-
1
-
-
0037459321
-
Signaling life and death in the thymus: timing is everything
-
10.1126/science.1067833, 12649474
-
Werlen G, Hausmann B, Naeher D, Palmer E. Signaling life and death in the thymus: timing is everything. Science 2003, 299:1859-63. 10.1126/science.1067833, 12649474.
-
(2003)
Science
, vol.299
, pp. 1859-1863
-
-
Werlen, G.1
Hausmann, B.2
Naeher, D.3
Palmer, E.4
-
2
-
-
0033009891
-
Selection of the T cell repertoire
-
10.1146/annurev.immunol.17.1.829, 10358775
-
Sebzda E, Mariathasan S, Ohteki T, Jones R, Bachmann MF, Ohashi PS. Selection of the T cell repertoire. Annu Rev Immunol 1999, 17:829-74. 10.1146/annurev.immunol.17.1.829, 10358775.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 829-874
-
-
Sebzda, E.1
Mariathasan, S.2
Ohteki, T.3
Jones, R.4
Bachmann, M.F.5
Ohashi, P.S.6
-
3
-
-
0023663430
-
T cell tolerance by clonal elimination in the thymus
-
10.1016/0092-8674(87)90568-X, 3494522
-
Kappler JW, Roehm N, Marrack P. T cell tolerance by clonal elimination in the thymus. Cell 1987, 49:273-80. 10.1016/0092-8674(87)90568-X, 3494522.
-
(1987)
Cell
, vol.49
, pp. 273-280
-
-
Kappler, J.W.1
Roehm, N.2
Marrack, P.3
-
4
-
-
0023683669
-
Positive selection of antigen-specific T cells in thymus by restricting MHC molecules
-
10.1038/335730a0, 3262831
-
Kisielow P, Teh HS, Bluthmann H, von Boehmer H. Positive selection of antigen-specific T cells in thymus by restricting MHC molecules. Nature 1988, 335:730-3. 10.1038/335730a0, 3262831.
-
(1988)
Nature
, vol.335
, pp. 730-733
-
-
Kisielow, P.1
Teh, H.S.2
Bluthmann, H.3
von Boehmer, H.4
-
5
-
-
0027153201
-
A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression
-
Godfrey DI, Kennedy J, Suda T, Zlotnik A. A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. J Immunol 1993, 150:4244-52.
-
(1993)
J Immunol
, vol.150
, pp. 4244-4252
-
-
Godfrey, D.I.1
Kennedy, J.2
Suda, T.3
Zlotnik, A.4
-
6
-
-
4143146469
-
T cell receptor antagonism interferes with MHC clustering and integrin patterning during immunological synapse formation
-
10.1083/jcb.200404059, 2172210, 15314068
-
Sumen C, Dustin ML, Davis MM. T cell receptor antagonism interferes with MHC clustering and integrin patterning during immunological synapse formation. J Cell Biol 2004, 166:579-90. 10.1083/jcb.200404059, 2172210, 15314068.
-
(2004)
J Cell Biol
, vol.166
, pp. 579-590
-
-
Sumen, C.1
Dustin, M.L.2
Davis, M.M.3
-
7
-
-
0031979542
-
Structural requirements for ligand interactions at the benzodiazepine recognition site of the GABA(A) receptor
-
10.1046/j.1471-4159.1998.70052188.x, 9572307
-
Davies M, Bateson AN, Dunn SM. Structural requirements for ligand interactions at the benzodiazepine recognition site of the GABA(A) receptor. J Neurochem 1998, 70:2188-94. 10.1046/j.1471-4159.1998.70052188.x, 9572307.
-
(1998)
J Neurochem
, vol.70
, pp. 2188-2194
-
-
Davies, M.1
Bateson, A.N.2
Dunn, S.M.3
-
8
-
-
0037331525
-
Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation
-
10.1016/S1074-7613(03)00019-0, 12594952
-
Holler PD, Kranz DM. Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation. Immunity 2003, 18:255-64. 10.1016/S1074-7613(03)00019-0, 12594952.
-
(2003)
Immunity
, vol.18
, pp. 255-264
-
-
Holler, P.D.1
Kranz, D.M.2
-
9
-
-
0028928422
-
Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells
-
10.1074/jbc.270.13.7029, 7706237
-
Jackman JK, Motto DG, Sun Q, Tanemoto M, Turck CW, Peltz GA, Koretzky GA, Findell PR. Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells. J Biol Chem 1995, 270:7029-32. 10.1074/jbc.270.13.7029, 7706237.
