메뉴 건너뛰기




Volumn 182, Issue 2-3, 2009, Pages 183-190

Novel nitro-oxy derivatives of celecoxib for the regulation of colon cancer cell growth

Author keywords

Catenin E cadherin; Colon cancer; Cyclooxygenase 2; NO celecoxib; Proliferation

Indexed keywords

BETA CATENIN; CELECOXIB; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; NITROOXYCELECOXIB DERIVATIVE; UNCLASSIFIED DRUG; UVOMORULIN;

EID: 70350129705     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2009.08.006     Document Type: Article
Times cited : (20)

References (57)
  • 1
    • 34547923201 scopus 로고    scopus 로고
    • The cyclooxygenase-2-mediated prostaglandin signaling is causally related to epithelial carcinogenesis
    • Müller-Decker K., and Fürstenberger G. The cyclooxygenase-2-mediated prostaglandin signaling is causally related to epithelial carcinogenesis. Mol. Carcinog. 46 (2007) 705-710
    • (2007) Mol. Carcinog. , vol.46 , pp. 705-710
    • Müller-Decker, K.1    Fürstenberger, G.2
  • 3
    • 38849104805 scopus 로고    scopus 로고
    • Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) and inhibition of cyclooxygenase 2 (COX2) attenuate colon carcinogenesis through independent signaling mechanisms
    • Hollingshead H.E., Borland M.G., Billin A.N., Willson T.M., Gonzalez F.J., and Peters J.M. Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) and inhibition of cyclooxygenase 2 (COX2) attenuate colon carcinogenesis through independent signaling mechanisms. Carcinogenesis 29 (2008) 169-176
    • (2008) Carcinogenesis , vol.29 , pp. 169-176
    • Hollingshead, H.E.1    Borland, M.G.2    Billin, A.N.3    Willson, T.M.4    Gonzalez, F.J.5    Peters, J.M.6
  • 4
    • 29244449354 scopus 로고    scopus 로고
    • Prostaglandins and cancer
    • Wang D., and Dubois R.N. Prostaglandins and cancer. Gut 55 (2006) 115-122
    • (2006) Gut , vol.55 , pp. 115-122
    • Wang, D.1    Dubois, R.N.2
  • 5
    • 28544444039 scopus 로고    scopus 로고
    • Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis
    • Castellone M.D., Teramoto H., Williams B.O., Druey K.M., and Gutkind J.S. Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis. Science 310 (2005) 1504-1510
    • (2005) Science , vol.310 , pp. 1504-1510
    • Castellone, M.D.1    Teramoto, H.2    Williams, B.O.3    Druey, K.M.4    Gutkind, J.S.5
  • 6
    • 35648988947 scopus 로고    scopus 로고
    • Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene
    • Aoki K., and Taketo M.M. Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene. J. Cell. Sci. 120 (2007) 3327-3335
    • (2007) J. Cell. Sci. , vol.120 , pp. 3327-3335
    • Aoki, K.1    Taketo, M.M.2
  • 7
    • 1942537708 scopus 로고    scopus 로고
    • The significance of the Wnt pathway in the pathology of human cancers
    • Karim R., Tse G., Putti T., Scolyer R., and Lee S. The significance of the Wnt pathway in the pathology of human cancers. Pathology 36 (2004) 120-128
    • (2004) Pathology , vol.36 , pp. 120-128
    • Karim, R.1    Tse, G.2    Putti, T.3    Scolyer, R.4    Lee, S.5
  • 8
    • 0037379779 scopus 로고    scopus 로고
    • Clinical, cellular, and molecular aspects of cancer invasion
    • Mareel M., and Leroy A. Clinical, cellular, and molecular aspects of cancer invasion. Physiol. Rev. 83 (2003) 337-376
    • (2003) Physiol. Rev. , vol.83 , pp. 337-376
    • Mareel, M.1    Leroy, A.2
  • 9
    • 1042267263 scopus 로고    scopus 로고
    • Cell adhesion and signalling by cadherins and Ig-CAMs in cancer
    • Cavallaro U., and Christofori G. Cell adhesion and signalling by cadherins and Ig-CAMs in cancer. Nat. Rev. Cancer 4 (2004) 118-132
