Cation-π interaction regulates ligand-binding affinity and signaling of integrin α4β7

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 50, 2010, Pages 21388-21393

  Pan, You Dong ^a   Zhang, Kun ^a   Qi, Jun Peng ^a   Yue, Jiao ^a   Springer, Timothy A ^b,c   Chen, Jian Feng ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATION; INTEGRIN; INTEGRIN ALPHA4BETA7; PAXILLIN; UNCLASSIFIED DRUG;

ARTICLE; CELL ADHESION; CONFORMATIONAL TRANSITION; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; CATIONS; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; INTEGRINS; LEUKOCYTE ROLLING; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION;

EID: 78650724558     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1015487107     Document Type: Article

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