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Volumn 46, Issue 2, 2009, Pages 162-174

Transcriptional down-regulation of thromboxane A2 receptor expression via activation of MAPK ERK1/2, p38/NF-κB pathways

Author keywords

Mesenteric artery; Rat; Thromboxane A2 receptors; Vascular diseases

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; DACTINOMYCIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN SYNTHASE; THROMBOXANE A2 RECEPTOR;

EID: 50649118327     PISSN: 10181172     EISSN: None     Source Type: Journal    
DOI: 10.1159/000153247     Document Type: Article
Times cited : (11)

References (60)
  • 1
    • 0032823306 scopus 로고    scopus 로고
    • Prostanoid receptors: Structures, properties, and functions
    • Narumiya S, Sugimoto Y, Ushikubi F: Prostanoid receptors: structures, properties, and functions. Physiol Rev 1999;79:1193-1226.
    • (1999) Physiol Rev , vol.79 , pp. 1193-1226
    • Narumiya, S.1    Sugimoto, Y.2    Ushikubi, F.3
  • 2
    • 0034931501 scopus 로고    scopus 로고
    • Genetic and pharmacological analysis of prostanoid receptor function
    • Narumiya S, FitzGerald GA: Genetic and pharmacological analysis of prostanoid receptor function. J Clin Invest 2001;108:25-30.
    • (2001) J Clin Invest , vol.108 , pp. 25-30
    • Narumiya, S.1    FitzGerald, G.A.2
  • 5
    • 0022302397 scopus 로고
    • The biological role of thromboxane A2 in the process of hemostasis and thrombosis; pharmacology and perspectives of therapeutical use of thromboxane synthetase inhibitors and receptor PGH2/TXA2 antagonists
    • Radomski M: The biological role of thromboxane A2 in the process of hemostasis and thrombosis; pharmacology and perspectives of therapeutical use of thromboxane synthetase inhibitors and receptor PGH2/TXA2 antagonists. Acta Physiol Pol 1985;36:153-164.
    • (1985) Acta Physiol Pol , vol.36 , pp. 153-164
    • Radomski, M.1
  • 8
    • 0035214283 scopus 로고    scopus 로고
    • 1 receptor antagonist losartan. Br J Pharmacol 2001;134:1385-1392.
    • 1 receptor antagonist losartan. Br J Pharmacol 2001;134:1385-1392.
  • 9
    • 0024952949 scopus 로고
    • Antihypertensive effect of thromboxane A2 receptor blockade in genetically hypertensive rats of the lyon strain
    • Geoffroy J, Benzoni D, Sassard J: Antihypertensive effect of thromboxane A2 receptor blockade in genetically hypertensive rats of the lyon strain. J Hypertens Suppl 1989;7:S272-S273.
    • (1989) J Hypertens Suppl , vol.7
    • Geoffroy, J.1    Benzoni, D.2    Sassard, J.3
  • 10
    • 0037155906 scopus 로고    scopus 로고
    • Transcription suppression of thromboxane receptor gene by peroxisome proliferator-activated receptor-gamma via an interaction with sp1 in vascular smooth muscle cells
    • Sugawara A, Uruno A, Kudo M, Ikeda Y, Sato K, Taniyama Y, Ito S, Takeuchi K: Transcription suppression of thromboxane receptor gene by peroxisome proliferator-activated receptor-gamma via an interaction with sp1 in vascular smooth muscle cells. J Biol Chem 2002;277:9676-9683.
    • (2002) J Biol Chem , vol.277 , pp. 9676-9683
    • Sugawara, A.1    Uruno, A.2    Kudo, M.3    Ikeda, Y.4    Sato, K.5    Taniyama, Y.6    Ito, S.7    Takeuchi, K.8
  • 11
    • 0242441549 scopus 로고    scopus 로고
    • Transcription suppression of thromboxane receptor gene expression by retinoids in vascular smooth muscle cells
    • Uruno A, Sugawara A, Kudo M, Sato M, Sato K, Ito S, Takeuchi K: Transcription suppression of thromboxane receptor gene expression by retinoids in vascular smooth muscle cells. Hypertens Res 2003;26:815-821.
    • (2003) Hypertens Res , vol.26 , pp. 815-821
    • Uruno, A.1    Sugawara, A.2    Kudo, M.3    Sato, M.4    Sato, K.5    Ito, S.6    Takeuchi, K.7
  • 12
    • 0026580751 scopus 로고
    • Growth factors downregulate vascular smooth muscle thromboxane receptors independent of cell growth
    • Dorn GW 2nd, Becker MW: Growth factors downregulate vascular smooth muscle thromboxane receptors independent of cell growth. Am J Physiol 1992;262:C927-C933.
