메뉴 건너뛰기




Volumn 650, Issue 2-3, 2011, Pages 629-638

Enhanced airway smooth muscle cell thromboxane receptor signaling via activation of JNK MAPK and extracellular calcium influx

Author keywords

Airway hyperresponsiveness; Calcium influx; JNK MAPK; Signaling; TP receptor

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; CALCIUM; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NIFEDIPINE; STRESS ACTIVATED PROTEIN KINASE; THROMBOXANE; THROMBOXANE RECEPTOR;

EID: 78651072718     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.10.038     Document Type: Article
Times cited : (15)

References (53)
  • 1
    • 0028884033 scopus 로고
    • PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
    • D.R. Alessi, A. Cuenda, P. Cohen, D.T. Dudley, and A.R. Saltiel PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo J. Biol. Chem. 270 1995 27489 27494
    • (1995) J. Biol. Chem. , vol.270 , pp. 27489-27494
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3    Dudley, D.T.4    Saltiel, A.R.5
  • 2
    • 3042601105 scopus 로고    scopus 로고
    • Organ culture: A new model for vascular endothelium dysfunction
    • R. Alm, L. Edvinsson, and M. Malmsjo Organ culture: a new model for vascular endothelium dysfunction BMC Cardiovasc. Disord. 2 2002 8
    • (2002) BMC Cardiovasc. Disord. , vol.2 , pp. 8
    • Alm, R.1    Edvinsson, L.2    Malmsjo, M.3
  • 3
    • 0031871552 scopus 로고    scopus 로고
    • Cytokines induce airway smooth muscle cell hyperresponsiveness to contractile agonists
    • Y. Amrani, and R.A. Panettieri Jr. Cytokines induce airway smooth muscle cell hyperresponsiveness to contractile agonists Thorax 53 1998 713 716
    • (1998) Thorax , vol.53 , pp. 713-716
    • Amrani, Y.1    Panettieri Jr., R.A.2
  • 6
    • 0024322052 scopus 로고
    • Characterization of contractile prostanoid receptors on human airway smooth muscle
    • C.L. Armour, P.R. Johnson, M.L. Alfredson, and J.L. Black Characterization of contractile prostanoid receptors on human airway smooth muscle Eur. J. Pharmacol. 165 1989 215 222
    • (1989) Eur. J. Pharmacol. , vol.165 , pp. 215-222
    • Armour, C.L.1    Johnson, P.R.2    Alfredson, M.L.3    Black, J.L.4
  • 7
    • 33846114713 scopus 로고    scopus 로고
    • Contractility and Ca2+ signaling of smooth muscle cells in different generations of mouse airways
    • Y. Bai, M. Zhang, and M.J. Sanderson Contractility and Ca2+ signaling of smooth muscle cells in different generations of mouse airways Am. J. Respir. Cell Mol. Biol. 36 2007 122 130
    • (2007) Am. J. Respir. Cell Mol. Biol. , vol.36 , pp. 122-130
    • Bai, Y.1    Zhang, M.2    Sanderson, M.J.3
  • 8
    • 0035126782 scopus 로고    scopus 로고
    • Neurogenic inflammation in the airways
    • P.J. Barnes Neurogenic inflammation in the airways Respir. Physiol. 125 2001 145 154
    • (2001) Respir. Physiol. , vol.125 , pp. 145-154
    • Barnes, P.J.1
  • 9
    • 37549032063 scopus 로고    scopus 로고
    • Activation of thromboxane receptor upregulates interleukin (IL)-1beta-induced VCAM-1 expression through JNK signaling
    • H. Bayat, S. Xu, D. Pimentel, R.A. Cohen, and B. Jiang Activation of thromboxane receptor upregulates interleukin (IL)-1beta-induced VCAM-1 expression through JNK signaling Arterioscler. Thromb. Vasc. Biol. 28 2008 127 134
    • (2008) Arterioscler. Thromb. Vasc. Biol. , vol.28 , pp. 127-134
    • Bayat, H.1    Xu, S.2    Pimentel, D.3    Cohen, R.A.4    Jiang, B.5
  • 11
    • 16444384786 scopus 로고    scopus 로고
    • Thromboxane prostanoid receptor signals through Gi protein to rapidly activate extracellular signal-regulated kinase in human airways
