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European Journal of Medicinal Chemistry

Volumn 46, Issue 1, 2011, Pages 229-235

Synthesis and in vitro anti-tumor activity of new oxadiazole thioglycosides

(4) Abu Zaied, M A a El Telbani, E M a Elgemeie, G H b Nawwar, G A M a

a NATIONAL RESEARCH CENTRE (Egypt)

b Helwan University (Egypt)

Author keywords

1,3,4 Oxadiazole; 5 Flurouracil; Anti tumor activities; Tamoxifen; Thiogycosides; Toxicity

Indexed keywords

1,3,4 OXADIAZOLE DERIVATIVE; 4 [[(3 ISOBUTYL 1 PHENYL 1H PYRAZOL 4 YL)METHYLENE]AMINO] 6 METHYL 3 (2',3',4',6' TETRA O ACEYL BETA DEXTRO GLUCOPYRANOSYLTHIO) 1,2,4 TRIAZIN 5(4H) ONE; 5 (3 ISOBUTYL 1 PHENYL 1H PYRAZOL 4 YL) 2 (2',3',4',6' TETRA O ACEYL BETA DEXTRO GLUCOPYRANOSYLTHIO) 1,3,4 OXADIAZOLE; 5 (3 ISOBUTYL 1 PHENYL 1H PYRAZOL 4 YL) 2 [[(METHYLTHIO)METHYL]THIO] 1,3,4 OXADIAZOLE; 5 (3 ISOBUTYL 1 PHENYL 1H PYRAZOLE 4 YL) 1,3,4 OXADIAZOLE 2 THIOL; ALDEHYDE; ANTINEOPLASTIC AGENT; FLUOROURACIL; KETONE; PHENYLHYDRAZINE; TAMOXIFEN; THIOGLYCOSIDE; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN HEPG2; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; IC 50; LD 50; MALE; NONHUMAN; POLYMERIZATION; RAT; SINGLE DRUG DOSE; STRUCTURE ACTIVITY RELATION; VILSMEIER HAACK REACTION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG DESIGN; HUMANS; INHIBITORY CONCENTRATION 50; MALE; OXADIAZOLES; RATS; RATS, WISTAR; THIOGLYCOSIDES;

EID: 78650514875 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2010.11.008 Document Type: Article

Times cited : (98)

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