-
1
-
-
0142103728
-
Ethanol modulation of excitatory and inhibitory synaptic transmission in rat and monkey dentate granule neurons
-
Ariwodola OJ, Crowder TL, Grant KA, Daunais JB, Friedman DP, and Weiner JL (2003) Ethanol modulation of excitatory and inhibitory synaptic transmission in rat and monkey dentate granule neurons. Alcohol Clin Exp Res 27:1632-1639.
-
(2003)
Alcohol Clin Exp Res
, vol.27
, pp. 1632-1639
-
-
Ariwodola, O.J.1
Crowder, T.L.2
Grant, K.A.3
Daunais, J.B.4
Friedman, D.P.5
Weiner, J.L.6
-
2
-
-
9344236027
-
Ethanol potentiation of GABAergic synaptic transmission may be self-limiting: Role of presynaptic GABA(B) receptors
-
Ariwodola OJ and Weiner JL (2004) Ethanol potentiation of GABAergic synaptic transmission may be self-limiting: role of presynaptic GABA(B) receptors. J Neurosci 24:10679-10686.
-
(2004)
J Neurosci
, vol.24
, pp. 10679-10686
-
-
Ariwodola, O.J.1
Weiner, J.L.2
-
3
-
-
20344392658
-
The benzodiazepine binding site of GABA(A) receptors as a target for the development of novel anxiolytics
-
Atack JR (2005) The benzodiazepine binding site of GABA(A) receptors as a target for the development of novel anxiolytics. Exp Opin Investig Drugs 14:601-618.
-
(2005)
Exp Opin Investig Drugs
, vol.14
, pp. 601-618
-
-
Atack, J.R.1
-
4
-
-
1842533131
-
Acute ethanol administration selectively impairs spatial memory in C57BL/6J mice
-
Berry RB and Matthews DB (2004) Acute ethanol administration selectively impairs spatial memory in C57BL/6J mice. Alcohol 32:9-18.
-
(2004)
Alcohol
, vol.32
, pp. 9-18
-
-
Berry, R.B.1
Matthews, D.B.2
-
5
-
-
0037207457
-
Deletion of the alpha1 or beta2 subunit of GABAA receptors reduces actions of alcohol and other drugs
-
Blednov YA, Jung S, Alva H, Wallace D, Rosahl T, Whiting PJ, and Harris RA (2003a) Deletion of the alpha1 or beta2 subunit of GABAA receptors reduces actions of alcohol and other drugs. J Pharmacol Exp Ther 304:30-36.
-
(2003)
J Pharmacol Exp Ther
, vol.304
, pp. 30-36
-
-
Blednov, Y.A.1
Jung, S.2
Alva, H.3
Wallace, D.4
Rosahl, T.5
Whiting, P.J.6
Harris, R.A.7
-
6
-
-
0037799867
-
GABAA receptor alpha 1 and beta 2 subunit null mutant mice: Behavioral responses to ethanol
-
Blednov YA, Walker D, Alva H, Creech K, Findlay G, and Harris RA (2003b) GABAA receptor alpha 1 and beta 2 subunit null mutant mice: behavioral responses to ethanol. J Pharmacol Exp Ther 305:854-863.
-
(2003)
J Pharmacol Exp Ther
, vol.305
, pp. 854-863
-
-
Blednov, Y.A.1
Walker, D.2
Alva, H.3
Creech, K.4
Findlay, G.5
Harris, R.A.6
-
7
-
-
33644762013
-
The delta subunit of gamma-aminobutyric acid type A receptors does not confer sensitivity to low concentrations of ethanol
-
Borghese CM, Storustovu S, Ebert B, Herd MB, Belelli D, Lambert JJ, Marshall G, Wafford KA, and Harris RA (2006a) The delta subunit of gamma-aminobutyric acid type A receptors does not confer sensitivity to low concentrations of ethanol. J Pharmacol Exp Ther 316:1360-1368.
