3-Ketoacyl thiolase delays aging of Caenorhabditis elegans and is required for lifespan extension mediated by sir-2.1

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 44, 2010, Pages 18927-18932

  Berdichevsky, Alina ^b   Nedelcu, Simona ^a   Boulias, Konstantinos ^a   Bishop, Nicholas A ^c   Guarente, Leonard ^a   Horvitz, H Robert ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^c Cowen and Company ^*  (United States)

Author keywords

Fatty acid oxidation; Lipofuscin; Progeria; Protein deacetylation; Sirtuins

Indexed keywords

3 KETOACYL THIOLASE; ACETYL COENZYME A ACYLTRANSFERASE; ASPARTOACYLASE; FATTY ACID; LIPOFUSCIN; SILENT INFORMATION REGULATOR PROTEIN 2; UNCLASSIFIED DRUG;

AGING; ANIMAL EXPERIMENT; BACTERIUM MUTANT; BEHAVIOR; CAENORHABDITIS ELEGANS; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME MECHANISM; FATTY ACID OXIDATION; GENE MUTATION; GENETIC SCREENING; HEAT TOLERANCE; HERMAPHRODITIC SPECIES; LIFE EXTENSION; LIPID STORAGE; LONGEVITY; LOSS OF FUNCTION MUTATION; NONHUMAN; PREMATURE AGING; PRIORITY JOURNAL; WORM;

CAENORHABDITIS ELEGANS;

EID: 78650448343     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1013854107     Document Type: Article

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