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Volumn 24, Issue 10, 2009, Pages 1223-1232

Analysis of NQO1 polymorphisms and p53 protein expression in patients with hepatocellular carcinoma

Author keywords

Hepatocellular carcinoma; NAD(P)H; P53 gene; Quinone oxidoreductase 1 (NQO1)

Indexed keywords

NQO1 PROTEIN, HUMAN; PROTEIN P53; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

EID: 78650707027     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (16)

References (41)
  • 1
    • 33645996345 scopus 로고    scopus 로고
    • Up-regulation of NAD(P)H quinone oxidoreductase 1 during human liver injury
    • Aleksunes L.M., Goedken M. and Manautou J.E. (2006). Up-regulation of NAD(P)H quinone oxidoreductase 1 during human liver injury. World J. Gastroenterol. 12, 1937-1940.
    • (2006) World J. Gastroenterol , vol.12 , pp. 1937-1940
    • Aleksunes, L.M.1    Goedken, M.2    Manautou, J.E.3
  • 3
    • 0036791010 scopus 로고    scopus 로고
    • Mdm-2 and ubiquitin-independent p53 proteasomal degradation regulated by NQO1
    • Asher G., Lotem J., Sachs L., Kahana C. and Shaul Y. (2002b). Mdm-2 and ubiquitin-independent p53 proteasomal degradation regulated by NQO1. Proc. Natl. Acad. Sci. USA 99, 13125-13130.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 13125-13130
    • Asher, G.1    Lotem, J.2    Sachs, L.3    Kahana, C.4    Shaul, Y.5
  • 5
    • 0038796599 scopus 로고    scopus 로고
    • Induction of NAD(P)H quinone: Oxidoreductase1 inhibits carcinogeninduced aberrant crypt foci in colons of Sprague-Dawley rats
    • Begleiter A., Sivananthan K., Curphey T.J. and Bird R.P. (2003). Induction of NAD(P)H quinone: oxidoreductase1 inhibits carcinogeninduced aberrant crypt foci in colons of Sprague-Dawley rats. Cancer Epidemiol. Biomarkers Prev. 12, 566-572.
    • (2003) Cancer Epidemiol. Biomarkers Prev , vol.12 , pp. 566-572
    • Begleiter, A.1    Sivananthan, K.2    Curphey, T.J.3    Bird, R.P.4
  • 6
    • 33744546476 scopus 로고    scopus 로고
    • In vivo relevance of two critical levels for NAD(P)H:Quinone oxidoreductase (NQO1)-mediated cellular protection against electrophile toxicity found in vitro
    • de Haan L.H., Pot G.K., Aarts J.M., Rietjens I.M. and Alink G.M. (2006). In vivo relevance of two critical levels for NAD(P)H:quinone oxidoreductase (NQO1)-mediated cellular protection against electrophile toxicity found in vitro. Toxicol. In Vitro 20, 594-600.
    • (2006) Toxicol. In Vitro , vol.20 , pp. 594-600
    • de Haan, L.H.1    Pot, G.K.2    Aarts, J.M.3    Rietjens, I.M.4    Alink, G.M.5
  • 7
    • 3242742185 scopus 로고    scopus 로고
    • DT-diaphorase: A target for new anticancer drugs
    • Danson S., Ward T.H., Butler J. and Ranson M. (2004). DT-diaphorase: a target for new anticancer drugs. Cancer Treat. 30, 437-449.
    • (2004) Cancer Treat , vol.30 , pp. 437-449
    • Danson, S.1    Ward, T.H.2    Butler, J.3    Ranson, M.4
  • 8
    • 33748275681 scopus 로고    scopus 로고
    • The p53 tumor suppressor participates in multiple cell cycle checkpoints
    • Giono L.E. and Manfredi J.J. (2006) The p53 tumor suppressor participates in multiple cell cycle checkpoints. J. Cell Physiol. 209, 13-20.