-
(2006)
J Pharmacol Exp Ther
, vol.316
, pp. 1360-1368
-
-
Borghese, C.M.1
Storustovu, S.2
Ebert, B.3
Herd, M.B.4
Belelli, D.5
Lambert, J.J.6
Marshall, G.7
Wafford, K.A.8
Harris, R.A.9
-
8
-
-
33749009598
-
a receptor alpha1 subunit with near normal affinity for GABA: Characterization in heterologous systems and production of knock-in mice
-
A receptor alpha1 subunit with near normal affinity for GABA: characterization in heterologous systems and production of knock-in mice. J Pharmacol Exp Ther 319:208-218.
-
(2006)
J Pharmacol Exp Ther
, vol.319
, pp. 208-218
-
-
Borghese, C.M.1
Werner, D.F.2
Topf, N.3
Baron, N.V.4
Henderson, L.A.5
Boehm II, S.6
Blednov, Y.A.7
Saad, A.8
Dai, S.9
Pearce, R.A.10
-
9
-
-
16244376193
-
Palatability-dependent appetite and benzodiazepines: New directions from the pharmacology of GABA(A) receptor subtypes
-
Cooper SJ (2005) Palatability-dependent appetite and benzodiazepines: new directions from the pharmacology of GABA(A) receptor subtypes. Appetite 44:133-150.
-
(2005)
Appetite
, vol.44
, pp. 133-150
-
-
Cooper, S.J.1
-
10
-
-
0025895410
-
Acute dependence on depressant drugs is determined by common genes in mice
-
Crabbe JC, Merrill C, and Belknap JK (1991) Acute dependence on depressant drugs is determined by common genes in mice. J Pharmacol Exp Ther 257:663-667.
-
(1991)
J Pharmacol Exp Ther
, vol.257
, pp. 663-667
-
-
Crabbe, J.C.1
Merrill, C.2
Belknap, J.K.3
-
11
-
-
33749024625
-
Alcohol-related genes: Contributions from studies with genetically engineered mice
-
in press
-
Crabbe JC, Phillips TJ, Harris RA, Arends MA, and Koob GF (2006) Alcohol-related genes: contributions from studies with genetically engineered mice. Addict Biol, in press.
-
(2006)
Addict Biol
-
-
Crabbe, J.C.1
Phillips, T.J.2
Harris, R.A.3
Arends, M.A.4
Koob, G.F.5
-
12
-
-
0028987522
-
Effect of zolpidem on gamma-aminobutyric acid (GABA)-induced inhibition predicts the interaction of ethanol with GABA on individual neurons in several rat brain regions
-
Criswell HE, Simson PE, Knapp DJ, Devaud LL, McCown TJ, Duncan GE, Morrow AL, and Breese GR (1995) Effect of zolpidem on gamma-aminobutyric acid (GABA)-induced inhibition predicts the interaction of ethanol with GABA on individual neurons in several rat brain regions. J Pharmacol Exp Ther 273:526-536.
-
(1995)
J Pharmacol Exp Ther
, vol.273
, pp. 526-536
-
-
Criswell, H.E.1
Simson, P.E.2
Knapp, D.J.3
Devaud, L.L.4
McCown, T.J.5
Duncan, G.E.6
Morrow, A.L.7
Breese, G.R.8
-
13
-
-
0041335145
-
Glycine receptor knock-in mice and hyperekplexia-like phenotypes: Comparisons with the null mutant
-
Findlay GS, Phelan R, Roberts MT, Homanics GE, Bergeson SE, Lopreato GF, Mihic SJ, Blednov YA, and Harris RA (2003) Glycine receptor knock-in mice and hyperekplexia-like phenotypes: comparisons with the null mutant. J Neurosci 23:8051-8059.
