Inhibitory effect of erythromycin on potassium currents in rat ventricular myocytes in comparison with disopyramide

Journal of Pharmacy and Pharmacology

Volumn 55, Issue 7, 2003, Pages 995-1002

  Hanada, Erika ^a   Ohtani, Hisakazu ^b   Hirota, Michiko ^a   Uemura, Noriko ^c   Nakaya, Haruaki ^c   Kotaki, Hajime ^d   Sato, Hitoshi ^e   Yamada, Yasuhiko ^a   Iga, Tatsuji ^a  

^a UNIVERSITY OF TOKYO HOSPITAL   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c CHIBA UNIVERSITY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e SHOWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIARRHYTHMIC AGENT; DISOPYRAMIDE; ERYTHROMYCIN; MACROLIDE;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DELAYED RECTIFIER POTASSIUM CURRENT; DOSE RESPONSE; DRUG EFFECT; DRUG INDUCED DISEASE; DRUG POTENCY; DRUG UPTAKE; ENZYMATIC ASSAY; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE POTENTIAL; HEART REPOLARIZATION; HEART VENTRICLE; IC 50; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; LONG QT SYNDROME; MALE; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; RAT; TRANSIENT OUTWARD POTASSIUM CURRENT;

ACTION POTENTIALS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; ANTI-BACTERIAL AGENTS; DELAYED RECTIFIER POTASSIUM CHANNELS; DISOPYRAMIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROMYCIN; LONG QT SYNDROME; MALE; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0041664962     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357021459     Document Type: Article

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