    • S. Citro, S. Ravasi, G.E. Rovati, and V. Capra Thromboxane prostanoid receptor signals through Gi protein to rapidly activate extracellular signal-regulated kinase in human airways Am. J. Respir. Cell Mol. Biol. 32 2005 326 333
    • (2005) Am. J. Respir. Cell Mol. Biol. , vol.32 , pp. 326-333
    • Citro, S.1    Ravasi, S.2    Rovati, G.E.3    Capra, V.4
  • 12
    • 33748046456 scopus 로고    scopus 로고
    • Mechanisms of airway hyperresponsiveness
    • D.W. Cockcroft, and B.E. Davis Mechanisms of airway hyperresponsiveness J. Allergy Clin. Immunol. 118 2006 551 559 quiz 560-551
    • (2006) J. Allergy Clin. Immunol. , vol.118 , pp. 551-559
    • Cockcroft, D.W.1    Davis, B.E.2
  • 13
    • 0028988138 scopus 로고
    • SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
    • A. Cuenda, J. Rouse, Y.N. Doza, R. Meier, P. Cohen, T.F. Gallagher, P.R. Young, and J.C. Lee SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1 FEBS Lett. 364 1995 229 233
    • (1995) FEBS Lett. , vol.364 , pp. 229-233
    • Cuenda, A.1    Rouse, J.2    Doza, Y.N.3    Meier, R.4    Cohen, P.5    Gallagher, T.F.6    Young, P.R.7    Lee, J.C.8
  • 14
    • 14444268051 scopus 로고    scopus 로고
    • Enhanced thromboxane biosynthesis in patients with chronic obstructive pulmonary disease
    • The Chronic Obstructive Bronchitis and Haemostasis Study Group
    • G. Davi, S. Basili, M. Vieri, F. Cipollone, S. Santarone, C. Alessandri, P. Gazzaniga, C. Cordova, and F. Violi Enhanced thromboxane biosynthesis in patients with chronic obstructive pulmonary disease. The Chronic Obstructive Bronchitis and Haemostasis Study Group Am. J. Respir. Crit. Care Med. 156 1997 1794 1799
    • (1997) Am. J. Respir. Crit. Care Med. , vol.156 , pp. 1794-1799
    • Davi, G.1    Basili, S.2    Vieri, M.3    Cipollone, F.4    Santarone, S.5    Alessandri, C.6    Gazzaniga, P.7    Cordova, C.8    Violi, F.9
  • 15
    • 0030614835 scopus 로고    scopus 로고
    • Thromboxane A2 and related prostaglandins in airways
    • P. Devillier, and G. Bessard Thromboxane A2 and related prostaglandins in airways Fundam. Clin. Pharmacol. 11 1997 2 18
    • (1997) Fundam. Clin. Pharmacol. , vol.11 , pp. 2-18
    • Devillier, P.1    Bessard, G.2
  • 18
    • 33744830286 scopus 로고    scopus 로고
    • Targeting mitogen-activated protein kinases for asthma
    • W. Duan, and W.S. Wong Targeting mitogen-activated protein kinases for asthma Curr. Drug Targets 7 2006 691 698
    • (2006) Curr. Drug Targets , vol.7 , pp. 691-698
    • Duan, W.1    Wong, W.S.2
  • 19
    • 2442712697 scopus 로고    scopus 로고
    • Anti-inflammatory effects of mitogen-activated protein kinase kinase inhibitor U0126 in an asthma mouse model
    • W. Duan, J.H. Chan, C.H. Wong, B.P. Leung, and W.S. Wong Anti-inflammatory effects of mitogen-activated protein kinase kinase inhibitor U0126 in an asthma mouse model J. Immunol. 172 2004 7053 7059
    • (2004) J. Immunol. , vol.172 , pp. 7053-7059
    • Duan, W.1    Chan, J.H.2    Wong, C.H.3    Leung, B.P.4    Wong, W.S.5
  • 22
    • 33646184810 scopus 로고    scopus 로고
    • Smoking particles enhance endothelin A and endothelin B receptor-mediated contractions by enhancing translation in rat bronchi
    • B.W. Granstrom, C.B. Xu, E. Nilsson, P. Vikman, and L. Edvinsson Smoking particles enhance endothelin A and endothelin B receptor-mediated contractions by enhancing translation in rat bronchi BMC Pulm. Med. 6 2006 6
    • (2006) BMC Pulm. Med. , vol.6 , pp. 6
    • Granstrom, B.W.1    Xu, C.B.2    Nilsson, E.3    Vikman, P.4    Edvinsson, L.5
  • 23
    • 0016748441 scopus 로고
    • Thromboxanes: A new group of biologically active compounds derived from prostaglandin endoperoxides
