Inhaled anesthetic responses of recombinant receptors and knockin mice harboring α2(S270H/L277A) GABAA receptor subunits that are resistant to isoflurane

Journal of Pharmacology and Experimental Therapeutics

Volumn 336, Issue 1, 2011, Pages 134-144

  Werner, D F ^f   Swihart, A ^a   Rau, V ^c   Jia, F ^d   Borghese, C M ^b   McCracken, M L ^b   Iyer, S ^a   Fanselow, M S ^c   Oh, I ^c   Sonner, J M ^e   Eger II, E I ^c   Harrison, N L ^d   Harris, R A ^b   Homanics, G E ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f BINGHAMTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA2; BENZODIAZEPINE; ETOMIDATE; FLUNITRAZEPAM; HALOTHANE; ISOFLURANE;

AMINO ACID SUBSTITUTION; AMNESIA; ANESTHESIA; ANESTHETIC RECOVERY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; BRAIN ELECTROPHYSIOLOGY; BRAIN SLICE; CONCENTRATION RESPONSE; DENTATE NUCLEUS; DRUG PROTEIN BINDING; FEMALE; GENE MUTATION; GENOTYPE; IMMOBILIZATION; MALE; MINIMUM LUNG ALVEOLUS CONCENTRATION; MOUSE; NERVE CELL; NEWBORN MORTALITY; NONHUMAN; OOCYTE; PRIORITY JOURNAL; REVIEW; RIGHTING REFLEX; XENOPUS LAEVIS;

ANESTHETICS, INHALATION; ANIMALS; CONDITIONING (PSYCHOLOGY); DRUG RESISTANCE; FEAR; FEMALE; GAMMA-AMINOBUTYRIC ACID; GENE KNOCK-IN TECHNIQUES; HUMANS; ISOFLURANE; MICE; MICE, INBRED C57BL; RATS; RECEPTORS, GABA-A; RECOMBINANT PROTEINS; XENOPUS LAEVIS;

EID: 78650764581     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.170431     Document Type: Review

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