-
(2003)
J Neurosci
, vol.23
, pp. 8051-8059
-
-
Findlay, G.S.1
Phelan, R.2
Roberts, M.T.3
Homanics, G.E.4
Bergeson, S.E.5
Lopreato, G.F.6
Mihic, S.J.7
Blednov, Y.A.8
Harris, R.A.9
-
14
-
-
23044492151
-
Molecular and systemic mechanisms of general anaesthesia: The "multi-site and multiple mechanisms" concept
-
Grasshoff C, Rudolph U, and Antkowiak B (2005) Molecular and systemic mechanisms of general anaesthesia: the "multi-site and multiple mechanisms" concept. Curr Opin Anaesthesiol 18:386-391.
-
(2005)
Curr Opin Anaesthesiol
, vol.18
, pp. 386-391
-
-
Grasshoff, C.1
Rudolph, U.2
Antkowiak, B.3
-
16
-
-
14544274549
-
Alcohol-induced motor impairment caused by increased extrasynaptic GABA(A) receptor activity
-
Hanchar HJ, Dodson PD, Olsen RW, Otis TS, and Wallner M (2005) Alcohol-induced motor impairment caused by increased extrasynaptic GABA(A) receptor activity. Nat Neurosci 8:339-345.
-
(2005)
Nat Neurosci
, vol.8
, pp. 339-345
-
-
Hanchar, H.J.1
Dodson, P.D.2
Olsen, R.W.3
Otis, T.S.4
Wallner, M.5
-
17
-
-
0032746874
-
Ethanol actions on multiple ion channels: Which are important?
-
Harris RA (1999) Ethanol actions on multiple ion channels: which are important? Alcohol Clin Exp Res 23:1563-1570.
-
(1999)
Alcohol Clin Exp Res
, vol.23
, pp. 1563-1570
-
-
Harris, R.A.1
-
18
-
-
0028999763
-
Mutant mice lacking the gamma isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of gamma-aminobutyrate type A receptors
-
Harris RA, McQuilkin SJ, Paylor R, Abeliovich A, Tonegawa S, and Wehner JM (1995) Mutant mice lacking the gamma isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of gamma-aminobutyrate type A receptors. Proc Natl Acad Sci USA 92:3658-3662.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 3658-3662
-
-
Harris, R.A.1
McQuilkin, S.J.2
Paylor, R.3
Abeliovich, A.4
Tonegawa, S.5
Wehner, J.M.6
-
19
-
-
19944431883
-
A gain-of-function mutation in the GABA receptor produces synaptic and behavioral abnormalities in the mouse
-
Homanics GE, Elsen FP, Ying SW, Jenkins A, Ferguson C, Sloat B, Yuditskaya S, Goldstein PA, Kralic JE, Morrow AL, et al. (2005) A gain-of-function mutation in the GABA receptor produces synaptic and behavioral abnormalities in the mouse. Genes Brain Behav 4:10-19.
-
(2005)
Genes Brain Behav
, vol.4
, pp. 10-19
-
-
Homanics, G.E.1
Elsen, F.P.2
Ying, S.W.3
Jenkins, A.4
Ferguson, C.5
Sloat, B.6
Yuditskaya, S.7
Goldstein, P.A.8
Kralic, J.E.9
Morrow, A.L.10
-
20
-
-
0037315741
-
General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor beta3 subunit
-
Jurd R, Arras M, Lambert S, Drexler B, Siegwart R, Crestani F, Zaugg M, Vogt KE, Ledermann B, Antkowiak B, et al. (2003) General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor beta3 subunit. FASEB J 17:250-252.
-
(2003)
FASEB J
, vol.17
, pp. 250-252
-
-
Jurd, R.1
Arras, M.2
Lambert, S.3
Drexler, B.4
Siegwart, R.5
Crestani, F.6
Zaugg, M.7
Vogt, K.E.8
Ledermann, B.9
Antkowiak, B.10
-
21
-
-
20044369882
-
Genetic essential tremor in gamma-aminobutyric acid A receptor alpha1 subunit knockout mice
-
Kralic JE, Criswell HE, Osterman JL, O'Buckley TK, Wilkie ME, Matthews DB, Hamre K, Breese GR, Homanics GE, and Morrow AL (2005) Genetic essential tremor in gamma-aminobutyric acid A receptor alpha1 subunit knockout mice. J Clin Investig 115:774-779.
