Calmodulin kinase II inhibition prevents arrhythmias in RyR2R4496C+/- mice with catecholaminergic polymorphic ventricular tachycardia

Journal of Molecular and Cellular Cardiology

Volumn 50, Issue 1, 2011, Pages 214-222

  Liu, Nian ^a,b   Ruan, Yanfei ^a   Denegri, Marco ^b   Bachetti, Tiziana ^b   Li, Yang ^b   Colombi, Barbara ^b   Napolitano, Carlo ^a,b   Coetzee, William A ^a   Priori, Silvia G ^a,b,c  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b IRCCS   (Italy)

^c UNIVERSITY OF PAVIA   (Italy)

Author keywords

Calcium handling; Catecholamine; Genetics; Therapy; Ventricular tachycardia

Indexed keywords

AUTOCAMTIDE 2 RELATED INHIBITORY PEPTIDE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM ION; ENZYME INHIBITOR; ISOPRENALINE; KN 92; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG;

ADRENERGIC STIMULATION; ADULT ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM TRANSPORT; CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA; CELL ISOLATION; CONTROLLED STUDY; ENZYME INHIBITION; HEART MUSCLE CELL; HEART VENTRICLE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ARRHYTHMIAS, CARDIAC; BENZYLAMINES; BLOTTING, WESTERN; CAFFEINE; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; ELECTROPHYSIOLOGY; EPINEPHRINE; MICE; MYOCYTES, CARDIAC; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SULFONAMIDES; TACHYCARDIA;

MUS;

EID: 78650819612     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2010.10.001     Document Type: Article

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