Multiparametric assessment of acute and subacute ischemic neuronal damage: A small animal positron emission tomography study with rat photochemically induced thrombosis model

Synapse

Volumn 65, Issue 3, 2011, Pages 207-214

  Fukumoto, Dai ^a   Hosoya, Teruyo ^a   Nishiyama, Shingo ^a   Harada, Norihiro ^a   Iwata, Hiroshi ^b   Yamamoto, Shigeyuki ^c   Tsukada, Hideo ^a  

^a CENTRAL RESEARCH LABORATORY   (Japan)

^b SHIMADZU CORPORATION   (Japan)

^c HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Benzodiazepine receptors; Inflammation; Ischemic neuronal damage; Rat brain; Small animal PET

Indexed keywords

BENZODIAZEPINE RECEPTOR; FLUMAZENIL C 11; FLUORODEOXYGLUCOSE F 18; LIGAND; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE C 11;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN DAMAGE; BRAIN FUNCTION; BRAIN INFARCTION; BRAIN ISCHEMIA; CELL ACTIVATION; GLUCOSE METABOLISM; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE INJURY; NONHUMAN; PARAMETERS OF MEASUREMENT AND ANALYSIS; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RAT; THROMBOSIS;

EID: 78650641650     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.20836     Document Type: Article

References (41)

