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Volumn 185, Issue 12, 2010, Pages 7443-7451

Human eosinophils exert TNF-α and granzyme a-mediated tumoricidal activity toward colon carcinoma cells

Author keywords

[No Author keywords available]

Indexed keywords

CD18 ANTIGEN; EOSINOPHIL CATIONIC PROTEIN; GRANZYME A; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MONOCLONAL ANTIBODY; NAFAMSTAT MESILATE; NEUROTOXIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 78650632745     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1000446     Document Type: Article
Times cited : (136)

References (52)
  • 2
    • 34249780819 scopus 로고    scopus 로고
    • Eosinophils: Singularly destructive effector cells or purveyors of immunoregulation?
    • Jacobsen, E. A., A. G. Taranova, N. A. Lee, and J. J. Lee. 2007. Eosinophils: singularly destructive effector cells or purveyors of immunoregulation? J. Allergy Clin. Immunol. 119:1313-1320.
    • (2007) J. Allergy Clin. Immunol. , vol.119 , pp. 1313-1320
    • Jacobsen, E.A.1    Taranova, A.G.2    Lee, N.A.3    Lee, J.J.4
  • 3
    • 1542405217 scopus 로고    scopus 로고
    • Eosinophils: 'new' roles for 'old' cells
    • Munitz, A., and F. Levi-Schaffer. 2004. Eosinophils: 'new' roles for 'old' cells. Allergy 59:268-275.
    • (2004) Allergy , vol.59 , pp. 268-275
    • Munitz, A.1    Levi-Schaffer, F.2
  • 4
    • 33845966763 scopus 로고    scopus 로고
    • Eosinophilic granulocytes and damage-associated molecular pattern molecules (DAMPs): Role in the inflammatory response within tumors
    • Lotfi, R., J. J. Lee, and M. T. Lotze. 2007. Eosinophilic granulocytes and damage-associated molecular pattern molecules (DAMPs): role in the inflammatory response within tumors. J. Immunother. 30:16-28.
    • (2007) J. Immunother. , vol.30 , pp. 16-28
    • Lotfi, R.1    Lee, J.J.2    Lotze, M.T.3
  • 5
    • 0019766379 scopus 로고
    • Tumour-associated eosinophilia: A review
    • Lowe, D., J. Jorizzo, and M. S. Hutt. 1981. Tumour-associated eosinophilia: a review. J. Clin. Pathol. 34:1343-1348.
    • (1981) J. Clin. Pathol. , vol.34 , pp. 1343-1348
    • Lowe, D.1    Jorizzo, J.2    Hutt, M.S.3
  • 6
    • 23844440914 scopus 로고    scopus 로고
    • Allergy and cancer: A biological and epidemiological rebus
    • Carrozzi, L., and G. Viegi. 2005. Allergy and cancer: a biological and epidemiological rebus. Allergy 60:1095-1097.
    • (2005) Allergy , vol.60 , pp. 1095-1097
    • Carrozzi, L.1    Viegi, G.2
  • 7
    • 0036372954 scopus 로고    scopus 로고
    • Tumour-associated tissue eosinophilia as a prognostic factor in oral squamous cell carcinomas
    • Dorta, R. G., G. Landman, L. P. Kowalski, J. R. Lauris, M. R. Latorre, and D. T. Oliveira. 2002. Tumour-associated tissue eosinophilia as a prognostic factor in oral squamous cell carcinomas. Histopathology 41:152-157.
    • (2002) Histopathology , vol.41 , pp. 152-157
    • Dorta, R.G.1    Landman, G.2    Kowalski, L.P.3    Lauris, J.R.4    Latorre, M.R.5    Oliveira, D.T.6
  • 8
    • 0036126071 scopus 로고    scopus 로고
    • Significance of epidermal growth factor receptor and tumor associated tissue eosinophilia in the prognosis of patients with nasopharyngeal carcinoma
    • Fujii, M., T. Yamashita, R. Ishiguro, M. Tashiro, and K. Kameyama. 2002. Significance of epidermal growth factor receptor and tumor associated tissue eosinophilia in the prognosis of patients with nasopharyngeal carcinoma. Auris Nasus Larynx 29:175-181.