    • (1992) Am J Physiol , vol.262
    • Dorn 2nd, G.W.1    Becker, M.W.2
  • 13
    • 0027336655 scopus 로고
    • Thromboxane A2/prostaglandin H2 receptors in streptozotocin-induced diabetes: Effects of insulin therapy in the rat
    • Morinelli TA, Tempel GE, Jaffa AA, Silva RH, Naka M, Folger W, Halushka PV: Thromboxane A2/prostaglandin H2 receptors in streptozotocin-induced diabetes: effects of insulin therapy in the rat. Prostaglandins 1993;45:427-438.
    • (1993) Prostaglandins , vol.45 , pp. 427-438
    • Morinelli, T.A.1    Tempel, G.E.2    Jaffa, A.A.3    Silva, R.H.4    Naka, M.5    Folger, W.6    Halushka, P.V.7
  • 14
    • 0028587194 scopus 로고
    • Reduced thromboxane receptor affinity and vasoconstrictor responses in placentae from diabetic pregnancies
    • Wilkes BM, Mento PF, Hollander AM: Reduced thromboxane receptor affinity and vasoconstrictor responses in placentae from diabetic pregnancies. Placenta 1994;15:845-855.
    • (1994) Placenta , vol.15 , pp. 845-855
    • Wilkes, B.M.1    Mento, P.F.2    Hollander, A.M.3
  • 15
    • 0032563713 scopus 로고    scopus 로고
    • Estrogen replacement suppresses a prostaglandin h synthase-dependent vasoconstrictor in rat mesenteric arteries
    • Davidge ST, Zhang Y: Estrogen replacement suppresses a prostaglandin h synthase-dependent vasoconstrictor in rat mesenteric arteries. Circ Res 1998;83:388-395.
    • (1998) Circ Res , vol.83 , pp. 388-395
    • Davidge, S.T.1    Zhang, Y.2
  • 16
    • 0027534090 scopus 로고
    • Smooth muscle cells and the pathogenesis of the lesions of atherosclerosis
    • Raines EW, Ross R: Smooth muscle cells and the pathogenesis of the lesions of atherosclerosis. Br Heart J 1993;69:S30-S37.
    • (1993) Br Heart J , vol.69
    • Raines, E.W.1    Ross, R.2
  • 17
    • 0029853692 scopus 로고    scopus 로고
    • Plasticity of contractile endothelin-B receptors in human arteries after organ culture
    • Adner M, Cantera L, Ehlert F, Nilsson L, Edvinsson L: Plasticity of contractile endothelin-B receptors in human arteries after organ culture. Br J Pharmacol 1996;119:1159-1166.
    • (1996) Br J Pharmacol , vol.119 , pp. 1159-1166
    • Adner, M.1    Cantera, L.2    Ehlert, F.3    Nilsson, L.4    Edvinsson, L.5
  • 19
    • 10644288499 scopus 로고    scopus 로고
    • Transcriptional up-regulation in expression of 5-hydroxytryptamine 2A and transcriptional down-regulation of angiotensin II type 1 receptors during organ culture of rat mesenteric artery
    • Luo G, Xu CB, Cao YX, Edvinsson L: Transcriptional up-regulation in expression of 5-hydroxytryptamine 2A and transcriptional down-regulation of angiotensin II type 1 receptors during organ culture of rat mesenteric artery. Basic Clin Pharmacol Toxicol 2004;95:280-287.
    • (2004) Basic Clin Pharmacol Toxicol , vol.95 , pp. 280-287
    • Luo, G.1    Xu, C.B.2    Cao, Y.X.3    Edvinsson, L.4
  • 20
    • 15944408437 scopus 로고    scopus 로고
    • Enhanced transcription of contractile 5-hydroxytryptamine 2A receptors via extracellular signal-regulated kinase 1/2 after organ culture of rat mesenteric artery
    • Cao YX, He LC, Xu CB, Luo GG, Edvinsson L: Enhanced transcription of contractile 5-hydroxytryptamine 2A receptors via extracellular signal-regulated kinase 1/2 after organ culture of rat mesenteric artery. Basic Clin Pharmacol Toxicol 2005;96:282-288.