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 118-132
    • Cavallaro, U.1    Christofori, G.2
  • 11
    • 28244483194 scopus 로고    scopus 로고
    • Altered localization of p120 catenin during epithelial to mesenchymal transition of colon carcinoma is prognostic for aggressive disease
    • Bellovin D.I., Bates R.C., Muzikansky A., Rimm D.L., and Mercurio A.M. Altered localization of p120 catenin during epithelial to mesenchymal transition of colon carcinoma is prognostic for aggressive disease. Cancer Res. 65 (2005) 10938-10945
    • (2005) Cancer Res. , vol.65 , pp. 10938-10945
    • Bellovin, D.I.1    Bates, R.C.2    Muzikansky, A.3    Rimm, D.L.4    Mercurio, A.M.5
  • 14
    • 0033575796 scopus 로고    scopus 로고
    • The role of cyclooxygenase inhibition in the antineoplastic effects of nonsteroidal antiinflammatory drugs (NSAIDs)
    • Shiff S.J., and Rigas B. The role of cyclooxygenase inhibition in the antineoplastic effects of nonsteroidal antiinflammatory drugs (NSAIDs). J. Exp. Med. 190 (1999) 445-450
    • (1999) J. Exp. Med. , vol.190 , pp. 445-450
    • Shiff, S.J.1    Rigas, B.2
  • 15
    • 0042632585 scopus 로고    scopus 로고
    • Role of COX-independent targets of NSAIDs and related compounds in cancer prevention and treatment
    • Soh J.W., and Weinstein I.B. Role of COX-independent targets of NSAIDs and related compounds in cancer prevention and treatment. Prog. Exp. Tumor Res. 37 (2003) 261-285
    • (2003) Prog. Exp. Tumor Res. , vol.37 , pp. 261-285
    • Soh, J.W.1    Weinstein, I.B.2
  • 16
    • 26244436813 scopus 로고    scopus 로고
    • Cardiovascular effects of coxibs
    • Caporali R., and Montecucco C. Cardiovascular effects of coxibs. Lupus 14 (2005) 785-788
    • (2005) Lupus , vol.14 , pp. 785-788
    • Caporali, R.1    Montecucco, C.2
  • 17
    • 33746841773 scopus 로고    scopus 로고
    • Temporal relationship between use of NSAIDs, including selective COX-2 inhibitors, and cardiovascular risk
    • Motsko S.P., Rascati K.L., Busti A.J., Wilson J.P., Barner J.C., Lawson K.A., and Worchel J. Temporal relationship between use of NSAIDs, including selective COX-2 inhibitors, and cardiovascular risk. Drug Saf. 29 (2006) 621-632
    • (2006) Drug Saf. , vol.29 , pp. 621-632
    • Motsko, S.P.1    Rascati, K.L.2    Busti, A.J.3    Wilson, J.P.4    Barner, J.C.5    Lawson, K.A.6    Worchel, J.7
  • 18
    • 33645869889 scopus 로고    scopus 로고
    • Cardiovascular risk with cyclooxygenase inhibitors: general problem with substance specific differences?
    • Tegeder I., and Geisslinger G. Cardiovascular risk with cyclooxygenase inhibitors: general problem with substance specific differences?. Naunyn Schmiedebergs Arch. Pharmacol. 373 (2006) 1-17
    • (2006) Naunyn Schmiedebergs Arch. Pharmacol. , vol.373 , pp. 1-17
    • Tegeder, I.1    Geisslinger, G.2
  • 19
    • 34848869089 scopus 로고    scopus 로고
    • Cardiovascular effects of cyclooxygenase-2 inhibitors
    • Brophy J.M. Cardiovascular effects of cyclooxygenase-2 inhibitors. Curr. Opin. Gastroenterol. 23 (2007) 617-624
    • (2007) Curr. Opin. Gastroenterol. , vol.23 , pp. 617-624
    • Brophy, J.M.1
  • 20
    • 17144393290 scopus 로고    scopus 로고
    • Adverse cardiovascular effects of the coxibs
    • Dogné J.M., Supuran C.T., and Pratico D. Adverse cardiovascular effects of the coxibs. J. Med. Chem. 48 (2005) 2251-2257
    • (2005) J. Med. Chem. , vol.48 , pp. 2251-2257
    • Dogné, J.M.1    Supuran, C.T.2    Pratico, D.3
  • 21
    • 23244445988 scopus 로고    scopus 로고
    • Cyclooxygenase inhibition and cardiovascular risk
