The role of the IL-12 cytokine family in directing T-cell responses in oral candidosis

Clinical and Developmental Immunology

Volumn 2011, Issue , 2011, Pages

  Wei, Xiao Qing ^a   Rogers, Helen ^a   Lewis, Michael A O ^a   Williams, David W ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 12; INTERLEUKIN 23; INTERLEUKIN 27; INTERLEUKIN 35; PATTERN RECOGNITION RECEPTOR;

ANTIGEN RECOGNITION; CANDIDA ALBICANS; CELLULAR IMMUNITY; CYTOKINE PRODUCTION; DENDRITIC CELL; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; REVIEW; T LYMPHOCYTE; TH1 CELL; TH17 CELL; TH2 CELL; THRUSH; ANIMAL; GENETICS; HOST PATHOGEN INTERACTION; HUMAN; IMMUNOLOGY; IMMUNOMODULATION; MOUSE; MULTIGENE FAMILY; TH1 TH2 BALANCE;

ANIMALS; CANDIDIASIS, ORAL; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, CELLULAR; IMMUNOMODULATION; INTERLEUKIN-12; MICE; MULTIGENE FAMILY; RECEPTORS, PATTERN RECOGNITION; T-LYMPHOCYTES; TH1-TH2 BALANCE;

EID: 78650751852     PISSN: 17402522     EISSN: 17402530     Source Type: Journal    
DOI: 10.1155/2011/697340     Document Type: Review

References (90)

1. Schulze J., Sonnenborn U., Yeasts in the gut: from commensals to infectious agents Deutsches Arzteblatt 2009 106 51-52 837 842
2. Meiller T. F., Hube B., Schild L., Shirtliff M. E., Scheper M. A., Winkler R., Ton A., Jabra-Rizk M. A., A novel immune evasion strategy of Candida albicans: proteolytic cleavage of a salivary antimicrobial peptide PLoS ONE 2009 4 4
3. Thaweboon S., Thaweboon B., Srithavaj T., Choonharuangdej S., Oral colonization of Candida species in patients receiving radiotherapy in the head and neck area Quintessence International 2008 39 2 e52 e57
4. Vultaggio A., Lombardelli L., Giudizi M. G., Biagiotti R., Mazzinghi B., Scaletti C., Mazzetti M., Livi C., Leoncini F., Romagnani S., Maggi E., Piccinni M.-P., T cells specific for Candida albicans antigens and producing type 2 cytokines in lesional mucosa of untreated HIV-infected patients with pseudomembranous oropharyngeal candidiasis Microbes and Infection 2008 10 2 166 174
5. de Repentigny L., Lewandowski D., Aumont F., Hanna Z., Jolicoeur P., Oral mucosal cell response to Candida albicans in transgenic mice expressing HIV-1 Methods in Molecular Biology 2009 470 359 368
6. Thomas M. S., Parolia A., Kundabala M., Vikram M., Asthma and oral health: a review Australian Dental Journal 2010 55 2 128 133
7. Akpan A., Morgan R., Oral candidiasis Postgraduate Medical Journal 2002 78 922 455 459
8. Williams D. W., Bartie K. L., Potts A. J., Wilson M. J., Fardy M. J., Lewis M. A., Strain persistence of invasive Candida albicans in chronic hyperplastic candidosis that underwent malignant change Gerodontology 2001 18 2 73 78
9. Sharon V., Fazel N., Oral candidiasis and angular cheilitis Dermatologic Therapy 2010 23 3 230 242
10. Kirkpatrick C. H., Hill H. R., Chronic mucocutaneous candidiasis Pediatric Infectious Disease Journal 2001 20 2 197 206
11. Lin L., Ibrahim A. S., Xu X., Farber J. M., Avanesian V., Baquir B., Fu Y., French S. W., Edwards Jr. J. E., Spellberg B., Th1-Th17 cells mediate protective adaptive immunity against Staphylococcus aureus and Candida albicans infection in mice PLoS Pathogens 2009 5 12
12. Wu Y., Tan Z., Liu Z., Xia D., Li J., Local IL-23 expression in murine vaginal candidiasis and its relationship with infection and immune status Journal of Huazhong University of Science and Technology. Medical Sciences 2006 26 2 245 247
