Oestrogen prevents cardiomyocyte apoptosis by suppressing p38α-mediated activation of p53 and by down-regulating p53 inhibition on p38β

Cardiovascular Research

Volumn 89, Issue 1, 2011, Pages 119-128

  Liu, Han ^a   Pedram, Ali ^a   Kim, Jin Kyung ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apoptosis; Cardiomyocyte; Oestrogen; p38; p53

Indexed keywords

ANTIOXIDANT; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; MITOGEN ACTIVATED PROTEIN KINASE 11; MITOGEN ACTIVATED PROTEIN KINASE 14; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SERINE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; CELL HYPOXIA; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HEART; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; REGULATORY MECHANISM; REOXYGENATION; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CELL HYPOXIA; CELL SURVIVAL; CELLS, CULTURED; DOWN-REGULATION; ENZYME ACTIVATION; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEMALE; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 11; MITOGEN-ACTIVATED PROTEIN KINASE 14; MODELS, CARDIOVASCULAR; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; RATS; REACTIVE OXYGEN SPECIES; SEX CHARACTERISTICS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 78650431640     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvq265     Document Type: Article

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