메뉴 건너뛰기




Volumn 3, Issue 1, 2011, Pages 97-106

Immunotherapy targeting colon cancer stem cells

Author keywords

T cells; cancer stem cells; chemoresistance; immunotherapy; NK cell

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AMINOBISPHOSPHONATE DERIVATIVE; BISPHOSPHONIC ACID DERIVATIVE; HISTONE DEACETYLASE INHIBITOR; TUMOR ANTIGEN; UNCLASSIFIED DRUG; ZOLEDRONIC ACID;

EID: 78650568825     PISSN: 1750743X     EISSN: None     Source Type: Journal    
DOI: 10.2217/imt.10.87     Document Type: Review
Times cited : (18)

References (86)
  • 2
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • DOI 10.1038/nm0797-730
    • Bonnet D, Dick JE: Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat. Med. 3(7), 730-737 (1997). (Pubitemid 27298715)
    • (1997) Nature Medicine , vol.3 , Issue.7 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 4
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
    • DOI 10.1038/nature05372, PII NATURE05372
    • O'brien C, Pollett A, Gallinger S, Dick JE: A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445(7123), 106-110 (2007). (Pubitemid 46067310)
    • (2007) Nature , vol.445 , Issue.7123 , pp. 106-110
    • O'Brien, C.A.1    Pollett, A.2    Gallinger, S.3    Dick, J.E.4
  • 6
    • 59049106578 scopus 로고    scopus 로고
    • Crypt stem cells as the cells-of-origin of intestinal cancer
    • Barker N, Ridgway RA, Van Es JH et al.: Crypt stem cells as the cells-of-origin of intestinal cancer. Nature 457(7229), 608-611 (2009).
    • (2009) Nature , vol.457 , Issue.7229 , pp. 608-611
    • Barker, N.1    Ridgway, R.A.2    Van Es, J.H.3
  • 7
    • 33745728170 scopus 로고    scopus 로고
    • Hedgehog signaling and BMI-1 regulate self-renewal of normal and malignant human mammary stem cells
    • Liu S, Dontu G, Mantle ID et al.: Hedgehog signaling and BMI-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res. 66(12), 6063-6071 (2006).
    • (2006) Cancer Res. , vol.66 , Issue.12 , pp. 6063-6071
    • Liu, S.1    Dontu, G.2    Mantle, I.D.3
  • 10
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • DOI 10.1038/nrc1590
    • Dean M, Fojo T, Bates S: Tumor stem cells and drug resistance. Nat. Rev. Cancer 5(4), 275-284 (2005). (Pubitemid 40488633)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.4 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 11
    • 40549084643 scopus 로고    scopus 로고
    • IL-4-mediated drug resistance in colon cancer stem cells
    • Todaro M, Perez Alea M, Scopelliti A, Medema JP, Stassi G: IL-4-mediated drug resistance in colon cancer stem cells. Cell Cycle 7(3), 309-313 (2008). (Pubitemid 351366493)
    • (2008) Cell Cycle , vol.7 , Issue.3 , pp. 309-313
    • Todaro, M.1    Alea, M.P.2    Scopelliti, A.3    Medema, J.P.4    Stassi, G.5
  • 13
    • 59049087696 scopus 로고    scopus 로고
    • Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation
    • Zhu L, Gibson P, Currle DS et al.: Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation. Nature 457(7229), 603-607 (2009).
    • (2009) Nature , vol.457 , Issue.7229 , pp. 603-607
    • Zhu, L.1    Gibson, P.2    Currle, D.S.3
  • 14
    • 18944407603 scopus 로고    scopus 로고
    • Mammary stem cells, self-renewal pathways, and carcinogenesis
    • DOI 10.1186/bcr1021, 86
    • Liu S, Dontu G, Wicha MS: Mammary stem cells, self-renewal pathways, and carcinogenesis. Breast Cancer Res. 7(3), 86-95 (2005). (Pubitemid 40704127)
    • (2005) Breast Cancer Research , vol.7 , Issue.3 , pp. 86-95
    • Liu, S.1    Dontu, G.2    Wicha, M.S.3
  • 15
    • 51649111430 scopus 로고    scopus 로고
    • Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity
    • Highlights colon cancer stem cell properties
    • Vermeulen L, Todaro M, De Sousa Mello F et al.: Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity. Proc. Natl Acad. Sci. USA 105(36), 13427-13432 (2008). n Highlights colon cancer stem cell properties.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , Issue.36 , pp. 13427-13432
    • Vermeulen, L.1    Todaro, M.2    De Sousa Mello, F.3
  • 16
    • 60549111070 scopus 로고    scopus 로고
    • Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature
    • Charafe-Jauffret E, Ginestier C, Iovino F et al.: Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature. Cancer Res. 69(4), 1302-1313 (2009).
