Organocatalytic synthesis and sterol 14α-demethylase binding interactions of enantioriched 3-(1H-1,2,4-triazol-1-yl)butyl benzoates

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 14, 2009, Pages 3938-3940

  Ming, Zhi Hui ^a   Xu, Sheng Zhen ^a   Zhou, Lei ^a   Ding, Ming Wu ^a   Yang, Jiao Yan ^a   Yang, Shao ^a   Xiao, Wen Jing ^a  

^a CENTRAL CHINA NORMAL UNIVERSITY   (China)

Author keywords

CYP51; Michael addition; Organocatalysis; Triazole

Indexed keywords

3 (1H 1,2,4 TRIAZOL 1 YL)BUTYL BENZOATE; BENZOIC ACID DERIVATIVE; CROTONALDEHYDE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; PROLINE DERIVATIVE; SILANE DERIVATIVE; STEROL 14ALPHA DEMETHYLASE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CATALYSIS; ENANTIOMER; ENANTIOSELECTIVITY; QUANTUM YIELD; REACTION ANALYSIS; SYNTHESIS;

ALDEHYDES; ANTIFUNGAL AGENTS; BENZOATES; CYTOCHROME P-450 ENZYME SYSTEM; STEREOISOMERISM; TRIAZOLES;

EID: 67649875029     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.03.028     Document Type: Article

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