Homology modeling and screening of new 14α-demethylase inhibitor (DMI) fungicides based on optimized expression of CYP51 from ustilago maydis in Escherichia coli

Journal of Agricultural and Food Chemistry

Volumn 58, Issue 24, 2010, Pages 12810-12816

  Han, Rui ^a,b   Zhang, Jianhua ^a   Li, Shuxiang ^a   Cao, Shufen ^a   Geng, Hui ^a   Yuan, Yongze ^a   Xiao, Wenjing ^c   Liu, Shenghua ^c   Liu, Deli ^a,c  

^a CENTRAL CHINA NORMAL UNIVERSITY   (China)

^b QINGHAI UNIVERSITY   (China)

^c BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

CYP51; DMI fungicides; homology modeling; optimized expression; site directed mutagenesis; Ustilago maydis

Indexed keywords

CYP51; DMI FUNGICIDES; HOMOLOGY MODELING; OPTIMIZED EXPRESSION; SITE-DIRECTED MUTAGENESIS; USTILAGO MAYDIS;

AGRICULTURAL CHEMICALS; ALCOHOLS; BIOCHEMISTRY; DRUG INTERACTIONS; ESCHERICHIA COLI; MUTAGENESIS; OPTIMIZATION; PLANTS (BOTANY);

FUNGICIDES;

FUNGAL PROTEIN; FUNGICIDE; STEROL 14ALPHA DEMETHYLASE; STEROL 14ALPHA DEMETHYLASE INHIBITOR;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG SCREENING; ENZYMOLOGY; ESCHERICHIA COLI; GENE EXPRESSION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; SEQUENCE ALIGNMENT; USTILAGO;

14-ALPHA DEMETHYLASE INHIBITORS; AMINO ACID SEQUENCE; DRUG EVALUATION, PRECLINICAL; ESCHERICHIA COLI; FUNGAL PROTEINS; FUNGICIDES, INDUSTRIAL; GENE EXPRESSION; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; SEQUENCE ALIGNMENT; STEROL 14-DEMETHYLASE; USTILAGO;

ESCHERICHIA COLI; EUKARYOTA; USTILAGO MAYDIS; ZEA MAYS;

EID: 78650400995     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf103243m     Document Type: Article

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