The antipsychotic agent sertindole is a high affinity antagonist of the human cardiac potassium channel HERG

Journal of Pharmacology and Experimental Therapeutics

Volumn 286, Issue 2, 1998, Pages 788-793

  Rampe, David ^a   Murawsky, Michael K ^a   Grau, Jessica ^a   Lewis, Eric W ^a  

^a SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROLEPTIC AGENT; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; SERTINDOLE;

ARTICLE; HEART ELECTROPHYSIOLOGY; HEART VENTRICLE ARRHYTHMIA; HUMAN; HUMAN CELL; LIGAND BINDING; LONG QT SYNDROME; PRIORITY JOURNAL; QT INTERVAL;

ANTIPSYCHOTIC AGENTS; CATION TRANSPORT PROTEINS; CLONING, MOLECULAR; DNA-BINDING PROTEINS; ELECTROPHYSIOLOGY; ETHER-A-GO-GO POTASSIUM CHANNELS; HEART; HUMANS; IMIDAZOLES; INDOLES; KV1.5 POTASSIUM CHANNEL; MEMBRANE POTENTIALS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; TRANS-ACTIVATORS;

EID: 0032410714     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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