    • Antman E.M., DeMets D., and Loscalzo J. Cyclooxygenase inhibition and cardiovascular risk. Circulation 112 (2005) 759-770
    • (2005) Circulation , vol.112 , pp. 759-770
    • Antman, E.M.1    DeMets, D.2    Loscalzo, J.3
  • 23
    • 0036584678 scopus 로고    scopus 로고
    • NO-releasing NSAIDs and colon cancer chemoprevention: a promising novel approach
    • Rigas B., and Williams J.L. NO-releasing NSAIDs and colon cancer chemoprevention: a promising novel approach. Int. J. Oncol. 20 (2002) 885-890
    • (2002) Int. J. Oncol. , vol.20 , pp. 885-890
    • Rigas, B.1    Williams, J.L.2
  • 24
    • 0038393248 scopus 로고    scopus 로고
    • Nitric oxide-donating non-steroidal anti-inflammatory drugs: the case of nitroderivatives of aspirin
    • Chiroli V., Benedini F., Ongini E., and Del Soldato P. Nitric oxide-donating non-steroidal anti-inflammatory drugs: the case of nitroderivatives of aspirin. Eur. J. Med. Chem. 38 (2003) 441-446
    • (2003) Eur. J. Med. Chem. , vol.38 , pp. 441-446
    • Chiroli, V.1    Benedini, F.2    Ongini, E.3    Del Soldato, P.4
  • 25
    • 34249657760 scopus 로고    scopus 로고
    • The mechanism of action of nitric oxide-donating aspirin
    • Kashfi K., and Rigas B. The mechanism of action of nitric oxide-donating aspirin. Biochem. Biophys. Res. Commun. 358 (2007) 1096-1101
    • (2007) Biochem. Biophys. Res. Commun. , vol.358 , pp. 1096-1101
    • Kashfi, K.1    Rigas, B.2
  • 26
    • 34249008406 scopus 로고    scopus 로고
    • Chemical insights in the concept of hybrid drugs: the antitumor effect of nitric oxide-donating aspirin involves a quinone methide but not nitric oxide nor aspirin
    • Hulsman N., Medema J.P., Bos C., Jongejan A., Leurs R., Smith M.J., de Esch I.J., Richel D., and Wijtmans M. Chemical insights in the concept of hybrid drugs: the antitumor effect of nitric oxide-donating aspirin involves a quinone methide but not nitric oxide nor aspirin. J. Med. Chem. 50 (2007) 2424-2431
    • (2007) J. Med. Chem. , vol.50 , pp. 2424-2431
    • Hulsman, N.1    Medema, J.P.2    Bos, C.3    Jongejan, A.4    Leurs, R.5    Smith, M.J.6    de Esch, I.J.7    Richel, D.8    Wijtmans, M.9
  • 28
    • 34147113829 scopus 로고    scopus 로고
    • NO-donor COX-2 inhibitors. New nitrooxy-substituted 1,5-diarylimidazoles endowed with COX-2 inhibitory and vasodilator properties
    • Chegaev K., Lazzarato L., Tosco P., Cena C., Marini E., Rolando B., Carrupt P.A., Fruttero R., and Gasco A. NO-donor COX-2 inhibitors. New nitrooxy-substituted 1,5-diarylimidazoles endowed with COX-2 inhibitory and vasodilator properties. J. Med. Chem. 50 (2007) 1449-1457
    • (2007) J. Med. Chem. , vol.50 , pp. 1449-1457
    • Chegaev, K.1    Lazzarato, L.2    Tosco, P.3    Cena, C.4    Marini, E.5    Rolando, B.6    Carrupt, P.A.7    Fruttero, R.8    Gasco, A.9
  • 29
    • 15244340003 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of 3,4-diphenyl-1,2,5-oxadiazole-2-oxides and 3,4-diphenyl-1,2,5-oxadiazoles as potential hybrid COX-2 inhibitor/nitric oxide donor agents
    • Velazquez C., Rao P.N.P., McDonald R., and Knaus E.E. Synthesis and biological evaluation of 3,4-diphenyl-1,2,5-oxadiazole-2-oxides and 3,4-diphenyl-1,2,5-oxadiazoles as potential hybrid COX-2 inhibitor/nitric oxide donor agents. Bioorg. Med. Chem. 13 (2005) 2749-2757
    • (2005) Bioorg. Med. Chem. , vol.13 , pp. 2749-2757
    • Velazquez, C.1    Rao, P.N.P.2    McDonald, R.3    Knaus, E.E.4
  • 30
    • 23044450889 scopus 로고    scopus 로고
    • The furoxan system: design of selective nitric oxide (NO) donor inhibitors of COX-2 endowed with anti-aggregatory and vasodilating activities