    • (2002) Auris Nasus Larynx , vol.29 , pp. 175-181
    • Fujii, M.1    Yamashita, T.2    Ishiguro, R.3    Tashiro, M.4    Kameyama, K.5
  • 10
    • 0032716777 scopus 로고    scopus 로고
    • Independent prognostic value of eosinophil and mast cell infiltration in colorectal cancer tissue
    • Nielsen, H. J., U. Hansen, I. J. Christensen, C. M. Reimert, N. Brünner, and F. Moesgaard. 1999. Independent prognostic value of eosinophil and mast cell infiltration in colorectal cancer tissue. J. Pathol. 189:487-495.
    • (1999) J. Pathol. , vol.189 , pp. 487-495
    • Nielsen, H.J.1    Hansen, U.2    Christensen, I.J.3    Reimert, C.M.4    Brünner, N.5    Moesgaard, F.6
  • 11
    • 0342424368 scopus 로고    scopus 로고
    • Prognostic influence of tumor-associated eosinophilic infiltrate in colorectal carcinoma
    • Fernández-Aceñero, M. J., M. Galindo-Gallego, J. Sanz, and A. Aljama. 2000. Prognostic influence of tumor-associated eosinophilic infiltrate in colorectal carcinoma. Cancer 88:1544-1548.
    • (2000) Cancer , vol.88 , pp. 1544-1548
    • Fernández-Aceñero, M.J.1    Galindo-Gallego, M.2    Sanz, J.3    Aljama, A.4
  • 13
    • 0037415596 scopus 로고    scopus 로고
    • Immunotherapy of cytotoxic T cell-resistant tumors by T helper 2 cells: An eotaxin and STAT6-dependent process
    • Mattes, J., M. Hulett, W. Xie, S. Hogan, M. E. Rothenberg, P. Foster, and C. Parish. 2003. Immunotherapy of cytotoxic T cell-resistant tumors by T helper 2 cells: an eotaxin and STAT6-dependent process. J. Exp. Med. 197:387-393.
    • (2003) J. Exp. Med. , vol.197 , pp. 387-393
    • Mattes, J.1    Hulett, M.2    Xie, W.3    Hogan, S.4    Rothenberg, M.E.5    Foster, P.6    Parish, C.7
  • 15
    • 37249016685 scopus 로고    scopus 로고
    • Eosinophils
    • John Wiley & Sons, New York. Available at
    • Wagner, L., K. M. Leiferman, and G. J. Gleich. 2006. Eosinophils. In: Encyclopedia of Life Sciences. John Wiley & Sons, New York. Available at: http://onlinelibrary.wiley.com/doi/10.1002/9780470015902.a0001126/full.
    • (2006) Encyclopedia of Life Sciences
    • Wagner, L.1    Leiferman, K.M.2    Gleich, G.J.3
  • 16
    • 58149271090 scopus 로고    scopus 로고
    • Human eosinophils constitutively express multiple Th1, Th2, and immunoregulatory cytokines that are secreted rapidly and differentially
    • Spencer, L. A., C. T. Szela, S. A. Perez, C. L. Kirchhoffer, J. S. Neves, A. L. Radke, and P. F. Weller. 2009. Human eosinophils constitutively express multiple Th1, Th2, and immunoregulatory cytokines that are secreted rapidly and differentially. J. Leukoc. Biol. 85:117-123.
    • (2009) J. Leukoc. Biol. , vol.85 , pp. 117-123
    • Spencer, L.A.1    Szela, C.T.2    Perez, S.A.3    Kirchhoffer, C.L.4    Neves, J.S.5    Radke, A.L.6    Weller, P.F.7
  • 17
    • 0033575793 scopus 로고    scopus 로고
    • Expression of CD28 and CD86 by human eosinophils and role in the secretion of type 1 cytokines (interleukin 2 and interferon gamma): Inhibition by immunoglobulin a complexes
    • Woerly, G., N. Roger, S. Loiseau, D. Dombrowicz, A. Capron, and M. Capron. 1999. Expression of CD28 and CD86 by human eosinophils and role in the secretion of type 1 cytokines (interleukin 2 and interferon gamma): inhibition by immunoglobulin a complexes. J. Exp. Med. 190:487-495.