    • (2009) Cancer Res. , vol.69 , Issue.4 , pp. 1302-1313
    • Charafe-Jauffret, E.1    Ginestier, C.2    Iovino, F.3
  • 17
    • 74949129868 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer
    • Charafe-Jauffret E, Ginestier C, Iovino F et al.: Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer. Clin. Cancer Res. 16(1), 45-55
    • Clin. Cancer Res. , vol.16 , Issue.1 , pp. 45-55
    • Charafe-Jauffret, E.1    Ginestier, C.2    Iovino, F.3
  • 18
    • 75449106680 scopus 로고    scopus 로고
    • Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patients
    • Aktas B, Tewes M, Fehm T, Hauch S, Kimmig R, Kasimir-Bauer S: Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patients. Breast Cancer Res. 11(4), R46 (2009).
    • (2009) Breast Cancer Res. , vol.11 , Issue.4
    • Aktas, B.1    Tewes, M.2    Fehm, T.3    Hauch, S.4    Kimmig, R.5    Kasimir-Bauer, S.6
  • 19
    • 33750306612 scopus 로고    scopus 로고
    • Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype
    • DOI 10.1158/1078-0432.CCR-06-0169
    • Balic M, Lin H, Young L et al.: Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype. Clin. Cancer Res. 12(19), 5615-5621 (2006). (Pubitemid 44629587)
    • (2006) Clinical Cancer Research , vol.12 , Issue.19 , pp. 5615-5621
    • Balic, M.1    Lin, H.2    Young, L.3    Hawes, D.4    Giuliano, A.5    McNamara, G.6    Datar, R.H.7    Cote, R.J.8
  • 20
    • 0346724511 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and its implications for fibrosis
    • DOI 10.1172/JCI200320530
    • Kalluri R, Neilson EG: Epithelial-mesenchymal transition and its implications for fibrosis. J. Clin. Invest. 112(12), 1776-1784 (2003). (Pubitemid 38063698)
    • (2003) Journal of Clinical Investigation , vol.112 , Issue.12 , pp. 1776-1784
    • Kalluri, R.1    Neilson, E.G.2
  • 22
    • 42549145056 scopus 로고    scopus 로고
    • Acquired and innate resistance to the cancer-specific apoptosis-inducing cytokine, mda-7/IL-24: Not insurmountable therapeutic problems
    • Sarkar D, Dent P, Curiel DT, Fisher PB: Acquired and innate resistance to the cancer-specific apoptosis-inducing cytokine, MDA-7/IL-24: not insurmountable therapeutic problems. Cancer Biol. Ther. 7(1), 109-112 (2008). (Pubitemid 351590462)
    • (2008) Cancer Biology and Therapy , vol.7 , Issue.1 , pp. 109-112
    • Sarkar, D.1    Dent, P.2    Curiel, D.T.3    Fisher, P.B.4
  • 23
    • 38049043823 scopus 로고    scopus 로고
    • The basal-like breast carcinoma phenotype is regulated by slug gene expression
    • Storci G, Sansone P, Trere D et al.: The basal-like breast carcinoma phenotype is regulated by slug gene expression. J. Pathol. 214(1), 25-37 (2008).
    • (2008) J. Pathol. , vol.214 , Issue.1 , pp. 25-37
    • Storci, G.1    Sansone, P.2    Trere, D.3
  • 24
    • 42649137241 scopus 로고    scopus 로고
    • Mechanisms of disease: Epithelial-mesenchymal transition - Does cellular plasticity fuel neoplastic progression?
