Intraflagellar Transport Protein 27 Is a Small G Protein Involved in Cell-Cycle Control

Current Biology

Volumn 17, Issue 3, 2007, Pages 193-202

  Qin, Hongmin ^a   Wang, Zhaohui ^a   Diener, Dennis ^a   Rosenbaum, Joel ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

CELLBIO

Indexed keywords

ALGAL PROTEIN; CELL CYCLE PROTEIN; GREEN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL; ARTICLE; CELL CYCLE; CHEMISTRY; CHLAMYDOMONAS REINHARDTII; CYTOLOGY; FLAGELLUM; GENETICS; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL;

ALGAL PROTEINS; ANIMALS; BIOLOGICAL TRANSPORT; CELL CYCLE; CELL CYCLE PROTEINS; CHLAMYDOMONAS REINHARDTII; FLAGELLA; GREEN FLUORESCENT PROTEINS; GTP-BINDING PROTEINS;

EUKARYOTA;

EID: 33846605643     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2006.12.040     Document Type: Article

References (47)

1. Dutcher S.K. Elucidation of basal body and centriole functions in Chlamydomonas reinhardtii. Traffic 4 (2003) 443-451
2. Kozminski K.G., Johnson K.A., Forscher P., and Rosenbaum J.L. A motility in the eukaryotic flagellum unrelated to flagellar beating. Proc. Natl. Acad. Sci. USA 90 (1993) 5519-5523
3. Qin H., Diener D.R., Geimer S., Cole D.G., and Rosenbaum J.L. Intraflagellar transport (IFT) cargo: IFT transports flagellar precursors to the tip and turnover products to the cell body. J. Cell Biol. 164 (2004) 255-266
4. Cole D.G., Diener D.R., Himelblau A.L., Beech P.L., Fuster J.C., and Rosenbaum J.L. Chlamydomonas kinesin-II-dependent intraflagellar transport (IFT): IFT particles contain proteins required for ciliary assembly in Caenorhabditis elegans sensory neurons. J. Cell Biol. 141 (1998) 993-1008
5. Scholey J.M. Intraflagellar transport. Annu. Rev. Cell Dev. Biol. 19 (2003) 423-443
6. Rosenbaum J.L., and Witman G.B. Intraflagellar transport. Nat. Rev. Mol. Cell Biol. 3 (2002) 813-825
7. Pazour G.J., Dickert B.L., and Witman G.B. The DHC1b (DHC2) isoform of cytoplasmic dynein is required for flagellar assembly. J. Cell Biol. 144 (1999) 473-481
8. Pazour G.J., Dickert B.L., Vucica Y., Seeley E.S., Rosenbaum J.L., Witman G.B., and Cole D.G. Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella. J. Cell Biol. 151 (2000) 709-718
9. Porter M.E., Bower R., Knott J.A., Byrd P., and Dentler W. Cytoplasmic dynein heavy chain 1b is required for flagellar assembly in Chlamydomonas. Mol. Biol. Cell 10 (1999) 693-712
10. Brazelton W.J., Amundsen C.D., Silflow C.D., and Lefebvre P.A. The bld1 mutation identifies the Chlamydomonas osm-6 homolog as a gene required for flagellar assembly. Curr. Biol. 11 (2001) 1591-1594
11. Cole D.G. The intraflagellar transport machinery of Chlamydomonas reinhardtii. Traffic 4 (2003) 435-442
12. Bradley B.A., and Quarmby L.M. A NIMA-related kinase, Cnk2p, regulates both flagellar length and cell size in Chlamydomonas. J. Cell Sci. 118 (2005) 3317-3326
13. Mahjoub M.R., Montpetit B., Zhao L., Finst R.J., Goh B., Kim A.C., and Quarmby L.M. The FA2 gene of Chlamydomonas encodes a NIMA family kinase with roles in cell cycle progression and microtubule severing during deflagellation. J. Cell Sci. 115 (2002) 1759-1768
14. Wennerberg K., Rossman K.L., and Der C.J. The Ras superfamily at a glance. J. Cell Sci. 118 (2005) 843-846
15. Bourne H.R., Sanders D.A., and McCormick F. The GTPase superfamily: Conserved structure and molecular mechanism. Nature 349 (1991) 117-127
16. Dentler W. Intraflagellar transport (IFT) during assembly and disassembly of Chlamydomonas flagella. J. Cell Biol. 170 (2005) 649-659
17. Hou Y., Pazour G.J., and Witman G.B. A dynein light intermediate chain, D1bLIC, is required for retrograde intraflagellar transport. Mol. Biol. Cell 15 (2004) 4382-4394
18. Rohr J., Sarkar N., Balenger S., Jeong B.R., and Cerutti H. Tandem inverted repeat system for selection of effective transgenic RNAi strains in Chlamydomonas. Plant J. 40 (2004) 611-621
19. Lucker B.F., Behal R.H., Qin H., Siron L.C., Taggart W.D., Rosenbaum J.L., and Cole D.G. Characterization of the intraflagellar transport complex B core: Direct interaction of the IFT81 and IFT74/72 subunits. J. Biol. Chem. 280 (2005) 27688-27696
20. Kouranti I., Sachse M., Arouche N., Goud B., and Echard A. Rab35 regulates an endocytic recycling pathway essential for the terminal steps of cytokinesis. Curr. Biol. 16 (2006) 1719-1725
21. Gromley A., Jurczyk A., Sillibourne J., Halilovic E., Mogensen M., Groisman I., Blomberg M., and Doxsey S. A novel human protein of the maternal centriole is required for the final stages of cytokinesis and entry into S phase. J. Cell Biol. 161 (2003) 535-545