    • (1999) J. Exp. Med. , vol.190 , pp. 487-495
    • Woerly, G.1    Roger, N.2    Loiseau, S.3    Dombrowicz, D.4    Capron, A.5    Capron, M.6
  • 19
    • 33847676918 scopus 로고    scopus 로고
    • Mast cell and eosinophil interaction in gastric carcinomas: Ultrastructural observations
    • Caruso, R. A., F. Fedele, V. Zuccalá, M. G. Fracassi, and A. Venuti. 2007. Mast cell and eosinophil interaction in gastric carcinomas: ultrastructural observations. Anticancer Res. 27 (1 A): 391-394.
    • (2007) Anticancer Res. , vol.27 , Issue.1 A , pp. 391-394
    • Caruso, R.A.1    Fedele, F.2    Zuccalá, V.3    Fracassi, M.G.4    Venuti, A.5
  • 23
    • 34247593032 scopus 로고    scopus 로고
    • Human gammadelta Tlymphocytes strip and kill tumor cells simultaneously
    • Gertner, J., A. Wiedemann, M. Poupot, and J. J. Fournié. 2007. Human gammadelta Tlymphocytes strip and kill tumor cells simultaneously. Immunol. Lett. 110:42-53.
    • (2007) Immunol. Lett. , vol.110 , pp. 42-53
    • Gertner, J.1    Wiedemann, A.2    Poupot, M.3    Fournié, J.J.4
  • 24
    • 67649213021 scopus 로고    scopus 로고
    • Reduced expression of the mevalonate pathway enzyme farnesyl pyrophosphate synthase unveils recognition of tumor cells by Vgamma9Vdelta2 T cells
    • Li, J., M. J. Herold, B. Kimmel, I. Müller, B. Rincon-Orozco, V. Kunzmann, and T. Herrmann. 2009. Reduced expression of the mevalonate pathway enzyme farnesyl pyrophosphate synthase unveils recognition of tumor cells by Vgamma9Vdelta2 T cells. J. Immunol. 182:8118-8124.
    • (2009) J. Immunol. , vol.182 , pp. 8118-8124
    • Li, J.1    Herold, M.J.2    Kimmel, B.3    Müller, I.4    Rincon-Orozco, B.5    Kunzmann, V.6    Herrmann, T.7
  • 25
    • 0035282856 scopus 로고    scopus 로고
    • A novel technique for the fluorometric assessment of T lymphocyte antigen specific lysis
    • Sheehy, M. E., A. B. McDermott, S. N. Furlan, P. Klenerman, and D. F. Nixon. 2001. A novel technique for the fluorometric assessment of T lymphocyte antigen specific lysis. J. Immunol. Methods 249:99-110.
    • (2001) J. Immunol. Methods , vol.249 , pp. 99-110
    • Sheehy, M.E.1    McDermott, A.B.2    Furlan, S.N.3    Klenerman, P.4    Nixon, D.F.5
  • 26
    • 17444392214 scopus 로고    scopus 로고
    • Human NK cells lyse organ-specific endothelial cells: Analysis of adhesion and cytotoxic mechanisms
    • Bielawska-Pohl, A., C. Crola, A. Caignard, C. Gaudin, D. Dus, C. Kieda, and S. Chouaib. 2005. Human NK cells lyse organ-specific endothelial cells: analysis of adhesion and cytotoxic mechanisms. J. Immunol. 174:5573-5582.
