 10623-10628
    • Guo, L.1    Hu-Li, J.2    Zhu, J.3    Watson, C.J.4    Difilippantonio, M.J.5    Pannetier, C.6    Paul, W.E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.