    • (2006) J. Cell Physiol , vol.209 , pp. 13-20
    • Giono, L.E.1    Manfredi, J.J.2
  • 9
    • 34347225583 scopus 로고    scopus 로고
    • NRH:Quinone oxidoreductase 2 and NAD(P)H:Quinone oxidoreductase 1 protect tumor suppressor p53 against 20s proteasomal degradation leading to stabilization and activation of p53
    • Gong X., Kole L., Iskander K. and Jaiswal A.K. (2007) NRH:quinone oxidoreductase 2 and NAD(P)H:quinone oxidoreductase 1 protect tumor suppressor p53 against 20s proteasomal degradation leading to stabilization and activation of p53. Cancer Res. 67, 5380-5388.
    • (2007) Cancer Res , vol.67 , pp. 5380-5388
    • Gong, X.1    Kole, L.2    Iskander, K.3    Jaiswal, A.K.4
  • 10
    • 0033384268 scopus 로고    scopus 로고
    • NAD(P)H quinone oxidoreductase 1 codon 609 polymorphism and its association to colorectal cancer
    • Harth V., Donat S., Ko Y., Abel J., Vetter H. and Bruning T. (2000) NAD(P)H quinone oxidoreductase 1 codon 609 polymorphism and its association to colorectal cancer. Arch. Toxicol. 73, 528-531.
    • (2000) Arch. Toxicol , vol.73 , pp. 528-531
    • Harth, V.1    Donat, S.2    Ko, Y.3    Abel, J.4    Vetter, H.5    Bruning, T.6
  • 11
    • 33645214725 scopus 로고    scopus 로고
    • Review of genetic and epigenetic alterations in hepatocarcinogenesis
    • Herath N.I., Leggett B.A. and MacDonald G.A. (2006) Review of genetic and epigenetic alterations in hepatocarcinogenesis. J. Gastroenterol. Hepatol. 21, 15-21.
    • (2006) J. Gastroenterol. Hepatol , vol.21 , pp. 15-21
    • Herath, N.I.1    Leggett, B.A.2    Macdonald, G.A.3
  • 12
    • 0032988319 scopus 로고    scopus 로고
    • Regulation of p53 protein function through alterations in protein-folding pathways
    • Hupp T.R. (1999) Regulation of p53 protein function through alterations in protein-folding pathways. Cell Mol. Life Sci. 55, 88-95.
    • (1999) Cell Mol. Life Sci , vol.55 , pp. 88-95
    • Hupp, T.R.1
  • 13
    • 18044371620 scopus 로고    scopus 로고
    • Genetic variants of TP53 and EPHX1 in Leber's hereditary optic neuropathy and their relationship to age at onset
    • Ishikawa K., Funayama T., Ohde H., Inagaki Y. and Mashima Y. (2005). Genetic variants of TP53 and EPHX1 in Leber's hereditary optic neuropathy and their relationship to age at onset. Jpn. J. Ophthalmol. 49, 121-6.
    • (2005) Jpn. J. Ophthalmol , vol.49 , pp. 121-126
    • Ishikawa, K.1    Funayama, T.2    Ohde, H.3    Inagaki, Y.4    Mashima, Y.5
  • 14
    • 20444396613 scopus 로고    scopus 로고
    • Quinone oxidoreductases in protection against myelogenous hyperplasia and benzene toxicity
    • Iskander K. and Jaiswal A.K. (2005). Quinone oxidoreductases in protection against myelogenous hyperplasia and benzene toxicity. Chem. Biol. Interact. 153-154, 147-157.
    • (2005) Chem. Biol. Interact , vol.153-154 , pp. 147-157
    • Iskander, K.1    Jaiswal, A.K.2
  • 15
    • 0028653618 scopus 로고
    • NAD(P)H:Quinone oxidoreductase1 (DT-diaphorase): Expression, regulation, and role in cancer
    • Joseph P., Xie T., Xu Y. and Jaiswal A.K. (1994). NAD(P)H:quinone oxidoreductase1 (DT-diaphorase): expression, regulation, and role in cancer. Oncol. Res. 6, 525-532.
    • (1994) Oncol. Res , vol.6 , pp. 525-532
    • Joseph, P.1    Xie, T.2    Xu, Y.3    Jaiswal, A.K.4
  • 16
    • 0034662467 scopus 로고    scopus 로고
    • Role of NAD(P)H:Quinone oxidoreductase 1 (DT diaphorase) in protection against quinone toxicity
    • Joseph P., Long D.J., Klein-Szanto A.J. and Jaiswal A.K. (2000). Role of NAD(P)H:quinone oxidoreductase 1 (DT diaphorase) in protection against quinone toxicity. Biochem. Pharmacol. 60, 207-214.
