Modulation of cell migration by integrin-mediated cytoskeletal linkages and ligand-binding affinity

Journal of Cell Biology

Volumn 134, Issue 6, 1996, Pages 1551-1562

  Huttenlocher, Anna ^a   Ginsberg, Mark H ^b   Horwitz, Alan F ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN;

ACTIN FILAMENT; ARTICLE; CELL INTERACTION; CELL MIGRATION; CYTOSKELETON; EMBRYO DEVELOPMENT; ENZYME SUBSTRATE; GENETIC TRANSFECTION; INTERMEDIATE FILAMENT; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR AFFINITY;

EID: 0029820264     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.134.6.1551     Document Type: Article

References (47)

1. Albelda, S.M., D.E. Mette, R. Stewart, L. Damjanovich, M. Herlyn, and C.A. Buck. 1991. Integrin distribution in malignant melanoma: association of the β3 subunit with tumor progression. Cancer Res. 50:6757-6764.
2. Alig, L., A. Edenhofer, P. Hadvary, M. Hurzeler, D. Knopp, M. Muller, B. Steiner, A. Trzeciak, and T. Weller. 1992. Low molecular weight, non-peptide fibrinogen receptor antagonists. J. Med. Chem. 35:4393-4407.
3. Brown, P.J., and R.L. Juliano. 1985. Selective inhibition of fibronectin-mediated cell adhesion by monoclonal antibodies to a cell-surface glycoprotein. Science (Wash. DC). 228:1448-1451.
4. Brown, P.J., and R.L. Juliano. 1988. Monoclonal antibodies to distinctive epitopes on the α and β subunits of the fibronectin receptor. Exp. Cell Res. 177:303-318.
5. Burridge, K., K. Fath, T. Kelly, G. Nuckolls, and C. Turner. 1988. Focal adhesions: Transmembrane junction between the extracellular matrix and the cytoskeleton. Annu. Rev. Cell Biol. 4:487-525.
6. Clark, E.A., and J.S. Brugge. 1995. Integrins and signal transduction pathways: the road taken. Science (Wash. DC). 268:233-239.
7. Damsky, C.H., and Z. Werb. 1992. Signal transduction by integrin receptors for extracellular matrix: cooperative processing of extracellular information. Curr. Opin. Cell Biol. 4:772-781.
8. Diamond, M.S., and T.A. Springer. 1994. The dynamic regulation of integrin adhesiveness. Curr. Biol. 4:506-517.
9. DiMilla, P., K. Barbee, and D. Lauffenburger. 1991. Mathematical model for the effects of adhesion and mechanics on cell migration speed. Biophys. J. 60:15-37.
10. DiMilla, P.A., J.A. Stone, J.A. Ouinn, S.M. Albelda, and D.A. Lauffenburger. 1993. Maximal migration of human smooth muscle cells on fibronectin and type IV collagen occurs at an intermediate attachment strength. J. Cell Biol. 122:729-737.
11. Duband, J., S. Dufour, S. Yamada, and K. Yamada. 1991. Neural crest cell migration induced by antibodies to β1 integrins. A tool for studying the roles of substratum molecular avidity and density in migration. J. Cell Sci. 98:517-532.
12. Dunlevy, J.R., and J.R. Couchman. 1993. Controlled induction of focal adhesion disassembly and migration in primary fibroblasts. J. Cell Sci. 105:489-500.
13. Dunlevy, J.R., and J.R. Couchman. 1995. Interleukin-8 induces motile behavior and loss of focal adhesions in primary fibroblasts. J. Cell Sci. 108:311-321.
14. Filardo, E.J., P.C. Brooks, S.L. Deming, C. Damsky, and D.A. Cheresh. 1995. Requirement of the NPXY motif in the integrin β3 subunit cytoplasmic tail for melanoma cell migration in vitro and in vivo. J. Cell Biol. 130:441-450.
15. Frelinger, A.L., X. Du, E.F. Plow, and M.H. Ginsberg. 1991. Monoclonal antibodies to ligand-occupied conformer of integrin αIIbβ3 (glycoprotein IIb-IIIa) alter receptor affinity, specificity and function. J. Biol. Chem. 266: 17106-17111.
16. Ginsberg, M.H., X. Du, and E.F. Plow. 1992. Inside-out integrin signaling. Curr. Opin. Cell Biol. 4:766-771.
17. Goodman, S., G. Risse, and K. van der Mark. 1989. The E8 subfragment of laminin promotes locomotion of myoblasts over extracellular matrix. J. Cell Biol. 109:799-809.
18. Hammarbach, J., J. McCarthy, S. Palm, and L. Furcht. 1988. Growth cone guidance by substrate-bound laminin pathways is correlated with neuron-to-pathway adhesivity. Dev. Biol. 126:29-39.
19. Hayashi, Y., A. Haimovich, D. Reszka, D. Boettiger, and A. Horwitz. 1990. Expression and function of chicken integrin β1 subunit and its cytoplasmic domain mutants in mouse NIH 3T3 cells. J. Cell Biol. 110:175-184.
20. Hughes, P., T. O'Toole, J. Ylanne, S. Shattil, and M. Ginsberg. 1995. The conserved membrane-proximal region of an integrin cytoplasmic domain specifies ligand binding affinity. J. Biol. Chem. 270:12411-12417.
21. Huttenlocher, A., R.S. Sandborg, and A.F. Horwitz. 1995. Adhesion in cell migration. Curr. Opin. Cell Biol. 7:697-706.
22. Hynes, R.O. 1992. Integrins: versatility, modulation and signaling in cell adhesion. Cell. 69:11-25.