-
(2005)
J Clin Investig
, vol.115
, pp. 774-779
-
-
Kralic, J.E.1
Criswell, H.E.2
Osterman, J.L.3
O'Buckley, T.K.4
Wilkie, M.E.5
Matthews, D.B.6
Hamre, K.7
Breese, G.R.8
Homanics, G.E.9
Morrow, A.L.10
-
22
-
-
33644858656
-
Compensatory alteration of inhibitory synaptic circuits in cerebellum and thalamus of gamma-aminobutyric acid type A receptor alpha1 subunit knockout mice
-
Kralic JE, Sidler C, Parpan F, Homanics GE, Morrow AL, and Fritschy JM (2006) Compensatory alteration of inhibitory synaptic circuits in cerebellum and thalamus of gamma-aminobutyric acid type A receptor alpha1 subunit knockout mice. J Comp Neurol 495:408-421.
-
(2006)
J Comp Neurol
, vol.495
, pp. 408-421
-
-
Kralic, J.E.1
Sidler, C.2
Parpan, F.3
Homanics, G.E.4
Morrow, A.L.5
Fritschy, J.M.6
-
23
-
-
0038623051
-
Deletion of GABAA receptor alpha 1 subunit-containing receptors alters responses to ethanol and other anesthetics
-
Kralic JE, Wheeler M, Renzi K, Ferguson C, O'Buckley TK, Grobin AC, Morrow AL, and Homanics GE (2003) Deletion of GABAA receptor alpha 1 subunit-containing receptors alters responses to ethanol and other anesthetics. J Pharmacol Exp Ther 305:600-607.
-
(2003)
J Pharmacol Exp Ther
, vol.305
, pp. 600-607
-
-
Kralic, J.E.1
Wheeler, M.2
Renzi, K.3
Ferguson, C.4
O'Buckley, T.K.5
Grobin, A.C.6
Morrow, A.L.7
Homanics, G.E.8
-
24
-
-
0029760082
-
Quantitative trait loci for ethanol sensitivity in the LS x SS recombinant inbred strains: Interval mapping
-
Markel PD, Fulker DW, Bennett B, Corley RP, DeFries JC, Erwin VG, and Johnson TE (1996) Quantitative trait loci for ethanol sensitivity in the LS x SS recombinant inbred strains: interval mapping. Behav Genet 26:447-458.
-
(1996)
Behav Genet
, vol.26
, pp. 447-458
-
-
Markel, P.D.1
Fulker, D.W.2
Bennett, B.3
Corley, R.P.4
Defries, J.C.5
Erwin, V.G.6
Johnson, T.E.7
-
25
-
-
0034108997
-
Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype
-
McKernan RM, Rosahl TW, Reynolds DS, Sur C, Wafford KA, Atack JR, Farrar S, Myers J, Cook G, Ferris P, et al. (2000) Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype. Nat Neurosci 3:587-592.
-
(2000)
Nat Neurosci
, vol.3
, pp. 587-592
-
-
McKernan, R.M.1
Rosahl, T.W.2
Reynolds, D.S.3
Sur, C.4
Wafford, K.A.5
Atack, J.R.6
Farrar, S.7
Myers, J.8
Cook, G.9
Ferris, P.10
-
26
-
-
0029670123
-
Which GABAA-receptor subtypes really occur in the brain?
-
McKernan RM and Whiting PJ (1996) Which GABAA-receptor subtypes really occur in the brain? Trends Neurosci 19:139-143.