-
(1995)
J Biol Chem
, vol.270
, pp. 7029-7032
-
-
Jackman, J.K.1
Motto, D.G.2
Sun, Q.3
Tanemoto, M.4
Turck, C.W.5
Peltz, G.A.6
Koretzky, G.A.7
Findell, P.R.8
-
10
-
-
0000082758
-
Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function
-
10.1074/jbc.271.33.19641, 8702662
-
Wardenburg Bubeck J, Fu C, Jackman JK, Flotow H, Wilkinson SE, Williams DH, Johnson R, Kong G, Chan AC, Findell PR. Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function. J Biol Chem 1996, 271:19641-4. 10.1074/jbc.271.33.19641, 8702662.
-
(1996)
J Biol Chem
, vol.271
, pp. 19641-19644
-
-
Wardenburg Bubeck, J.1
Fu, C.2
Jackman, J.K.3
Flotow, H.4
Wilkinson, S.E.5
Williams, D.H.6
Johnson, R.7
Kong, G.8
Chan, A.C.9
Findell, P.R.10
-
11
-
-
0033103833
-
Essential role of LAT in T cell development
-
10.1016/S1074-7613(00)80032-1, 10204488
-
Zhang W, Sommers CL, Burshtyn DN, Stebbins CC, DeJarnette JB, Trible RP, Grinberg A, Tsay HC, Jacobs HM, Kessler CM, et al. Essential role of LAT in T cell development. Immunity 1999, 10:323-32. 10.1016/S1074-7613(00)80032-1, 10204488.
-
(1999)
Immunity
, vol.10
, pp. 323-332
-
-
Zhang, W.1
Sommers, C.L.2
Burshtyn, D.N.3
Stebbins, C.C.4
DeJarnette, J.B.5
Trible, R.P.6
Grinberg, A.7
Tsay, H.C.8
Jacobs, H.M.9
Kessler, C.M.10
-
12
-
-
0032498231
-
LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
-
10.1016/S0092-8674(00)80901-0, 9489702
-
Zhang W, Sloan-Lancaster J, Kitchen J, Trible RP, Samelson LE. LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 1998, 92:83-92. 10.1016/S0092-8674(00)80901-0, 9489702.
-
(1998)
Cell
, vol.92
, pp. 83-92
-
-
Zhang, W.1
Sloan-Lancaster, J.2
Kitchen, J.3
Trible, R.P.4
Samelson, L.E.5
-
13
-
-
0034725625
-
Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling
-
10.1074/jbc.M000404200, 10811803
-
Zhang W, Trible RP, Zhu M, Liu SK, McGlade CJ, Samelson LE. Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling. J Biol Chem 2000, 275:23355-61. 10.1074/jbc.M000404200, 10811803.
-
(2000)
J Biol Chem
, vol.275
, pp. 23355-23361
-
-
Zhang, W.1
Trible, R.P.2
Zhu, M.3
Liu, S.K.4
McGlade, C.J.5
Samelson, L.E.6
-
14
-
-
0025193117
-
Stimulation of p21ras upon T-cell activation
-
10.1038/346719a0, 2201921
-
Downward J, Graves JD, Warne PH, Rayter S, Cantrell DA. Stimulation of p21ras upon T-cell activation. Nature 1990, 346:719-23. 10.1038/346719a0, 2201921.
-
(1990)
Nature
, vol.346
, pp. 719-723
-
-
Downward, J.1
Graves, J.D.2
Warne, P.H.3
Rayter, S.4
Cantrell, D.A.5
-
15
-
-
0031909355
-
Cooperation between Syk and Rac1 leads to synergistic JNK activation in T lymphocytes
-
10.1016/S1074-7613(00)80456-2, 9462509
-
Jacinto E, Werlen G, Karin M. Cooperation between Syk and Rac1 leads to synergistic JNK activation in T lymphocytes. Immunity 1998, 8:31-41. 10.1016/S1074-7613(00)80456-2, 9462509.
-
(1998)
Immunity
, vol.8
, pp. 31-41
-
-
Jacinto, E.1
Werlen, G.2
Karin, M.3
-
16
-
-
0028291525
-
JNK is involved in signal integration during costimulation of T lymphocytes
-
10.1016/0092-8674(94)90056-6, 8205621
-
Su B, Jacinto E, Hibi M, Kallunki T, Karin M, Ben-Neriah Y. JNK is involved in signal integration during costimulation of T lymphocytes. Cell 1994, 77:727-36. 10.1016/0092-8674(94)90056-6, 8205621.