    • DOI 10.1038/ncponc1089, PII NCPONC1089
    • Turley EA, Veiseh M, Radisky DC, Bissell MJ: Mechanisms of disease: epithelial-mesenchymal transition - does cellular plasticity fuel neoplastic progression? Nat. Clin. Pract. Oncol. 5(5), 280-290 (2008). (Pubitemid 351594144)
    • (2008) Nature Clinical Practice Oncology , vol.5 , Issue.5 , pp. 280-290
    • Turley, E.A.1    Veiseh, M.2    Radisky, D.C.3    Bissell, M.J.4
  • 25
    • 48649087927 scopus 로고    scopus 로고
    • Monitoring serial changes in circulating human breast cancer cells in murine xenograft models
    • Eliane JP, Repollet M, Luker KE et al.: Monitoring serial changes in circulating human breast cancer cells in murine xenograft models. Cancer Res. 68(14), 5529-5532 (2008).
    • (2008) Cancer Res. , vol.68 , Issue.14 , pp. 5529-5532
    • Eliane, J.P.1    Repollet, M.2    Luker, K.E.3
  • 26
    • 25444495269 scopus 로고    scopus 로고
    • Migrating cancer stem cells - An integrated concept of malignant tumour progression
    • DOI 10.1038/nrc1694, PII N1694
    • Brabletz T, Jung A, Spaderna S, Hlubek F, Kirchner T: Opinion: migrating cancer stem cells - an integrated concept of malignant tumor progression. Nat. Rev. Cancer 5(9), 744-749 (2005). (Pubitemid 41486367)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.9 , pp. 744-749
    • Brabletz, T.1    Jung, A.2    Spaderna, S.3    Hlubek, F.4    Kirchner, T.5
  • 27
    • 33646883964 scopus 로고    scopus 로고
    • Embryonic transcription factors in human breast cancer
    • DOI 10.1080/15216540600686870, PII K443547205273
    • Briegel KJ: Embryonic transcription factors in human breast cancer. IUBMB Life 58(3), 123-132 (2006). (Pubitemid 43786037)
    • (2006) IUBMB Life , vol.58 , Issue.3 , pp. 123-132
    • Briegel, K.J.1
  • 29
    • 34249289041 scopus 로고    scopus 로고
    • Snail, ZEB and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
    • DOI 10.1038/nrc2131, PII NRC2131
    • Peinado H, Olmeda D, Cano A: Snail, zeb and bhlh factors in tumor progression: an alliance against the epithelial phenotype? Nat. Rev. Cancer 7(6), 415-428 (2007). (Pubitemid 46809165)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.6 , pp. 415-428
    • Peinado, H.1    Olmeda, D.2    Cano, A.3
  • 30
    • 54449085718 scopus 로고    scopus 로고
    • Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers
    • Dumont N, Wilson MB, Crawford YG, Reynolds PA, Sigaroudinia M, Tlsty TD: Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers. Proc. Natl Acad. Sci. USA 105(39), 14867-14872 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , Issue.39 , pp. 14867-14872
    • Dumont, N.1    Wilson, M.B.2    Crawford, Y.G.3    Reynolds, P.A.4    Sigaroudinia, M.5    Tlsty, T.D.6
  • 31
    • 67650496215 scopus 로고    scopus 로고
    • A novel lung metastasis signature links wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer
    • Dimeo TA, Anderson K, Phadke P et al.: A novel lung metastasis signature links wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer. Cancer Res. 69(13), 5364-5373 (2009).
    • (2009) Cancer Res. , vol.69 , Issue.13 , pp. 5364-5373
    • Dimeo, T.A.1    Anderson, K.2    Phadke, P.3
  • 32
    • 70349859809 scopus 로고    scopus 로고
    • Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells
    • Kurrey NK, Jalgaonkar SP, Joglekar AV et al.: Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells. Stem Cells 27(9), 2059-2068 (2009).
    • (2009) Stem Cells , vol.27 , Issue.9 , pp. 2059-2068
    • Kurrey, N.K.1    Jalgaonkar, S.P.2    Joglekar, A.V.3
  • 34
    • 77957375136 scopus 로고    scopus 로고
    • AACR special conference on epithelial-mesenchymal transition and cancer progression and treatment
    • Roussos ET, Keckesova Z, Haley JD, Epstein DM, Weinberg RA, Condeelis JS: AACR special conference on epithelial-mesenchymal transition and cancer progression and treatment. Cancer Res. 70(19), 7360-7364 (2010).
