Targeted inhibition of sarcoplasmic reticulum CaMKII activity results in alterations of Ca2+ homeostasis and cardiac contractility

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 290, Issue 2, 2006, Pages

  Ji, Yong ^a   Zhao, Wen ^a   Li, Bailing ^a   Desantiago, Jaime ^b   Picht, Eckard ^b   Kaetzel, Marcia A ^a   Schultz, Jo El J ^a   Kranias, Evangelia G ^a   Bers, Donald M ^b   Dedman, John R ^a,c  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

^c UNIVERSITY OF CINCINNATI   (United States)

Author keywords

adrenergic stimulation; Calcium calmodulin dependent protein kinase II; Cardiac contractility; Phospholamban; Ryanodine receptor; Transgenic mice

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CAFFEINE; ISOPRENALINE; PHOSPHOLAMBAN; PROTEIN KINASE (CALCIUM,CALMODULIN) II; RYANODINE RECEPTOR; CALCIUM; CALCIUM BINDING PROTEIN; CALMODULIN DEPENDENT PROTEIN KINASE II; CALMODULIN-DEPENDENT PROTEIN KINASE II; CAMKII INHIBITOR AIP; CARDIOTONIC AGENT; PEPTIDE; PROTEIN KINASE (CALCIUM,CALMODULIN);

ANIMAL EXPERIMENT; ARTICLE; BETA ADRENERGIC STIMULATION; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME INHIBITION; HEART CONTRACTION; HEART MUSCLE CONTRACTILITY; MOUSE; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM; TRANSGENIC MOUSE; ANIMAL; DRUG ANTAGONISM; ENZYMOLOGY; FEMALE; HEART MUSCLE; HEART MUSCLE CELL; HOMEOSTASIS; IN VITRO STUDY; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CAFFEINE; CALCIUM; CALCIUM-BINDING PROTEINS; CARDIOTONIC AGENTS; FEMALE; HOMEOSTASIS; ISOPROTERENOL; MICE; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; PEPTIDES; PHOSPHORYLATION; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM;

EID: 33644855766     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00214.2005     Document Type: Article

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