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Volumn 22, Issue 2, 2006, Pages 73-80

Increased levels of NAD(P)H: Quinone oxidoreductase 1 (NQO1) in pancreatic tissues from smokers and pancreatic adenocarcinomas: A potential biomarker of early damage in the pancreas

Author keywords

NQO1; Pancreatic; Pancreatitis; Polymorphism; Smoking

Indexed keywords

BIOLOGICAL MARKER; CYTOSINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); THYMINE;

EID: 33644851998     PISSN: 07422091     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10565-006-0156-3     Document Type: Article
Times cited : (42)

References (37)
  • 1
    • 0031426390 scopus 로고    scopus 로고
    • Metabolic activation of aromatic amines by human pancreas
    • Anderson KE, Mammons GJ, Kadlubar FF, et al. Metabolic activation of aromatic amines by human pancreas. Carcinogenesis. 1997;18:1085-92.
    • (1997) Carcinogenesis , vol.18 , pp. 1085-1092
    • Anderson, K.E.1    Mammons, G.J.2    Kadlubar, F.F.3
  • 2
    • 0029056792 scopus 로고
    • Pancreatitis is a risk factor for pancreatic cancer
    • Bansal P, Sonnenberg A. Pancreatitis is a risk factor for pancreatic cancer. Gastronenterology. 1995;109:247-51.
    • (1995) Gastronenterology , vol.109 , pp. 247-251
    • Bansal, P.1    Sonnenberg, A.2
  • 4
    • 0035087573 scopus 로고    scopus 로고
    • Increased expression of iNOS and c-fos via regulation of protein tyrosine phosphorylation and MEK1/ERK2 proteins in terminal bronchiole lesions in the lungs of rats exposed to cigarette smoke
    • Chang W-C, Lee Y-C, Liu C-L, et al. Increased expression of iNOS and c-fos via regulation of protein tyrosine phosphorylation and MEK1/ERK2 proteins in terminal bronchiole lesions in the lungs of rats exposed to cigarette smoke. Arch Toxicol. 2001;75:28-35.
    • (2001) Arch Toxicol , vol.75 , pp. 28-35
    • Chang, W.-C.1    Lee, Y.-C.2    Liu, C.-L.3
  • 6
    • 0032804227 scopus 로고    scopus 로고
    • Association of NAD(P)H:quinone oxidoreductase (NQO1) null with the numbers of basal cell carcinomas: Use of a multi-variate model to rank the relative importance of this polymorphism and those at other relevant loci
    • Lond
    • Clairmont A, Sies H, Ramachandran S, et al. Association of NAD(P)H:quinone oxidoreductase (NQO1) null with the numbers of basal cell carcinomas: use of a multi-variate model to rank the relative importance of this polymorphism and those at other relevant loci. Carcinogenesis (Lond). 1999;20:1235-40.
    • (1999) Carcinogenesis , vol.20 , pp. 1235-1240
    • Clairmont, A.1    Sies, H.2    Ramachandran, S.3
  • 7
    • 0028114942 scopus 로고
    • Cytosolic activation of aromatic and heterocyclic amines: Inhibition by dicoumarol and enhancement in viral hepatitis B
    • De Flora S, Bennicelli C, D'Agostini F, Izzotti A, Camoirano A. Cytosolic activation of aromatic and heterocyclic amines: inhibition by dicoumarol and enhancement in viral hepatitis B. Environ Health Perspect. 1994;6:69-74.
    • (1994) Environ Health Perspect , vol.6 , pp. 69-74
    • De Flora, S.1    Bennicelli, C.2    D'Agostini, F.3    Izzotti, A.4    Camoirano, A.5
  • 8
    • 0033643459 scopus 로고    scopus 로고
    • Antioxidant regulation of genes encoding enzymes that detoxify xenobiotics and carcinogens
    • Dhakshinamoorthy S, Long DJ II, Jaiswal AK. Antioxidant regulation of genes encoding enzymes that detoxify xenobiotics and carcinogens. Curr Top Cellul Regul. 2000;36:201-6.
    • (2000) Curr Top Cellul Regul , vol.36 , pp. 201-206
    • Dhakshinamoorthy, S.1    Long II, D.J.2    Jaiswal, A.K.3
  • 9
    • 0037093947 scopus 로고    scopus 로고
    • Annual report to the nation on the status of cancer, 1973-1999, featuring implications of age and aging on U.S. cancer burden