    • (2010) Cancer Res. , vol.70 , Issue.19 , pp. 7360-7364
    • Roussos, E.T.1    Keckesova, Z.2    Haley, J.D.3    Epstein, D.M.4    Weinberg, R.A.5    Condeelis, J.S.6
  • 36
    • 77956520374 scopus 로고    scopus 로고
    • Survivin is regulated by interleukin-4 in colon cancer stem cells
    • Stefano AB, Iovino F, Lombardo Y et al.: Survivin is regulated by interleukin-4 in colon cancer stem cells. J. Cell Physiol. 225(2), 555-561 (2010).
    • (2010) J. Cell Physiol. , vol.225 , Issue.2 , pp. 555-561
    • Stefano, A.B.1    Iovino, F.2    Lombardo, Y.3
  • 39
    • 59449088943 scopus 로고    scopus 로고
    • Treatment of ovarian cancer cell lines with 5-aza-2'-deoxycytidine upregulates the expression of cancer-testis antigens and class I major histocompatibility complex-encoded molecules
    • Adair SJ, Hogan KT: Treatment of ovarian cancer cell lines with 5-aza-2'-deoxycytidine upregulates the expression of cancer-testis antigens and class I major histocompatibility complex-encoded molecules. Cancer Immunol. Immunother. 58(4), 589-601 (2009).
    • (2009) Cancer Immunol. Immunother. , vol.58 , Issue.4 , pp. 589-601
    • Adair, S.J.1    Hogan, K.T.2
  • 42
    • 33645091240 scopus 로고    scopus 로고
    • TNF-related apoptosis-inducing ligand as a therapeutic agent in autoimmunity and cancer
    • Cretney E, Shanker A, Yagita H, Smyth MJ, Sayers TJ: TNF-related apoptosis-inducing ligand as a therapeutic agent in autoimmunity and cancer. Immunol. Cell Biol. 84(1), 87-98 (2006).
    • (2006) Immunol. Cell Biol. , vol.84 , Issue.1 , pp. 87-98
    • Cretney, E.1    Shanker, A.2    Yagita, H.3    Smyth, M.J.4    Sayers, T.J.5
  • 45
    • 0028824111 scopus 로고
    • + T cells into human colorectal cancer: Flow cytometric analysis of TCR-γ δ expression in tumour-infiltrating lymphocytes
    • + T cells into human colorectal cancer: flow cytometric analysis of TCR-γ δ expression in tumour-infiltrating lymphocytes. Clin. Exp. Immunol. 102(1), 167-173 (1995).
    • (1995) Clin. Exp. Immunol. , vol.102 , Issue.1 , pp. 167-173
    • Watanabe, N.1    Hizuta, A.2    Tanaka, N.3    Orita, K.4
  • 46
    • 0035914134 scopus 로고    scopus 로고
    • Regulation of cutaneous malignancy by γδ T cells
    • Girardi M, Oppenheim DE, Steele CR et al.: Regulation of cutaneous malignancy by γδ T cells. Science 294(5542), 605-609 (2001).
