Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans

Nature Medicine

Volumn 15, Issue 4, 2009, Pages 380-383

  Watanabe, Hiroshi ^a,e   Chopra, Nagesh ^a   Laver, Derek ^b   Hwang, Hyun Seok ^a   Davies, Sean S ^a   Roach, Daniel E ^c   Duff, Henry J ^c   Roden, Dan M ^a   Wilde, Arthur A M ^d   Knollmann, Björn C ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NEWCASTLE   (Australia)

^c UNIVERSITY OF CALGARY   (Canada)

^d UNIVERSITY OF AMSTERDAM   (Netherlands)

^e NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BISOPROLOL; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; FLECAINIDE; METOPROLOL; RYANODINE RECEPTOR 2; VERAPAMIL;

ADULT; ANIMAL MODEL; ARTICLE; CALCIUM TRANSPORT; CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA; CHILD; CLINICAL TRIAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPOLARIZATION; DRUG INHIBITION; FEMALE; HEART RATE; HUMAN; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROBABILITY; PROPHYLAXIS; SARCOPLASMIC RETICULUM;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIAS, CARDIAC; CALCIUM; CHILD; FLECAINIDE; HEART RATE; HUMANS; MALE; MICE; POLYMORPHISM, GENETIC; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SYNDROME; TACHYCARDIA, VENTRICULAR;

MUS;

EID: 64149085800     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.1942     Document Type: Article

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