13. Bonifazi P., Zelante T., D'Angelo C., De Luca A., Moretti S., Bozza S., Perruccio K., Iannitti R. G., Giovannini G., Volpi C., Fallarino F., Puccetti P., Romani L., Balancing inflammation and tolerance in vivo through dendritic cells by the commensal Candida albicans Mucosal Immunology 2009 2 4 362 374
14. Jouault T., Sarazin A., Martinez-esparza M., Fradin C., Sendid B., Poulain D., Host responses to a versatile commensal: PAMPs and PRRs interplay leading to tolerance or infection by Candida albicans Cellular Microbiology 2009 11 7 1007 1015
15. Gil M. L., Gozalbo D., Role of Toll-like receptors in systemic Candida albicans infections Frontiers in Bioscience 2009 14 570 582
16. Antonopoulos C., Cumberbatch M., Mee J. B., Dearman R. J., Wei X.-Q., Liew F. Y., Kimber I., Groves R. W., IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis Journal of Leukocyte Biology 2008 83 2 361 367
17. Verdijk P., Aarntzen E. H. J. G., Lesterhuis W. J., Boullart A. C. I., Kok E., Van Rossum M. M., Strijk S., Eijckeler F., Bonenkamp J. J., Jacobs J. F. M., Blokx W., Vankrieken H. J. M., Joosten I., Boerman O. C., Oyen W. J. G., Adema G., Punt C. J. A., Figdor C. G., De Vries I. J. M., Limited amounts of dendritic cells migrate into thet-cell area of lymph nodes but have high immune activating potential in melanoma patients Clinical Cancer Research 2009 15 7 2531 2540
18. Del Prete A., Vermi W., Dander E., Otero K., Barberis L., Luini W., Bernasconi S., Sironi M., Santoro A., Garlanda C., Faccheti F., Wymann M. P., Vecchi A., Hirsch E., Mantovani A., Sozzani S., Defective dendritic cell migration and activation of adaptive immunity in PI3K -deficient mice EMBO Journal 2004 23 17 3505 3515
19. Ryan K. R., Hong M., Arkwright P. D., Gennery A. R., Costigan C., Dominguez M., Denning D., McConnell V., Cant A. J., Abinun M., Spickett G. P., Lilic D., Impaired dendritic cell maturation and cytokine production in patients with chronic mucocutanous candidiasis with or without APECED Clinical and Experimental Immunology 2008 154 3 406 414
20. Goriely S., Goldman M., Interleukin-12 family members and the balance between rejection and tolerance Current Opinion in Organ Transplantation 2008 13 1 4 9
21. Hasan A. A., Ghaemmaghami A. M., Fairclough L., Robins A., Sewell H. F., Shakib F., Allergen-driven suppression of thiol production by human dendritic cells and the effect of thiols on T cell function Immunobiology 2009 214 1 2 16
22. Oldenhove G., Bouladoux N., Wohlfert E. A., Hall J. A., Chou D., Dos santos L., O'Brien S., Blank R., Lamb E., Natarajan S., Kastenmayer R., Hunter C., Grigg M. E., Belkaid Y., Decrease of Foxp3+ Treg Cell Number and Acquisition of Effector Cell Phenotype during Lethal Infection Immunity 2009 31 5 772 786
23. McLachlan J. B., Catron D. M., Moon J. J., Jenkins M. K., Dendritic Cell Antigen Presentation Drives Simultaneous Cytokine Production by Effector and Regulatory T Cells in Inflamed Skin Immunity 2009 30 2 277 288
24. Loser K., Beissert S., Dendritic Cells and T Cells in the Regulation of Cutaneous Immunity Advances in Dermatology 2007 23 307 333
25. Goddard S., Youster J., Morgan E., Adams D. H., Interleukin-10 Secretion Differentiates Dendritic Cells from Human Liver and Skin American Journal of Pathology 2004 164 2 511 519