    • (2001) Science , vol.294 , Issue.5542 , pp. 605-609
    • Girardi, M.1    Oppenheim, D.E.2    Steele, C.R.3
  • 47
    • 17144398106 scopus 로고    scopus 로고
    • Ex vivo expanded human Vγ9Vδ2+ γδ-T cells mediate innate antitumor activity against human prostate cancer cells in vitro
    • DOI 10.1097/01.ju.0000154355.45816.0b
    • + γδ-T cells mediate innate antitumor activity against human prostate cancer cells in vitro. J. Urol. 173(5), 1552-1556 (2005). (Pubitemid 40524770)
    • (2005) Journal of Urology , vol.173 , Issue.5 , pp. 1552-1556
    • Liu, Z.1    Guo, B.L.2    Gehrs, B.C.3    Nan, L.4    Lopez, R.D.5
  • 48
    • 9144241718 scopus 로고    scopus 로고
    • Characterization of tumor reactivity of human Vγ9Vδ2 γδ T cells in vitro and in SCID mice in vivo
    • Kabelitz D, Wesch D, Pitters E, Zoller M: Characterization of tumor reactivity of human Vγ9Vδ2 γδ T cells in vitro and in scid mice in vivo. J. Immunol. 173(11), 6767-6776 (2004). (Pubitemid 39541063)
    • (2004) Journal of Immunology , vol.173 , Issue.11 , pp. 6767-6776
    • Kabelitz, D.1    Wesch, D.2    Pitters, E.3    Zoller, M.4
  • 49
    • 33748131230 scopus 로고    scopus 로고
    • Human Vγ9Vδ2 T cells: Promising new leads for immunotherapy of infections and tumors
    • DOI 10.1016/j.coi.2006.07.002, PII S0952791506001385, Innate Lymphocytes/Transplantation/Immunogenetics
    • Bonneville M, Scotet E: Human Vγ9Vδ2 T cells: promising new leads for immunotherapy of infections and tumors. Curr. Opin. Immunol. 18(5), 539-546 (2006). (Pubitemid 44311448)
    • (2006) Current Opinion in Immunology , vol.18 , Issue.5 , pp. 539-546
    • Bonneville, M.1    Scotet, E.2
  • 50
    • 77951894970 scopus 로고    scopus 로고
    • Vγ9Vδ 2 T lymphocytes efficiently recognize and kill zoledronate-sensitized, imatinib-sensitive, and imatinib-resistant chronic myelogenous leukemia cells
    • D'asaro M, La Mendola C, Di Liberto D et al.: Vγ9Vδ 2 T lymphocytes efficiently recognize and kill zoledronate-sensitized, imatinib-sensitive, and imatinib-resistant chronic myelogenous leukemia cells. J. Immunol. 184(6), 3260-3268 (2010).
    • (2010) J. Immunol. , vol.184 , Issue.6 , pp. 3260-3268
    • D'asaro, M.1    La Mendola, C.2    Di Liberto, D.3
  • 51
    • 0037304115 scopus 로고    scopus 로고
    • Antitumor effects of bisphosphonates
    • Green JR: Antitumor effects of bisphosphonates. Cancer 97(Suppl. 3), 840-847 (2003).
    • (2003) Cancer , vol.97 , Issue.SUPPL. 3 , pp. 840-847
    • Green, J.R.1
  • 52
    • 20444486612 scopus 로고    scopus 로고
    • Bisphosphonates and cancer-induced bone disease: Beyond their antiresorptive activity
    • DOI 10.1158/0008-5472.CAN-05-0264
    • Clezardin P, Ebetino FH, Fournier PG: Bisphosphonates and cancer-induced bone disease: beyond their antiresorptive activity. Cancer Res. 65(12), 4971-4974 (2005). (Pubitemid 40827299)
    • (2005) Cancer Research , vol.65 , Issue.12 , pp. 4971-4974
    • Clezardin, P.1    Ebetino, F.H.2    Fournier, P.G.J.3
  • 53
    • 0035438385 scopus 로고    scopus 로고
    • Vγ2Vδ2 T-cell receptor-mediated recognition of aminobisphosphonates
    • Das H, Wang L, Kamath A, Bukowski JF: Vγ2Vδ2 T-cell receptor-mediated recognition of aminobisphosphonates. Blood 98(5), 1616-1618 (2001).