    • Del Grosso E., Boschi D., Lazzarato L., Cena C., Di Stilo A., Fruttero R., Moro S., and Gasco A. The furoxan system: design of selective nitric oxide (NO) donor inhibitors of COX-2 endowed with anti-aggregatory and vasodilating activities. Chem. Biodivers. 2 (2005) 886-900
    • (2005) Chem. Biodivers. , vol.2 , pp. 886-900
    • Del Grosso, E.1    Boschi, D.2    Lazzarato, L.3    Cena, C.4    Di Stilo, A.5    Fruttero, R.6    Moro, S.7    Gasco, A.8
  • 31
    • 84954358035 scopus 로고    scopus 로고
    • Diazen-1ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-hydroxymethylphenyl)-1-(4-aminosulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its methanesulfonyl analog: synthesis, biological evaluation and nitric oxide release studies
    • Abdellatif K.R.A., Chowdhury M.A., Dong Y., Velazquez C., Das D., Suresh M.R., and Knaus E.E. Diazen-1ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-hydroxymethylphenyl)-1-(4-aminosulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its methanesulfonyl analog: synthesis, biological evaluation and nitric oxide release studies. Bioorg. Med. Chem. 16 (2008) 9694-9698
    • (2008) Bioorg. Med. Chem. , vol.16 , pp. 9694-9698
    • Abdellatif, K.R.A.1    Chowdhury, M.A.2    Dong, Y.3    Velazquez, C.4    Das, D.5    Suresh, M.R.6    Knaus, E.E.7
  • 33
    • 0034057928 scopus 로고    scopus 로고
    • The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action
    • Smith M.L., Hawcroft G., and Hull M.A. The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action. Eur. J. Cancer 36 (2000) 664-674
    • (2000) Eur. J. Cancer , vol.36 , pp. 664-674
    • Smith, M.L.1    Hawcroft, G.2    Hull, M.A.3
  • 34
    • 33748160584 scopus 로고    scopus 로고
    • Risks and benefits of celecoxib to prevent recurrent adenomas
    • Psaty B.M., and Potter J.D. Risks and benefits of celecoxib to prevent recurrent adenomas. N. Engl. J. Med. 355 (2006) 950-952
    • (2006) N. Engl. J. Med. , vol.355 , pp. 950-952
    • Psaty, B.M.1    Potter, J.D.2
  • 35
    • 41949098678 scopus 로고    scopus 로고
    • Growth associated proteins in tumor cells and stroma related to disease progression of colon cancer accounting for tumor tissue PGE2 content
    • Cahlin C., Lönnroth C., Arvidsson A., Nordgren S., and Lundholm K. Growth associated proteins in tumor cells and stroma related to disease progression of colon cancer accounting for tumor tissue PGE2 content. Int. J. Oncol. 32 (2008) 909-918
    • (2008) Int. J. Oncol. , vol.32 , pp. 909-918
    • Cahlin, C.1    Lönnroth, C.2    Arvidsson, A.3    Nordgren, S.4    Lundholm, K.5
  • 37
    • 2442591797 scopus 로고    scopus 로고
    • Celecoxib inhibits phorbol ester-induced expression of COX-2 and activation of AP-1 and p38 MAP kinase in mouse skin
    • Chun K.S., Kim S.H., Song Y.S., and Surh Y.J. Celecoxib inhibits phorbol ester-induced expression of COX-2 and activation of AP-1 and p38 MAP kinase in mouse skin. Carcinogenesis 25 (2004) 713-722
    • (2004) Carcinogenesis , vol.25 , pp. 713-722
    • Chun, K.S.1    Kim, S.H.2    Song, Y.S.3    Surh, Y.J.4
  • 38
    • 17144388620 scopus 로고    scopus 로고
    • Celecoxib decreases endothelial tissue factor expression through inhibition of c-Jun terminal NH2 kinase phosphorylation
    • Steffel J., Hermann M., Greutert H., Gay S., Luscher T.F., Ruschitzka F., and Tunner F.C. Celecoxib decreases endothelial tissue factor expression through inhibition of c-Jun terminal NH2 kinase phosphorylation. Circulation 111 (2005) 1685-1689
    • (2005) Circulation , vol.111 , pp. 1685-1689