-
(1994)
Cell
, vol.77
, pp. 727-736
-
-
Su, B.1
Jacinto, E.2
Hibi, M.3
Kallunki, T.4
Karin, M.5
Ben-Neriah, Y.6
-
17
-
-
0027337561
-
P21ras couples the T cell antigen receptor to extracellular signal-regulated kinase 2 in T lymphocytes
-
10.1084/jem.178.4.1199, 2191203, 8376929
-
Izquierdo M, Leevers SJ, Marshall CJ, Cantrell D. p21ras couples the T cell antigen receptor to extracellular signal-regulated kinase 2 in T lymphocytes. J Exp Med 1993, 178:1199-208. 10.1084/jem.178.4.1199, 2191203, 8376929.
-
(1993)
J Exp Med
, vol.178
, pp. 1199-1208
-
-
Izquierdo, M.1
Leevers, S.J.2
Marshall, C.J.3
Cantrell, D.4
-
18
-
-
0030903693
-
T cell proliferation in response to interleukins 2 and 7 requires p38MAP kinase activation
-
10.1074/jbc.272.23.15023, 9169478
-
Crawley JB, Rawlinson L, Lali FV, Page TH, Saklatvala J, Foxwell BM. T cell proliferation in response to interleukins 2 and 7 requires p38MAP kinase activation. J Biol Chem 1997, 272:15023-7. 10.1074/jbc.272.23.15023, 9169478.
-
(1997)
J Biol Chem
, vol.272
, pp. 15023-15027
-
-
Crawley, J.B.1
Rawlinson, L.2
Lali, F.V.3
Page, T.H.4
Saklatvala, J.5
Foxwell, B.M.6
-
19
-
-
0032540906
-
Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development
-
10.1126/science.281.5375.416, 9665885
-
Clements JL, Yang B, Ross-Barta SE, Eliason SL, Hrstka RF, Williamson RA, Koretzky GA. Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development. Science 1998, 281:416-9. 10.1126/science.281.5375.416, 9665885.
-
(1998)
Science
, vol.281
, pp. 416-419
-
-
Clements, J.L.1
Yang, B.2
Ross-Barta, S.E.3
Eliason, S.L.4
Hrstka, R.F.5
Williamson, R.A.6
Koretzky, G.A.7
-
20
-
-
0037154235
-
Differential role of SLP-76 domains in T cell development and function
-
10.1073/pnas.022619199, 117400, 11792851
-
Kumar L, Pivniouk V, de la Fuente MA, Laouini D, Geha RS. Differential role of SLP-76 domains in T cell development and function. Proc Natl Acad Sci USA 2002, 99:884-9. 10.1073/pnas.022619199, 117400, 11792851.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 884-889
-
-
Kumar, L.1
Pivniouk, V.2
de la Fuente, M.A.3
Laouini, D.4
Geha, R.S.5
-
21
-
-
0037076975
-
A LAT mutation that inhibits T cell development yet induces lymphoproliferation
-
10.1126/science.1069066, 12065840
-
Sommers CL, Park CS, Lee J, Feng C, Fuller CL, Grinberg A, Hildebrand JA, Lacana E, Menon RK, Shores EW, et al. A LAT mutation that inhibits T cell development yet induces lymphoproliferation. Science 2002, 296:2040-3. 10.1126/science.1069066, 12065840.
-
(2002)
Science
, vol.296
, pp. 2040-2043
-
-
Sommers, C.L.1
Park, C.S.2
Lee, J.3
Feng, C.4
Fuller, C.L.5
Grinberg, A.6
Hildebrand, J.A.7
Lacana, E.8
Menon, R.K.9
Shores, E.W.10
-
22
-
-
2542455474
-
The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration
-
10.1074/jbc.M312729200, 15026417
-
Holmqvist K, Cross MJ, Rolny C, Hagerkvist R, Rahimi N, Matsumoto T, Claesson-Welsh L, Welsh M. The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration. J Biol Chem 2004, 279:22267-75. 10.1074/jbc.M312729200, 15026417.