    • (2005) Basic Clin Pharmacol Toxicol , vol.96 , pp. 282-288
    • Cao, Y.X.1    He, L.C.2    Xu, C.B.3    Luo, G.G.4    Edvinsson, L.5
  • 22
    • 0036727204 scopus 로고    scopus 로고
    • Protein kinase mediated upregulation of endothelin A, endothelin B and 5-hydroxytryptamine 1B/1D receptors during organ culture in rat basilar artery
    • Hansen-Schwartz J, Svensson CL, Xu CB, Edvinsson L: Protein kinase mediated upregulation of endothelin A, endothelin B and 5-hydroxytryptamine 1B/1D receptors during organ culture in rat basilar artery. Br J Pharmacol 2002;137:118-126.
    • (2002) Br J Pharmacol , vol.137 , pp. 118-126
    • Hansen-Schwartz, J.1    Svensson, C.L.2    Xu, C.B.3    Edvinsson, L.4
  • 24
    • 33744459253 scopus 로고    scopus 로고
    • B receptor-mediated vasoconstriction in rat coronary artery after organ culture
    • B receptor-mediated vasoconstriction in rat coronary artery after organ culture. Eur J Pharmacol 2006;539:192-194.
    • (2006) Eur J Pharmacol , vol.539 , pp. 192-194
    • Eskesen, K.1    Edvinsson, L.2
  • 26
    • 33750934386 scopus 로고    scopus 로고
    • Gene expression profiling in the human middle cerebral artery after cerebral ischemia
    • Vikman P, Edvinsson L: Gene expression profiling in the human middle cerebral artery after cerebral ischemia. Eur J Neurol 2006;13:1324-1332.
    • (2006) Eur J Neurol , vol.13 , pp. 1324-1332
    • Vikman, P.1    Edvinsson, L.2
  • 28
    • 4143053531 scopus 로고    scopus 로고
    • Importance of ERK1/2 in upregulation of endothelin type B receptors in cerebral arteries
    • Henriksson M, Xu CB, Edvinsson L: Importance of ERK1/2 in upregulation of endothelin type B receptors in cerebral arteries. Br J Pharmacol 2004;142:1155-1161.
    • (2004) Br J Pharmacol , vol.142 , pp. 1155-1161
    • Henriksson, M.1    Xu, C.B.2    Edvinsson, L.3
  • 29
    • 0025445986 scopus 로고
    • 5-Hydroxytryptamine and thromboxane A2 in ischaemic heart disease
    • De Clerck F, Janssen PA:5-Hydroxytryptamine and thromboxane A2 in ischaemic heart disease. Blood Coagul Fibrinolysis 1990;1:201-209.
    • (1990) Blood Coagul Fibrinolysis , vol.1 , pp. 201-209
    • De Clerck, F.1    Janssen, P.A.2
  • 30
    • 0031900740 scopus 로고    scopus 로고
    • Signal transduction through MAP kinase cascades
    • Lewis TS, Shapiro PS, Ahn NG: Signal transduction through MAP kinase cascades. Adv Cancer Res 1998;74:49-139.
    • (1998) Adv Cancer Res , vol.74 , pp. 49-139
    • Lewis, T.S.1    Shapiro, P.S.2    Ahn, N.G.3
  • 31
    • 7044274054 scopus 로고    scopus 로고
    • Mitogen activated protein kinases as targets for development of novel anti-inflammatory drugs
    • Karin M: Mitogen activated protein kinases as targets for development of novel anti-inflammatory drugs. Ann Rheum Dis 2004;63(suppl 2):ii62-ii64.
    • (2004) Ann Rheum Dis , vol.63 , Issue.SUPPL. 2
    • Karin, M.1
  • 32
    • 16444372032 scopus 로고    scopus 로고
    • Transcription factors and mitogen-activated protein kinases as molecular targets for chemoprevention with anti-inflammatory phytochemicals
    • Surh YJ, Na HK, Lee SS: Transcription factors and mitogen-activated protein kinases as molecular targets for chemoprevention with anti-inflammatory phytochemicals. Biofactors 2004;21:103-108.
    • (2004) Biofactors , vol.21 , pp. 103-108
    • Surh, Y.J.1    Na, H.K.2    Lee, S.S.3
  • 33
    • 85176670726 scopus 로고    scopus 로고
    • Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR: PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 1995;270:27489-27494.
    • Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR: PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 1995;270:27489-27494.
