An on-bead assay for the identification of non-natural peptides targeting the Androgen Receptor-cofactor interaction

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 1, 2011, Pages 306-311

  Göksel, Hülya ^a   Wasserberg, Dorothee ^a   Möcklinghoff, Sabine ^a,b   Araujo, Belen Vaz ^a   Brunsveld, Luc ^a,b  

^a CHEMICAL GENOMICS CENTRE OF THE MAX PLANCK SOCIETY   (Germany)

^b EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

Author keywords

Library synthesis; Nuclear receptors; Peptide chemistry

Indexed keywords

ANDROGEN RECEPTOR; CELL NUCLEUS RECEPTOR; LEUCYLLEUCYLGLYCYLLEUCYLTRYPTOPHYLVALYLSERYLSERYLSERYLGLYCINE; LEUCYLVALYLTYROSYLLEUCYLTYROSYLLEUCYLVALYLSERYLSERYLGLYCINE; PEPTIDE DERIVATIVE; PEPTIDE LIBRARY; SERYLSERYLARGINYLPHENYLALANYLGLUTAMYLSERYLLEUCYLPHENYLALANYLALANYLGLYCYLGLUTAMYLLYSYLGLUTAMYLSERYLARGINYLGLYCINE; SERYLVALYLPHENYLALANYLPHENYLALANYLGLYCYLPHENYLALANYLPHENYLALANYLSERYLSERYLGLYCINE; TYROSYLSERYLVALYLPHENYLALANYLVALYLLEUCYLTYROSYLSERYLSERYLGLYCINE; UNCLASSIFIED DRUG; VALYLGLYCYLPHENYLALANYLTRYPTOPHYLGLYCYLTRYPTOPHYLTRYPTOPHYLSERYLSERYLGLYCINE;

AMINO ACID ANALYSIS; AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; FLUORESCENCE MICROSCOPY; FLUORESCENCE POLARIZATION; HYDROPHOBICITY; LIGAND BINDING; PEPTIDE ANALYSIS; PEPTIDE SYNTHESIS; PHAGE DISPLAY; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PROTEIN TARGETING; RECEPTOR BINDING; SCREENING;

AMINO ACID SEQUENCE; FLUORESCENCE POLARIZATION; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; PEPTIDES; RECEPTORS, ANDROGEN;

EID: 78650728895     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.11.019     Document Type: Article

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