메뉴 건너뛰기




Volumn 297, Issue 5, 2009, Pages

Activation of a novel estrogen receptor, GPER, is cardioprotective in male and female rats

Author keywords

G protein coupled estrogen receptor; G protein coupled receptor 30; G 1; Ischemia reperfusion; Langendorff

Indexed keywords

ESTROGEN RECEPTOR; G 1; HORMONE ANTAGONIST; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN GPER; PROTEIN KINASE B; UNCLASSIFIED DRUG; WORTMANNIN;

EID: 70350448860     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00283.2009     Document Type: Article
Times cited : (217)

References (37)
  • 1
    • 1842867053 scopus 로고    scopus 로고
    • Effects of Conjugated Equine Estrogen in Postmenopausal Women with Hysterectomy: The Women's Health Initiative Randomized Controlled Trial
    • DOI 10.1001/jama.291.14.1701
    • Anderson GL, Limacher M, Assaf AR, Bassford T, Beresford SA, Black H, Bonds D, Brunner R, Brzyski R, Caan B, Chlebowski R, Curb D, Gass M, Hays J, Heiss G, Hendrix S, Howard BV, Hsia J, Hubbell A, Jackson R, Johnson KC, Judd H, Kotchen JM, Kuller L, LaCroix AZ, Lane D, Langer RD, Lasser N, Lewis CE, Manson J, Margolis K, Ockene J, O'Sullivan MJ, Phillips L, Prentice RL, Ritenbaugh C, Robbins J, Rossouw JE, Sarto G, Stefanick ML, Van Horn L, Wactawski-Wende J, Wallace R, Wassertheil-Smoller S. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA 291: 1701-1712, 2004. (Pubitemid 38489892)
    • (2004) Journal of the American Medical Association , vol.291 , Issue.14 , pp. 1701-1712
    • Anderson, G.L.1    Limacher, M.2
  • 2
    • 0031024219 scopus 로고    scopus 로고
    • Sex differences in coronary heart disease: Why are women so superior? The 1995 ancel keys lecture
    • Barrett-Connor E. Sex differences in coronary heart disease: why are women so superior? The 1995 ancel keys lecture. Circulation 95: 252-264, 1997.
    • (1997) Circulation , vol.95 , pp. 252-264
    • Barrett-Connor, E.1
  • 3
    • 14244258686 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II and epidermal growth factor receptor
    • DOI 10.1007/s11010-005-3895-1
    • Benter IF, Juggi JS, Khan I, Yousif MH, Canatan H, Akhtar S. Signal transduction mechanisms involved in cardiac preconditioning: role of Ras-GTPase, Ca2+/calmodulin-dependent protein kinase II and epidermal growth factor receptor. Mol Cell Biochem 268: 175-183, 2005. (Pubitemid 40287840)
    • (2005) Molecular and Cellular Biochemistry , vol.268 , Issue.1-2 , pp. 175-183
    • Benter, I.F.1    Juggi, J.S.2    Khan, I.3    Yousif, M.H.M.4    Canatan, H.5    Akhtar, S.6
  • 5
    • 34250322219 scopus 로고    scopus 로고
    • Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system
    • Brailoiu E, Dun SL, Brailoiu GC, Mizuo K, Sklar LA, Oprea TI, Prossnitz ER, Dun NJ. Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system. J Endocrinol 193: 311-321, 2007.
    • (2007) J Endocrinol , vol.193 , pp. 311-321
    • Brailoiu, E.1    Dun, S.L.2    Brailoiu, G.C.3    Mizuo, K.4    Sklar, L.A.5    Oprea, T.I.6    Prossnitz, E.R.7    Dun, N.J.8
  • 6
  • 7
    • 0030786202 scopus 로고    scopus 로고
    • Conditional inhibition of the mitogen-activated protein kinase cascade by wortmannin. Dependence on signal strength
    • Duckworth BC, Cantley LC. Conditional inhibition of the mitogen-activated protein kinase cascade by wortmannin. Dependence on signal strength. J Biol Chem 272: 27665-27670, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 27665-27670
    • Duckworth, B.C.1    Cantley, L.C.2
  • 8