  • 35
    • 0028988138 scopus 로고
    • SB 203580 is a specific inhibitor of a map kinase homologue which is stimulated by cellular stresses and interleukin-1
    • Cuenda A, Rouse J, Doza YN, Meier R, Cohen P, Gallagher TF, Young PR, Lee JC: SB 203580 is a specific inhibitor of a map kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett 1995;364:229-233.
    • (1995) FEBS Lett , vol.364 , pp. 229-233
    • Cuenda, A.1    Rouse, J.2    Doza, Y.N.3    Meier, R.4    Cohen, P.5    Gallagher, T.F.6    Young, P.R.7    Lee, J.C.8
  • 39
    • 0017282190 scopus 로고
    • Some biological effects of prostaglandin endoperoxide analogs
    • Malmsten C: Some biological effects of prostaglandin endoperoxide analogs. Life Sci 1976;18:169-176.
    • (1976) Life Sci , vol.18 , pp. 169-176
    • Malmsten, C.1
  • 40
    • 0024348514 scopus 로고
    • GR32191, a highly potent and specific thromboxane A2 receptor blocking drug on platelets and vascular and airways smooth muscle in vitro
    • Lumley P, White BP, Humphrey PP: GR32191, a highly potent and specific thromboxane A2 receptor blocking drug on platelets and vascular and airways smooth muscle in vitro. Br J Pharmacol 1989;97:783-794.
    • (1989) Br J Pharmacol , vol.97 , pp. 783-794
    • Lumley, P.1    White, B.P.2    Humphrey, P.P.3
  • 41
    • 0032769402 scopus 로고    scopus 로고
    • Inhibition of vasoconstriction by the thromboxane A2 antagonist GR32191B in the human radial artery
    • He GW, Yang CQ: Inhibition of vasoconstriction by the thromboxane A2 antagonist GR32191B in the human radial artery. Br J Clin Pharmacol 1999;48:207-215.
    • (1999) Br J Clin Pharmacol , vol.48 , pp. 207-215
    • He, G.W.1    Yang, C.Q.2
  • 42
    • 0021058380 scopus 로고
    • Operational models of pharmacological agonism
    • Black JW, Leff P: Operational models of pharmacological agonism. Proc R Soc Lond B Biol Sci 1983;220:141-162.
    • (1983) Proc R Soc Lond B Biol Sci , vol.220 , pp. 141-162
    • Black, J.W.1    Leff, P.2
  • 47
    • 0037020476 scopus 로고    scopus 로고
    • B receptor mRNA expression and contraction during organ culture of rat mesenteric artery
    • B receptor mRNA expression and contraction during organ culture of rat mesenteric artery. Eur J Pharmacol 2002;452:215-222.
    • (2002) Eur J Pharmacol , vol.452 , pp. 215-222
    • Uddman, E.1    Adner, M.2    Edvinsson, L.3
  • 48
    • 0037637617 scopus 로고    scopus 로고
    • Intracellular pathways involved in upregulation of vascular endothelin type B receptors in cerebral arteries of the rat
    • Henriksson M, Stenman E, Edvinsson L: Intracellular pathways involved in upregulation of vascular endothelin type B receptors in cerebral arteries of the rat. Stroke 2003;34:1479-1483.
    • (2003) Stroke , vol.34 , pp. 1479-1483
    • Henriksson, M.1    Stenman, E.2    Edvinsson, L.3
  • 49
    • 33645217626 scopus 로고    scopus 로고
    • Involvement of protein kinases on the upregulation of endothelin receptors in rat basilar and mesenteric arteries
    • Jamali R, Edvinsson L: Involvement of protein kinases on the upregulation of endothelin receptors in rat basilar and mesenteric arteries. Exp Biol Med (Maywood) 2006;231:403-411.
    • (2006) Exp Biol Med (Maywood) , vol.231 , pp. 403-411
    • Jamali, R.1    Edvinsson, L.2
  • 50
    • 0942265970 scopus 로고    scopus 로고
    • Vascular oxygen sensing: Detection of novel candidates by proteomics and organ culture
    • discussion 792
    • Thorne GD, Hilliard GM, Paul RJ: Vascular oxygen sensing: detection of novel candidates by proteomics and organ culture. J Appl Physiol 2004;96:802-808; discussion 792.
    • (2004) J Appl Physiol , vol.96 , pp. 802-808
    • Thorne, G.D.1    Hilliard, G.M.2    Paul, R.J.3
  • 52
    • 0019729004 scopus 로고
    • Prostacyclin (PGI2) release accompanying angiotensin conversion in rat mesenteric vasculature
    • Dusting GJ, Mullins EM, Nolan RD: Prostacyclin (PGI2) release accompanying angiotensin conversion in rat mesenteric vasculature. Eur J Pharmacol 1981;70:129-137.