1. Abe K, Kashiwagi Y, Tokumura M, Hosoi R, Hatazawa J, Inoue O. 2004. Discrepancy between cell injury and benzodiazepine receptor binding after transient middle cerebral artery occlusion in rats. Synapse 53; 234-239.
2. Banati RB, Newcombe J, Gunn RN, Cagnin A, Turkheimer F, Heppner F, Price G, Wegner F, Giovannoni G, Miller DH, Perkin GD, Smith T, Hewson AK, Bydder G, Kreutzberg GW, Jones T, Cuzner ML, Myers R. 2000. The peripheral benzodiazepine binding site in the brain in multiple sclerosis: Quantitative in vivo imaging of microglia as a measure of disease activity. Brain 123: 2321-2337.
3. 3H]PK 11195, an isoquinoline carboxamide derivative: Kinetic studies and autoradiographic localization. J Neurochem 41: 1744-1750.
4. 3H]DAA1106, a novel and selective ligand for peripheral benzodiazepine receptors. Eur J Pharmacol 371: 197-204.
5. Carayon P, Portier M, Dussossoy D, Bord A, Petitpretre G, Canat X, Le Fur G, Casellas P. 1996. Involvement of peripheral benzodiazepine receptors in the protection of hematopoietic cells against oxygen radical damage. Blood 87: 3170-3178.
6. Chan PH. 1994. Oxygen radicals in focal cerebral ischemia. Brain Pathol 4: 59-65.
7. Chan PH. 1996. Role of oxidants in ischemic brain damage. Stroke 27: 1124-1129.
8. Camsonne R, Crouzel C, Comar D, Maziere M, Prenant C, Sastre J, Moulin MA, Syrota A. 1984. Synthesis of N-["1Cl-methyl-N-(methyl-1propyl)-(chloro-2phenyl)-1 isoquinoline carboxamide-3 (PK11195): A new ligand for peripheral benzodiazepine receptors. J Label Comp Radiopharm 21: 985-991.
9. Fukumoto D, Kawaguchi AT, Haida M, Yamano M, Ogata Y, Tsukada H. 2009. Liposome-encapsulated hemoglobin reduces the size of cerebral infarction in rats: Effect of oxygen affinity. Artif Organs 33: 159-163.
10. 11C]PK11195 and positron emission tomography in patients after ischemic stroke. NeuroReport 11: 2957-2960.
11. 11C](R)-PK11195 PET study. NeuroImage 24: 591-595.
12. Haberkorn U, Bellemann ME, Altmann A, Gerlach L, Morr I, Oberdorfer F, Brix G, Doll J, Blatter J, van Kaick G. 1997. PET 2-fluoro-2-deoxyglucose uptake in rat prostate adenocarcinoma during chemotherapy with gemcitabine. J Nucl Med 38: 1215-1221.
13. 2O positron emission tomography predicts irreversible ischemic cortical damage in stroke patients receiving acute thrombolytic therapy. Stroke 31: 366-369.
14. Inoue O, Yanamoto K, Fujiwara Y, Hosoi R, Kobayashi K, Tsukada H. 2003. Sensitivities of benzodiazepine receptor binding and muscarinic acetylcholine receptor binding for the detection of neural cell death caused by sodium nitroprusside microinjection in rat brain. Synapse 49: 134-141.
15. Itzhak Y, Baker L, Norenberg MD. 1983. Characterization of the peripheral-type benzodiazepine receptors in cultured astrocytes: Evidence for multiplicity. Glia 9: 211-218.
16. Kawaguchi A, Fukumoto D, Haida M, Ogata Y, Yamano M, Tsukada H. 2007. Liposome-encapsulated hemoglobin reduced the size of cerebral infarction in the rat: Evaluation with photochemically induced thrombosis of the middle cerebral artery. Stroke 38: 1626-1632.
17. Kubota R, Yamada S, Kubota K, Ishiwata K, Tamahashi N, Ido T. 1992. Intratumoral distribution of fluorine-18-fluorodeoxyglucose in vivo: High accumulation in macrophages and granulation tissues studied by microautoradiography. J Nucl Med 33: 1972-1980.
18. Maziere M, Hantraye P, Prenant C, Sastre J, Comar D. 1984. Rol5-1788, a specific radioligand for 'in vivo' central benzodiazepine receptor study by positron emission tomography. Appl Radiat Isotop 35: 973-976.
19. Mizuta T, Kitamura K, Iwata H, Yamagishi Y, Ohtani A, Tanaka K, Inoue Y. 2008. Performance evaluation of a high-sensitivity large-aperture small-animal PET scanner: ClairvivoPET. Ann Nucl Med 22: 447-455.
20. 18F]FLT for monitoring the tumor response to radiotherapy in mice. J Nucl Med 50: 290-295.
21. 3H-PK11195 binding in rat cerebral cortex following a local ischemic lesion. J Cereb Blood Flow Metab 11: 314-322.
22. 19F-NMR spectroscopy. Int J Appl Radiat Isot 37: 695-700.
23. 11C]PK11195. Neurology 55: 1052-1054.
24. Park CH, Carboni E, Wood PL, Gee KW. 1996. Characterization of peripheral benzodiazepine type sites in a cultured murine BV-2 microglial cell line. Glia 16: 65-70.
25. Price CJ, Wang D, Menon DK, Guadagno JV, Cleij M, Fryer T, Aigbirhio F, Baron JC, Warburton EA. 2006. Intrinsic activated microglia map to the peri-infarct zone in the subacute phase of ischemic stroke. Stroke 37: 1749-1753.
26. Ramsay SC, Weiller C, Myers R, Cremer JE, Luthra SK, Lammertsma AA, Frackowiak RS. 1992. Monitoring by PET of macrophage accumulation in brain after ischemic stroke. Lancet 339: 1054-1055.
27. 11C]PK11195 by PET and induction of the peripheral-type benzodiazepine receptor after transient focal ischemia in rats. J Cereb Blood Flow Metab 27: 1075-1986.
28. Schaider H, Haberkorn U, Berger MR, Oberdorfer F, Morr I, van Kaick G. 1996. Application of α-aminoisobutyric acid. L-methionine, thymidine and 2-fluoro-2-deoxy-D-glucose to monitor effects of chemotherapy in a human colon carcinoma cell line. Eur J Nucl Med 23: 55-60.
29. 18F]FDG-PET study. J Cereb Blood Flow Metab 29: 1216-1225.
30. Sette G, Baron J-C, Young AR, Miyazawa H, Tillet I, Barrd L, Travere J-M, Derlon J-M, MacKenzie ET. 1993. In vivo mapping of brain benzodiazepine receptor changes by positron emission tomography after focal ischemia in the anesthetized baboon. Stroke 24: 2046-2058.
31. 18F-fluorothymidine for monitoring tumor response to radiotherapy and photodynamic therapy in mice. J Nucl Med 45: 1754-1758.
32. Takamatsu H, Kondo K, Ikeda Y, Umemura K. 1998. Neuroprotective effects depend on the model of focal ischemia following middle cerebral artery occlusion. Eur J Pharmacol 362: 137-142.
33. Takamatsu H, Tsukada H, Kakiuchi T, Tatsumi M, Umemura K. 2000. Changes in local cerebral blood flow in photochemically induced thrombotic occlusion model in rats. Eur J Pharmacol 398: 375-379.
34. Takamatsu H, Tsukada H, Watanabe Y, Cui Y, Kataoka Y, Hosoya T, Suzuki M, Watanabe Y. 2002. Specific ligand for a central type prostacycline receptor attenuates damage in a rat model of focal cerebral ischemia. Brain Res 925: 176-182.
35. Umemura K, Wada K, Uematsu T, Nakashima M. 1993. Evaluation of the combination of a tissue-type plasminogen activator. SUN9216, and a thromboxane A2 receptor antagonist, vapiprost, in a rat middle cerebral artery thrombosis model. Stroke 24: 1077-1082.
36. Umemura K, Gemba T, Mizuno A, Nakashima M. 1996. Inhibitory effect of MS-153 on elevated brain glutamate level induced by the rat middle cerebral artery occlusion. Stroke 27: 1624-1628.
37. Wake H, Moorhouse AJ, Jinno S, Kohsaka S, Nabekura J. 2009. Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals. J Neurosci 29: 3974-3980.
38. Yamada S, Kubota K, Kubota R, Ido T, Tamahashi N. 1995. High accumulation of fluorine-18-fluorodeoxyglucose in turpentine-induced inflammatory tissue. J Nucl Med 36: 1301-1306.
39. Yang G-Y, Betz AL. 1994. Reperfusion-induced injury to the blood-brain barrier after middle cerebral artery occlusion in rats. Stroke 25: 1658-1665.
40. 11C]DAA1106: Radiosynthesis and in vivo binding to peripheral benzodiazepine receptors in mouse brain. Nucl Med Biol 30: 513-519.
41. Zhao L, Yamashima T, Wang XD, Tonchev A, Yamashita J, Kakiuchi T, Nishiyama, Kuhara S, Takahashi K, Tsukada H. 2002. PET imaging of ischemic neuronal death in the hippocampus of living monkey. Hippocampus 12: 309-318.