    • (2005) J. Immunol. , vol.174 , pp. 5573-5582
    • Bielawska-Pohl, A.1    Crola, C.2    Caignard, A.3    Gaudin, C.4    Dus, D.5    Kieda, C.6    Chouaib, S.7
  • 27
    • 0032529628 scopus 로고    scopus 로고
    • Protein kinase C is involved in the regulation of both signaling and adhesion mediated by DNAX accessory molecule-1 receptor
    • Shibuya, A., L. L. Lanier, and J. H. Phillips. 1998. Protein kinase C is involved in the regulation of both signaling and adhesion mediated by DNAX accessory molecule-1 receptor. J. Immunol. 161:1671-1676. (Pubitemid 28387583)
    • (1998) Journal of Immunology , vol.161 , Issue.4 , pp. 1671-1676
    • Shibuya, A.1    Lanier, L.L.2    Phillips, J.H.3
  • 30
    • 42949098879 scopus 로고    scopus 로고
    • Death by a thousand cuts: Granzyme pathways of programmed cell death
    • Chowdhury, D., and J. Lieberman. 2008. Death by a thousand cuts: granzyme pathways of programmed cell death. Annu. Rev. Immunol. 26:389-420.
    • (2008) Annu. Rev. Immunol. , vol.26 , pp. 389-420
    • Chowdhury, D.1    Lieberman, J.2
  • 31
    • 0026078467 scopus 로고
    • The enzymatic activity of human cytotoxic T-lymphocyte granzyme A and cytolysis mediated by cytotoxic T-lymphocytes are potently inhibited by a synthetic antiprotease, FUT-175
    • Poe, M., J. K. Wu, J. T. Blake, H. J. Zweerink, and N. H. Sigal. 1991. The enzymatic activity of human cytotoxic T-lymphocyte granzyme A and cytolysis mediated by cytotoxic T-lymphocytes are potently inhibited by a synthetic antiprotease, FUT-175. Arch. Biochem. Biophys. 284:215-218.
    • (1991) Arch. Biochem. Biophys. , vol.284 , pp. 215-218
    • Poe, M.1    Wu, J.K.2    Blake, J.T.3    Zweerink, H.J.4    Sigal, N.H.5
  • 32
    • 0032983328 scopus 로고    scopus 로고
    • Selectin and Lewis (x) are required as co-receptors in antibodydependent cell-mediated cytotoxicity of human eosinophils to Schistosoma mansoni schistosomula
    • Nutten, S., J. P. Papin, G. Woerly, D. W. Dunne, J. MacGregor, F. Trottein, and M. Capron. 1999. Selectin and Lewis (x) are required as co-receptors in antibodydependent cell-mediated cytotoxicity of human eosinophils to Schistosoma mansoni schistosomula. Eur. J. Immunol. 29:799-808.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 799-808
    • Nutten, S.1    Papin, J.P.2    Woerly, G.3    Dunne, D.W.4    MacGregor, J.5    Trottein, F.6    Capron, M.7
  • 33
    • 33745852256 scopus 로고    scopus 로고
    • Involvement of CD166 in the activation of human gamma delta T cells by tumor cells sensitized with nonpeptide antigens
    • Kato, Y., Y. Tanaka, M. Hayashi, K. Okawa, and N. Minato. 2006. Involvement of CD166 in the activation of human gamma delta T cells by tumor cells sensitized with nonpeptide antigens. J. Immunol. 177:877-884.
    • (2006) J. Immunol. , vol.177 , pp. 877-884
    • Kato, Y.1    Tanaka, Y.2    Hayashi, M.3    Okawa, K.4    Minato, N.5
  • 35
    • 0031728860 scopus 로고    scopus 로고
    • LFA-1 expression by blood eosinophils is increased in atopic asthmatic children and is involved in eosinophil locomotion
    • Lantero, S., G. Alessandri, D. Spallarossa, L. Scarso, and G. A. Rossi. 1998. LFA-1 expression by blood eosinophils is increased in atopic asthmatic children and is involved in eosinophil locomotion. Eur. Respir. J. 12:1094-1098.