    • Edwards BK, Howe HL, Ries LA, et al. Annual report to the nation on the status of cancer, 1973-1999, featuring implications of age and aging on U.S. cancer burden. Cancer. 2002;94:2766-92.
    • (2002) Cancer , vol.94 , pp. 2766-2792
    • Edwards, B.K.1    Howe, H.L.2    Ries, L.A.3
  • 10
    • 0029805031 scopus 로고    scopus 로고
    • A prospective study of cigarette smoking and the risk of pancreatic cancer
    • Fuchs CS, Colditz GA, Stampfer MJ, et al. A prospective study of cigarette smoking and the risk of pancreatic cancer. Arch Intern Med. 1996;156:2255-60.
    • (1996) Arch Intern Med , vol.156 , pp. 2255-2260
    • Fuchs, C.S.1    Colditz, G.A.2    Stampfer, M.J.3
  • 11
    • 0029096688 scopus 로고
    • Increased DT-diaphorase activity in transformed and tumorigenic pancreatic acinar cells
    • Hammons GJ, Warren GJ, Blann E, Nichols J, Lyn-Cook BD. Increased DT-diaphorase activity in transformed and tumorigenic pancreatic acinar cells. Cancer Lett. 1995;96:9-14.
    • (1995) Cancer Lett , vol.96 , pp. 9-14
    • Hammons, G.J.1    Warren, G.J.2    Blann, E.3    Nichols, J.4    Lyn-Cook, B.D.5
  • 13
    • 9844256095 scopus 로고    scopus 로고
    • Ethnic variation in the prevalence of a common NAD(P)H quinone oxidoreductase polymorphism and its implications for anti-cancer chemotherapy
    • Kelsey KT, Ross D, Traver RD, et al. Ethnic variation in the prevalence of a common NAD(P)H quinone oxidoreductase polymorphism and its implications for anti-cancer chemotherapy. Br J Cancer. 1997;76:852-4.
    • (1997) Br J Cancer , vol.76 , pp. 852-854
    • Kelsey, K.T.1    Ross, D.2    Traver, R.D.3
  • 14
    • 0016609185 scopus 로고
    • Enzyme histochemical pattern in human tumours. II. Oxidoreductases in carcinoma of the colon and the breast
    • Koudstaal J, Makkink B, Overdiep SH. Enzyme histochemical pattern in human tumours. II. Oxidoreductases in carcinoma of the colon and the breast. Eur J Cancer. 1975;11:111-5.
    • (1975) Eur J Cancer , vol.11 , pp. 111-115
    • Koudstaal, J.1    Makkink, B.2    Overdiep, S.H.3
  • 15
    • 0029859863 scopus 로고    scopus 로고
    • DT-diaphorase maintains the reduced state of ubiquinones in lipid vesicles thereby promoting their antioxidant function
    • Landi L, Fiorentini D, Galli MC, Segura-Aguilar J, Beyer RE. DT-diaphorase maintains the reduced state of ubiquinones in lipid vesicles thereby promoting their antioxidant function. Free Radical Biol Med. 1997;22:329-35.
    • (1997) Free Radical Biol Med , vol.22 , pp. 329-335
    • Landi, L.1    Fiorentini, D.2    Galli, M.C.3    Segura-Aguilar, J.4    Beyer, R.E.5
  • 16
    • 0033564977 scopus 로고    scopus 로고
    • Prevalence of the inactivating 609C→T polymorphism in the NAD(P)H:quinone oxidoreductase (NQO1) gene in patients with primary and therapy-related myeloid leukemia
    • Larson RA, Wang Y, Banerjee M, et al. Prevalence of the inactivating 609C→T polymorphism in the NAD(P)H:quinone oxidoreductase (NQO1) gene in patients with primary and therapy-related myeloid leukemia. Blood. 1999;94:803-7.
    • (1999) Blood , vol.94 , pp. 803-807
    • Larson, R.A.1    Wang, Y.2    Banerjee, M.3
  • 17
    • 0036224657 scopus 로고    scopus 로고
    • A prospective study of cigarette smoking and pancreatic cancer in Japan
    • Lin Y, Tamakoshi A, Kawamura T, et al. A prospective study of cigarette smoking and pancreatic cancer in Japan. Cancer Causes Control. 2002;13:249-54.
    • (2002) Cancer Causes Control , vol.13 , pp. 249-254
    • Lin, Y.1    Tamakoshi, A.2    Kawamura, T.3
  • 18
    • 0038179900 scopus 로고    scopus 로고
    • Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer
    • Logsdon CD, Simeone DM, Binkley C, et al. Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer. Cancer Res. 2003;63:2649-57.
    • (2003) Cancer Res , vol.63 , pp. 2649-2657