26. Gee K., Guzzo C., Mat N. F. C., Ma W., Kumar A., The IL-12 family of cytokines in infection, inflammation and autoimmune disorders Inflammation and AllergyDrug Targets 2009 8 1 40 52
27. Siegemund S., Schtze N., Freudenberg M. A., Lutz M. B., Straubinger R. K., Alber G., Production of IL-12, IL-23 and IL-27p28 by bone marrow-derived conventional dendritic cells rather than macrophages after LPS/TLR4-dependent induction by Salmonella Enteritidis Immunobiology 2008 212 9-10 739 750
28. Sutmuller R. P. M., Den Brok M. H. M. G. M., Kramer M., Bennink E. J., Toonen L. W. J., Kullberg B.-J., Joosten L. A., Akira S., Netea M. G., Adema G. J., Toll-like receptor 2 controls expansion and function of regulatory T cells Journal of Clinical Investigation 2006 116 2 485 494
29. Netea M. G., Sutmuller R., Hermann C., Van Der Graaf C. A. A., Van Der Meer J. W. M., Van Krieken J. H., Hartung T., Adema G., Kullberg B. J., Toll-Like Receptor 2 Suppresses Immunity against Candida albicans through Induction of IL-10 and Regulatory T Cells The Journal of Immunology 2004 172 6 3712 3718
30. Miyazato A., Nakamura K., Yamamoto N., Mora-Montes H. M., Tanaka M., Abe Y., Tanno D., Inden K., Gang X., Ishii K., Takeda K., Akira S., Saijo S., Iwakura Y., Adachi Y., Ohno N., Mitsutake K., Gow N. A. R., Kaku M., Kawakami K., Toll-like receptor 9-dependent activation of myeloid dendritic cells by deoxynucleic acids from Candida albicans Infection and Immunity 2009 77 7 3056 3064
31. Brown G. D., Gordon S., Immune recognition. A new receptor for beta-glucans Nature 2001 413 36 37
32. Goodridge H. S., Underhill D. M., Fungal Recognition by TLR2 and Dectin-1 Handbook of Experimental Pharmacology 2008 183 87 109
33. Taylor B. N., Saavedra M., Fidel P. L. Jr., Local Th1/Th2 cytokine production during experimental vaginal candidiasis: potential importance of transforming growth factor- Medical Mycology 2000 38 6 419 431
34. LeibundGut-Landmann S., Gro O., Robinson M. J., Osorio F., Slack E. C., Tsoni S. V., Schweighoffer E., Tybulewicz V., Brown G. D., Ruland J., Reis e Sousa C., Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17 Nature Immunology 2007 8 6 630 638
35. Glocker E.-O., Hennigs A., Nabavi M., Schffer A. A., Woellner C., Salzer U., Pfeifer D., Veelken H., Warnatz K., Tahami F., Jamal S., Manguiat A., Rezaei N., Amirzargar A. A., Plebani A., Hannesschlger N., Gross O., Ruland J., Grimbacher B., A homozygous CARD9 mutation in a family with susceptibility to fungal infections The New England Journal of Medicine 2009 361 18 1727 1735
36. Ferwerda G., Meyer-Wentrup F., Kullberg B.-J., Netea M. G., Adema G. J., Dectin-1 synergizes with TLR2 and TLR4 for cytokine production in human primary monocytes and macrophages Cellular Microbiology 2008 10 10 2058 2066
37. Ferwerda B., Ferwerda G., Plantinga T. S., Willment J. A., Van Spriel A. B., Venselaar H., Elbers C. C., Johnson M. D., Cambi A., Huysamen C., Jacobs L., Jansen T., Verheijen K., Masthoff L., Morr S. A., Vriend G., Williams D. L., Perfect J. R., Joosten L. A. B., Wijmenga C., Van Der Meer J. W. M., Adema G. J., Kullberg B. J., Brown G. D., Netea M. G., Human dectin-1 deficiency and mucocutaneous fungal infections The New England Journal of Medicine 2009 361 18 1760 1767