-
(2004)
J Biol Chem
, vol.279
, pp. 22267-22275
-
-
Holmqvist, K.1
Cross, M.J.2
Rolny, C.3
Hagerkvist, R.4
Rahimi, N.5
Matsumoto, T.6
Claesson-Welsh, L.7
Welsh, M.8
-
23
-
-
0034660282
-
Platelet-derived growth factor-mediated signaling through the Shb adaptor protein: effects on cytoskeletal organization
-
10.1006/excr.2000.4896, 10837138
-
Hooshmand-Rad R, Lu L, Heldin CH, Claesson-Welsh L, Welsh M. Platelet-derived growth factor-mediated signaling through the Shb adaptor protein: effects on cytoskeletal organization. Exp Cell Res 2000, 257:245-54. 10.1006/excr.2000.4896, 10837138.
-
(2000)
Exp Cell Res
, vol.257
, pp. 245-254
-
-
Hooshmand-Rad, R.1
Lu, L.2
Heldin, C.H.3
Claesson-Welsh, L.4
Welsh, M.5
-
24
-
-
15444352825
-
Stimulation through the T cell receptor leads to interactions between SHB and several signaling proteins
-
10.1038/sj.onc.1201607, 9484780
-
Welsh M, Songyang Z, Frantz JD, Trub T, Reedquist KA, Karlsson T, Miyazaki M, Cantley LC, Band H, Shoelson SE. Stimulation through the T cell receptor leads to interactions between SHB and several signaling proteins. Oncogene 1998, 16:891-901. 10.1038/sj.onc.1201607, 9484780.
-
(1998)
Oncogene
, vol.16
, pp. 891-901
-
-
Welsh, M.1
Songyang, Z.2
Frantz, J.D.3
Trub, T.4
Reedquist, K.A.5
Karlsson, T.6
Miyazaki, M.7
Cantley, L.C.8
Band, H.9
Shoelson, S.E.10
-
25
-
-
0036308588
-
Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells
-
10.1046/j.1432-1033.2002.03008.x, 12084069
-
Lindholm CK, Henriksson ML, Hallberg B, Welsh M. Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells. Eur J Biochem 2002, 269:3279-88. 10.1046/j.1432-1033.2002.03008.x, 12084069.
-
(2002)
Eur J Biochem
, vol.269
, pp. 3279-3288
-
-
Lindholm, C.K.1
Henriksson, M.L.2
Hallberg, B.3
Welsh, M.4
-
26
-
-
0033600754
-
Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells
-
10.1074/jbc.274.39.28050, 10488157
-
Lindholm CK, Gylfe E, Zhang W, Samelson LE, Welsh M. Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells. J Biol Chem 1999, 274:28050-7. 10.1074/jbc.274.39.28050, 10488157.
-
(1999)
J Biol Chem
, vol.274
, pp. 28050-28057
-
-
Lindholm, C.K.1
Gylfe, E.2
Zhang, W.3
Samelson, L.E.4
Welsh, M.5
-
27
-
-
34548860663
-
Shb null allele is inherited with a transmission ratio distortion and causes reduced viability in utero
-
10.1002/dvdy.21257, 17676633
-
Kriz V, Mares J, Wentzel P, Funa NS, Calounova G, Zhang XQ, Forsberg-Nilsson K, Forsberg M, Welsh M. Shb null allele is inherited with a transmission ratio distortion and causes reduced viability in utero. Dev Dyn 2007, 236:2485-92. 10.1002/dvdy.21257, 17676633.
-
(2007)
Dev Dyn
, vol.236
, pp. 2485-2492
-
-
Kriz, V.1
Mares, J.2
Wentzel, P.3
Funa, N.S.4
Calounova, G.5
Zhang, X.Q.6
Forsberg-Nilsson, K.7
Forsberg, M.8
Welsh, M.9
-
28
-
-
62449083531
-
Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth
-
10.1158/0008-5472.CAN-08-3797, 19223532
-
Funa NS, Kriz V, Zang G, Calounova G, Akerblom B, Mares J, Larsson E, Sun Y, Betsholtz C, Welsh M. Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth. Cancer Res 2009, 69:2141-8. 10.1158/0008-5472.CAN-08-3797, 19223532.