    • Logsdon, C.D.1    Simeone, D.M.2    Binkley, C.3
  • 20
    • 0026700546 scopus 로고
    • Elevated DT-diaphorase activity and messenger RNA content in human non-small cell lung carcinoma: Relationship to the response of lung tumour xenografts to mitomycin C
    • Malkinson AM, Siegel D, Forrest GL, et al. Elevated DT-diaphorase activity and messenger RNA content in human non-small cell lung carcinoma: relationship to the response of lung tumour xenografts to mitomycin C. Cancer Res. 1992;52:4752-7.
    • (1992) Cancer Res , vol.52 , pp. 4752-4757
    • Malkinson, A.M.1    Siegel, D.2    Forrest, G.L.3
  • 21
    • 0028964121 scopus 로고
    • Expression of c-fos in quiescent Swiss 3T3 cell exposed to aqueous cigarette smoke fractions
    • Muller T. Expression of c-fos in quiescent Swiss 3T3 cell exposed to aqueous cigarette smoke fractions. Cancer Res. 1995;55:1927-32.
    • (1995) Cancer Res , vol.55 , pp. 1927-1932
    • Muller, T.1
  • 22
    • 48549110345 scopus 로고
    • Cytosol-mediated reduction of resorufin: A method for measuring quinone oxidoreductase
    • Nims RW, Prough RA, Lubet RA. Cytosol-mediated reduction of resorufin: a method for measuring quinone oxidoreductase. Arch Biochem Biophys. 1984;229:459-65.
    • (1984) Arch Biochem Biophys , vol.229 , pp. 459-465
    • Nims, R.W.1    Prough, R.A.2    Lubet, R.A.3
  • 24
    • 0000028560 scopus 로고    scopus 로고
    • Guengerich FP, Sipes IG, McQueen CA, Gandolfi AJ, eds. New York: Elsevier
    • Ross D. Quinone reductases. In: Guengerich FP, Sipes IG, McQueen CA, Gandolfi AJ, eds. Vol. 3. New York: Elsevier; 1997:179-7.
    • (1997) Quinone Reductases , vol.3 , pp. 179-187
    • Ross, D.1
  • 25
    • 0027295491 scopus 로고
    • DT-diaphorase in activation and detoxification of quinones. Bioreductive activation of mitomycin C
    • Ross D, Seigel D, Geall H, Prakash AS, Mulcahy RT, Gibson NW. DT-diaphorase in activation and detoxification of quinones. Bioreductive activation of mitomycin C. Cancer Metastasis Rev. 1993;12:83-101.
    • (1993) Cancer Metastasis Rev , vol.12 , pp. 83-101
    • Ross, D.1    Seigel, D.2    Geall, H.3    Prakash, A.S.4    Mulcahy, R.T.5    Gibson, N.W.6
  • 26
    • 0029073531 scopus 로고
    • Identification of an NAD(P)H: Quinone oxidoreductase polymorphorism and its association with lung cancer and smoking
    • Rosvold EA, McGlynn KA, Lustbader ED, Buetow KH. Identification of an NAD(P)H: quinone oxidoreductase polymorphorism and its association with lung cancer and smoking. Pharmacogenetics. 1995;5:199-206.
    • (1995) Pharmacogenetics , vol.5 , pp. 199-206
    • Rosvold, E.A.1    McGlynn, K.A.2    Lustbader, E.D.3    Buetow, K.H.4
  • 27
    • 0030849791 scopus 로고    scopus 로고
    • Benzene poisoning, a risk factor form hematological malignancy, is associated with the NQO1 609C→T mutation and rapid fractional excretion of chlorzoxazone
    • Rothman N, Smith MT, Hayes RB, et al. Benzene poisoning, a risk factor form hematological malignancy, is associated with the NQO1 609C→T mutation and rapid fractional excretion of chlorzoxazone. Cancer Res. 1997;57:2839-42.
    • (1997) Cancer Res , vol.57 , pp. 2839-2842
    • Rothman, N.1    Smith, M.T.2    Hayes, R.B.3
  • 28
    • 0025248106 scopus 로고
    • Cystolic NAD(P)H:(quinone acceptor) oxidoreductase in human normal and tumor tissue: Effects of cigarette smoking and alcohol
    • Schlager JJ, Powis G. Cystolic NAD(P)H:(quinone acceptor) oxidoreductase in human normal and tumor tissue: effects of cigarette smoking and alcohol. Int J Cancer. 1990;45:403-9.
    • (1990) Int J Cancer , vol.45 , pp. 403-409
    • Schlager, J.J.1    Powis, G.2
  • 29
    • 0020841910 scopus 로고
    • Biochemical and quantitative histochemical study of reduced pyridine nucleotide dehydrogenation by human colonie carcinomas