    • Steffel, J.1    Hermann, M.2    Greutert, H.3    Gay, S.4    Luscher, T.F.5    Ruschitzka, F.6    Tunner, F.C.7
  • 39
    • 40149084505 scopus 로고    scopus 로고
    • Celecoxib decreases expression of the adhesion molecules ICAM-1 and VCAM-1 in a colon cancer cell line (HT-29)
    • Gallicchio M., Rosa A.C., Dianzani C., Brucato L., Benetti E., Collino M., and Fantozzi R. Celecoxib decreases expression of the adhesion molecules ICAM-1 and VCAM-1 in a colon cancer cell line (HT-29). Br. J. Pharmacol. 153 (2008) 870-878
    • (2008) Br. J. Pharmacol. , vol.153 , pp. 870-878
    • Gallicchio, M.1    Rosa, A.C.2    Dianzani, C.3    Brucato, L.4    Benetti, E.5    Collino, M.6    Fantozzi, R.7
  • 41
    • 2342562556 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases in apoptosis regulation
    • Wada T., and Penninger J.M. Mitogen-activated protein kinases in apoptosis regulation. Oncogene 23 (2004) 2838-2849
    • (2004) Oncogene , vol.23 , pp. 2838-2849
    • Wada, T.1    Penninger, J.M.2
  • 42
    • 13944257829 scopus 로고    scopus 로고
    • Selective inhibitors of MEK1/ERK44/42 and p38 mitogen-activated protein kinases potentiate apoptosis induction by sulindac sulfide in human colon carcinoma cells
    • Sun Y., and Sinicrope F.A. Selective inhibitors of MEK1/ERK44/42 and p38 mitogen-activated protein kinases potentiate apoptosis induction by sulindac sulfide in human colon carcinoma cells. Mol. Cancer Ther. 4 (2005) 51-59
    • (2005) Mol. Cancer Ther. , vol.4 , pp. 51-59
    • Sun, Y.1    Sinicrope, F.A.2
  • 44
    • 23444442691 scopus 로고    scopus 로고
    • Targeting the beta-catenin/APC pathway: a novel mechanism to explain the cyclooxygenase-2-independent anticarcinogenic effects of celecoxib in human colon carcinoma cells
    • Maier T.J., Janssen A., Schmidt R., Geisslinger G., and Grösch S. Targeting the beta-catenin/APC pathway: a novel mechanism to explain the cyclooxygenase-2-independent anticarcinogenic effects of celecoxib in human colon carcinoma cells. FASEB J. 19 (2005) 1353-1355
    • (2005) FASEB J. , vol.19 , pp. 1353-1355
    • Maier, T.J.1    Janssen, A.2    Schmidt, R.3    Geisslinger, G.4    Grösch, S.5
  • 46
    • 0347087570 scopus 로고    scopus 로고
    • Beta-catenin signaling in prostate cancer: an early perspective
    • Chesire D.R., and Isaacs W.B. Beta-catenin signaling in prostate cancer: an early perspective. Endocr. Relat. Cancer 10 (2003) 537-560
    • (2003) Endocr. Relat. Cancer , vol.10 , pp. 537-560
    • Chesire, D.R.1    Isaacs, W.B.2
  • 47
    • 38849201199 scopus 로고    scopus 로고
    • Expression of the cell-cell adhesion molecule beta-catenin in colorectal carcinomas and their metastases
    • Buhmeida A., Elzagheid A., Algars A., Collan Y., Syrjänen K., and Pyrhönen S. Expression of the cell-cell adhesion molecule beta-catenin in colorectal carcinomas and their metastases. APMIS 116 (2008) 1-9
    • (2008) APMIS , vol.116 , pp. 1-9
    • Buhmeida, A.1    Elzagheid, A.2    Algars, A.3    Collan, Y.4    Syrjänen, K.5    Pyrhönen, S.6
  • 48
    • 0036857487 scopus 로고    scopus 로고
    • Effects of etodolac, a selective cyclooxygenase-2 inhibitor, on the expression of E-cadherin-catenin complexes in gastrointestinal cell lines
    • Noda M., Tatsumi Y., Tomizawa M., Takama T., Mitsufuji S., Sugihara H., Kashima K., and Hattori T. Effects of etodolac, a selective cyclooxygenase-2 inhibitor, on the expression of E-cadherin-catenin complexes in gastrointestinal cell lines. J. Gastroenterol. 37 (2002) 896-904
    • (2002) J. Gastroenterol. , vol.37 , pp. 896-904