-
(2009)
Cancer Res
, vol.69
, pp. 2141-2148
-
-
Funa, N.S.1
Kriz, V.2
Zang, G.3
Calounova, G.4
Akerblom, B.5
Mares, J.6
Larsson, E.7
Sun, Y.8
Betsholtz, C.9
Welsh, M.10
-
29
-
-
70449421920
-
Impaired glucose homeostasis in Shb-/- mice
-
10.1677/JOE-09-0198, 19696098
-
Akerblom B, Barg S, Calounova G, Mokhtari D, Jansson L, Welsh M. Impaired glucose homeostasis in Shb-/- mice. J Endocrinol 2009, 203:271-9. 10.1677/JOE-09-0198, 19696098.
-
(2009)
J Endocrinol
, vol.203
, pp. 271-279
-
-
Akerblom, B.1
Barg, S.2
Calounova, G.3
Mokhtari, D.4
Jansson, L.5
Welsh, M.6
-
30
-
-
77955298871
-
The Src Homology 2 Domain-Containing Adapter Protein B (SHB) Regulates Mouse Oocyte Maturation
-
10.1371/journal.pone.0011155, 2886836, 20585392
-
Calnouva GL, Gabriel, Zhang, Xiao-Qun, Liu, Kui, Godsen, Roger, Welsh, Michael. The Src Homology 2 Domain-Containing Adapter Protein B (SHB) Regulates Mouse Oocyte Maturation. PLoS one 2010, 5:e11155. 10.1371/journal.pone.0011155, 2886836, 20585392.
-
(2010)
PLoS one
, vol.5
-
-
Calnouva, G.L.1
Gabriel2
Zhang3
Xiao-Qun4
Liu5
Kui6
Godsen7
Roger8
Welsh9
Michael10
-
31
-
-
0029760277
-
Apoptosis of NIH3T3 cells overexpressing the Src homology 2 domain protein Shb
-
Karlsson T, Welsh M. Apoptosis of NIH3T3 cells overexpressing the Src homology 2 domain protein Shb. Oncogene 1996, 13:955-61.
-
(1996)
Oncogene
, vol.13
, pp. 955-961
-
-
Karlsson, T.1
Welsh, M.2
-
32
-
-
27644546643
-
The Rb1 fraction of ginseng elicits a balanced Th1 and Th2 immune response
-
10.1016/j.vaccine.2005.04.007, 16286158
-
Rivera E, Pettersson Ekholm F, Inganas M, Paulie S, Gronvik KO. The Rb1 fraction of ginseng elicits a balanced Th1 and Th2 immune response. Vaccine 2005, 23:5411-9. 10.1016/j.vaccine.2005.04.007, 16286158.
-
(2005)
Vaccine
, vol.23
, pp. 5411-5419
-
-
Rivera, E.1
Pettersson Ekholm, F.2
Inganas, M.3
Paulie, S.4
Gronvik, K.O.5
-
33
-
-
0028859281
-
Selective requirement for MAP kinase activation in thymocyte differentiation
-
10.1038/373620a0, 7854419
-
Alberola-Ila J, Forbush KA, Seger R, Krebs EG, Perlmutter RM. Selective requirement for MAP kinase activation in thymocyte differentiation. Nature 1995, 373:620-3. 10.1038/373620a0, 7854419.
-
(1995)
Nature
, vol.373
, pp. 620-623
-
-
Alberola-Ila, J.1
Forbush, K.A.2
Seger, R.3
Krebs, E.G.4
Perlmutter, R.M.5
-
34
-
-
17144458301
-
Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice
-
10.1126/science.286.5443.1374, 10558995
-
Pages G, Guerin S, Grall D, Bonino F, Smith A, Anjuere F, Auberger P, Pouyssegur J. Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice. Science 1999, 286:1374-7. 10.1126/science.286.5443.1374, 10558995.
-
(1999)
Science
, vol.286
, pp. 1374-1377
-
-
Pages, G.1
Guerin, S.2
Grall, D.3
Bonino, F.4
Smith, A.5
Anjuere, F.6
Auberger, P.7
Pouyssegur, J.8
-
35
-
-
0023119089
-
Cell kinetics in the fetal mouse thymus: precursor cell input, proliferation, and emigration
-
Jotereau F, Heuze F, Salomon-Vie V, Gascan H. Cell kinetics in the fetal mouse thymus: precursor cell input, proliferation, and emigration. J Immunol 1987, 138:1026-30.