    • 0033780783 scopus 로고    scopus 로고
    • Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF
    • Filardo EJ, Quinn JA, Bland KI, Frackelton AR Jr. Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF. Mol Endocrinol 14: 1649-1660, 2000.
    • (2000) Mol Endocrinol , vol.14 , pp. 1649-1660
    • Filardo, E.J.1    Quinn, J.A.2    Bland, K.I.3    Frackelton Jr., A.R.4
  • 9
    • 0036140032 scopus 로고    scopus 로고
    • Estrogen action via the G protein-coupled receptor, GPR30: Stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to- MAPK signaling axis
    • Filardo EJ, Quinn JA, Frackelton AR Jr, Bland KI. Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to- MAPK signaling axis. Mol Endocrinol 16: 70-84, 2002.
    • (2002) Mol Endocrinol , vol.16 , pp. 70-84
    • Filardo, E.J.1    Quinn, J.A.2    Frackelton Jr., A.R.3    Bland, K.I.4
  • 11
    • 0029780938 scopus 로고    scopus 로고
    • Beta-Estradiol, but not alpha-estradiol, reduces myocardial necrosis in rabbits after ischemia and reperfusion
    • DOI 10.1016/S0002-8703(96)90419-6
    • Hale SL, Birnbaum Y, Kloner RA. Beta-estradiol, but not alpha-estradiol, reduced myocardial necrosis in rabbits after ischemia and reperfusion. Am Heart J 132: 258-262, 1996. (Pubitemid 26292388)
    • (1996) American Heart Journal , vol.132 , Issue.2 I , pp. 258-262
    • Hale, S.L.1    Birnbaum, Y.2    Kloner, R.A.3
  • 13
    • 34547095758 scopus 로고    scopus 로고
    • Nongenomic, endothelium-independent effects of estrogen on human coronary smooth muscle are mediated by type I (neuronal) NOS and PI3-kinase-Akt signaling
    • Han G, Ma H, Chintala R, Miyake K, Fulton DJR, Barman SA, White RE. Nongenomic, endothelium-independent effects of estrogen on human coronary smooth muscle are mediated by type I (neuronal) NOS and PI3-kinase-Akt signaling. Am J Physiol Heart Circ Physiol 293: H314-H321, 2007.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Han, G.1    Ma, H.2    Chintala, R.3    Miyake, K.4    Fulton, D.J.R.5    Barman, S.A.6    White, R.E.7
  • 14
    • 23444452869 scopus 로고    scopus 로고
    • Mechanisms of erythropoietin-mediated cardioprotection during ischemia-reperfusion injury: Role of protein kinase C and phosphatidylinositol 3-kinase signaling
    • DOI 10.1096/fj.04-3545fje
    • Hanlon PR, Fu P, Wright GL, Steenbergen C, Arcasoy MO, Murphy E. Mechanisms of erythropoietin-mediated cardioprotection during ischemia- reperfusion injury: role of protein kinase C and phosphatidylinositol 3-kinase signaling. FASEB J 19: 1323-1325, 2005. (Pubitemid 41113737)
    • (2005) FASEB Journal , vol.19 , Issue.10 , pp. 1323-1325
    • Hanlon, P.R.1    Fu, P.2    Wright, G.L.3    Steenbergen, C.4    Arcasoy, M.O.5    Murphy, E.6
  • 15
    • 1142309743 scopus 로고    scopus 로고
    • New directions for protecting the heart against ischaemia-reperfusion injury: Targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway
    • Hausenloy DJ, Yellon DM. New directions for protecting the heart against ischaemia-reperfusion injury: targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway. Cardiovasc Res 61: 448-460, 2004.
    • (2004) Cardiovasc Res , vol.61 , pp. 448-460
    • Hausenloy, D.J.1    Yellon, D.M.2
  • 16
    • 0032547326 scopus 로고    scopus 로고
    • Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group
    • Hulley S, Grady D, Bush T, Furberg C, Herrington D, Riggs B, Vittinghoff E. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. JAMA 280: 605-613, 1998.