    • Noda, M.1    Tatsumi, Y.2    Tomizawa, M.3    Takama, T.4    Mitsufuji, S.5    Sugihara, H.6    Kashima, K.7    Hattori, T.8
  • 49
    • 38649142798 scopus 로고    scopus 로고
    • Etodolac, a selective cyclooxygenase-2 inhibitor, induces upregulation of E-cadherin and has antitumor effect on human bladder cancer cells in vitro and in vivo
    • Okamoto A., Shirakawa T., Bito T., Shigemura K., Hamada K., Gotoh A., Fujisawa M., and Kawabata M. Etodolac, a selective cyclooxygenase-2 inhibitor, induces upregulation of E-cadherin and has antitumor effect on human bladder cancer cells in vitro and in vivo. Urology 71 (2008) 156-160
    • (2008) Urology , vol.71 , pp. 156-160
    • Okamoto, A.1    Shirakawa, T.2    Bito, T.3    Shigemura, K.4    Hamada, K.5    Gotoh, A.6    Fujisawa, M.7    Kawabata, M.8
  • 50
    • 0035956850 scopus 로고    scopus 로고
    • Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells
    • Park B.H., Vogelstein B., and Kinzler K.W. Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 2598-2603
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 2598-2603
    • Park, B.H.1    Vogelstein, B.2    Kinzler, K.W.3
  • 52
    • 1942470331 scopus 로고    scopus 로고
    • Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth
    • Gupta R.A., Wang D., Katkuri S., Wang H., Dey S.K., and DuBois R.N. Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth. Nat. Med. 10 (2004) 245-247
    • (2004) Nat. Med. , vol.10 , pp. 245-247
    • Gupta, R.A.1    Wang, D.2    Katkuri, S.3    Wang, H.4    Dey, S.K.5    DuBois, R.N.6
  • 53
    • 4544320012 scopus 로고    scopus 로고
    • Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta
    • Wang D., Wang H., Shi Q., Katkuri S., Walhi W., Desvergne B., Das S.K., Dey S.K., and DuBois R.N. Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta. Cancer Cell. 6 (2004) 285-295
    • (2004) Cancer Cell. , vol.6 , pp. 285-295
    • Wang, D.1    Wang, H.2    Shi, Q.3    Katkuri, S.4    Walhi, W.5    Desvergne, B.6    Das, S.K.7    Dey, S.K.8    DuBois, R.N.9
  • 54
    • 34548412564 scopus 로고    scopus 로고
    • Development of novel agents based on nitric oxide for the control of colon cancer
    • Kozoni V., Rosenberg T., and Rigas B. Development of novel agents based on nitric oxide for the control of colon cancer. Acta Pharmacol. Sin. 28 (2007) 1429-1433
    • (2007) Acta Pharmacol. Sin. , vol.28 , pp. 1429-1433
    • Kozoni, V.1    Rosenberg, T.2    Rigas, B.3
  • 55
    • 36749022313 scopus 로고    scopus 로고
    • Novel agents for cancer prevention based on nitric oxide
    • Rigas B. Novel agents for cancer prevention based on nitric oxide. Biochem. Soc. Trans. 35 (2007) 1364-1368
    • (2007) Biochem. Soc. Trans. , vol.35 , pp. 1364-1368
    • Rigas, B.1
  • 56
    • 0035904231 scopus 로고    scopus 로고
    • E-cadherin regulates cell growth by modulating proliferation-dependent beta-catenin transcriptional activity
    • Stockinger A., Eger A., Wolf J., Beug H., and Foisner R. E-cadherin regulates cell growth by modulating proliferation-dependent beta-catenin transcriptional activity. J. Cell Biol. 154 (2001) 1185-1196
    • (2001) J. Cell Biol. , vol.154 , pp. 1185-1196
    • Stockinger, A.1    Eger, A.2    Wolf, J.3    Beug, H.4    Foisner, R.5
  • 57
    • 2342485121 scopus 로고    scopus 로고
    • MMPs, cadherins, and cell proliferation
    • George S.J., and Dwivedi A. MMPs, cadherins, and cell proliferation. Trends Cardiovasc. Med. 14 (2004) 100-105
    • (2004) Trends Cardiovasc. Med. , vol.14 , pp. 100-105
    • George, S.J.1    Dwivedi, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.