Selective inhibitors of monoamine oxidase. 3. Structure-activity relationship of tricyclics bearing imidazoline, oxadiazole, or tetrazole groups

Journal of Medicinal Chemistry

Volumn 39, Issue 9, 1996, Pages 1857-1863

  Harfenist, Morton ^a   Heuser, Darryl J ^b   Joyner, Charles T ^c   Batchelor, John F ^c   White, Helen L ^a  

^a GLAXOSMITHKLINE   (United States)

^b Analytical Development Laboratories

^c Department of Medicinal Chemistry ^*  (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

IMIDAZOLINE DERIVATIVE; MONOAMINE OXIDASE INHIBITOR; OXADIAZOLE DERIVATIVE; TETRAZOLE DERIVATIVE; TRICYCLIC AROMATIC COMPOUND;

ANIMAL EXPERIMENT; ANXIETY NEUROSIS; ARTICLE; BLOOD PRESSURE; DEPRESSION; DIALYSIS; DRUG ACTIVITY; DRUG EFFECT; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION;

IMIDAZOLES; MONOAMINE OXIDASE INHIBITORS; OXADIAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAZOLES;

EID: 0029874901     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950595m     Document Type: Article

References (12)

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2. Johnston, J. P. Some Observations Upon a New Inhibitor of Monoamine Oxidase in Brain Tissue. Biochem. Pharmacol. 1968, 17, 1285-1297. Squires, R. F. Additional Evidence for the Existence of Several Forms of Mitochondrial Monoamine Oxidase in the Mouse. Biochem. Pharmacol. 1968, 17, 1401-1409.
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