    • Schor NA, Cornelisse, CJ. Biochemical and quantitative histochemical study of reduced pyridine nucleotide dehydrogenation by human colonie carcinomas. Cancer Res. 1983;43:4850-5.
    • (1983) Cancer Res , vol.43 , pp. 4850-4855
    • Schor, N.A.1    Cornelisse, C.J.2
  • 30
    • 0030857876 scopus 로고    scopus 로고
    • Increased frequency of the null-allele for NAD(P)H:quinone oxidoreductase in patients with urological malignancies
    • Schulz WA, Krumeck A, Rosinger I, et al. Increased frequency of the null-allele for NAD(P)H:quinone oxidoreductase in patients with urological malignancies. Pharmacogenetics. 1997;7:235-9.
    • (1997) Pharmacogenetics , vol.7 , pp. 235-239
    • Schulz, W.A.1    Krumeck, A.2    Rosinger, I.3
  • 31
    • 0035135690 scopus 로고    scopus 로고
    • Rapid polyubiquitination proteasomal degradation of a mutant form of NAD(P)H:quinonone oxidoreductase 1
    • Siegel D, Anwar A, Winski SL, Kepa JK, Dowd KL, Ross D. Rapid polyubiquitination proteasomal degradation of a mutant form of NAD(P)H:quinonone oxidoreductase 1. Mol Pharmacol. 2001;59:263-8.
    • (2001) Mol Pharmacol , vol.59 , pp. 263-268
    • Siegel, D.1    Anwar, A.2    Winski, S.L.3    Kepa, J.K.4    Dowd, K.L.5    Ross, D.6
  • 32
    • 0033534239 scopus 로고    scopus 로고
    • 609 C→T polymorphism in NAD(P)H:quinone oxidoreductase gene in patients with prostatic adenocarcinoma or benign prostatic hyperplasia
    • Steiner M, Hillenbrand M, Borkowsi M, Seiter H, Schuff-Werner P. 609 C→T polymorphism in NAD(P)H:quinone oxidoreductase gene in patients with prostatic adenocarcinoma or benign prostatic hyperplasia. Cancer Lett. 1999;135:67-71.
    • (1999) Cancer Lett , vol.135 , pp. 67-71
    • Steiner, M.1    Hillenbrand, M.2    Borkowsi, M.3    Seiter, H.4    Schuff-Werner, P.5
  • 33
    • 0029906134 scopus 로고    scopus 로고
    • Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H: Quinone oxidoreductase1 gene
    • USA
    • Venugopal R, Jaiswal AK. Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H: quinone oxidoreductase1 gene. Proc Natl Acad Sci USA. 1996;93:14960-5.
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 14960-14965
    • Venugopal, R.1    Jaiswal, A.K.2
  • 34
    • 0028933103 scopus 로고
    • Tobacco and cancer epidemiology and the laboratory
    • Vineis P, Caporaso N. Tobacco and cancer epidemiology and the laboratory. Environ Health Perspect. 1995;103:156-60.
    • (1995) Environ Health Perspect , vol.103 , pp. 156-160
    • Vineis, P.1    Caporaso, N.2
  • 35
    • 0028645493 scopus 로고
    • Enzyme-directed bioreductive drug development revisited. A commentary of recent progress and future prospects with emphasis on quinone anticancer agents and quinone metabolizing enzymes particularly DT-diaphorase
    • Workman P. Enzyme-directed bioreductive drug development revisited. A commentary of recent progress and future prospects with emphasis on quinone anticancer agents and quinone metabolizing enzymes particularly DT-diaphorase. Oncol Res. 1994;6: 461-75.
    • (1994) Oncol Res , vol.6 , pp. 461-475
    • Workman, P.1
  • 36
    • 0030996269 scopus 로고    scopus 로고
    • Involvement of activator protein-1 and nuclear factor-κB transcription factors in the control of the DT-diaphorase expression induced by mitomycin C treatment
    • Yao K-S, Hageboutros A., Ford P, O'Dwyer PJ. Involvement of activator protein-1 and nuclear factor-κB transcription factors in the control of the DT-diaphorase expression induced by mitomycin C treatment. Mol Pharmacol. 1997;51:422-30.
    • (1997) Mol Pharmacol , vol.51 , pp. 422-430
    • Yao, K.-S.1    Hageboutros, A.2    Ford, P.3    O'Dwyer, P.J.4
  • 37


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.