Symmetry Complementarity-Guided Design of Anthrax Toxin Inhibitors Based on β-Cyclodextrin: Synthesis and Relative Activities of Face-Selective Functionalized Polycationic Clusters

ChemMedChem

Volumn 6, Issue 1, 2011, Pages 181-192

  Díaz Moscoso, Alejandro ^a   Méndez Ardoy, Alejandro ^b   Ortega Caballero, Fernando ^b   Benito, Juan M ^a   Ortiz Mellet, Carmen ^b   Defaye, Jacques ^c   Robinson, Tanisha M ^d   Yohannes, Adiamseged ^d   Karginov, Vladimir A ^d   García Fernández, José M ^a  

^a INSTITUTO DE INVESTIGACIONES QUÍMICAS   (Spain)

^b UNIVERSITY OF SEVILLE   (Spain)

^c UNIV GRENOBLE ALPES   (France)

^d Innovative Biologics Inc   (United States)

Author keywords

Anthrax; Click chemistry; Cyclodextrins; Symmetry complementarity; Toxin inhibitors

Indexed keywords

ANTHRAX TOXIN; BETA CYCLODEXTRIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL VIABILITY; CONTROLLED STUDY; CYCLOADDITION; CYTOSOL; CYTOTOXICITY; DRUG ACTIVITY; DRUG DESIGN; DRUG SYNTHESIS; IC 50; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 78650556056     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201000419     Document Type: Article

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