    • (1998) JAMA , vol.280 , pp. 605-613
    • Hulley, S.1    Grady, D.2    Bush, T.3    Furberg, C.4    Herrington, D.5    Riggs, B.6    Vittinghoff, E.7
  • 20
    • 0034698358 scopus 로고    scopus 로고
    • Putative membrane-bound estrogen receptors possibly stimulate mitogen-activated protein kinase in the rat hippocampus
    • DOI 10.1016/S0014-2999(00)00425-8, PII S0014299900004258
    • Kuroki Y, Fukushima K, Kanda Y, Mizuno K, Watanabe Y. Putative membrane-bound estrogen receptors possibly stimulate mitogen-activated protein kinase in the rat hippocampus. Eur J Pharmacol 400: 205-209, 2000. (Pubitemid 30438728)
    • (2000) European Journal of Pharmacology , vol.400 , Issue.2-3 , pp. 205-209
    • Kuroki, Y.1    Fukushima, K.2    Kanda, Y.3    Mizuno, K.4    Watanabe, Y.5
  • 23
    • 0033542402 scopus 로고    scopus 로고
    • The protective effects of estrogen on the cardiovascular system
    • Mendelsohn ME, Karas RH. The protective effects of estrogen on the cardiovascular system. N Engl J Med 340: 1801-1811, 1999.
    • (1999) N Engl J Med , vol.340 , pp. 1801-1811
    • Mendelsohn, M.E.1    Karas, R.H.2
  • 24
    • 1642349571 scopus 로고    scopus 로고
    • Tamoxifen and ICI 182,780 negatively influenced cardiac cell growth via an estrogen receptor-independent mechanism
    • DOI 10.1016/S0008-6363(03)00517-0, PII S0008636303005170
    • Mercier I, Mader S, Calderone A. Tamoxifen and ICI 182,780 negatively influenced cardiac cell growth via an estrogen receptor-independent mechanism. Cardiovasc Res 59: 883-892, 2003. (Pubitemid 38366244)
    • (2003) Cardiovascular Research , vol.59 , Issue.4 , pp. 883-892
    • Mercier, I.1    Mader, S.2    Calderone, A.3
  • 25
    • 67449152265 scopus 로고    scopus 로고
    • Non-genomic regulation of vascular cell function and growth by estrogen
    • Meyer MR, Haas E, Prossnitz ER, Barton M. Non-genomic regulation of vascular cell function and growth by estrogen. Mol Cell Endocrinol 308: 9-16, 2009.
    • (2009) Mol Cell Endocrinol , vol.308 , pp. 9-16
    • Meyer, M.R.1    Haas, E.2    Prossnitz, E.R.3    Barton, M.4
  • 29
    • 41549156954 scopus 로고    scopus 로고
    • PI3 kinase/Akt activation mediates estrogen and IGF-1 nigral DA neuronal neuroprotection against a unilateral rat model of Parkinson's disease
    • Quesada A, Lee BY, Micevych PE. PI3 kinase/Akt activation mediates estrogen and IGF-1 nigral DA neuronal neuroprotection against a unilateral rat model of Parkinson's disease. Dev Neurobiol 68: 632-644, 2008.
    • (2008) Dev Neurobiol , vol.68 , pp. 632-644
    • Quesada, A.1    Lee, B.Y.2    Micevych, P.E.3
  • 30
    • 14844343093 scopus 로고    scopus 로고
    • A transmembrane intracellular estrogen receptor mediates rapid cell signaling
    • Revankar CM, Cimino DF, Sklar LA, Arterburn JB, Prossnitz ER. A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science 307: 1625-1630, 2005.
    • (2005) Science , vol.307 , pp. 1625-1630
    • Revankar, C.M.1    Cimino, D.F.2    Sklar, L.A.3    Arterburn, J.B.4    Prossnitz, E.R.5
  • 31
    • 37849031206 scopus 로고    scopus 로고
    • Signal strength dictates phosphoinositide 3-kinase contribution to Ras/extracellular signal-regulated kinase 1 and 2 activation via differential Gab1/Shp2 recruitment: Consequences for resistance to epidermal growth factor receptor inhibition