    • (2000) Biochem. Pharmacol , vol.60 , pp. 207-214
    • Joseph, P.1    Long, D.J.2    Klein-Szanto, A.J.3    Jaiswal, A.K.4
  • 17
  • 18
    • 38449084834 scopus 로고    scopus 로고
    • Identification of differential expression of genes in hepatocellular carcinoma by suppression subtractive hybridization combined cDNA microarray
    • Liu Y., Zhu X., Zhu J., Liao S., Tang Q., Liu K., Guan X., Zhang J. and Feng Z. (2007). Identification of differential expression of genes in hepatocellular carcinoma by suppression subtractive hybridization combined cDNA microarray. Oncol. Reports 18, 943-951.
    • (2007) Oncol. Reports , vol.18 , pp. 943-951
    • Liu, Y.1    Zhu, X.2    Zhu, J.3    Liao, S.4    Tang, Q.5    Liu, K.6    Guan, X.7    Zhang, J.8    Feng, Z.9
  • 19
    • 0034326245 scopus 로고    scopus 로고
    • NAD(P)H:Quinone oxidoreductase 1 deficiency increases susceptibility to benzo(a)pyrene-induced mouse skin carcinogenesis
    • Long D.J 2nd., Waikel R.L., Wang X.J., Perlaky L., Roop D.R. and Jaiswal A.K. (2000). NAD(P)H:quinone oxidoreductase 1 deficiency increases susceptibility to benzo(a)pyrene-induced mouse skin carcinogenesis. Cancer Res. 60, 5913-5925.
    • (2000) Cancer Res , vol.60 , pp. 5913-5925
    • Long II, D.J.1    Waikel, R.L.2    Wang, X.J.3    Perlaky, L.4    Roop, D.R.5    Jaiswal, A.K.6
  • 20
    • 0035422794 scopus 로고    scopus 로고
    • NAD(P)H:Quinone oxidoreductase 1 deficiency and increased susceptibility to 7,12-dimethylbenz[a]-anthracene-induced carcinogenesis in mouse skin
    • Long D.J 2nd., Waikel R.L., Wang X.J., Roop D.R. and Jaiswal A.K. (2001). NAD(P)H:quinone oxidoreductase 1 deficiency and increased susceptibility to 7,12-dimethylbenz[a]-anthracene-induced carcinogenesis in mouse skin. J. Natl. Cancer Inst. 93, 1166-1170.
    • (2001) J. Natl. Cancer Inst , vol.93 , pp. 1166-1170
    • Long II, D.J.1    Waikel, R.L.2    Wang, X.J.3    Roop, D.R.4    Jaiswal, A.K.5
  • 21
  • 22
    • 33644851998 scopus 로고    scopus 로고
    • Increased levels of NAD(P)H: Quinone oxidoreductase 1 (NQO1) in pancreatic tissues from smokers and pancreatic adenocarcinomas: A potential biomarker of early damage in the pancreas
    • Lyn-Cook B.D., Yan-Sanders Y., Moore S., Taylor S., Word B. and Hammons G.J. (2006). Increased levels of NAD(P)H: quinone oxidoreductase 1 (NQO1) in pancreatic tissues from smokers and pancreatic adenocarcinomas: A potential biomarker of early damage in the pancreas. Cell Biol. Toxicol. 22, 73-80.
    • (2006) Cell Biol. Toxicol , vol.22 , pp. 73-80
    • Lyn-Cook, B.D.1    Yan-Sanders, Y.2    Moore, S.3    Taylor, S.4    Word, B.5    Hammons, G.J.6
  • 23
    • 24744447821 scopus 로고    scopus 로고
    • The role of poly(ADP-ribose) in the DNA damage signaling network
    • Malanga M. and Althaus F.R. (2005). The role of poly(ADP-ribose) in the DNA damage signaling network. Biochem. Cell Biol. 83, 354-364.