-
(1996)
Trends Neurosci
, vol.19
, pp. 139-143
-
-
McKernan, R.M.1
Whiting, P.J.2
-
27
-
-
0035678460
-
GABA(A)-receptor delta subunit knockout mice have multiple defects in behavioral responses to ethanol
-
Mihalek RM, Bowers BJ, Wehner JM, Kralic JE, VanDoren MJ, Morrow AL, and Homanics GE (2001) GABA(A)-receptor delta subunit knockout mice have multiple defects in behavioral responses to ethanol. Alcohol Clin Exp Res 25:1708-1718.
-
(2001)
Alcohol Clin Exp Res
, vol.25
, pp. 1708-1718
-
-
Mihalek, R.M.1
Bowers, B.J.2
Wehner, J.M.3
Kralic, J.E.4
VanDoren, M.J.5
Morrow, A.L.6
Homanics, G.E.7
-
28
-
-
0005535917
-
Spatial localization does not require the presence of local cues
-
Morris RGM (1981) Spatial localization does not require the presence of local cues. Learn Motiv 12:239-260.
-
(1981)
Learn Motiv
, vol.12
, pp. 239-260
-
-
Morris, R.G.M.1
-
29
-
-
0036118231
-
Volatile anesthetic actions on the GABAA receptors: Contrasting effects of alpha 1(S270) and beta 2(N265) point mutations
-
Nishikawa K, Jenkins A, Paraskevakis I, and Harrison NL (2002) Volatile anesthetic actions on the GABAA receptors: contrasting effects of alpha 1(S270) and beta 2(N265) point mutations. Neuropharmacology 42:337-345.
-
(2002)
Neuropharmacology
, vol.42
, pp. 337-345
-
-
Nishikawa, K.1
Jenkins, A.2
Paraskevakis, I.3
Harrison, N.L.4
-
30
-
-
0029909204
-
Differential synaptic localization of two major gamma-aminobutyric acid type A receptor alpha subunits on hippocampal pyramidal cells
-
Nusser Z, Sieghart W, Benke D, Fritschy JM, and Somogyi P (1996) Differential synaptic localization of two major gamma-aminobutyric acid type A receptor alpha subunits on hippocampal pyramidal cells. Proc Natl Acad Sci USA 93:11939-11944.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11939-11944
-
-
Nusser, Z.1
Sieghart, W.2
Benke, D.3
Fritschy, J.M.4
Somogyi, P.5
-
31
-
-
33744968446
-
a receptors
-
A receptors. J Neurosci 26:5673-5683.
-
(2006)
J Neurosci
, vol.26
, pp. 5673-5683
-
-
Ponomarev, I.1
Maiya, R.2
Harnett, M.T.3
Schafer, G.L.4
Ryabinin, A.E.5
Blednov, Y.A.6
Morikawa, H.7
Boehm II, S.L.8
Homanics, G.E.9
Berman, A.10
-
32
-
-
0033592682
-
Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes
-
Rudolph U, Crestani F, Benke D, Brunig I, Benson JA, Fritschy JM, Martin JR, Bluethmann H, and Mohler H (1999) Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes. Nature (Lond) 401:796-800.
-
(1999)
Nature (Lond)
, vol.401
, pp. 796-800
-
-
Rudolph, U.1
Crestani, F.2
Benke, D.3
Brunig, I.4
Benson, J.A.5
Fritschy, J.M.6
Martin, J.R.7
Bluethmann, H.8
Mohler, H.9
-
33
-
-
0036673411
-
Subunit composition, distribution and function of GABA(A) receptor subtypes
-
Sieghart W and Sperk G (2002) Subunit composition, distribution and function of GABA(A) receptor subtypes. Curr Top Med Chem 2:795-816.
-
(2002)
Curr Top Med Chem
, vol.2
, pp. 795-816
-
-
Sieghart, W.1
Sperk, G.2
-
34
-
-
20444382383
-
The tipsy terminal: Presynaptic effects of ethanol
-
Siggins GR, Roberto M, and Nie Z (2005) The tipsy terminal: presynaptic effects of ethanol. Pharmacol Ther 107:80-98.