    • Sampaio C, Dance M, Montagner A, Edouard T, Malet N, Perret B, Yart A, Salles JP, Raynal P. Signal strength dictates phosphoinositide 3-kinase contribution to Ras/extracellular signal-regulated kinase 1 and 2 activation via differential Gab1/Shp2 recruitment: consequences for resistance to epidermal growth factor receptor inhibition. Mol Cell Biol 28: 587-600, 2008.
    • (2008) Mol Cell Biol , vol.28 , pp. 587-600
    • Sampaio, C.1    Dance, M.2    Montagner, A.3    Edouard, T.4    Malet, N.5    Perret, B.6    Yart, A.7    Salles, J.P.8    Raynal, P.9
  • 32
    • 0034727094 scopus 로고    scopus 로고
    • Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase
    • DOI 10.1038/35035131
    • Simoncini T, Hafezi-Moghadam A, Brazil DP, Ley K, Chin WW, Liao JK. Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature 407: 538-541, 2000. (Pubitemid 30746711)
    • (2000) Nature , vol.407 , Issue.6803 , pp. 538-541
    • Simoncini, T.1    Hafezi-Moghadam, A.2    Brazil, D.P.3    Ley, K.4    Chin, W.W.5    Llao, J.K.6
  • 34
    • 2342516104 scopus 로고    scopus 로고
    • G Protein-Coupled Receptor Internalization Signaling Is Required for Cardioprotection in Ischemic Preconditioning
    • DOI 10.1161/01.RES.0000126048.32383.6B
    • Tong H, Rockman HA, Koch WJ, Steenbergen C, Murphy E. G protein-coupled receptor internalization signaling is required for cardioprotection in ischemic preconditioning. Circ Res 94: 1133-1141, 2004. (Pubitemid 38579709)
    • (2004) Circulation Research , vol.94 , Issue.8 , pp. 1133-1141
    • Tong, H.1    Rockman, H.A.2    Koch, W.J.3    Steenbergen, C.4    Murphy, E.5
  • 35
    • 49249091516 scopus 로고    scopus 로고
    • Genomic deletion of estrogen receptors ER-α and ER-β does not alter estrogen-mediated inhibition of Ca2+ influx and contraction in murine cardiomyocytes
    • Ullrich ND, Krust A, Collins P, MacLeod KT. Genomic deletion of estrogen receptors ER-α and ER-β does not alter estrogen-mediated inhibition of Ca2+ influx and contraction in murine cardiomyocytes. Am J Physiol Heart Circ Physiol 294: H2421-H2427, 2008.
    • (2008) Am J Physiol Heart Circ Physiol , vol.294
    • Ullrich, N.D.1    Krust, A.2    Collins, P.3    MacLeod, K.T.4
  • 36
    • 33344461590 scopus 로고    scopus 로고
    • The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17β-estradiol and hydroxytamoxifen in endometrial cancer cells
    • DOI 10.1210/me.2005-0280
    • Vivacqua A, Bonofiglio D, Recchia AG, Musti AM, Picard D, Ando S, Maggiolini M. The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17β-estradiol and hydroxytamoxifen in endometrial cancer cells. Mol Endocrinol 20: 631-646, 2006. (Pubitemid 43291214)
    • (2006) Molecular Endocrinology , vol.20 , Issue.3 , pp. 631-646
    • Vivacqua, A.1    Bonofiglio, D.2    Recchia, A.G.3    Musti, A.M.4    Picard, D.5    Ando, S.6    Maggiolini, M.7
  • 37
    • 6344225691 scopus 로고    scopus 로고
    • Erythropoiet in receptor expression in adult rat cardiomyocytes is associated with an acute cardioprotective effect for recombinant erythropoietin during ischemia-reperfusion injury
    • DOI 10.1096/fj.03-1289fje
    • Wright GL, Hanlon P, Amin K, Steenbergen C, Murphy E, Arcasoy MO. Erythropoietin receptor expression in adult rat cardiomyocytes is associated with an acute cardioprotective effect for recombinant erythropoietin during ischemia-reperfusion injury. FASEB J 18: 1031-1033, 2004. (Pubitemid 39561515)
    • (2004) FASEB Journal , vol.18 , Issue.9 , pp. 1031-1033
    • Wright, G.L.1    Hanlon, P.2    Amin, K.3    Steenbergen, C.4    Murphy, E.5    Arcasoy, M.O.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.