The effect of drugs with ion channel-blocking activity on the early embryonic rat heart

Birth Defects Research Part B - Developmental and Reproductive Toxicology

Volumn 89, Issue 5, 2010, Pages 429-440

  Abela, Dominique ^a   Ritchie, Helen ^a   Ababneh, Deena ^a   Gavin, Caroline ^a   Nilsson, Mats F ^b   Khan, Muhammad Khalid ^b   Carlsson, Kristin ^a   Webster, William S ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Embryo fetal physiology; In vitro screens; Mechanisms of teratogenesis; Pharmaceuticals

Indexed keywords

AMIODARONE; AMITRIPTYLINE; ATENOLOL; CALCIUM CHANNEL BLOCKING AGENT; DISOPYRAMIDE; DOFETILIDE; FLECAINIDE; INDAPAMIDE; LIDOCAINE; MIBEFRADIL; NICKEL CHLORIDE; NIFEDIPINE; NIFLUMIC ACID; PHENYTOIN; POTASSIUM CHANNEL BLOCKING AGENT; QUINIDINE; SODIUM CHANNEL BLOCKING AGENT; VERAPAMIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRADYCARDIA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG PROTEIN BINDING; DRUG SPECIFICITY; EMBRYO; EMBRYO CULTURE; EMBRYO DEVELOPMENT; FEMALE; GESTATIONAL AGE; HEART ARRHYTHMIA; HEART ATRIUM; HEART BEAT; HEART CONTRACTION; HEART VENTRICLE; IN VITRO STUDY; INOTROPISM; NONHUMAN; POLYPHARMACY; PREDICTION; PRIORITY JOURNAL; RAT;

ABNORMALITIES, DRUG-INDUCED; ANIMALS; ANOXIA; ARRHYTHMIAS, CARDIAC; BRADYCARDIA; EMBRYO CULTURE TECHNIQUES; FEMALE; HEART; MALE; PHENYTOIN; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, VOLTAGE-GATED; PREGNANCY; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 78650487837     PISSN: 15429733     EISSN: 15429741     Source Type: Journal    
DOI: 10.1002/bdrb.20270     Document Type: Article

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