    • (2001) Blood , vol.98 , Issue.5 , pp. 1616-1618
    • Das, H.1    Wang, L.2    Kamath, A.3    Bukowski, J.F.4
  • 54
    • 0037455013 scopus 로고    scopus 로고
    • Human T cell receptor γδ cells recognize endogenous mevalonate metabolites in tumor cells
    • DOI 10.1084/jem.20021500
    • Gober HJ, Kistowska M, Angman L, Jeno P, Mori L, De Libero G: Human T cell receptor γδ cells recognize endogenous mevalonate metabolites in tumor cells. J. Exp. Med. 197(2), 163-168 (2003). (Pubitemid 36152311)
    • (2003) Journal of Experimental Medicine , vol.197 , Issue.2 , pp. 163-168
    • Gober, H.-J.1    Kistowska, M.2    Angman, L.3    Jeno, P.4    Mori, L.5    De Libero, G.6
  • 55
    • 0035500925 scopus 로고    scopus 로고
    • Targeting of tumor cells for human γδ T cells by nonpeptide antigens
    • Kato Y, Tanaka Y, Miyagawa F, Yamashita S, Minato N: Targeting of tumor cells for human γδ T cells by nonpeptide antigens. J. Immunol. 167(9), 5092-5098 (2001). (Pubitemid 33009743)
    • (2001) Journal of Immunology , vol.167 , Issue.9 , pp. 5092-5098
    • Kato, Y.1    Tanaka, Y.2    Miyagawa, F.3    Yamashita, S.4    Minato, N.5
  • 56
    • 34248219009 scopus 로고    scopus 로고
    • Chemotherapy and zoledronate sensitize solid tumour cells to Vγ9Vδ2 T cell cytotoxicity
    • DOI 10.1007/s00262-007-0279-2
    • Mattarollo SR, Kenna T, Nieda M, Nicol AJ: Chemotherapy and zoledronate sensitize solid tumour cells to Vγ9Vδ2 T cell cytotoxicity. Cancer Immunol. Immunother. 56(8), 1285-1297 (2007). (Pubitemid 46763941)
    • (2007) Cancer Immunology, Immunotherapy , vol.56 , Issue.8 , pp. 1285-1297
    • Mattarollo, S.R.1    Kenna, T.2    Nieda, M.3    Nicol, A.J.4
  • 59
    • 4644239416 scopus 로고    scopus 로고
    • Fas-Fas ligand interactions are essential for the binding to and killing of activated macrophages by γδ T cells
    • Dalton JE, Howell G, Pearson J, Scott P, Carding SR: Fas-Fas ligand interactions are essential for the binding to and killing of activated macrophages by γδ T cells. J. Immunol. 173(6), 3660-3667 (2004). (Pubitemid 39280726)
    • (2004) Journal of Immunology , vol.173 , Issue.6 , pp. 3660-3667
    • Dalton, J.E.1    Howell, G.2    Pearson, J.3    Scott, P.4    Carding, S.R.5
  • 61
    • 0036582288 scopus 로고    scopus 로고
    • γδ T cells: Functional plasticity and heterogeneity
    • Carding SR, Egan PJ: γδ T cells: functional plasticity and heterogeneity. Nat. Rev. Immunol. 2(5), 336-345 (2002).
    • (2002) Nat. Rev. Immunol. , vol.2 , Issue.5 , pp. 336-345
    • Carding, S.R.1    Egan, P.J.2
  • 64
    • 33846813974 scopus 로고    scopus 로고
    • Safety profile and anti-tumor effects of adoptive immunotherapy using gamma-delta T cells against advanced renal cell carcinoma: A pilot study
    • DOI 10.1007/s00262-006-0199-6
    • Kobayashi H, Tanaka Y, Yagi J et al.: Safety profile and anti-tumor effects of adoptive immunotherapy using γδ T cells against advanced renal cell carcinoma: a pilot study. Cancer Immunol. Immunother. 56(4), 469-476 (2007). (Pubitemid 46204533)
    • (2007) Cancer Immunology, Immunotherapy , vol.56 , Issue.4 , pp. 469-476
    • Kobayashi, H.1    Tanaka, Y.2    Yagi, J.3    Osaka, Y.4    Nakazawa, H.5    Uchiyama, T.6    Minato, N.7    Toma, H.8
  • 65
    • 67449135832 scopus 로고    scopus 로고
    • Efficient killing of human colon cancer stem cells by γδ T lymphocytes
    • Suggested that γδ T lymphocytes kill colon cancer stem cells
    • Todaro M, D'asaro M, Caccamo N et al.: Efficient killing of human colon cancer stem cells by γδ T lymphocytes. J. Immunol. 182(11), 7287-7296 (2009). n Suggested that γδ T lymphocytes kill colon cancer stem cells.
    • (2009) J. Immunol. , vol.182 , Issue.11 , pp. 7287-7296
    • Todaro, M.1    D'asaro, M.2    Caccamo, N.3
  • 66
    • 1542380606 scopus 로고    scopus 로고
    • Unravelling natural killer cell function: Triggering and inhibitory human NK receptors
    • DOI 10.1038/sj.emboj.7600019
    • Moretta L, Moretta A: Unravelling natural killer cell function: triggering and inhibitory human NK receptors. EMBO J. 23(2), 255-259 (2004). (Pubitemid 38294490)
    • (2004) EMBO Journal , vol.23 , Issue.2 , pp. 255-259
    • Moretta, L.1    Moretta, A.2
  • 70
    • 0033991158 scopus 로고    scopus 로고
    • Escape of human solid tumors from T-cell recognition: Molecular mechanisms and functional significance
    • Marincola FM, Jaffee EM, Hicklin DJ, Ferrone S: Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance. Adv. Immunol. 74, 181-273 (2000).