-
(1987)
J Immunol
, vol.138
, pp. 1026-1030
-
-
Jotereau, F.1
Heuze, F.2
Salomon-Vie, V.3
Gascan, H.4
-
36
-
-
0024109960
-
Thymocytes expressing CD8 differentiate into CD4+ cells following intrathymic injection
-
10.1073/pnas.85.22.8633, 282513, 3141930
-
Nikolic-Zugic J, Bevan MJ. Thymocytes expressing CD8 differentiate into CD4+ cells following intrathymic injection. Proc Natl Acad Sci USA 1988, 85:8633-7. 10.1073/pnas.85.22.8633, 282513, 3141930.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 8633-8637
-
-
Nikolic-Zugic, J.1
Bevan, M.J.2
-
37
-
-
0011156716
-
Intrathymic maturation of murine T lymphocytes from CD8+ precursors
-
10.1073/pnas.86.19.7542, 298101, 2508090
-
Guidos CJ, Weissman IL, Adkins B. Intrathymic maturation of murine T lymphocytes from CD8+ precursors. Proc Natl Acad Sci USA 1989, 86:7542-6. 10.1073/pnas.86.19.7542, 298101, 2508090.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 7542-7546
-
-
Guidos, C.J.1
Weissman, I.L.2
Adkins, B.3
-
38
-
-
0021346701
-
Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway
-
10.1073/pnas.81.5.1509, 344866, 6231642
-
Meuer SC, Hussey RE, Cantrell DA, Hodgdon JC, Schlossman SF, Smith KA, Reinherz EL. Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway. Proc Natl Acad Sci USA 1984, 81:1509-13. 10.1073/pnas.81.5.1509, 344866, 6231642.
-
(1984)
Proc Natl Acad Sci USA
, vol.81
, pp. 1509-1513
-
-
Meuer, S.C.1
Hussey, R.E.2
Cantrell, D.A.3
Hodgdon, J.C.4
Schlossman, S.F.5
Smith, K.A.6
Reinherz, E.L.7
-
39
-
-
0029847368
-
Functional diversity of helper T lymphocytes
-
10.1038/383787a0, 8893001
-
Abbas AK, Murphy KM, Sher A. Functional diversity of helper T lymphocytes. Nature 1996, 383:787-93. 10.1038/383787a0, 8893001.
-
(1996)
Nature
, vol.383
, pp. 787-793
-
-
Abbas, A.K.1
Murphy, K.M.2
Sher, A.3
-
40
-
-
0037077094
-
Induction of T helper type 2 immunity by a point mutation in the LAT adaptor
-
10.1126/science.1069057, 12065839
-
Aguado E, Richelme S, Nunez-Cruz S, Miazek A, Mura AM, Richelme M, Guo XJ, Sainty D, He HT, Malissen B, et al. Induction of T helper type 2 immunity by a point mutation in the LAT adaptor. Science 2002, 296:2036-40. 10.1126/science.1069057, 12065839.
-
(2002)
Science
, vol.296
, pp. 2036-2040
-
-
Aguado, E.1
Richelme, S.2
Nunez-Cruz, S.3
Miazek, A.4
Mura, A.M.5
Richelme, M.6
Guo, X.J.7
Sainty, D.8
He, H.T.9
Malissen, B.10
-
41
-
-
0027262235
-
Control of lymphocyte recirculation in man. I. Differential regulation of the peripheral lymph node homing receptor L-selectin on T cells during the virgin to memory cell transition
-
Picker LJ, Treer JR, Ferguson-Darnell B, Collins PA, Buck D, Terstappen LW. Control of lymphocyte recirculation in man. I. Differential regulation of the peripheral lymph node homing receptor L-selectin on T cells during the virgin to memory cell transition. J Immunol 1993, 150:1105-21.
-
(1993)
J Immunol
, vol.150
, pp. 1105-1121
-
-
Picker, L.J.1
Treer, J.R.2
Ferguson-Darnell, B.3
Collins, P.A.4
Buck, D.5
Terstappen, L.W.6
-
42
-
-
0029076926
-
Expression in vivo of CD45RA, CD45RB and CD44 on T cell receptor-transgenic CD8+ T cells following immunization
-
10.1002/eji.1830250640, 7542202
-
Pihlgren M, Lightstone L, Mamalaki C, Rimon G, Kioussis D, Marvel J. Expression in vivo of CD45RA, CD45RB and CD44 on T cell receptor-transgenic CD8+ T cells following immunization. Eur J Immunol 1995, 25:1755-9. 10.1002/eji.1830250640, 7542202.