    • (2005) Biochem. Cell Biol , vol.83 , pp. 354-364
    • Malanga, M.1    Althaus, F.R.2
  • 24
    • 0034934322 scopus 로고    scopus 로고
    • Analysis of differentially expressed genes in human hepatocellular carcinoma using suppression subtractive hybridization
    • Miyasaka Y., Enomoto N. and Nagayama K. (2001). Analysis of differentially expressed genes in human hepatocellular carcinoma using suppression subtractive hybridization. Br. J. Cancer 85, 228-234.
    • (2001) Br. J. Cancer , vol.85 , pp. 228-234
    • Miyasaka, Y.1    Enomoto, N.2    Nagayama, K.3
  • 25
    • 0141453688 scopus 로고    scopus 로고
    • Clinicopathologic significance of genetic alterations in hepatocellular carcinoma
    • Pang A., Ng I.O., Fan S.T. and Kwong Y.L. (2003). Clinicopathologic significance of genetic alterations in hepatocellular carcinoma. Cancer Genet. Cytogenet. 146, 8-15.
    • (2003) Cancer Genet. Cytogenet , vol.146 , pp. 8-15
    • Pang, A.1    Ng, I.O.2    Fan, S.T.3    Kwong, Y.L.4
  • 28
    • 0031304246 scopus 로고    scopus 로고
    • DT-diaphorase: Possible roles in cancer chemotherapy and carcinogenesis
    • Rauth A.M., Goldberg Z. and Misra V. (1997). DT-diaphorase: possible roles in cancer chemotherapy and carcinogenesis. Oncol Res. 9, 339-349.
    • (1997) Oncol Res , vol.9 , pp. 339-349
    • Rauth, A.M.1    Goldberg, Z.2    Misra, V.3
  • 29
    • 15244350514 scopus 로고    scopus 로고
    • An association between a NQO1 genetic polymorphism and risk of lung cancer
    • Saldivar S.J., Wang Y., Zhao H., Shao L., Lin J., Spitz M.R. and Wu X. (2005). An association between a NQO1 genetic polymorphism and risk of lung cancer. Mutat. Res. 582, 71-78.
    • (2005) Mutat. Res , vol.582 , pp. 71-78
    • Saldivar, S.J.1    Wang, Y.2    Zhao, H.3    Shao, L.4    Lin, J.5    Spitz, M.R.6    Wu, X.7
  • 31
    • 0025248106 scopus 로고
    • Cytosolic NAD(P)H:(quinoneacceptor) oxidoreductase in human normal and tumor tissue: Effects of cigarette smoking and alcohol
    • Schlager J.J. and Powis G. (1990). Cytosolic NAD(P)H:(quinoneacceptor) oxidoreductase in human normal and tumor tissue: effects of cigarette smoking and alcohol. Int. J. Cancer 45, 403-409.
    • (1990) Int. J. Cancer , vol.45 , pp. 403-409
    • Schlager, J.J.1    Powis, G.2
  • 32
    • 0037714871 scopus 로고    scopus 로고
    • Is p53 gene mutation an indicatior of the biological behaviors of recurrence of hepatocellular carcinoma
    • Sheen I.S., Jeng K.S. and Wu J.Y. (2003). Is p53 gene mutation an indicatior of the biological behaviors of recurrence of hepatocellular carcinoma? World J. Gastroenterol. 9, 1202-1207.
    • (2003) World J. Gastroenterol , vol.9 , pp. 1202-1207
    • Sheen, I.S.1    Jeng, K.S.2    Wu, J.Y.3
  • 33
    • 0033801337 scopus 로고    scopus 로고
    • Immunodetection of NAD(P)H:Quinone oxidoreductase 1 (NQO1) in human tissues
    • Siegel D. and Ross D. (2000). Immunodetection of NAD(P)H:quinone oxidoreductase 1 (NQO1) in human tissues. Free Radic. Biol. Med. 29, 246-253.
    • (2000) Free Radic. Biol. Med , vol.29 , pp. 246-253
    • Siegel, D.1    Ross, D.2
  • 34
    • 0035135690 scopus 로고    scopus 로고
    • Rapid polyubiquitination and proteasomal degradation of a mutant form of NAD(P)H:Quinone oxidoreductase 1
    • Siegel D., Anwar A., Winski S.L., Kepa J.K., Zolman K.L. and Ross D. (2001). Rapid polyubiquitination and proteasomal degradation of a mutant form of NAD(P)H:quinone oxidoreductase 1. Mol. Pharmacol. 59, 263-268.