    • (1998) Eur. Respir. J , vol.12 , pp. 1094-1098
    • Lantero, S.1    Alessandri, G.2    Spallarossa, D.3    Scarso, L.4    Rossi, G.A.5
  • 37
    • 0038364073 scopus 로고    scopus 로고
    • Macrophages from cancer patients: Analysis of TRAIL, TRAIL receptors, and colon tumor cell apoptosis
    • Herbeuval, J. P., C. Lambert, O. Sabido, M. Cottier, P. Fournel, M. Dy, and C. Genin. 2003. Macrophages from cancer patients: analysis of TRAIL, TRAIL receptors, and colon tumor cell apoptosis. J. Natl. Cancer Inst. 95:611-621.
    • (2003) J. Natl. Cancer Inst. , vol.95 , pp. 611-621
    • Herbeuval, J.P.1    Lambert, C.2    Sabido, O.3    Cottier, M.4    Fournel, P.5    Dy, M.6    Genin, C.7
  • 38
    • 0036779576 scopus 로고    scopus 로고
    • Functional significance of the perforin/granzyme cell death pathway
    • Trapani, J. A., and M. J. Smyth. 2002. Functional significance of the perforin/granzyme cell death pathway. Nat. Rev. Immunol. 2:735-747.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 735-747
    • Trapani, J.A.1    Smyth, M.J.2
  • 39
    • 1642459276 scopus 로고    scopus 로고
    • Granzyme A: An additional weapon of human polymorphonuclear neutrophils (PMNs) in innate immunity?
    • Hochegger, K., P. Eller, and A. R. Rosenkranz. 2004. Granzyme A: an additional weapon of human polymorphonuclear neutrophils (PMNs) in innate immunity? Blood 103:1176.
    • (2004) Blood , vol.103 , pp. 1176
    • Hochegger, K.1    Eller, P.2    Rosenkranz, A.R.3
  • 41
    • 58249095956 scopus 로고    scopus 로고
    • The membrane repair response masks membrane disturbances caused by cellpenetrating peptide uptake
    • Palm-Apergi, C., A. Lorents, K. Padari, M. Pooga, and M. Hallbrink. 2009. The membrane repair response masks membrane disturbances caused by cellpenetrating peptide uptake. FASEB J. 23:214-223.
    • (2009) FASEB J , vol.23 , pp. 214-223
    • Palm-Apergi, C.1    Lorents, A.2    Padari, K.3    Pooga, M.4    Hallbrink, M.5
  • 42
    • 52649093457 scopus 로고    scopus 로고
    • Granzyme A causes detachment of alveolar epithelial A549 cells accompanied by promotion of interleukin-8 release
    • Yoshikawa, Y., H. Hirayasu, S. Tsuzuki, and T. Fushiki. 2008. Granzyme A causes detachment of alveolar epithelial A549 cells accompanied by promotion of interleukin-8 release. Biosci. Biotechnol. Biochem. 72:2481-2484.
    • (2008) Biosci. Biotechnol. Biochem. , vol.72 , pp. 2481-2484
    • Yoshikawa, Y.1    Hirayasu, H.2    Tsuzuki, S.3    Fushiki, T.4
  • 43
    • 52649099075 scopus 로고    scopus 로고
    • A lymphocyte serine protease granzyme A causes detachment of a small-intestinal epithelial cell line (IEC-6)
    • Hirayasu, H., Y. Yoshikawa, S. Tsuzuki, and T. Fushiki. 2008. A lymphocyte serine protease granzyme A causes detachment of a small-intestinal epithelial cell line (IEC-6). Biosci. Biotechnol. Biochem. 72:2294-2302.
    • (2008) Biosci. Biotechnol. Biochem. , vol.72 , pp. 2294-2302
    • Hirayasu, H.1    Yoshikawa, Y.2    Tsuzuki, S.3    Fushiki, T.4
  • 44
    • 33846533653 scopus 로고    scopus 로고
    • A role of a lymphocyte tryptase, granzyme A, in experimental ulcerative colitis
    • Hirayasu, H., Y. Yoshikawa, S. Tsuzuki, and T. Fushiki. 2007. A role of a lymphocyte tryptase, granzyme A, in experimental ulcerative colitis. Biosci. Biotechnol. Biochem. 71:234-237.
