BMP antagonists enhance myogenic differentiation and ameliorate the dystrophic phenotype in a DMD mouse model

Neurobiology of Disease

Volumn 41, Issue 2, 2011, Pages 353-360

  Shi, SongTing ^a   Hoogaars, Willem M H ^b   de Gorter, David J J ^a   van Heiningen, Sandra H ^a,b   Lin, Herbert Y ^c   Hong, Charles C ^d   Kemaladewi, Dwi U ^b   Aartsma Rus, Annemieke ^b   ten Dijke, Peter ^a   't Hoen, Peter A C ^b  

^a Centre for Biomedical Genetics   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BMP signaling; DMD; Myogenic differentiation

Indexed keywords

ADENOVIRUS VECTOR; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 4; DORSOMORPHIN; LDN 193189; MYOD1 PROTEIN; MYOGENIC FACTOR; NOGGIN; PROTEIN INHIBITOR; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; DUCHENNE MUSCULAR DYSTROPHY; GENE OVEREXPRESSION; GENE REPRESSION; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; MUSCLE DEVELOPMENT; MUSCLE REGENERATION; MYOBLAST; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SERIAL ANALYSIS OF GENE EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; BONE MORPHOGENETIC PROTEINS; CARRIER PROTEINS; CELL DIFFERENTIATION; CELL LINE; DISEASE MODELS, ANIMAL; HUMANS; MALE; MICE; MICE, INBRED MDX; MICE, KNOCKOUT; MUSCLE, SKELETAL; MUSCULAR DYSTROPHY, DUCHENNE; MYOBLASTS; PHENOTYPE;

EID: 78650601288     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2010.10.003     Document Type: Article

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