    • (2001) Mol. Pharmacol , vol.59 , pp. 263-268
    • Siegel, D.1    Anwar, A.2    Winski, S.L.3    Kepa, J.K.4    Zolman, K.L.5    Ross, D.6
  • 35
    • 0035085998 scopus 로고    scopus 로고
    • p53 Signaling and cell cycle checkpoints
    • Stewart Z.A. and Pietenpol J.A. (2001). p53 Signaling and cell cycle checkpoints. Chem. Res. Toxicol. 14, 243-263.
    • (2001) Chem. Res. Toxicol , vol.14 , pp. 243-263
    • Stewart, Z.A.1    Pietenpol, J.A.2
  • 36
    • 0036156337 scopus 로고    scopus 로고
    • Differential gene expression of NAD(P)H: Quinone Oxidoreductase and NRH:Quinone Oxidoreductase in human hepatocellular and biliary tissue
    • Strassburg A., Strassburg C.P., Manns M.P. and Tukey R.H. (2002). Differential gene expression of NAD(P)H: Quinone Oxidoreductase and NRH:Quinone Oxidoreductase in human hepatocellular and biliary tissue. Mol. Pharmacol. 61, 320-325.
    • (2002) Mol. Pharmacol , vol.61 , pp. 320-325
    • Strassburg, A.1    Strassburg, C.P.2    Manns, M.P.3    Tukey, R.H.4
  • 37
    • 0036322465 scopus 로고    scopus 로고
    • Contribution of the NQO1 and GSTT1 polymorphisms to lung adenocarcinoma susceptibility
    • Sunga N., Kohno T. and Yanagitani N. (2002). Contribution of the NQO1 and GSTT1 polymorphisms to lung adenocarcinoma susceptibility. Cancer Epidemiol. Biomarkers Prev. 11, 730-738.
    • (2002) Cancer Epidemiol. Biomarkers Prev , vol.11 , pp. 730-738
    • Sunga, N.1    Kohno, T.2    Yanagitani, N.3
  • 38
    • 34249792074 scopus 로고    scopus 로고
    • Characterization of resistance to bromobenzene-induced hepatotoxicity by microarray
    • Tanaka K., Kiyosawa N., Watanabe K. and Manabe S. (2007). Characterization of resistance to bromobenzene-induced hepatotoxicity by microarray. J. Toxicol. Sci. 32, 129-134.
    • (2007) J. Toxicol. Sci , vol.32 , pp. 129-134
    • Tanaka, K.1    Kiyosawa, N.2    Watanabe, K.3    Manabe, S.4
  • 40
    • 17244378011 scopus 로고    scopus 로고
    • Inhibition of NAD(P)H:Quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin
    • Tsvetkov P., Asher G., Reiss V., Shaul Y., Sachs L. and Lotem J. (2005). Inhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin. Proc. Natl. Acad. Sci. USA 102, 5535-5540.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 5535-5540
    • Tsvetkov, P.1    Asher, G.2    Reiss, V.3    Shaul, Y.4    Sachs, L.5    Lotem, J.6
  • 41
    • 12444342653 scopus 로고    scopus 로고
    • Association of NAD(P)H: Quinone oxidoreductase 1 (NQO1) C609T polymorphism with esophageal squamous cell carcinoma in a German Caucasian and a northern Chinese population
    • Zhang J., Schulz W.A., Li Y., Wang R., Zotz R., Wen D., Siegel D., Ross D., Gabbert H.E. and Sarbia M. (2003). Association of NAD(P)H: quinone oxidoreductase 1 (NQO1) C609T polymorphism with esophageal squamous cell carcinoma in a German Caucasian and a northern Chinese population. Carcinogenesis 24, 905-909.
    • (2003) Carcinogenesis , vol.24 , pp. 905-909
    • Zhang, J.1    Schulz, W.A.2    Li, Y.3    Wang, R.4    Zotz, R.5    Wen, D.6    Siegel, D.7    Ross, D.8    Gabbert, H.E.9    Sarbia, M.10


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