38. Murphy E. E., Terres G., Macatonia S. E., Hsieh C.-S., Mattson J., Lanier L., Wysocka M., Trinchieri G., Murphy K., O'Garra A., B7 and interleukin 12 cooperate for proliferation and interferon production by mouse T helper clones that are unresponsive to B7 costimulation Journal of Experimental Medicine 1994 180 1 223 231
39. Macatonia S. E., Hsieh C.-S., Murphy K. M., O'Garra A., Dendritic cells and macrophages are required for Th1 development of CD8+ t cells from TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN- production is IFN- -dependent International Immunology 1993 5 9 1119 1128
40. Oppmann B., Lesley R., Blom B., Timans J. C., Xu Y., Hunte B., Vega F., Yu N., Wang J., Singh K., Zonin F., Vaisberg E., Churakova T., Liu M.-R., Gorman D., Wagner J., Zurawski S., Liu Y.-J., Abrams J. S., Moore K. W., Rennick D., De Waal-Malefyt R., Hannum C., Bazan J. F., Kastelein R. A., Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12 Immunity 2000 13 5 715 725
41. Zelante T., De Luca A., Bonifazi P., Montagnoli C., Bozza S., Moretti S., Belladonna M. L., Vacca C., Conte C., Mosci P., Bistoni F., Puccetti P., Kastelein R. A., Kopf M., Romani L., IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance The European Journal of Immunology 2007 37 10 2695 2706
42. Chen L., Wei X.-Q., Evans B., Jiang W., Aeschlimann D., IL-23 promotes osteoclast formation by up-regulation of receptor activator of NF-B (RANK) expression in myeloid precursor cells The European Journal of Immunology 2008 38 10 2845 2854
43. Devergne O., Hummel M., Koeppen H., Le Beau M. M., Nathanson E. C., Kieff E., Birkenbach M., A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes Journal of Virology 1996 70 2 1143 1153
44. Pflanz S., Timans J. C., Cheung J., Rosales R., Kanzler H., Gilbert J., Hibbert L., Churakova T., Travis M., Vaisberg E., Blumenschein W. M., Mattson J. D., Wagner J. L., To W., Zurawski S., McClanahan T. K., Gorman D. M., Bazan J. F., De Waal Malefyt R., Rennick D., Kastelein R. A., IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD8+ T cells Immunity 2002 16 6 779 790
45. Murugaiyan G., Mittal A., Lopez-Diego R., Maier L. M., Anderson D. E., Weiner H. L., IL-27 is a key regulator of IL-10 and IL-17 production by human CD8+ T cells The Journal of Immunology 2009 183 4 2435 2443
46. Niedbala W., Wei X.-Q., Cai B., Hueber A. J., Leung B. P., McInnes I. B., Liew F. Y., IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells European The Journal of Immunology 2007 37 11 3021 3029
47. Furuzawa-Carballeda J., Vargas-Rojas M. I., Cabral A. R., Autoimmune inflammation from the Th17 perspective Autoimmunity Reviews 2007 6 3 169 175
48. Devergne O., Birkenbach M., Kieff E., Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin Proceedings of the National Academy of Sciences of the United States of America 1997 94 22 12041 12046
49. Collison L. W., Workman C. J., Kuo T. T., Boyd K., Wang Y., Vignali K. M., Cross R., Sehy D., Blumberg R. S., Vignali D. A. A., The inhibitory cytokine IL-35 contributes to regulatory T-cell function Nature 2007 450 7169 566 569
50. Pedraza-Sanchez S., Herrera-Barrios M. T., Aldana-Vergara R., Neumann-Ordonez M., Gonzalez-Hernandez Y., Sada-Diaz E., de Beaucoudrey L., Casanova J. L., Torres-Rojas M., Bacille Calmette-Guerin infection and disease with fatal outcome associated with a point mutation in the interleukin-12/ interleukin-23 receptor beta-1 chain in two Mexican families International Journal of Infectious Diseases 2010 14S3 e256 e260