-
(1995)
Eur J Immunol
, vol.25
, pp. 1755-1759
-
-
Pihlgren, M.1
Lightstone, L.2
Mamalaki, C.3
Rimon, G.4
Kioussis, D.5
Marvel, J.6
-
43
-
-
0030810155
-
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
-
10.1016/S0092-8674(00)80240-8, 9160750
-
Zheng W, Flavell RA. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 1997, 89:587-96. 10.1016/S0092-8674(00)80240-8, 9160750.
-
(1997)
Cell
, vol.89
, pp. 587-596
-
-
Zheng, W.1
Flavell, R.A.2
-
44
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
10.1016/S0092-8674(00)80702-3, 10761931
-
Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 2000, 100:655-69. 10.1016/S0092-8674(00)80702-3, 10761931.
-
(2000)
Cell
, vol.100
, pp. 655-669
-
-
Szabo, S.J.1
Kim, S.T.2
Costa, G.L.3
Zhang, X.4
Fathman, C.G.5
Glimcher, L.H.6
-
45
-
-
2342475200
-
T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression
-
10.1371/journal.pbio.0000053, 261890, 14624253
-
Roose JP, Diehn M, Tomlinson MG, Lin J, Alizadeh AA, Botstein D, Brown PO, Weiss A. T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression. PLoS Biol 2003, 1:E53. 10.1371/journal.pbio.0000053, 261890, 14624253.
-
(2003)
PLoS Biol
, vol.1
-
-
Roose, J.P.1
Diehn, M.2
Tomlinson, M.G.3
Lin, J.4
Alizadeh, A.A.5
Botstein, D.6
Brown, P.O.7
Weiss, A.8
-
46
-
-
33947721625
-
MiR-181a is an intrinsic modulator of T cell sensitivity and selection
-
10.1016/j.cell.2007.03.008, 17382377
-
Li QJ, Chau J, Ebert PJ, Sylvester G, Min H, Liu G, Braich R, Manoharan M, Soutschek J, Skare P, et al. miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell 2007, 129:147-61. 10.1016/j.cell.2007.03.008, 17382377.
-
(2007)
Cell
, vol.129
, pp. 147-161
-
-
Li, Q.J.1
Chau, J.2
Ebert, P.J.3
Sylvester, G.4
Min, H.5
Liu, G.6
Braich, R.7
Manoharan, M.8
Soutschek, J.9
Skare, P.10
-
47
-
-
68649087416
-
Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor
-
10.1016/j.immuni.2009.05.013, 19682930
-
Mingueneau M, Roncagalli R, Gregoire C, Kissenpfennig A, Miazek A, Archambaud C, Wang Y, Perrin P, Bertosio E, Sansoni A, et al. Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor. Immunity 2009, 31:197-208. 10.1016/j.immuni.2009.05.013, 19682930.
-
(2009)
Immunity
, vol.31
, pp. 197-208
-
-
Mingueneau, M.1
Roncagalli, R.2
Gregoire, C.3
Kissenpfennig, A.4
Miazek, A.5
Archambaud, C.6
Wang, Y.7
Perrin, P.8
Bertosio, E.9
Sansoni, A.10
-
48
-
-
0032438114
-
Altered thymic positive selection and intracellular signals in Cbl-deficient mice
-
10.1073/pnas.95.26.15547, 28080, 9861006
-
Naramura M, Kole HK, Hu RJ, Gu H. Altered thymic positive selection and intracellular signals in Cbl-deficient mice. Proc Natl Acad Sci USA 1998, 95:15547-52. 10.1073/pnas.95.26.15547, 28080, 9861006.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 15547-15552
-
-
Naramura, M.1
Kole, H.K.2
Hu, R.J.3
Gu, H.4
-
49
-
-
0022640843
-
Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
-
Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986, 136:2348-57.
-
(1986)
J Immunol
, vol.136
, pp. 2348-2357
-
-
Mosmann, T.R.1
Cherwinski, H.2
Bond, M.W.3
Giedlin, M.A.4
Coffman, R.L.5
-
50
-
-
23744484121
-
Impaired IL-4 and c-Maf expression and enhanced Th1-cell development in Vav1-deficient mice
-
10.1182/blood-2004-10-4074, 1895205, 15845902
-
Tanaka Y, So T, Lebedeva S, Croft M, Altman A. Impaired IL-4 and c-Maf expression and enhanced Th1-cell development in Vav1-deficient mice. Blood 2005, 106:1286-95. 10.1182/blood-2004-10-4074, 1895205, 15845902.