    • (2007) Biosci. Biotechnol. Biochem. , vol.71 , pp. 234-237
    • Hirayasu, H.1    Yoshikawa, Y.2    Tsuzuki, S.3    Fushiki, T.4
  • 45
    • 58149260267 scopus 로고    scopus 로고
    • The cytolytic enzymes granyzme A, granzyme B, and perforin: Expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression
    • Chattopadhyay, P. K., M. R. Betts, D. A. Price, E. Gostick, H. Horton, M. Roederer, and S. C. De Rosa. 2009. The cytolytic enzymes granyzme A, granzyme B, and perforin: expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression. J. Leukoc. Biol. 85:88-97.
    • (2009) J. Leukoc. Biol. , vol.85 , pp. 88-97
    • Chattopadhyay, P.K.1    Betts, M.R.2    Price, D.A.3    Gostick, E.4    Horton, H.5    Roederer, M.6    De Rosa, S.C.7
  • 46
    • 0032477288 scopus 로고    scopus 로고
    • Unique recombinant human ribonuclease and inhibition of Kaposi's sarcoma cell growth
    • Newton, D. L., and S. M. Rybak. 1998. Unique recombinant human ribonuclease and inhibition of Kaposi's sarcoma cell growth. J. Natl. Cancer Inst. 90:1787-1791.
    • (1998) J. Natl. Cancer Inst. , vol.90 , pp. 1787-1791
    • Newton, D.L.1    Rybak, S.M.2
  • 48
    • 0036296163 scopus 로고    scopus 로고
    • Crystallographic and functional studies of a modified form of eosinophil-derived neurotoxin (EDN) with novel biological activities
    • Chang, C., D. L. Newton, S. M. Rybak, and A. Wlodawer. 2002. Crystallographic and functional studies of a modified form of eosinophil-derived neurotoxin (EDN) with novel biological activities. J. Mol. Biol. 317:119-130.
    • (2002) J. Mol. Biol. , vol.317 , pp. 119-130
    • Chang, C.1    Newton, D.L.2    Rybak, S.M.3    Wlodawer, A.4
  • 49
    • 20944447573 scopus 로고    scopus 로고
    • Surface-exposed amino acids of eosinophil cationic protein play a critical role in the inhibition of mammalian cell proliferation
    • Carreras, E., E. Boix, S. Navarro, H. F. Rosenberg, C. M. Cuchillo, and M. V. Nogués. 2005. Surface-exposed amino acids of eosinophil cationic protein play a critical role in the inhibition of mammalian cell proliferation. Mol. Cell. Biochem. 272:1-7.
    • (2005) Mol. Cell. Biochem. , vol.272 , pp. 1-7
    • Carreras, E.1    Boix, E.2    Navarro, S.3    Rosenberg, H.F.4    Cuchillo, C.M.5    Nogués, M.V.6
  • 50
    • 0022558797 scopus 로고
    • Mechanism of membrane damage mediated by human eosinophil cationic protein
    • Young, J. D., C. G. Peterson, P. Venge, and Z. A. Cohn. 1986. Mechanism of membrane damage mediated by human eosinophil cationic protein. Nature 321:613-616.
    • (1986) Nature , vol.321 , pp. 613-616
    • Young, J.D.1    Peterson, C.G.2    Venge, P.3    Cohn, Z.A.4
  • 52
    • 38549179303 scopus 로고    scopus 로고
    • The cytotoxicity of eosinophil cationic protein/ribonuclease 3 on eukaryotic cell lines takes place through its aggregation on the cell membrane
    • Navarro, S., J. Aleu, M. Jiménez, E. Boix, C. M. Cuchillo, and M. V. Nogués. 2008. The cytotoxicity of eosinophil cationic protein/ribonuclease 3 on eukaryotic cell lines takes place through its aggregation on the cell membrane. Cell. Mol. Life Sci. 65:324-337.
    • (2008) Cell. Mol. Life Sci. , vol.65 , pp. 324-337
    • Navarro, S.1    Aleu, J.2    Jiménez, M.3    Boix, E.4    Cuchillo, C.M.5    Nogués, M.V.6


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