Oolong tea theasinensins attenuate cyclooxygenase-2 expression in lipopolysaccharide (LPS)-activated mouse macrophages: Structure-activity relationship and molecular mechanisms

Journal of Agricultural and Food Chemistry

Volumn 58, Issue 24, 2010, Pages 12735-12743

  Hou, De Xing ^a   Masuzaki, Satoko ^a   Tanigawa, Shunsuke ^a   Hashimoto, Fumio ^a   Chen, Jihua ^a   Sogo, Takayuki ^a   Fujii, Makoto ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

cyclooxygenase 2; MAPK; NF B; Oolong tea; theasinensins

Indexed keywords

ANTI-INFLAMMATORIES; BLACK TEA; CYCLOOXYGENASE 2; DOSE-DEPENDENT; DOWN-REGULATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GREEN TEA; INHIBITORY EFFECT; LIPOPOLYSACCHARIDES; MAPK; MOLECULAR BASIS; MOLECULAR MECHANISM; MURINE MACROPHAGES; OOLONG TEA; POTENT INHIBITOR; PROMOTER ACTIVITIES; SIGNALING PATHWAYS; STRUCTURE ACTIVITY RELATIONSHIPS; STRUCTURE-ACTIVITY; TEA POLYPHENOLS; THEAFLAVINS; THEASINENSINS;

ENZYMES; MACROPHAGES; NUCLEIC ACIDS; PHENOLS; PHOSPHORYLATION; SIGNALING;

ELECTROPHORETIC MOBILITY;

ANTIINFLAMMATORY AGENT; BENZOPYRAN DERIVATIVE; CYCLOOXYGENASE 2; LIPOPOLYSACCHARIDE; PHENOL DERIVATIVE; PLANT EXTRACT; THEASINENSIN A;

ANIMAL; ARTICLE; CELL LINE; CHEMISTRY; DOWN REGULATION; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; MACROPHAGE; METABOLISM; MOUSE; PROMOTER REGION; STRUCTURE ACTIVITY RELATION; TEA;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BENZOPYRANS; CELL LINE; CYCLOOXYGENASE 2; DOWN-REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; PHENOLS; PLANT EXTRACTS; PROMOTER REGIONS, GENETIC; STRUCTURE-ACTIVITY RELATIONSHIP; TEA;

CAMELLIA SINENSIS; MURINAE;

EID: 78650336464     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf103605j     Document Type: Article

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