    • (1981) Eur J Pharmacol , vol.70 , pp. 129-137
    • Dusting, G.J.1    Mullins, E.M.2    Nolan, R.D.3
  • 53
    • 0034853246 scopus 로고    scopus 로고
    • Nitric oxide-dependent down-regulation of angiotensin II type 2 receptors during experimental sepsis
    • Bucher M, Hobbhahn J, Kurtz A: Nitric oxide-dependent down-regulation of angiotensin II type 2 receptors during experimental sepsis. Crit Care Med 2001;29:1750-1755.
    • (2001) Crit Care Med , vol.29 , pp. 1750-1755
    • Bucher, M.1    Hobbhahn, J.2    Kurtz, A.3
  • 54
    • 4544288302 scopus 로고    scopus 로고
    • Interleukin-1β attenuates endothelin B receptor-mediated airway contractions in a murine in vitro model of asthma: Roles of endothelin converting enzyme and mitogen-activated protein kinase pathways
    • Zhang Y, Adner M, Cardell LO: Interleukin-1β attenuates endothelin B receptor-mediated airway contractions in a murine in vitro model of asthma: roles of endothelin converting enzyme and mitogen-activated protein kinase pathways. Clin Exp Allergy 2004;34:1480-1487.
    • (2004) Clin Exp Allergy , vol.34 , pp. 1480-1487
    • Zhang, Y.1    Adner, M.2    Cardell, L.O.3
  • 55
    • 0033605423 scopus 로고    scopus 로고
    • Internalization of the TXA2 receptor α and β isoforms: Role of the differentially spliced cooh terminus in agonist-promoted receptor internalization
    • Parent JL, Labrecque P, Orsini MJ, Benovic JL: Internalization of the TXA2 receptor α and β isoforms: role of the differentially spliced cooh terminus in agonist-promoted receptor internalization. J Biol Chem 1999;274:8941-8948.
    • (1999) J Biol Chem , vol.274 , pp. 8941-8948
    • Parent, J.L.1    Labrecque, P.2    Orsini, M.J.3    Benovic, J.L.4
  • 56
    • 20744433821 scopus 로고    scopus 로고
    • Involvement of actin in agonist-induced endocytosis of the G protein-coupled receptor for thromboxane A2: Overcoming of actin disruption by arrestin-3 but not arrestin-2
    • Laroche G, Rochdi MD, Laporte SA, Parent JL: Involvement of actin in agonist-induced endocytosis of the G protein-coupled receptor for thromboxane A2: overcoming of actin disruption by arrestin-3 but not arrestin-2. J Biol Chem 2005;280:23215-23224.
    • (2005) J Biol Chem , vol.280 , pp. 23215-23224
    • Laroche, G.1    Rochdi, M.D.2    Laporte, S.A.3    Parent, J.L.4
  • 57
    • 38349086656 scopus 로고    scopus 로고
    • 2 receptor expression by lipid soluble smoking particles through post-transcriptional mechanisms
    • 2 receptor expression by lipid soluble smoking particles through post-transcriptional mechanisms. Atherosclerosis 2008;196:608-616.
    • (2008) Atherosclerosis , vol.196 , pp. 608-616
    • Zhang, W.1    Zhang, Y.2    Edvinsson, L.3    Xu, C.B.4
  • 58
    • 0023742842 scopus 로고    scopus 로고
    • Oates JA, FitzGerald GA, Branch RA, Jackson EK, Knapp HR, Roberts LJ 2nd: Clinical implications of prostaglandin and thromboxane A2 formation (1). N Engl J Med 1988;319:689-698.
    • Oates JA, FitzGerald GA, Branch RA, Jackson EK, Knapp HR, Roberts LJ 2nd: Clinical implications of prostaglandin and thromboxane A2 formation (1). N Engl J Med 1988;319:689-698.
  • 60
    • 0035178346 scopus 로고    scopus 로고
    • 2 and expression of procoagulant activity by monocytes in response to arachidonic acid in diabetes mellitus
    • 2 and expression of procoagulant activity by monocytes in response to arachidonic acid in diabetes mellitus. Prostaglandins Leukot Essent Fatty Acids 2001;65:133-138.
    • (2001) Prostaglandins Leukot Essent Fatty Acids , vol.65 , pp. 133-138
    • Konieczkowski, M.1    Skrinska, V.A.2


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