-
(2005)
Blood
, vol.106
, pp. 1286-1295
-
-
Tanaka, Y.1
So, T.2
Lebedeva, S.3
Croft, M.4
Altman, A.5
-
51
-
-
0034176032
-
Vav synergizes with protein kinase C theta to mediate IL-4 gene expression in response to CD28 costimulation in T cells
-
Hehner SP, Li-Weber M, Giaisi M, Droge W, Krammer PH, Schmitz ML. Vav synergizes with protein kinase C theta to mediate IL-4 gene expression in response to CD28 costimulation in T cells. J Immunol 2000, 164:3829-36.
-
(2000)
J Immunol
, vol.164
, pp. 3829-3836
-
-
Hehner, S.P.1
Li-Weber, M.2
Giaisi, M.3
Droge, W.4
Krammer, P.H.5
Schmitz, M.L.6
-
52
-
-
0029788387
-
Cytokine transcriptional events during helper T cell subset differentiation
-
10.1084/jem.184.2.397, 2192740, 8760793
-
Lederer JA, Perez VL, DesRoches L, Kim SM, Abbas AK, Lichtman AH. Cytokine transcriptional events during helper T cell subset differentiation. J Exp Med 1996, 184:397-406. 10.1084/jem.184.2.397, 2192740, 8760793.
-
(1996)
J Exp Med
, vol.184
, pp. 397-406
-
-
Lederer, J.A.1
Perez, V.L.2
DesRoches, L.3
Kim, S.M.4
Abbas, A.K.5
Lichtman, A.H.6
-
53
-
-
0038638583
-
An epigenetic view of helper T cell differentiation
-
10.1038/ni0703-616, 12830136
-
Ansel KM, Lee DU, Rao A. An epigenetic view of helper T cell differentiation. Nat Immunol 2003, 4:616-23. 10.1038/ni0703-616, 12830136.
-
(2003)
Nat Immunol
, vol.4
, pp. 616-623
-
-
Ansel, K.M.1
Lee, D.U.2
Rao, A.3
-
54
-
-
10344234192
-
Th2-specific chromatin remodeling and enhancer activity in the Th2 cytokine locus control region
-
10.1016/j.immuni.2004.10.015, 15589174
-
Fields PE, Lee GR, Kim ST, Bartsevich VV, Flavell RA. Th2-specific chromatin remodeling and enhancer activity in the Th2 cytokine locus control region. Immunity 2004, 21:865-76. 10.1016/j.immuni.2004.10.015, 15589174.
-
(2004)
Immunity
, vol.21
, pp. 865-876
-
-
Fields, P.E.1
Lee, G.R.2
Kim, S.T.3
Bartsevich, V.V.4
Flavell, R.A.5
-
55
-
-
0036667345
-
In TH2 cells the Il4 gene has a series of accessibility states associated with distinctive probabilities of IL-4 production
-
10.1073/pnas.162360199, 124993, 12149469
-
Guo L, Hu-Li J, Zhu J, Watson CJ, Difilippantonio MJ, Pannetier C, Paul WE. In TH2 cells the Il4 gene has a series of accessibility states associated with distinctive probabilities of IL-4 production. Proc Natl Acad Sci USA 2002, 99:10623-8. 10.1073/pnas.162360199, 124993, 12149469.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 10623-10628
-
-
Guo, L.1
Hu-Li, J.2
Zhu, J.3
Watson, C.J.4
Difilippantonio, M.J.5
Pannetier, C.6
Paul, W.E.7
-
56
-
-
0032143821
-
Helper T cell differentiation is controlled by the cell cycle
-
10.1016/S1074-7613(00)80605-6, 9729043
-
Bird JJ, Brown DR, Mullen AC, Moskowitz NH, Mahowald MA, Sider JR, Gajewski TF, Wang CR, Reiner SL. Helper T cell differentiation is controlled by the cell cycle. Immunity 1998, 9:229-37. 10.1016/S1074-7613(00)80605-6, 9729043.
-
(1998)
Immunity
, vol.9
, pp. 229-237
-
-
Bird, J.J.1
Brown, D.R.2
Mullen, A.C.3
Moskowitz, N.H.4
Mahowald, M.A.5
Sider, J.R.6
Gajewski, T.F.7
Wang, C.R.8
Reiner, S.L.9
|