    • M. Hamberg, J. Svensson, and B. Samuelsson Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides Proc. Natl Acad. Sci. USA 72 1975 2994 2998
    • (1975) Proc. Natl Acad. Sci. USA , vol.72 , pp. 2994-2998
    • Hamberg, M.1    Svensson, J.2    Samuelsson, B.3
  • 24
    • 20144377095 scopus 로고    scopus 로고
    • In vitro and in vivo pharmacological characterization of BM-613 [N-n-pentyl-N′-[2-(4′-methylphenylamino)-5-nitrobenzenesulfonyl] urea], a novel dual thromboxane synthase inhibitor and thromboxane receptor antagonist
    • J. Hanson, S. Rolin, D. Reynaud, N. Qiao, L.P. Kelley, H.M. Reid, F. Valentin, J. Tippins, B.T. Kinsella, B. Masereel, C. Pace-Asciak, B. Pirotte, and J.M. Dogne In vitro and in vivo pharmacological characterization of BM-613 [N-n-pentyl-N′-[2-(4′-methylphenylamino)-5-nitrobenzenesulfonyl] urea], a novel dual thromboxane synthase inhibitor and thromboxane receptor antagonist J. Pharmacol. Exp. Ther. 313 2005 293 301
    • (2005) J. Pharmacol. Exp. Ther. , vol.313 , pp. 293-301
    • Hanson, J.1    Rolin, S.2    Reynaud, D.3    Qiao, N.4    Kelley, L.P.5    Reid, H.M.6    Valentin, F.7    Tippins, J.8    Kinsella, B.T.9    Masereel, B.10    Pace-Asciak, C.11    Pirotte, B.12    Dogne, J.M.13
  • 25
    • 0020663886 scopus 로고
    • Mechanical properties of rat cerebral arteries as studied by a sensitive device for recording of mechanical activity in isolated small blood vessels
    • E.D. Hogestatt, K.E. Andersson, and L. Edvinsson Mechanical properties of rat cerebral arteries as studied by a sensitive device for recording of mechanical activity in isolated small blood vessels Acta Physiol. Scand. 117 1983 49 61
    • (1983) Acta Physiol. Scand. , vol.117 , pp. 49-61
    • Hogestatt, E.D.1    Andersson, K.E.2    Edvinsson, L.3
  • 26
    • 39449134944 scopus 로고    scopus 로고
    • Effects of KP-496, a novel dual antagonist at the cysteinyl leukotriene receptor 1 and the thromboxane A(2) receptor, on airway obstruction in guinea pigs
    • M. Ishimura, M. Suda, K. Morizumi, S. Kataoka, T. Maeda, S. Kurokawa, and Y. Hiyama Effects of KP-496, a novel dual antagonist at the cysteinyl leukotriene receptor 1 and the thromboxane A(2) receptor, on airway obstruction in guinea pigs Br. J. Pharmacol. 153 2008 669 675
    • (2008) Br. J. Pharmacol. , vol.153 , pp. 669-675
    • Ishimura, M.1    Suda, M.2    Morizumi, K.3    Kataoka, S.4    Maeda, T.5    Kurokawa, S.6    Hiyama, Y.7
  • 27
    • 0024164652 scopus 로고
    • Thromboxane A2 production in allergen-induced immediate and late asthmatic responses. Its possible role in inducing the late response
    • I. Iwamoto, C. Ra, T. Sato, H. Tomioka, and S. Yoshida Thromboxane A2 production in allergen-induced immediate and late asthmatic responses. Its possible role in inducing the late response J. Asthma 25 1988 117 124
    • (1988) J. Asthma , vol.25 , pp. 117-124
    • Iwamoto, I.1    Ra, C.2    Sato, T.3    Tomioka, H.4    Yoshida, S.5
  • 28
    • 0026874477 scopus 로고
    • Effect of an inhaled thromboxane mimetic (U46619) on airway function in human subjects
    • G.L. Jones, H.G. Saroea, R.M. Watson, and P.M. O'Byrne Effect of an inhaled thromboxane mimetic (U46619) on airway function in human subjects Am. Rev. Respir. Dis. 145 1992 1270 1274
    • (1992) Am. Rev. Respir. Dis. , vol.145 , pp. 1270-1274
    • Jones, G.L.1    Saroea, H.G.2    Watson, R.M.3    O'Byrne, P.M.4
  • 30
    • 85047683217 scopus 로고    scopus 로고
    • Thromboxane A2 signalling in humans: A 'Tail' of two receptors
    • B.T. Kinsella Thromboxane A2 signalling in humans: a 'Tail' of two receptors Biochem. Soc. Trans. 29 2001 641 654
    • (2001) Biochem. Soc. Trans. , vol.29 , pp. 641-654
    • Kinsella, B.T.1
  • 31
