Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice

EMBO Molecular Medicine

Volumn 3, Issue 1, 2011, Pages 50-66

  Ermakova, Olga ^a,e   Piszczek, Lukasz ^a   Luciani, Luisa ^a   Cavalli, Florence M G ^b   Ferreira, Tiago ^a   Farley, Dominika ^a   Rizzo, Stefania ^a   Paolicelli, Rosa Chiara ^a   Al Banchaabouchi, Mumna ^a   Nerlov, Claus ^a   Moriggl, Richard ^c   Luscombe, Nicholas M ^b,d   Gross, Cornelius ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY EMBL   (Italy)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

^d EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^e Instituto Di Biologia Cellulare CNR   (Italy)

Author keywords

Disease susceptibilty; Gene dosage; Human 17q21.2 region; Phenotypic analysis

Indexed keywords

APOLIPOPROTEIN E; STAT5 PROTEIN;

ANEUPLOIDY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; BEHAVIOR; CHROMOSOME 11; CHROMOSOME DELETION; CHROMOSOME DUPLICATION; CONTROLLED STUDY; DISEASE PREDISPOSITION; GENE DOSAGE; GENE INACTIVATION; GENETIC SUSCEPTIBILITY; GLUCOSE TOLERANCE; HYPERSENSITIVITY; IMMUNOPATHOLOGY; LIPID DIET; METABOLIC SYNDROME X; MOUSE; NEOPLASM; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ANEUPLOIDY; ANIMALS; ANXIETY; ATHEROSCLEROSIS; CHROMOSOMES, MAMMALIAN; DISEASE MODELS, ANIMAL; GENE DOSAGE; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HYPERSENSITIVITY; INTESTINAL NEOPLASMS; METABOLIC SYNDROME X; MICE; MICE, KNOCKOUT; PHENOTYPE; STAT5 TRANSCRIPTION FACTOR;

EID: 78650837175     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201000112     Document Type: Article

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