    • (2000) Adv. Immunol. , vol.74 , pp. 181-273
    • Marincola, F.M.1    Jaffee, E.M.2    Hicklin, D.J.3    Ferrone, S.4
  • 71
    • 0036038734 scopus 로고    scopus 로고
    • Multiple mechanisms generate HLA class I altered phenotypes in laryngeal carcinomas: High frequency of HLA haplotype loss associated with loss of heterozygosity in chromosome region 6p21
    • DOI 10.1007/s00262-002-0296-0
    • Maleno I, Lopez-Nevot MA, Cabrera T, Salinero J, Garrido F: Multiple mechanisms generate HLA class I altered phenotypes in laryngeal carcinomas: high frequency of HLA haplotype loss associated with loss of heterozygosity in chromosome region 6p21. Cancer Immunol. Immunother. 51(7), 389-396 (2002). (Pubitemid 35002044)
    • (2002) Cancer Immunology, Immunotherapy , vol.51 , Issue.7 , pp. 389-396
    • Maleno, I.1    Lopez-Nevot, M.2    Cabrera, T.3    Salinero, J.4    Garrido, F.5
  • 75
    • 0038666364 scopus 로고    scopus 로고
    • Characterization of human lymphocyte antigen class I antigen-processing machinery defects in renal cell carcinoma lesions with special emphasis on transporter-associated with antigen-processing down-regulation
    • Seliger B, Atkins D, Bock M et al.: Characterization of human lymphocyte antigen class I antigen-processing machinery defects in renal cell carcinoma lesions with special emphasis on transporter-associated with antigen-processing down-regulation. Clin. Cancer Res. 9(5), 1721-1727 (2003). (Pubitemid 36554596)
    • (2003) Clinical Cancer Research , vol.9 , Issue.5 , pp. 1721-1727
    • Seliger, B.1    Atkins, D.2    Bock, M.3    Ritz, U.4    Ferrone, S.5    Huber, C.6    Storkel, S.7
  • 77
    • 0033522147 scopus 로고    scopus 로고
    • γ/δ T-cell stimulation by pamidronate
    • Kunzmann V, Bauer E, Wilhelm M: γ/δ T-cell stimulation by pamidronate. N. Engl. J. Med. 340(9), 737-738 (1999).
    • (1999) N. Engl. J. Med. , vol.340 , Issue.9 , pp. 737-738
    • Kunzmann, V.1    Bauer, E.2    Wilhelm, M.3
  • 80
    • 67649864077 scopus 로고    scopus 로고
    • Natural killer cells kill human melanoma cells with characteristics of cancer stem cells
    • Pietra G, Manzini C, Vitale M et al.: Natural killer cells kill human melanoma cells with characteristics of cancer stem cells. Int. Immunol. 21(7), 793-801 (2009).
    • (2009) Int. Immunol. , vol.21 , Issue.7 , pp. 793-801
    • Pietra, G.1    Manzini, C.2    Vitale, M.3
  • 83
    • 34447648954 scopus 로고    scopus 로고
    • + glioma cells: Possible targets of immunotherapy
    • Discusses future targets of immunotherapy
    • + glioma cells: possible targets of immunotherapy. J. Neurooncol. 83(2), 121-131 (2007). n Discusses future targets of immunotherapy.
    • (2007) J. Neurooncol. , vol.83 , Issue.2 , pp. 121-131
    • Wu, A.1    Wiesner, S.2    Xiao, J.3
  • 86
    • 33646755569 scopus 로고    scopus 로고
    • Cancer immunosurveillance and immunoediting: The roles of immunity in suppressing tumor development and shaping tumor immunogenicity
    • Smyth MJ, Dunn GP, Schreiber RD: Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity. Adv. Immunol. 90, 1-50 (2006).
    • (2006) Adv. Immunol. , vol.90 , pp. 1-50
    • Smyth, M.J.1    Dunn, G.P.2    Schreiber, R.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.