The transcription factors Stat5a/b are not required for islet development but modulate pancreatic β-cell physiology upon aging

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1773, Issue 9, 2007, Pages 1455-1461

  Lee, Ji Yeon ^a   Gavrilova, Oksana ^a   Davani, Behrous ^a   Na, Risu ^a   Robinson, Gertraud W ^a   Hennighausen, Lothar ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

cells; Glucose homeostasis; Islets of Langerhans; Pdx1 Cre; Rip Cre; Stat5

Indexed keywords

CRE RECOMBINASE; GROWTH HORMONE; INSULIN; PROLACTIN; STAT5A PROTEIN; STAT5B PROTEIN;

AGING; ALLELE; ANIMAL CELL; ARTICLE; CELL FUNCTION; CELL LINE; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; CRE GENE; GENE DELETION; GENE LOCUS; HYPERGLYCEMIA; HYPOTHALAMUS; IMPAIRED GLUCOSE TOLERANCE; LOXP SITE; MOUSE; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PDX1 GENE; PRIORITY JOURNAL; PROTEIN FUNCTION; RIP GENE; SIGNAL TRANSDUCTION; STAT5 GENE; STEM CELL; TRANSCRIPTION REGULATION; TRANSGENE;

AGING; ALLELES; ANIMALS; BLOOD GLUCOSE; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE DELETION; GLUCOSE; GLUCOSE TOLERANCE TEST; IMMUNOHISTOCHEMISTRY; INSULIN-SECRETING CELLS; INTEGRASES; ISLETS OF LANGERHANS; MICE; MICE, TRANSGENIC; MODELS, GENETIC; STAT5 TRANSCRIPTION FACTOR; TRANSGENES;

MUS; MUS MUSCULUS;

EID: 34548488987     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2007.05.010     Document Type: Article

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