Molecular effects of lithium exposure during mouse and chick gastrulation and subsequent valve dysmorphogenesis

Birth Defects Research Part A - Clinical and Molecular Teratology

Volumn 82, Issue 7, 2008, Pages 508-518

  Chen, Jizhen ^a   Han, Mingda ^a   Manisastry, Shyam M ^a   Trotta, Patrizia ^a   Serrano, Maria C ^a   Huhta, James C ^a   Linask, Kersti K ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Ebstein's anomaly; GSK 3; Heart; Lithium; Neural crest; Prechordal plate; Valve; Wnt

Indexed keywords

BETA CATENIN; GLYCOGEN SYNTHASE KINASE 3; LITHIUM; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFATC1; WNT PROTEIN;

ANIMAL TISSUE; ARTICLE; CELL POPULATION; CHICK; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; DOPPLER FLOWMETRY; EMBRYO; EMBRYO PATTERN FORMATION; ENDODERM; ENZYME INACTIVATION; ENZYME INHIBITION; FEMALE; FETUS DEVELOPMENT; GASTRULATION; GENE EXPRESSION; HEART DEVELOPMENT; HEX GENE; MOUSE; NONHUMAN; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SOX4 GENE; TERATOGENICITY; UPREGULATION; VALVULOGENESIS;

ANIMALS; ANTIPSYCHOTIC AGENTS; CHICK EMBRYO; GASTRULATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLYCOGEN SYNTHASE KINASE 3; HEART; HEART DEFECTS, CONGENITAL; HEART VALVES; HUMANS; LITHIUM; MICE; MYOCARDIUM; NEURAL CREST; NFATC TRANSCRIPTION FACTORS; WNT PROTEINS;

EID: 47749131573     PISSN: 15420752     EISSN: 15420760     Source Type: Journal    
DOI: 10.1002/bdra.20448     Document Type: Article

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