Robust Adenoviral and Adeno-Associated Viral Gene Transfer to the In Vivo Murine Heart: Application to Study of Phospholamban Physiology

Circulation

Volumn 108, Issue 22, 2003, Pages 2790-2797

  Champion, Hunter C ^a   Georgakopoulos, Dimitrios ^a   Haldar, Saptarsi ^a   Wang, Lili ^b   Wang, Yibin ^c   Kass, David A ^a  

^a JOHNS HOPKINS HOSPITAL   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Aorta; Cardioplegia; Contractility; Gene therapy; Viruses

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; PARVOVIRUS VECTOR; PHOSPHOLAMBAN; PROTEIN; SERCA2A PROTEIN; UNCLASSIFIED DRUG;

ADENO ASSOCIATED VIRUS; ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA OCCLUSION; ARTICLE; CARDIOPLEGIA; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DESCENDING AORTA; DIASTOLE; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; GENETIC TRANSFECTION; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CONTRACTILITY; INDUCED HYPOTHERMIA; MOLECULAR PHYSIOLOGY; MOUSE; NONHUMAN; PHYSIOLOGY; PRESSURE VOLUME CURVE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN LOCALIZATION; SYSTOLE; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; WHOLE BODY COOLING;

ADENOVIRIDAE; ANIMALS; AORTA; BETA-GALACTOSIDASE; CALCIUM-BINDING PROTEINS; CALCIUM-TRANSPORTING ATPASES; CELL SEPARATION; CORONARY CIRCULATION; DEPENDOVIRUS; GENE TRANSFER TECHNIQUES; HEART; MICE; MICE, KNOCKOUT; MYOCYTES, CARDIAC; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; TIME FACTORS; VENTRICULAR FUNCTION, LEFT;

EID: 0345133487     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000096487.88897.9B     Document Type: Article

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