22. Gromley A., Yeaman C., Rosa J., Redick S., Chen C.T., Mirabelle S., Guha M., Sillibourne J., and Doxsey S.J. Centriolin anchoring of exocyst and SNARE complexes at the midbody is required for secretory-vesicle-mediated abscission. Cell 123 (2005) 75-87
23. Qin H., Burnette D.T., Bae Y.K., Forscher P., Barr M.M., and Rosenbaum J.L. Intraflagellar transport is required for the vectorial movement of TRPV channels in the ciliary membrane. Curr. Biol. 15 (2005) 1695-1699
24. Singla V., and Reiter J.F. The primary cilium as the cell's antenna: Signaling at a sensory organelle. Science 313 (2006) 629-633
25. Praetorius H.A., and Spring K.R. Bending the MDCK cell primary cilium increases intracellular calcium. J. Membr. Biol. 184 (2001) 71-79
26. Nauli S.M., Alenghat F.J., Luo Y., Williams E., Vassilev P., Li X., Elia A.E., Lu W., Brown E.M., Quinn S.J., et al. Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat. Genet. 33 (2003) 129-137
27. Igarashi P., and Somlo S. Genetics and pathogenesis of polycystic kidney disease. J. Am. Soc. Nephrol. 13 (2002) 2384-2398
28. Quarmby L.M., and Parker J.D. Cilia and the cell cycle?. J. Cell Biol. 169 (2005) 707-710
29. O'Connell M.J., Krien M.J., and Hunter T. Never say never. The NIMA-related protein kinases in mitotic control. Trends Cell Biol. 13 (2003) 221-228
30. Mahjoub M.R., Qasim Rasi M., and Quarmby L.M. A NIMA-related kinase, Fa2p, localizes to a novel site in the proximal cilia of Chlamydomonas and mouse kidney cells. Mol. Biol. Cell 15 (2004) 5172-5186
31. Morgan D., Eley L., Sayer J., Strachan T., Yates L.M., Craighead A.S., and Goodship J.A. Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle. Hum. Mol. Genet. 11 (2002) 3345-3350
32. Kim J.C., Badano J.L., Sibold S., Esmail M.A., Hill J., Hoskins B.E., Leitch C.C., Venner K., Ansley S.J., Ross A.J., et al. The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression. Nat. Genet. 36 (2004) 462-470
33. Biggins S., and Rose M.D. Direct interaction between yeast spindle pole body components: Kar1p is required for Cdc31p localization to the spindle pole body. J. Cell Biol. 125 (1994) 843-852
34. Salisbury J.L. Centrin, centrosomes, and mitotic spindle poles. Curr. Opin. Cell Biol. 7 (1995) 39-45
35. McNally F.J., and Thomas S. Katanin is responsible for the M-phase microtubule-severing activity in Xenopus eggs. Mol. Biol. Cell 9 (1998) 1847-1861
36. Dymek E.E., Lefebvre P.A., and Smith E.F. PF15p is the Chlamydomonas homologue of the Katanin p80 subunit and is required for assembly of flagellar central microtubules. Eukaryot. Cell 3 (2004) 870-879
37. Lohret T.A., Zhao L., and Quarmby L.M. Cloning of Chlamydomonas p60 katanin and localization to the site of outer doublet severing during deflagellation. Cell Motil. Cytoskeleton 43 (1999) 221-231
38. Ansley S.J., Badano J.L., Blacque O.E., Hill J., Hoskins B.E., Leitch C.C., Kim J.C., Ross A.J., Eichers E.R., Teslovich T.M., et al. Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome. Nature 425 (2003) 628-633
39. Rieder C.L., Faruki S., and Khodjakov A. The centrosome in vertebrates: More than a microtubule-organizing center. Trends Cell Biol. 11 (2001) 413-419
40. Harris E.H. The Chlamydomonas Sourcebook: A Comprehensive Guide to Biology and Laboratory Use (1989), Academic Press, San Diego, CA
41. Kindle K.L. High-frequency nuclear transformation of Chlamydomonas reinhardtii. Proc. Natl. Acad. Sci. USA 87 (1990) 1228-1232
42. Bordier C. Phase separation of integral membrane proteins in Triton X-114 solution. J. Biol. Chem. 256 (1981) 1604-1607
43. Wessel D., and Flugge U.I. A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids. Anal. Biochem. 138 (1984) 141-143
44. Deane J.A., Cole D.G., Seeley E.S., Diener D.R., and Rosenbaum J.L. Localization of intraflagellar transport protein IFT52 identifies basal body transitional fibers as the docking site for IFT particles. Curr. Biol. 11 (2001) 1586-1590
45. Huang K., and Beck C.F. Phototropin is the blue-light receptor that controls multiple steps in the sexual life cycle of the green alga Chlamydomonas reinhardtii. Proc. Natl. Acad. Sci. USA 100 (2003) 6269-6274
46. Fuhrmann M., Oertel W., and Hegemann P. A synthetic gene coding for the green fluorescent protein (GFP) is a versatile reporter in Chlamydomonas reinhardtii. Plant J. 19 (1999) 353-361
47. Popov N., Schmitt M., Schulzeck S., and Matthies H. Reliable micromethod for determination of the protein content in tissue homogenates. Acta Biol. Med. Ger. 34 (1975) 1441-1446