51. Kim H. S., Choi E. H., Khan J., Roilides E., Francesconi A., Kasai M., Sein T., Schaufele R. L., Sakurai K., Son C. G., Greer B. T., Chanock S., Lyman C. A., Walsh T. J., Expression of genes encoding innate host defense molecules in normal human monocytes in response to Candida albicans Infection and Immunity 2005 73 6 3714 3724
52. Pepe M., Jirillo E., Covelli V., In vitro infection of human monocyte-derived dendritic cells with Candida albicans: receptorial involvement and therapeutic implications Current Pharmaceutical Design 2006 12 32 4263 4269
53. Pietrella D., Lupo P., Bistoni F., Vecchiarelli A., An early imbalance of interleukin 12 influences the adjuvant effect of mannoproteins of cryptococcus neoformans Cellular Microbiology 2004 6 9 883 891
54. Montagnoli C., Sandini S., Bacci A., Romani L., La Valle R., Immunogenicity and protective effect of recombinant enolase of Candida albicans in a murine model of systemic candidiasis Medical Mycology 2004 42 4 319 324
55. Ishibashi H., Uchida K., Nishiyama Y., Yamaguchi H., Abe S., Oral administration of itraconazole solution has superior efficacy in experimental oral and oesophageal candidiasis in mice than its intragastric administration Journal of Antimicrobial Chemotherapy 2007 59 2 317 320
56. Clemons K. V., Gonzalez G. M., Singh G., Imai J., Espiritu M., Parmar R., Stevens D. A., Development of an orogastrointestinal mucosal model of candidiasis with dissemination to visceral organs Antimicrobial Agents and Chemotherapy 2006 50 8 2650 2657
57. Van Spriel A. B., Van den Herik-Oudijk I. E., Van de Winkel J. G. J., Neutrophil Fc RI as target for immunotherapy of invasive candidiasis The Journal of Immunology 2001 166 12 7019 7022
58. Farah C. S., Hu Y., Riminton S., Ashman R. B., Distinct roles for interleukin-12p40 and tumour necrosis factor in resistance to oral candidiasis defined by gene-targeting Oral Microbiology and Immunology 2006 21 4 252 255
59. Lev-Sagie A., Nyirjesy P., Tarangelo N., Bongiovanni A. M., Bayer C., Linhares I. M., Giraldo P. C., Ledger W. J., Witkin S. S., Hyaluronan in vaginal secretions: association with recurrent vulvovaginal candidiasis American Journal of Obstetrics and Gynecology 2009 201 2 206 e1
60. Layh-Schmitt G., Colbert R. A., The interleukin-23/interleukin-17 axis in spondyloarthritis Current Opinion in Rheumatology 2008 20 4 392 397
61. Annunziato F., Cosmi L., Liotta F., Maggi E., Romagnani S., The phenotype of human Th17 cells and their precursors, the cytokines that mediate their differentiation and the role of Th17 cells in inflammation International Immunology 2008 20 11 1361 1368
62. Perona-Wright G., Jenkins S. J., O'Connor R. A., Zienkiewicz D., McSorley H. J., Maizels R. M., Anderton S. M., MacDonald A. S., A pivotal role for CD40-mediated IL-6 production by dendritic cells during IL-17 induction in vivo The Journal of Immunology 2009 182 5 2808 2815
63. Conti H. R., Shen F., Nayyar N., Stocum E., Sun J. N., Lindemann M. J., Ho A. W., Hai J. H., Yu J. J., Jung J. W., Filler S. G., Masso-Welch P., Edgerton M., Gaffen S. L., Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis Journal of Experimental Medicine 2009 206 2 299 311