23. Juliano, R.L., and S. Haskill. 1993. Signal transduction from the extracellular matrix. J. Cell Biol. 120:577-585.
24. Kassner, P.D., R. Alon, T.A. Springer, and M.E. Hemler. 1995. Specialized functional properties of the integrin α4 cytoplasmic domain. Mol. Biol. Chem. 6:661-674.
25. Kuijpers, T.W., E.P. Mul, M. Blom, N.L. Kovach, F.C.A. Gaeta, V. Tollefson, M.J. Elices, and J.M. Harlan. 1993. Freezing adhesion molecules in a state of high-avidity binding blocks eosinophil migration. J. Exp. Med. 178:279-284.
26. LaFlamme, S.E., S.K. Akiyama, and K.M. Yamada. 1992. Regulation of fibronectin receptor distribution. J. Cell Biol. 117:437-447.
27. Landegren, U. 1984. Measurement of cell numbers by means of the endogenous enzyme hexosaminidase. Applications to detection of lymphokines and cell surface antigens. J. Immunol. Methods. 67:379-388.
28. Lauffenburger, D.A., and A.F. Horwitz. 1996. Cell migration: a physically integrated molecular process. Cell. 84:359-369.
29. Lee, J., M. Leonard, T. Oliver, A. Ishihara, and K. Jacobson. 1994. Traction forces generated by locomoting keratocytes. J. Cell Biol. 127:1957-1964.
30. Loftus, J.C., T.E. O'Toole, E.F. Plow, A. Glass, A.L. Frelinger, and M.H. Ginsberg. 1990. A β3 integrin mutation abolishes ligand binding and alters divalent cation-dependent conformation. Science (Wash. DC). 249:915-918.
31. Marcantonio, E.E., J. Guan, J.E. Trevithick, and R.O. Hynes. 1990. Mapping of the functional determinanats of the integrin beta-1 cytoplasmic domain by site-directed mutagenesis. Cell Regul. 1:597-604.
32. Matsumoto, K., T. Nakamura, and R.H. Kramer. 1994. Hepatocyte growth factor/scatter factor induces tyrosine phosphorylation of focal adhesion kinase (p125FAK) and promotes migration and invasion by oral squamous cell carcinoma cells. J. Biol. Chem., 269:31807-31813.
33. McDonald, J.A., B.J. Quade, T.J. Broekelmann, R. LaChance, K. Forsman, E. Hasegawa, and S.K. Akiyama. 1987. Fibronectin's cell adhesive domain and an amino-terminal matrix assembly domain participate in its assembly into fibroblast pericellular matrix. J. Biol. Chem. 262:2957-2967.
34. Murphy-Ullrich, J.E. 1995. Anti-adhesive proteins of the extracellular matrix: thrombospondin, tenascin and SPARC. Trends Glycosci. Glycotechnol. 7: 89-100.
35. Murphy-Ullrich, J.E., and M. Hook. 1989. Thrombospondin modulates focal adhesions in endothelial cells. J. Cell Biol. 109:1309-1319.
36. O'Toole, T.E., J.C. Loftus, E.F. Plow, A. Glass, J.R. Harper, and M.H. Ginsberg. 1989. Efficient surface expression of platelet GPIIb-IIIa requires both subunits. Blood. 74:14-18.
37. O'Toole, T.E., J.C. Loftus, X. Du, A.A. Glass, Z.M. Ruggeri, S.J. Shattil, E.F. Plow, and M.H. Ginsberg. 1990. Affinity modulation for the αIIbβ3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor. Cell Regul. 1: 883-893.
38. O'Toole, T.E., Y. Katagiri, R.J. Faull, K. Peter, R. Tamura, V. Quaranta, J. Loftus, S.J. Shattil, and M.H. Ginsberg. 1994. Integrin cytoplasmic domains mediate inside-out signal transduction. J. Cell Biol. 124:1047-1059.
39. 5 cytoplasmic domains in subcellular localization, cell proliferation, and cell migration. J. Cell Biol. 125:447-460.
40. Plow, E.F., R.P. McEver, B.S. Coller, V.L. Woods, G.A. Marguerie, and M.H. Ginsberg. 1985. Related binding mechanisms for fibrinogen, fibronectin, von Willebrand factor and thrombospondin on thrombin-stimulated human platelets. Blood. 66:724-727.
41. Reszka, A.A., Y. Hayashi, and A.F. Horwitz. 1992. Identification of amino acid sequences in the integrin β1 cytoplasmic domain implicated in cytoskeletal association. J. Cell Biol. 117:1321-1330.
42. Schmidt, C.E., A.F. Horwitz, D.A. Lauffenburger, and M.P. Sheetz. 1993. Integrin cytoskeletal interactions in migrating fibroblasts are dynamic, asymmetric, and regulated. J. Cell Biol. 123:977-991.
43. Springer, T.A. 1995. Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration. Annu. Rev. Physiol. .57:827-872.
44. Stossel, T.P. 1993. On the crawling of animal cells. Science (Wash. DC). 260: 1086-1094.
45. Woods, V.L., E.H. Oh, D. Mason, and R. McMillan. 1984. Autoantibodies against the platelets glycoprotein IIb/IIIa complex in patients with chronic ITP. Blood. 63:368-375.
46. Wu, C., V.M. Keivens, T.E. O'Toole, J.A. McDonald, and M.H. Ginsberg. 1995. Integrin activation and cytoskeletal interaction are essential for the assembly of a fibronectin matrix. Cell. 83:715-724.
47. Ylänne, J., Y. Chen, T.E. O'Toole, J.C. Loftus, Y. Takada, and M.H. Ginsberg. 1993. Distinct functions of integrin α and β subunit cytoplasmic domains in cell spreading and formation of focal adhesions. J. Cell Biol. 122:223-233.