    • 14644390846 scopus 로고    scopus 로고
    • The isoprostane 8-iso-PGF2alpha suppresses monocyte adhesion to human microvascular endothelial cells via two independent mechanisms
    • A. Kumar, E. Kingdon, and J. Norman The isoprostane 8-iso-PGF2alpha suppresses monocyte adhesion to human microvascular endothelial cells via two independent mechanisms FASEB J. 19 2005 443 445
    • (2005) FASEB J. , vol.19 , pp. 443-445
    • Kumar, A.1    Kingdon, E.2    Norman, J.3
  • 32
    • 77951177701 scopus 로고    scopus 로고
    • Up-regulation of bradykinin receptors in rat bronchia via IkappaB Kinase-mediated inflammatory signaling pathway
    • Y. Lei, Y. Zhang, Y. Cao, L. Edvinsson, and C.B. Xu Up-regulation of bradykinin receptors in rat bronchia via IkappaB Kinase-mediated inflammatory signaling pathway Eur. J. Pharmacol. 634 2010 149 161
    • (2010) Eur. J. Pharmacol. , vol.634 , pp. 149-161
    • Lei, Y.1    Zhang, Y.2    Cao, Y.3    Edvinsson, L.4    Xu, C.B.5
  • 33
    • 0031900740 scopus 로고    scopus 로고
    • Signal transduction through MAP kinase cascades
    • T.S. Lewis, P.S. Shapiro, and N.G. Ahn Signal transduction through MAP kinase cascades Adv. Cancer Res. 74 1998 49 139
    • (1998) Adv. Cancer Res. , vol.74 , pp. 49-139
    • Lewis, T.S.1    Shapiro, P.S.2    Ahn, N.G.3
  • 35
    • 0025999792 scopus 로고
    • BAY u3405, a potent and selective thromboxane A2 receptor antagonist on airway smooth muscle in vitro
    • M.G. McKenniff, P. Norman, N.J. Cuthbert, and P.J. Gardiner BAY u3405, a potent and selective thromboxane A2 receptor antagonist on airway smooth muscle in vitro Br. J. Pharmacol. 104 1991 585 590
    • (1991) Br. J. Pharmacol. , vol.104 , pp. 585-590
    • McKenniff, M.G.1    Norman, P.2    Cuthbert, N.J.3    Gardiner, P.J.4
  • 37
    • 0035963041 scopus 로고    scopus 로고
    • Thromboxane A(2) receptor mediated activation of the mitogen activated protein kinase cascades in human uterine smooth muscle cells
    • S.M. Miggin, and B.T. Kinsella Thromboxane A(2) receptor mediated activation of the mitogen activated protein kinase cascades in human uterine smooth muscle cells Biochim. Biophys. Acta 1539 2001 147 162
    • (2001) Biochim. Biophys. Acta , vol.1539 , pp. 147-162
    • Miggin, S.M.1    Kinsella, B.T.2
  • 39
    • 14944386613 scopus 로고    scopus 로고
    • Potential role of c-Jun NH2-terminal kinase in allergic airway inflammation and remodelling: Effects of SP600125
    • P. Nath, P. Eynott, S.Y. Leung, I.M. Adcock, B.L. Bennett, and K.F. Chung Potential role of c-Jun NH2-terminal kinase in allergic airway inflammation and remodelling: effects of SP600125 Eur. J. Pharmacol. 506 2005 273 283
    • (2005) Eur. J. Pharmacol. , vol.506 , pp. 273-283
    • Nath, P.1    Eynott, P.2    Leung, S.Y.3    Adcock, I.M.4    Bennett, B.L.5    Chung, K.F.6
  • 40
    • 0037336954 scopus 로고    scopus 로고
    • Airway hyperresponsiveness
    • P.M. O'Byrne, and M.D. Inman Airway hyperresponsiveness Chest 123 2003 411S 416S
    • (2003) Chest , vol.123
    • O'Byrne, P.M.1    Inman, M.D.2
  • 44
    • 0032446729 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease is associated with an increase in urinary levels of isoprostane F2alpha-III, an index of oxidant stress
    • D. Pratico, S. Basili, M. Vieri, C. Cordova, F. Violi, and G.A. Fitzgerald Chronic obstructive pulmonary disease is associated with an increase in urinary levels of isoprostane F2alpha-III, an index of oxidant stress Am. J. Respir. Crit. Care Med. 158 1998 1709 1714
    • (1998) Am. J. Respir. Crit. Care Med. , vol.158 , pp. 1709-1714
    • Pratico, D.1    Basili, S.2    Vieri, M.3    Cordova, C.4    Violi, F.5    Fitzgerald, G.A.6
  • 45
    • 0022357492 scopus 로고