64. Feng X. M., Liu N., Yang S. G., Hu L. Y., Chen X. L., Fang Z. H., Ren Q., Lu S. H., Liu B., Han Z. C., Regulation of the class II and class I MHC pathways in human THP-1 monocytic cells by interleukin-27 Biochemical and Biophysical Research Communications 2008 367 3 553 559
65. Sheng K.-C., Pouniotis D. S., Wright M. D., Tang C. K., Lazoura E., Pietersz G. A., Apostolopoulos V., Mannan derivatives induce phenotypic and functional maturation of mouse dendritic cells Immunology 2006 118 3 372 383
66. Roudbary M., Roudbar Mohammadi S., Bozorgmehr M., Moazzeni S. M., The effects of Candida albicans cell wall protein fraction on dendritic cell maturation Iranian The Journal of Immunology 2009 6 2 67 74
67. Skrzypek F., Cenci E., Pietrella D., Rachini A., Bistoni F., Vecchiarelli A., Dectin-1 is required for human dendritic cells to initiate immune response to Candida albicans through Syk activation Microbes and Infection 2009 11 6-7 661 670
68. Baumgartner C. K., Malherbe L. P., Regulation of CD4 T-cell receptor diversity by vaccine adjuvants Immunology 2010 130 1 16 22
69. De Bernardis F., Santoni G., Boccanera M., Spreghini E., Adriani D., Morelli L., Cassone A., Local anticandidal immune responses in a rat model of vaginal infection by and protection against Candida albicans Infection and Immunity 2000 68 6 3297 3304
70. Myers T. A., Leigh J. E., Arribas A. R., Hager S., Clark R., Lilly E., Fidel P. L. Jr., Immunohistochemical evaluation of T cells in oral lesions from human immunodeficiency virus-positive persons with oropharyngeal candidiasis Infection and Immunity 2003 71 2 956 963
71. Leigh J. E., Steele C., Wormley F., Fidel P. L. Jr., Salivary cytokine profiles in the immunocompetent individual with Candida-associated denture stomatitis Oral Microbiology and Immunology 2002 17 5 311 314
72. Mencacci A., Bacci A., Cenci E., Montagnoli C., Fiorucci S., Casagrande A., Flavell R. A., Bistoni F., Romani L., Interleukin 18 restores defective Th1 immunity to Candida albicans in caspase 1-deficient mice Infection and Immunity 2000 68 9 5126 5131
73. Mencacci A., Perruccio K., Bacci A., Cenci E., Benedetti R., Martelli M. F., Bistoni F., Coffman R., Velardi A., Romani L., Defective antifungal T-helper 1 (TH1) immunity in a murine model of allogeneic T-cell-depleted bone marrow transplantation and its restoration by treatment with TH2 cytokine antagonists Blood 2001 97 5 1483 1490
74. Liu J. Z., Pezeshki M., Raffatellu M., Th17 cytokines and host-pathogen interactions at the mucosa: dichotomies of help and harm Cytokine 2009 48 1-2 156 160
75. Levitz S. M., Th17 Cells Bounce off the Fungal Wall Cell Host and Microbe 2009 5 4 311 313
76. Lee J.-H., Lee J. Y., Park J. H., Jung H. S., Kim J. S., Kang S. S., Kim Y. S., Han Y., Immunoregulatory activity by daucosterol, a -sitosterol glycoside, induces protective Th1 immune response against disseminated Candidiasis in mice Vaccine 2007 25 19 3834 3840
77. Rosati E., Scaringi L., Cornacchione P., Fettucciari K., Sabatini R., Mezzasoma L., Benedetti C., Cianetti S., Rossi R., Marconi P., Activation of cytokine genes during primary and anamnestic immune response to inactivated C. albicans Immunology 1996 89 1 142 151
