Lithium chloride attenuates BMP-2 signaling and inhibits osteogenic differentiation through a novel WNT/GSK3- independent mechanism

Bone

Volumn 48, Issue 2, 2011, Pages 321-331

  Li, Jingjing ^a   Khavandgar, Zohreh ^a   Lin, Sue Hwa ^b   Murshed, Monzur ^a  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

BMP; Differentiation; Lithium; Osteoblasts; SMAD

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; GLYCOGEN SYNTHASE KINASE 3; LITHIUM CHLORIDE; LITHIUM ION; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; WNT PROTEIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; ENZYME ACTIVITY; ENZYME INHIBITION; MESENCHYMAL STEM CELL; MOLECULAR MECHANICS; MOUSE; NONHUMAN; OSTEOBLAST; PLURIPOTENT STEM CELL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ALKALINE PHOSPHATASE; ANIMALS; BETA CATENIN; BLOTTING, WESTERN; BONE MORPHOGENETIC PROTEIN 2; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; GLYCOGEN SYNTHASE KINASE 3; LITHIUM CHLORIDE; MESENCHYMAL STEM CELLS; MICE; OSTEOBLASTS; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 78650989154     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2010.09.033     Document Type: Article

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