    • Pulmonary synthesis, release, and metabolism of prostaglandins
    • C. Robinson, C.C. Hardy, and S.T. Holgate Pulmonary synthesis, release, and metabolism of prostaglandins J. Allergy Clin. Immunol. 76 1985 265 271
    • (1985) J. Allergy Clin. Immunol. , vol.76 , pp. 265-271
    • Robinson, C.1    Hardy, C.C.2    Holgate, S.T.3
  • 46
    • 0032201547 scopus 로고    scopus 로고
    • Cell signal transduction through the mitogen-activated protein kinase pathway
    • H.W. Schnaper Cell signal transduction through the mitogen-activated protein kinase pathway Pediatr. Nephrol. 12 1998 790 795
    • (1998) Pediatr. Nephrol. , vol.12 , pp. 790-795
    • Schnaper, H.W.1
  • 48
    • 0031932309 scopus 로고    scopus 로고
    • Role of extracellular Ca++ influx via L-type and non-L-type Ca++ channels in thromboxane A2 receptor-mediated contraction in rat aorta
    • M. Tosun, R.J. Paul, and R.M. Rapoport Role of extracellular Ca++ influx via L-type and non-L-type Ca++ channels in thromboxane A2 receptor-mediated contraction in rat aorta J. Pharmacol. Exp. Ther. 284 1998 921 928
    • (1998) J. Pharmacol. Exp. Ther. , vol.284 , pp. 921-928
    • Tosun, M.1    Paul, R.J.2    Rapoport, R.M.3
  • 49
    • 0028824070 scopus 로고
    • Time-course of antigen-induced airway inflammation in the guinea-pig and its relationship to airway hyperresponsiveness
    • S. Underwood, M. Foster, D. Raeburn, S. Bottoms, and J.A. Karlsson Time-course of antigen-induced airway inflammation in the guinea-pig and its relationship to airway hyperresponsiveness Eur. Respir. J. 8 1995 2104 2113
    • (1995) Eur. Respir. J. , vol.8 , pp. 2104-2113
    • Underwood, S.1    Foster, M.2    Raeburn, D.3    Bottoms, S.4    Karlsson, J.A.5
  • 50
    • 0031017337 scopus 로고    scopus 로고
    • Arachidonic acid metabolites: Mediators of inflammation in asthma
    • S.E. Wenzel Arachidonic acid metabolites: mediators of inflammation in asthma Pharmacotherapy 17 1997 3S 12S
    • (1997) Pharmacotherapy , vol.17
    • Wenzel, S.E.1
  • 51
    • 0024548854 scopus 로고
    • Spectrum of prostanoid release after bronchoalveolar allergen challenge in atopic asthmatics and in control groups. An alteration in the ratio of bronchoconstrictive to bronchoprotective mediators
    • S.E. Wenzel, J.Y. Westcott, H.R. Smith, and G.L. Larsen Spectrum of prostanoid release after bronchoalveolar allergen challenge in atopic asthmatics and in control groups. An alteration in the ratio of bronchoconstrictive to bronchoprotective mediators Am. Rev. Respir. Dis. 139 1989 450 457
    • (1989) Am. Rev. Respir. Dis. , vol.139 , pp. 450-457
    • Wenzel, S.E.1    Westcott, J.Y.2    Smith, H.R.3    Larsen, G.L.4
  • 52
    • 34247842915 scopus 로고    scopus 로고
    • IL-1beta induces murine airway 5-HT2A receptor hyperresponsiveness via a non-transcriptional MAPK-dependent mechanism
    • Y. Zhang, L.O. Cardell, and M. Adner IL-1beta induces murine airway 5-HT2A receptor hyperresponsiveness via a non-transcriptional MAPK-dependent mechanism Respir. Res. 8 2007 29
    • (2007) Respir. Res. , vol.8 , pp. 29
    • Zhang, Y.1    Cardell, L.O.2    Adner, M.3
  • 53
    • 50649118327 scopus 로고    scopus 로고
    • Transcriptional down-regulation of thromboxane A(2) receptor expression via activation of MAPK ERK1/2, p38/NF-kappaB pathways
    • W. Zhang, Y. Zhang, L. Edvinsson, and C.B. Xu Transcriptional down-regulation of thromboxane A(2) receptor expression via activation of MAPK ERK1/2, p38/NF-kappaB pathways J. Vasc. Res. 46 2009 162 174
    • (2009) J. Vasc. Res. , vol.46 , pp. 162-174
    • Zhang, W.1    Zhang, Y.2    Edvinsson, L.3    Xu, C.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.