78. Mencacci A., Cenci E., Bacci A., Bistoni F., Romani L., Host immune reactivity determines the efficacy of combination immunotherapy and antifungal chemotherapy in candidiasis Journal of Infectious Diseases 2000 181 2 686 694
79. Netea M. G., Kullberg B. J., Van Der Meer J. W. M., Severely impaired IL-12/IL-18/IFN axis in patients with hyper IgE syndrome European Journal of Clinical Investigation 2005 35 11 718 721
80. Leigh J. E., Steele C., Wormley F. L. Jr., Luo W., Clark R. A., Gallaher W., Fidel P. L. Jr., Th1/Th2 cytokine expression in saliva of HIV-positive and HIV-negative individuals: a pilot study in HIV-positive individuals with oropharyngeal candidiasis Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology 1998 19 4 373 380
81. Ouyang W., Kolls J. K., Zheng Y., The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation Immunity 2008 28 4 454 467
82. Milner J. D., Brenchley J. M., Laurence A., Freeman A. F., Hill B. J., Elias K. M., Kanno Y., Spalding C., Elloumi H. Z., Paulson M. L., Davis J., Hsu A., Asher A. I., O'Shea J., Holland S. M., Paul W. E., Douek D. C., Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome Nature 2008 452 7188 773 776
83. Zhou M., Yang B., Ma R., Wu C., Memory Th-17 cells specific for C. albicans are persistent in human peripheral blood Immunology Letters 2008 118 1 72 81
84. De Luca A., Zelante T., D'Angelo C., Zagarella S., Fallarino F., Spreca A., Iannitti R. G., Bonifazi P., Renauld J.-C., Bistoni F., Puccetti P., Romani L., IL-22 defines a novel immune pathway of antifungal resistance Mucosal Immunology 2010 3 4 361 373
85. Rizzetto L., Kuka M., De Filippo C., Cambi A., Netea M. G., Beltrame L., Napolitani G., Torcia M. G., D'Oro U., Cavalieri D., Differential IL-17 production and mannan recognition contribute to fungal pathogenicity and commensalism The Journal of Immunology 2010 184 8 4258 4268
86. Acosta-Rodriguez E. V., Rivino L., Geginat J., Jarrossay D., Gattorno M., Lanzavecchia A., Sallusto F., Napolitani G., Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells Nature Immunology 2007 8 6 639 646
87. Eyerich K., Foerster S., Rombold S., Seidl H.-P., Behrendt H., Hofmann H., Ring J., Traidl-Hoffmann C., Patients with chronic mucocutaneous candidiasis exhibit reduced production of Th17-associated cytokines IL-17 and IL-22 Journal of Investigative Dermatology 2008 128 11 2640 2645
88. De Luca A., Montagnoli C., Zelante T., Bonifazi P., Bozza S., Moretti S., D'Angelo C., Vacca C., Boon L., Bistoni F., Puccetti P., Fallarino F., Romani L., Functional yet balanced reactivity to Candida albicans requires TRIF, MyD88, and IDO-dependent inhibition of Rorc The Journal of Immunology 2007 179 9 5999 6008
89. Agostini M., Cenci E., Pericolini E., Nocentini G., Bistoni G., Vecchiarelli A., Riccardi C., The glucocorticoid-induced tumor necrosis factor receptor-related gene modulates the response to Candida albicans infection Infection and Immunity 2005 73 11 7502 7508
90. Zaunders J. J., Munier M. L., Seddiki N., Pett S., Ip S., Bailey M., Xu Y., Brown K., Dyer W. B., Kim M., de Rose R., Kent S. J., Jiang L., Breit S. N., Emery S., Cunningham A. L., Cooper D. A., Kelleher A. D., High levels of human antigen-specific CD8+ T cells in peripheral blood revealed by stimulated coexpression of CD25 and CD134 (OX40) The Journal of Immunology 2009 183 4 2827 2836