-
(2005)
Pharmacol Ther
, vol.107
, pp. 80-98
-
-
Siggins, G.R.1
Roberto, M.2
Nie, Z.3
-
35
-
-
0036326314
-
Hormonally regulated alpha(4)beta(2)delta GABA(A) receptors are a target for alcohol
-
Sundstrom-Poromaa I, Smith DH, Gong QH, Sabado TN, Li X, Light A, Wiedmann M, Williams K, and Smith SS (2002) Hormonally regulated alpha(4)beta(2)delta GABA(A) receptors are a target for alcohol. Nat Neurosci 5:721-722.
-
(2002)
Nat Neurosci
, vol.5
, pp. 721-722
-
-
Sundstrom-Poromaa, I.1
Smith, D.H.2
Gong, Q.H.3
Sabado, T.N.4
Li, X.5
Light, A.6
Wiedmann, M.7
Williams, K.8
Smith, S.S.9
-
36
-
-
0030900731
-
Stoichiometry and assembly of a recombinant GABAA receptor subtype
-
Tretter V, Ehya N, Fuchs K, and Sieghart W (1997) Stoichiometry and assembly of a recombinant GABAA receptor subtype. J Neurosci 17:2728-2737.
-
(1997)
J Neurosci
, vol.17
, pp. 2728-2737
-
-
Tretter, V.1
Ehya, N.2
Fuchs, K.3
Sieghart, W.4
-
37
-
-
0033778416
-
Tryptophan scanning mutagenesis in TM2 of the GABA(A) receptor alpha subunit: Effects on channel gating and regulation by ethanol
-
Ueno S, Lin A, Nikolaeva N, Trudell JR, Mihic SJ, Harris RA, and Harrison NL (2000) Tryptophan scanning mutagenesis in TM2 of the GABA(A) receptor alpha subunit: effects on channel gating and regulation by ethanol. Br J Pharmacol 131:296-302.
-
(2000)
Br J Pharmacol
, vol.131
, pp. 296-302
-
-
Ueno, S.1
Lin, A.2
Nikolaeva, N.3
Trudell, J.R.4
Mihic, S.J.5
Harris, R.A.6
Harrison, N.L.7
-
38
-
-
0345598083
-
Ethanol enhances alpha 4 beta 3 delta and alpha 6 beta 3 delta gamma-aminobutyric acid type A receptors at low concentrations known to affect humans
-
Wallner M, Hanchar HJ, and Olsen RW (2003) Ethanol enhances alpha 4 beta 3 delta and alpha 6 beta 3 delta gamma-aminobutyric acid type A receptors at low concentrations known to affect humans. Proc Natl Acad Sci USA 100:15218-15223.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15218-15223
-
-
Wallner, M.1
Hanchar, H.J.2
Olsen, R.W.3
-
39
-
-
0030975522
-
Differential ethanol sensitivity of subpopulations of GABAA synapses onto rat hippocampal CA1 pyramidal neurons
-
Weiner JL, Gu C, and Dunwiddie TV (1997) Differential ethanol sensitivity of subpopulations of GABAA synapses onto rat hippocampal CA1 pyramidal neurons. J Neurophysiol 77:1306-1312.
-
(1997)
J Neurophysiol
, vol.77
, pp. 1306-1312
-
-
Weiner, J.L.1
Gu, C.2
Dunwiddie, T.V.3
-
40
-
-
33746734941
-
Ethanol modulation of GABAergic transmission: The view from the slice
-
Weiner JL and Valenzuela CF (2006) Ethanol modulation of GABAergic transmission: the view from the slice. Pharmacol Ther 111:533-554.
-
(2006)
Pharmacol Ther
, vol.111
, pp. 533-554
-
-
Weiner, J.L.1
Valenzuela, C.F.2
|