A total synthesis of a new class of biazine thioglycosides

Journal of Carbohydrate Chemistry

Volumn 23, Issue 8-9, 2004, Pages 465-481

  Elgemeie, Galal ^a   Hussein, Mona ^b   Al Khursani, Sheakha ^c  

^a Helwan University   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

^c IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY   (Saudi Arabia)

Author keywords

Antimetabolites; Biazine thioglycosides; Bipyridinyl thioglycosides

Indexed keywords

EID: 33746291074     PISSN: 07328303     EISSN: 15322327     Source Type: Journal    
DOI: 10.1081/CAR-200045262     Document Type: Article

References (7)

1. Elgemeie, G.H.; Mansour, O.A.; Metwally, N.H. Synthesis and anti-HIV activity of different novel nonclassical nucleosides. Nucleosides & Nucleotides 1999, 18, 113-123.
2. Elgemeie, G.H.; Attia, A.M.; Hussain, B.A. A synthetic strategy to a new class of cycloalkane ring-fused pyridine nucleosides as potential anti-HIV agents. Nucleosides & Nucleotides 1998, 17, 855-868.
3. Elgemeie, G.H.; Hussain, B.A. A convenient synthesis of 5-deaza nonclassical anti-folates: reaction of cyanothioacetamide with sodium salts of 2-(hydroxymethylene)-1-cycloalkanones. Tetrahedron 1994, 50, 199-204.
4. Elgemeie, G.H.; Attia, A.M.; Farag, D.S.; Sherif, S.M. Nucleotides and nucleosides: direct route to condensed pyridinethione carbocyclic nucleosides related to 3-deazauridine. J. Chem. Soc. Perkin Trans. 1 1994, 1285-1288.
5. Elgemeie, G.E.H.; Attia, A.M.; Shehada, L.A. Synthesis of some novel condensed pyridine-2(1H)-thiones and related glycosides. Tetrahedron 1997, 53, 17441-17448.
6. Scala, S.; Akhmed, N.; Rao, U.S.; Paull, K.; Lan, L.; Dickstein, B.; Lee, J.; Elgemeie, G.E.H.; Stein, W.D.; and Bates, S.E.P. Glycoprotein substrates and antagonists cluster into two distinct groups. Mol. Pharmacol. 1977, 51, 1024-1033.
7. Elgemeie, G.H.; Hussein, M.M.; Jones, P.G. 2-(2′,3′,4′, 6′-Tetra-O-acetyl-β-D-glucopyranosylthio-4-pyridin-4-yl-6,7,8, 9-tetrahydro-5H-cyclo-hepta[b]pyridin-3-carbonitrile. Acta Cryst. 2002, E58, 1244-1246.